Morris F. Manolson - Publications

Affiliations: 
Dentistry University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology, Cell Biology, Oncology

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Chu A, Yao Y, Glibowicka M, Deber CM, Manolson MF. The Human Mutation K237_V238del in a Putative Lipid Binding Motif within the V-ATPase a2 Isoform Suggests a Molecular Mechanism Underlying Cutis Laxa. International Journal of Molecular Sciences. 25. PMID 38396846 DOI: 10.3390/ijms25042170  0.421
2021 Oot RA, Yao Y, Manolson MF, Wilkens S. Purification of active human vacuolar ATPase in native lipid-containing nanodiscs. The Journal of Biological Chemistry. 100964. PMID 34270960 DOI: 10.1016/j.jbc.2021.100964  0.365
2021 Chu A, Zirngibl RA, Manolson MF. The V-ATPase 3 Subunit: Structure, Function and Therapeutic Potential of an Essential Biomolecule in Osteoclastic Bone Resorption. International Journal of Molecular Sciences. 22. PMID 34203247 DOI: 10.3390/ijms22136934  0.305
2019 Zirngibl RA, Wang A, Yao Y, Manolson MF, Krueger J, Dupuis L, Mendoza-Londono R, Voronov I. Novel c.G630A TCIRG1 mutation causes aberrant splicing resulting in an unusually mild form of autosomal recessive osteopetrosis. Journal of Cellular Biochemistry. PMID 31111556 DOI: 10.1002/Jcb.28979  0.382
2018 Esmail S, Kartner N, Yao Y, Kim JW, Reithmeier RAF, Manolson MF. Molecular mechanisms of cutis laxa and distal renal tubular acidosis-causing mutations in V-ATPase a subunits, ATP6V0A2 and ATP6V0A4. The Journal of Biological Chemistry. PMID 29311258 DOI: 10.1074/Jbc.M117.818872  0.539
2017 Esmail S, Kartner N, Yao Y, Kim JW, Reithmeier RAF, Manolson MF. N-linked Glycosylation of a Subunit Isoforms is Critical for Vertebrate Vacuolar H(+) -ATPase (V-ATPase) Biosynthesis. Journal of Cellular Biochemistry. PMID 28661051 DOI: 10.1002/Jcb.26250  0.508
2016 Esmail S, Yao Y, Kartner N, Li J, Reithmeier RA, Manolson MF. N-Linked Glycosylation Is Required for Vacuolar H(+) -ATPase (V-ATPase) a4 Subunit Stability, Assembly, and Cell Surface Expression. Journal of Cellular Biochemistry. PMID 27127844 DOI: 10.1002/Jcb.25574  0.535
2015 Bernard D, Gebbia M, Prabha S, Gronda M, MacLean N, Wang X, Hurren R, Sukhai MA, Cho EE, Manolson MF, Datti A, Wrana J, Minden MD, Al-Awar R, Aman A, et al. Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells. Apoptosis : An International Journal On Programmed Cell Death. 20: 948-59. PMID 25832785 DOI: 10.1007/S10495-015-1123-3  0.308
2013 Ochotny N, Voronov I, Owen C, Aubin JE, Manolson MF. The R740S mutation in the V-ATPase a3 subunit results in osteoclast apoptosis and defective early-stage autophagy. Journal of Cellular Biochemistry. 114: 2823-33. PMID 23908015 DOI: 10.1002/Jcb.24630  0.734
2013 Ramachandran N, Munteanu I, Wang P, Ruggieri A, Rilstone JJ, Israelian N, Naranian T, Paroutis P, Guo R, Ren ZP, Nishino I, Chabrol B, Pellissier JF, Minetti C, Udd B, ... ... Manolson MF, et al. VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy. Acta Neuropathologica. 125: 439-57. PMID 23315026 DOI: 10.1007/S00401-012-1073-6  0.362
2013 Kartner N, Yao Y, Bhargava A, Manolson MF. Topology, glycosylation and conformational changes in the membrane domain of the vacuolar H+-ATPase a subunit Journal of Cellular Biochemistry. 114: 1474-1487. PMID 23296946 DOI: 10.1002/Jcb.24489  0.322
2013 Crasto GJ, Kartner N, Yao Y, Li K, Bullock L, Datti A, Manolson MF. Luteolin inhibition of V-ATPase a3-d2 interaction decreases osteoclast resorptive activity. Journal of Cellular Biochemistry. 114: 929-41. PMID 23129004 DOI: 10.1002/Jcb.24434  0.505
2013 Voronov I, Ochotny N, Jaumouillé V, Owen C, Manolson MF, Aubin JE. The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 108-18. PMID 22865292 DOI: 10.1002/Jbmr.1727  0.755
2013 Bernard D, Gebbia M, Prabha S, Gronda M, MacLean N, Wang X, Hurren R, Sukhai MA, Cho EE, Manolson MF, Datti A, Wrana J, Al-Awar R, Aman A, Nislow C, et al. Abstract A299: Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A299  0.406
2012 Bhargava A, Voronov I, Wang Y, Glogauer M, Kartner N, Manolson MF. Osteopetrosis mutation R444L causes endoplasmic reticulum retention and misprocessing of vacuolar H+-ATPase a3 subunit. The Journal of Biological Chemistry. 287: 26829-39. PMID 22685294 DOI: 10.1074/Jbc.M112.345702  0.507
2012 Kartner N, Manolson MF. V-ATPase subunit interactions: the long road to therapeutic targeting. Current Protein & Peptide Science. 13: 164-79. PMID 22044155 DOI: 10.2174/138920312800493179  0.462
2011 Ochotny N, Flenniken AM, Owen C, Voronov I, Zirngibl RA, Osborne LR, Henderson JE, Adamson SL, Rossant J, Manolson MF, Aubin JE. The V-ATPase a3 subunit mutation R740S is dominant negative and results in osteopetrosis in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1484-93. PMID 21305608 DOI: 10.1002/Jbmr.355  0.768
2010 Ramachandran N, Munteanu I, Wang P, Aubourg P, Rilstone JJ, Israelian N, Naranian T, Paroutis P, Guo R, Ren ZP, Nishino I, Chabrol B, Pellissier JF, Minetti C, Udd B, ... ... Manolson MF, et al. Erratum to Retraction Notice to: VMA21 Deficiency Causes an Autophagic Myopathy by Compromising V-ATPase Activity and Lysosomal Acidification [Cell, 137, (2009), 235-246] Cell. 142. PMID 20873370 DOI: 10.1016/J.Cell.2010.08.034  0.397
2010 Kartner N, Yao Y, Li K, Crasto GJ, Datti A, Manolson MF. Inhibition of osteoclast bone resorption by disrupting vacuolar H+-ATPase a3-B2 subunit interaction. The Journal of Biological Chemistry. 285: 37476-90. PMID 20837476 DOI: 10.1074/jbc.M110.123281  0.447
2010 Gramoun A, Azizi N, Sodek J, Heersche JN, Nakchbandi I, Manolson MF. Fibronectin inhibits osteoclastogenesis while enhancing osteoclast activity via nitric oxide and interleukin-1β-mediated signaling pathways. Journal of Cellular Biochemistry. 111: 1020-34. PMID 20672308 DOI: 10.1002/Jcb.22791  0.323
2010 Gramoun A, Goto T, Nordström T, Rotstein OD, Grinstein S, Heersche JN, Manolson MF. Bone matrix proteins and extracellular acidification: potential co-regulators of osteoclast morphology. Journal of Cellular Biochemistry. 111: 350-61. PMID 20506338 DOI: 10.1002/Jcb.22705  0.36
2010 Trebec-Reynolds DP, Voronov I, Heersche JN, Manolson MF. VEGF-A expression in osteoclasts is regulated by NF-kappaB induction of HIF-1alpha. Journal of Cellular Biochemistry. 110: 343-51. PMID 20432243 DOI: 10.1002/Jcb.22542  0.343
2009 Serrano EM, Ricofort RD, Zuo J, Ochotny N, Manolson MF, Holliday LS. Regulation of vacuolar H(+)-ATPase in microglia by RANKL. Biochemical and Biophysical Research Communications. 389: 193-7. PMID 19715671 DOI: 10.1016/J.Bbrc.2009.08.122  0.751
2009 Nilforoushan D, Gramoun A, Glogauer M, Manolson MF. Nitric oxide enhances osteoclastogenesis possibly by mediating cell fusion. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 21: 27-36. PMID 19389479 DOI: 10.1016/J.Niox.2009.04.002  0.318
2009 Ramachandran N, Munteanu I, Wang P, Aubourg P, Rilstone JJ, Israelian N, Naranian T, Paroutis P, Guo R, Ren ZP, Nishino I, Chabrol B, Pellissier JF, Minetti C, Udd B, ... ... Manolson MF, et al. VMA21 deficiency causes an autophagic myopathy by compromising V-ATPase activity and lysosomal acidification. Cell. 137: 235-46. PMID 19379691 DOI: 10.1016/J.Cell.2009.01.054  0.375
2008 Kartner N, Ochotny N, Yao Y, Aubin JE, Manolson MF. The V-ATPase a3 subunit: Potential therapeutic target for osteoporosis Bone. 43. DOI: 10.1016/J.Bone.2008.07.197  0.737
2007 Gramoun A, Shorey S, Bashutski JD, Dixon SJ, Sims SM, Heersche JN, Manolson MF. Effects of Vitaxin, a novel therapeutic in trial for metastatic bone tumors, on osteoclast functions in vitro. Journal of Cellular Biochemistry. 102: 341-52. PMID 17390341 DOI: 10.1002/Jcb.21296  0.354
2007 Trebec DP, Chandra D, Gramoun A, Li K, Heersche JN, Manolson MF. Increased expression of activating factors in large osteoclasts could explain their excessive activity in osteolytic diseases. Journal of Cellular Biochemistry. 101: 205-20. PMID 17216600 DOI: 10.1002/Jcb.21171  0.382
2006 Ochotny N, Van Vliet A, Chan N, Yao Y, Morel M, Kartner N, von Schroeder HP, Heersche JN, Manolson MF. Effects of human a3 and a4 mutations that result in osteopetrosis and distal renal tubular acidosis on yeast V-ATPase expression and activity. The Journal of Biological Chemistry. 281: 26102-11. PMID 16840787 DOI: 10.1074/Jbc.M601118200  0.754
2005 Voronov I, Heersche JN, Casper RF, Tenenbaum HC, Manolson MF. Inhibition of osteoclast differentiation by polycyclic aryl hydrocarbons is dependent on cell density and RANKL concentration. Biochemical Pharmacology. 70: 300-7. PMID 15919055 DOI: 10.1016/J.Bcp.2005.04.028  0.352
2004 Shorey S, Heersche JNM, Manolson MF. The relative contribution of cysteine proteinases and matrix metalloproteinases to the resorption process in osteoclasts derived from long bone and scapula Bone. 35: 909-917. PMID 15454098 DOI: 10.1016/J.Bone.2004.06.002  0.337
2004 Dixon S, Bashutski J, Rütz M, Goldberg H, Sims S, Gramoun A, Shorey S, Manolson M, Heersche J, Zhang H, Suzich J, Mao S. Arthritis Research & Therapy. 6: 23. DOI: 10.1186/Ar1358  0.354
2003 Manolson MF, Yu H, Chen W, Yao Y, Li K, Lees RL, Heersche JN. The a3 isoform of the 100-kDa V-ATPase subunit is highly but differentially expressed in large (>or=10 nuclei) and small (The Journal of Biological Chemistry. 278: 49271-8. PMID 14504271 DOI: 10.1074/Jbc.M309914200  0.548
2000 Landolt-Marticorena C, Williams KM, Correa J, Chen W, Manolson MF. Evidence That the NH2 Terminus of Vph1p, an Integral Subunit of the V0 Sector of the Yeast V-ATPase, Interacts Directly with the Vma1p and Vma13p Subunits of the V1Sector Journal of Biological Chemistry. 275: 15449-15457. PMID 10747882 DOI: 10.1074/Jbc.M000207200  0.436
1999 Plant PJ, Manolson MF, Grinstein S, Demaurex N. Alternative mechanisms of vacuolar acidification in H+-ATPase-deficient yeast Journal of Biological Chemistry. 274: 37270-37279. PMID 10601292 DOI: 10.1074/Jbc.274.52.37270  0.352
1999 Landolt-Marticorena C, Kahr WH, Zawarinski P, Correa J, Manolson MF. Substrate- and inhibitor-induced conformational changes in the yeast V-ATPase provide evidence for communication between the catalytic and proton-translocating sectors. Journal of Biological Chemistry. 274: 26057-26064. PMID 10473553 DOI: 10.1074/Jbc.274.37.26057  0.412
1998 Leng XH, Manolson MF, Forgac M. Function of the COOH-terminal domain of Vph1p in activity and assembly of the yeast V-ATPase Journal of Biological Chemistry. 273: 6717. PMID 9506970 DOI: 10.1074/Jbc.273.12.6717  0.415
1996 Leng XH, Manolson MF, Liu Q, Forgac M. Site-directed mutagenesis of the 100-kDA subunit (Vph1p) of the yeast vacuolar (H +)-ATPase Journal of Biological Chemistry. 271: 22487-22493. PMID 8798414 DOI: 10.1074/Jbc.271.37.22487  0.417
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