| Year |
Citation |
Score |
| 2021 |
Valls MD, Soldado M, Arasa J, Perez-Aso M, Williams AJ, Cronstein BN, Noguera MA, Terencio MC, Montesinos MC. Annexin A2-Mediated Plasminogen Activation in Endothelial Cells Contributes to the Proangiogenic Effect of Adenosine A Receptors. Frontiers in Pharmacology. 12: 654104. PMID 33986681 DOI: 10.3389/fphar.2021.654104 |
0.312 |
|
| 2020 |
Corciulo C, Castro CM, Coughlin T, Jacob S, Li Z, Fenyö D, Rifkin DB, Kennedy OD, Cronstein BN. Intraarticular injection of liposomal adenosine reduces cartilage damage in established murine and rat models of osteoarthritis. Scientific Reports. 10: 13477. PMID 32778777 DOI: 10.1038/S41598-020-68302-W |
0.32 |
|
| 2019 |
Corciulo C, Cronstein BN. Signaling of the Purinergic System in the Joint. Frontiers in Pharmacology. 10: 1591. PMID 32038258 DOI: 10.3389/Fphar.2019.01591 |
0.304 |
|
| 2019 |
Lopez CD, Coelho PG, Witek L, Torroni A, Greenberg MI, Cuadrado DL, Guarino AM, Bekisz JM, Cronstein BN, Flores RL. Regeneration of a Pediatric Alveolar Cleft Model Using Three-Dimensionally Printed Bioceramic Scaffolds and Osteogenic Agents: Comparison of Dipyridamole and rhBMP-2. Plastic and Reconstructive Surgery. 144: 358-370. PMID 31348344 DOI: 10.1097/Prs.0000000000005840 |
0.305 |
|
| 2019 |
Liu X, Corciulo C, Arabagian S, Ulman A, Cronstein BN. Adenosine-Functionalized Biodegradable PLA-b-PEG Nanoparticles Ameliorate Osteoarthritis in Rats. Scientific Reports. 9: 7430. PMID 31092864 DOI: 10.1038/S41598-019-43834-Y |
0.331 |
|
| 2019 |
Borhani S, Corciulo C, Larranaga-Vera A, Cronstein BN. Adenosine A receptor (A2AR) activation triggers Akt signaling and enhances nuclear localization of β-catenin in osteoblasts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900014R. PMID 30866652 DOI: 10.1096/Fj.201900014R |
0.31 |
|
| 2019 |
Conesa FM, Llamas-Granda P, Larrañaga-Vera A, Wilder T, Largo R, Herrero-Beaumont G, Cronstein B, Mediero A. Tenofovir causes bone loss via decreased bone formation and increased bone resorption, which can be counteracted by dipyridamole in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 30645771 DOI: 10.1002/Jbmr.3665 |
0.343 |
|
| 2019 |
Corciulo C, Castro C, Coughlin T, Jacob S, Fenyo D, Rifkin D, Kennedy O, Angle S, Cronstein B. A2A adenosine receptor stimulation regenerates cartilage in osteoarthritis animal model Osteoarthritis and Cartilage. 27: S174. DOI: 10.1016/J.Joca.2019.02.260 |
0.344 |
|
| 2018 |
Cerrone M, van Opbergen CJM, Malkani K, Irrera N, Zhang M, Van Veen TAB, Cronstein B, Delmar M. Blockade of the Adenosine 2A Receptor Mitigates the Cardiomyopathy Induced by Loss of Plakophilin-2 Expression. Frontiers in Physiology. 9: 1750. PMID 30568602 DOI: 10.3389/Fphys.2018.01750 |
0.418 |
|
| 2018 |
Lopez CD, Bekisz JM, Corciulo C, Mediero A, Coelho PG, Witek L, Flores RL, Cronstein BN. Local delivery of adenosine receptor agonists to promote bone regeneration and defect healing. Advanced Drug Delivery Reviews. PMID 29913176 DOI: 10.1016/J.Addr.2018.06.010 |
0.371 |
|
| 2018 |
Bekisz JM, Lopez CD, Corciulo C, Mediero A, Coelho PG, Witek L, Flores RL, Cronstein BN. The Role of Adenosine Receptor Activation in Attenuating Cartilaginous Inflammation. Inflammation. PMID 29656316 DOI: 10.1007/S10753-018-0781-Z |
0.397 |
|
| 2018 |
Haskó G, Antonioli L, Cronstein BN. Adenosine metabolism, immunity and joint health. Biochemical Pharmacology. PMID 29427624 DOI: 10.1016/J.Bcp.2018.02.002 |
0.38 |
|
| 2018 |
Mediero A, Wilder T, Shah L, Cronstein BN. Adenosine A2A receptor (A2AR) stimulation modulates expression of semaphorins 4D and 3A, regulators of bone homeostasis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201700217R. PMID 29394106 DOI: 10.1096/Fj.201700217R |
0.398 |
|
| 2017 |
Feig JL, Mediero A, Corciulo C, Liu H, Zhang J, Perez-Aso M, Picard L, Wilder T, Cronstein B. The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin. Plos One. 12: e0188135. PMID 29145453 DOI: 10.1371/Journal.Pone.0188135 |
0.323 |
|
| 2017 |
Corciulo C, Lendhey M, Wilder T, Schoen H, Cornelissen AS, Chang G, Kennedy OD, Cronstein BN. Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression. Nature Communications. 8: 15019. PMID 28492224 DOI: 10.1038/Ncomms15019 |
0.384 |
|
| 2017 |
Conesa F, Llamas P, Wilder T, Atencio P, Cabello A, Gόrgolas M, Cronstein B, Largo R, Herrero-Beaumont G, Mediero A. OP0186 Tenofovir, a nucleoside analog reverse transcriptase inhibitor for treatment of hiv, promotes osteoclast differentiation and bone lost in vivo in a mechanism depending on atp release and adenosine, and dipyridamole may be a useful treatment to revert the effects Annals of the Rheumatic Diseases. 76: 128-129. DOI: 10.1136/Annrheumdis-2017-Eular.3207 |
0.353 |
|
| 2016 |
Cronstein BN, Sitkovsky M. Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases. Nature Reviews. Rheumatology. PMID 27829671 DOI: 10.1038/Nrrheum.2016.178 |
0.417 |
|
| 2016 |
Shaikh G, Zhang J, Perez-Aso M, Mediero Munoz A, Cronstein B. Adenosine A2A Receptor Promotes Collagen Type III Synthesis Via β-Catenin Activation in Human Dermal Fibroblasts. British Journal of Pharmacology. PMID 27595240 DOI: 10.1111/Bph.13615 |
0.331 |
|
| 2016 |
Mediero A, Wilder T, Reddy VS, Cheng Q, Tovar N, Coelho PG, Witek L, Whatling C, Cronstein BN. Ticagrelor regulates osteoblast and osteoclast function and promotes bone formation in vivo via an adenosine-dependent mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27511945 DOI: 10.1096/Fj.201600616R |
0.343 |
|
| 2016 |
Mediero A, Wilder T, Ramkhelawon B, Moore KJ, Cronstein BN. Netrin-1 and its receptor Unc5b are novel targets for the treatment of inflammatory arthritis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27502509 DOI: 10.1096/Fj.201600615R |
0.343 |
|
| 2016 |
Strazzulla LC, Cronstein BN. Regulation of bone and cartilage by adenosine signaling. Purinergic Signalling. PMID 27473363 DOI: 10.1007/S11302-016-9527-2 |
0.336 |
|
| 2016 |
Corciulo C, Wilder T, Cronstein BN. Adenosine A2B receptors play an important role in bone homeostasis. Purinergic Signalling. PMID 27289226 DOI: 10.1007/S11302-016-9519-2 |
0.308 |
|
| 2016 |
Shaikh G, Cronstein B. Signaling pathways involving adenosine A2A and A2B receptors in wound healing and fibrosis Purinergic Signalling. 12: 191-197. PMID 26847815 DOI: 10.1007/S11302-016-9498-3 |
0.372 |
|
| 2016 |
Meltzer E, Mediero A, Whatling C, Berger JS, Cronstein B. Ticagrelor Modulates Proliferation in Multiple Myeloma Via P1 and P2 Receptor-Mediated Mechanisms Blood. 128: 5694-5694. DOI: 10.1182/Blood.V128.22.5694.5694 |
0.368 |
|
| 2015 |
Mediero A, Ramkhelawon B, Wilder T, Purdue PE, Goldring SR, Dewan MZ, Loomis C, Moore KJ, Cronstein BN. Netrin-1 is highly expressed and required in inflammatory infiltrates in wear particle-induced osteolysis. Annals of the Rheumatic Diseases. PMID 26452536 DOI: 10.1136/Annrheumdis-2015-207593 |
0.338 |
|
| 2015 |
Perez-Aso M, Montesinos MC, Mediero A, Wilder T, Schafer PH, Cronstein B. Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Arthritis Research & Therapy. 17: 249. PMID 26370839 DOI: 10.1186/S13075-015-0771-6 |
0.341 |
|
| 2015 |
Ferrari D, Gambari R, Idzko M, Müller T, Albanesi C, Pastore S, La Manna G, Robson SC, Cronstein B. Purinergic signaling in scarring. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26333425 DOI: 10.1096/Fj.15-274563 |
0.325 |
|
| 2015 |
Montesinos MC, Desai-Merchant A, Cronstein BN. Promotion of Wound Healing by an Agonist of Adenosine A2A Receptor Is Dependent on Tissue Plasminogen Activator. Inflammation. 38: 2036-41. PMID 25991438 DOI: 10.1007/S10753-015-0184-3 |
0.354 |
|
| 2015 |
Mediero A, Wilder T, Perez-Aso M, Cronstein BN. Direct or indirect stimulation of adenosine A2A receptors enhances bone regeneration as well as bone morphogenetic protein-2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1577-90. PMID 25573752 DOI: 10.1096/Fj.14-265066 |
0.323 |
|
| 2015 |
Mediero A, Perez-Aso M, Wilder T, Cronstein BN. Brief Report: Methotrexate Prevents Wear Particle-Induced Inflammatory Osteolysis in Mice Via Activation of Adenosine A2A Receptor. Arthritis & Rheumatology (Hoboken, N.J.). 67: 849-55. PMID 25533750 DOI: 10.1002/Art.38971 |
0.39 |
|
| 2015 |
Mediero A, Ramkhelawon B, Perez-Aso M, Moore KJ, Cronstein BN. Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 837-54. PMID 25483983 DOI: 10.1002/Jbmr.2421 |
0.347 |
|
| 2015 |
Mediero A, Mazumder A, Cronstein B. Netrin-1 and Its Receptors Unc5b and DCC May be Useful Targets for Preventing Multiple Myeloma Bone Lesions Blood. 126: 1815-1815. DOI: 10.1182/Blood.V126.23.1815.1815 |
0.335 |
|
| 2014 |
Mediero A, Perez-Aso M, Cronstein BN. Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4901-13. PMID 25122553 DOI: 10.1096/Fj.14-255703 |
0.346 |
|
| 2014 |
Perez-Aso M, Fernandez P, Mediero A, Chan ES, Cronstein BN. Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 802-12. PMID 24200882 DOI: 10.1096/Fj.13-241646 |
0.379 |
|
| 2013 |
Ouyang X, Ghani A, Malik A, Wilder T, Colegio OR, Flavell RA, Cronstein BN, Mehal WZ. Adenosine is required for sustained inflammasome activation via the A₂A receptor and the HIF-1α pathway. Nature Communications. 4: 2909. PMID 24352507 DOI: 10.1038/Ncomms3909 |
0.347 |
|
| 2013 |
He W, Wilder T, Cronstein BN. Rolofylline, an adenosine A1 receptor antagonist, inhibits osteoclast differentiation as an inverse agonist. British Journal of Pharmacology. 170: 1167-76. PMID 23962057 DOI: 10.1111/Bph.12342 |
0.42 |
|
| 2013 |
Perez-Aso M, Mediero A, Cronstein BN. Adenosine A2A receptor (A2AR) is a fine-tune regulator of the collagen1:collagen3 balance. Purinergic Signalling. 9: 573-83. PMID 23749290 DOI: 10.1007/S11302-013-9368-1 |
0.37 |
|
| 2013 |
He W, Mazumder A, Wilder T, Cronstein BN. Adenosine regulates bone metabolism via A1, A2A, and A2B receptors in bone marrow cells from normal humans and patients with multiple myeloma. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3446-54. PMID 23682121 DOI: 10.1096/Fj.13-231233 |
0.364 |
|
| 2013 |
Chan ES, Liu H, Fernandez P, Luna A, Perez-Aso M, Bujor AM, Trojanowska M, Cronstein BN. Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism. Arthritis Research & Therapy. 15: R58. PMID 23663495 DOI: 10.1186/Ar4229 |
0.391 |
|
| 2013 |
Mediero A, Perez-Aso M, Cronstein BN. Activation of adenosine A(2A) receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation. British Journal of Pharmacology. 169: 1372-88. PMID 23647065 DOI: 10.1111/Bph.12227 |
0.35 |
|
| 2013 |
Haskó G, Cronstein BN. Regulation of inflammation by adenosine. Frontiers in Immunology. 4: 85-85. PMID 23580000 DOI: 10.3389/Fimmu.2013.00085 |
0.407 |
|
| 2013 |
Mediero A, Cronstein BN. Adenosine and bone metabolism. Trends in Endocrinology and Metabolism: Tem. 24: 290-300. PMID 23499155 DOI: 10.1016/J.Tem.2013.02.001 |
0.327 |
|
| 2013 |
Perez-Aso M, Feig JL, Mediero A, Aránzazu M, Cronstein BN. Adenosine A2A receptor and TNF-α regulate the circadian machinery of the human monocytic THP-1 cells. Inflammation. 36: 152-62. PMID 22923002 DOI: 10.1007/S10753-012-9530-X |
0.339 |
|
| 2012 |
Perez-Aso M, Chiriboga L, Cronstein BN. Pharmacological blockade of adenosine A2A receptors diminishes scarring. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 4254-63. PMID 22767233 DOI: 10.1096/Fj.12-209627 |
0.373 |
|
| 2012 |
Mediero A, Frenkel SR, Wilder T, He W, Mazumder A, Cronstein BN. Adenosine A2A receptor activation prevents wear particle-induced osteolysis. Science Translational Medicine. 4: 135ra65. PMID 22623741 DOI: 10.1126/Scitranslmed.3003393 |
0.369 |
|
| 2012 |
Reiss AB, Cronstein BN. Regulation of foam cells by adenosine. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 879-86. PMID 22423040 DOI: 10.1161/Atvbaha.111.226878 |
0.44 |
|
| 2012 |
He W, Cronstein BN. Adenosine A1 receptor regulates osteoclast formation by altering TRAF6/TAK1 signaling Purinergic Signalling. 8: 327-337. PMID 22311477 DOI: 10.1007/S11302-012-9292-9 |
0.402 |
|
| 2012 |
Mediero A, Kara FM, Wilder T, Cronstein BN. Adenosine A(2A) receptor ligation inhibits osteoclast formation. The American Journal of Pathology. 180: 775-86. PMID 22138579 DOI: 10.1016/J.Ajpath.2011.10.017 |
0.413 |
|
| 2012 |
Williams AJ, Cronstein BN. The effect of A(2A) adenosine receptor activation on C-C chemokine receptor 7 expression in human THP1 macrophages during inflammation. Inflammation. 35: 614-22. PMID 21739164 DOI: 10.1007/S10753-011-9353-1 |
0.428 |
|
| 2012 |
Bingham TC, Parathath S, Tian H, Reiss A, Chan E, Fisher EA, Cronstein BN. Cholesterol 27-hydroxylase but not apolipoprotein apoE contributes to A2A adenosine receptor stimulated reverse cholesterol transport. Inflammation. 35: 49-57. PMID 21258856 DOI: 10.1007/S10753-010-9288-Y |
0.74 |
|
| 2012 |
He W, Park J, Mazumder A, Cronstein B. Adenosine Regulates Bone Metabolism Via A1, A2A and A2B Receptors in Bone Marrow Cells From Normal and Patients with Multiple Myeloma Blood. 120: 4977-4977. DOI: 10.1182/Blood.V120.21.4977.4977 |
0.402 |
|
| 2012 |
Perez-Aso M, Feig JL, Mediero A, Cronstein BN. Erratum to: Adenosine A2A Inflammation. 36: 163-163. DOI: 10.1007/S10753-012-9553-3 |
0.321 |
|
| 2011 |
Cronstein BN. Adenosine receptors and fibrosis: a translational review. F1000 Biology Reports. 3: 21. PMID 22003368 DOI: 10.3410/B3-21 |
0.369 |
|
| 2011 |
He W, Cronstein B. The roles of adenosine and adenosine receptors in bone remodeling. Frontiers in Bioscience (Elite Edition). 3: 888-95. PMID 21622100 DOI: 10.2741/E297 |
0.401 |
|
| 2011 |
Haskó G, Cronstein B. Methylxanthines and Inflammatory Cells Handbook of Experimental Pharmacology. 200: 457-468. PMID 20859808 DOI: 10.1007/978-3-642-13443-2_18 |
0.404 |
|
| 2010 |
Himer L, Csóka B, Selmeczy Z, Koscsó B, Pócza T, Pacher P, Németh ZH, Deitch EA, Vizi ES, Cronstein BN, Haskó G. Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2631-40. PMID 20371613 DOI: 10.1096/Fj.10-155192 |
0.411 |
|
| 2010 |
Chan ES, Cronstein BN. Methotrexate--how does it really work? Nature Reviews. Rheumatology. 6: 175-8. PMID 20197777 DOI: 10.1038/Nrrheum.2010.5 |
0.345 |
|
| 2010 |
Kara FM, Chitu V, Sloane J, Axelrod M, Fredholm BB, Stanley ER, Cronstein BN. Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2325-33. PMID 20181934 DOI: 10.1096/Fj.09-147447 |
0.331 |
|
| 2010 |
Kara FM, Doty SB, Boskey A, Goldring S, Zaidi M, Fredholm BB, Cronstein BN. Adenosine A(1) receptors regulate bone resorption in mice: adenosine A(1) receptor blockade or deletion increases bone density and prevents ovariectomy-induced bone loss in adenosine A(1) receptor-knockout mice. Arthritis and Rheumatism. 62: 534-41. PMID 20112380 DOI: 10.1002/Art.27219 |
0.348 |
|
| 2010 |
Bingham TC, Fisher EA, Parathath S, Reiss AB, Chan ES, Cronstein BN. A2A adenosine receptor stimulation decreases foam cell formation by enhancing ABCA1-dependent cholesterol efflux. Journal of Leukocyte Biology. 87: 683-90. PMID 20089670 DOI: 10.1189/Jlb.0709513 |
0.73 |
|
| 2010 |
Chan ES, Cronstein BN. Adenosine in fibrosis. Modern Rheumatology / the Japan Rheumatism Association. 20: 114-22. PMID 19949965 DOI: 10.1007/S10165-009-0251-4 |
0.328 |
|
| 2010 |
Reiss AB, Anwar K, Merrill JT, Chan ES, Awadallah NW, Cronstein BN, Michael Belmont H, Belilos E, Rosenblum G, Belostocki K, Bonetti L, Hasneen K, Carsons SE. Plasma from systemic lupus patients compromises cholesterol homeostasis: a potential mechanism linking autoimmunity to atherosclerotic cardiovascular disease. Rheumatology International. 30: 591-8. PMID 19547978 DOI: 10.1007/S00296-009-1020-6 |
0.309 |
|
| 2009 |
Feoktistov I, Biaggioni I, Cronstein BN. Adenosine receptors in wound healing, fibrosis and angiogenesis. Handbook of Experimental Pharmacology. 383-97. PMID 19639289 DOI: 10.1007/978-3-540-89615-9_13 |
0.382 |
|
| 2009 |
Peng Z, Borea PA, Varani K, Wilder T, Yee H, Chiriboga L, Blackburn MR, Azzena G, Resta G, Cronstein BN. Adenosine signaling contributes to ethanol-induced fatty liver in mice. The Journal of Clinical Investigation. 119: 582-94. PMID 19221436 DOI: 10.1172/Jci37409 |
0.34 |
|
| 2009 |
Reiss AB, Wan DW, Anwar K, Merrill JT, Wirkowski PA, Shah N, Cronstein BN, Chan ES, Carsons SE. Enhanced CD36 scavenger receptor expression in THP-1 human monocytes in the presence of lupus plasma: linking autoimmunity and atherosclerosis. Experimental Biology and Medicine (Maywood, N.J.). 234: 354-60. PMID 19144874 DOI: 10.3181/0806-Bc-194 |
0.31 |
|
| 2009 |
Katebi M, Soleimani M, Cronstein BN. Adenosine A2A receptors play an active role in mouse bone marrow-derived mesenchymal stem cell development. Journal of Leukocyte Biology. 85: 438-44. PMID 19056861 DOI: 10.1189/Jlb.0908520 |
0.377 |
|
| 2009 |
Valls MD, Cronstein BN, Montesinos MC. Adenosine receptor agonists for promotion of dermal wound healing. Biochemical Pharmacology. 77: 1117-24. PMID 19041853 DOI: 10.1016/J.Bcp.2008.11.002 |
0.324 |
|
| 2008 |
Reiss AB, Carsons SE, Anwar K, Rao S, Edelman SD, Zhang H, Fernandez P, Cronstein BN, Chan ES. Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages. Arthritis and Rheumatism. 58: 3675-83. PMID 19035488 DOI: 10.1002/Art.24040 |
0.322 |
|
| 2008 |
Haskó G, Linden J, Cronstein B, Pacher P. Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nature Reviews. Drug Discovery. 7: 759-70. PMID 18758473 DOI: 10.1038/Nrd2638 |
0.422 |
|
| 2008 |
Katebi M, Fernandez P, Chan ES, Cronstein BN. Adenosine A2A receptor blockade or deletion diminishes fibrocyte accumulation in the skin in a murine model of scleroderma, bleomycin-induced fibrosis. Inflammation. 31: 299-303. PMID 18709547 DOI: 10.1007/S10753-008-9078-Y |
0.389 |
|
| 2008 |
Peng Z, Fernandez P, Wilder T, Yee H, Chiriboga L, Chan ES, Cronstein BN. Ecto-5'-nucleotidase (CD73)-mediated extracellular adenosine production plays a critical role in hepatic fibrosis. Nucleosides, Nucleotides & Nucleic Acids. 27: 821-4. PMID 18600546 DOI: 10.1080/15257770802146403 |
0.339 |
|
| 2008 |
Fernández P, Trzaska S, Wilder T, Chiriboga L, Blackburn MR, Cronstein BN, Chan ES. Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine. The American Journal of Pathology. 172: 1675-82. PMID 18467695 DOI: 10.2353/Ajpath.2008.070952 |
0.395 |
|
| 2008 |
Peng Z, Fernandez P, Wilder T, Yee H, Chiriboga L, Chan ES, Cronstein BN. Ecto-5'-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2263-72. PMID 18263696 DOI: 10.1096/Fj.07-100685 |
0.328 |
|
| 2007 |
Chan ESL, Fernandez P, Cronstein BN. Adenosine in inflammatory joint diseases. Purinergic Signalling. 3: 145-152. PMID 18404428 DOI: 10.1007/S11302-006-9046-7 |
0.329 |
|
| 2007 |
Macedo L, Pinhal-Enfield G, Alshits V, Elson G, Cronstein BN, Leibovich SJ. Wound healing is impaired in MyD88-deficient mice: a role for MyD88 in the regulation of wound healing by adenosine A2A receptors. The American Journal of Pathology. 171: 1774-88. PMID 17974599 DOI: 10.2353/Ajpath.2007.061048 |
0.357 |
|
| 2007 |
Che J, Chan ES, Cronstein BN. Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway. Molecular Pharmacology. 72: 1626-36. PMID 17872970 DOI: 10.1124/Mol.107.038760 |
0.38 |
|
| 2007 |
Montesinos MC, Takedachi M, Thompson LF, Wilder TF, Fernández P, Cronstein BN. The antiinflammatory mechanism of methotrexate depends on extracellular conversion of adenine nucleotides to adenosine by ecto-5'-nucleotidase: findings in a study of ecto-5'-nucleotidase gene-deficient mice. Arthritis and Rheumatism. 56: 1440-5. PMID 17469101 DOI: 10.1002/Art.22643 |
0.314 |
|
| 2007 |
Németh ZH, Bleich D, Csóka B, Pacher P, Mabley JG, Himer L, Vizi ES, Deitch EA, Szabó C, Cronstein BN, Haskó G. Adenosine receptor activation ameliorates type 1 diabetes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2379-88. PMID 17405852 DOI: 10.1096/Fj.07-8213Com |
0.375 |
|
| 2007 |
Cronstein BN. Adenosine and Inflammation Immunology‚ Endocrine & Metabolic Agents in Medicinal Chemistry. 7: 280-285. DOI: 10.2174/187152207781369841 |
0.353 |
|
| 2006 |
Chan ES, Fernandez P, Merchant AA, Montesinos MC, Trzaska S, Desai A, Tung CF, Khoa DN, Pillinger MH, Reiss AB, Tomic-Canic M, Chen JF, Schwarzschild MA, Cronstein BN. Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma. Arthritis and Rheumatism. 54: 2632-42. PMID 16871530 DOI: 10.1002/Art.21974 |
0.416 |
|
| 2006 |
Levy O, Coughlin M, Cronstein BN, Roy RM, Desai A, Wessels MR. The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn. Journal of Immunology (Baltimore, Md. : 1950). 177: 1956-66. PMID 16849509 DOI: 10.4049/Jimmunol.177.3.1956 |
0.337 |
|
| 2006 |
Cronstein BN, Terkeltaub R. The inflammatory process of gout and its treatment. Arthritis Research & Therapy. 8: S3. PMID 16820042 DOI: 10.1186/Ar1908 |
0.352 |
|
| 2006 |
Bours MJL, Swennen ELR, Virgilio FD, Cronstein BN, Dagnelie PC. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation Pharmacology & Therapeutics. 112: 358-404. PMID 16784779 DOI: 10.1016/J.Pharmthera.2005.04.013 |
0.333 |
|
| 2006 |
Chan ES, Montesinos MC, Fernandez P, Desai A, Delano DL, Yee H, Reiss AB, Pillinger MH, Chen JF, Schwarzschild MA, Friedman SL, Cronstein BN. Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis. British Journal of Pharmacology. 148: 1144-55. PMID 16783407 DOI: 10.1038/Sj.Bjp.0706812 |
0.405 |
|
| 2006 |
Montesinos MC, Desai A, Cronstein BN. Suppression of inflammation by low-dose methotrexate is mediated by adenosine A2A receptor but not A3 receptor activation in thioglycollate-induced peritonitis. Arthritis Research & Therapy. 8: R53. PMID 16519795 DOI: 10.1186/Ar1914 |
0.386 |
|
| 2006 |
Khoa ND, Postow M, Danielsson J, Cronstein BN. Tumor necrosis factor-alpha prevents desensitization of Galphas-coupled receptors by regulating GRK2 association with the plasma membrane. Molecular Pharmacology. 69: 1311-9. PMID 16385076 DOI: 10.1124/Mol.105.016857 |
0.314 |
|
| 2005 |
Cronstein BN. Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis. Pharmacological Reviews. 57: 163-72. PMID 15914465 DOI: 10.1124/Pr.57.2.3 |
0.339 |
|
| 2005 |
Desai A, Victor-Vega C, Gadangi S, Montesinos MC, Chu CC, Cronstein BN. Adenosine A2A receptor stimulation increases angiogenesis by down-regulating production of the antiangiogenic matrix protein thrombospondin 1. Molecular Pharmacology. 67: 1406-13. PMID 15673602 DOI: 10.1124/Mol.104.007807 |
0.418 |
|
| 2004 |
Reiss AB, Rahman MM, Chan ES, Montesinos MC, Awadallah NW, Cronstein BN. Adenosine A2A receptor occupancy stimulates expression of proteins involved in reverse cholesterol transport and inhibits foam cell formation in macrophages. Journal of Leukocyte Biology. 76: 727-34. PMID 15197231 DOI: 10.1189/Jlb.0204107 |
0.411 |
|
| 2004 |
Montesinos MC, Shaw JP, Yee H, Shamamian P, Cronstein BN. Adenosine A(2A) receptor activation promotes wound neovascularization by stimulating angiogenesis and vasculogenesis. The American Journal of Pathology. 164: 1887-92. PMID 15161625 DOI: 10.1016/S0002-9440(10)63749-2 |
0.396 |
|
| 2004 |
Cronstein BN. Adenosine receptors and wound healing. Thescientificworldjournal. 4: 1-8. PMID 14755098 DOI: 10.1100/Tsw.2004.1 |
0.376 |
|
| 2004 |
Haskó G, Cronstein BN. Adenosine: an endogenous regulator of innate immunity. Trends in Immunology. 25: 33-9. PMID 14698282 DOI: 10.1016/J.It.2003.11.003 |
0.341 |
|
| 2003 |
Nguyen DK, Montesinos MC, Williams AJ, Kelly M, Cronstein BN. Th1 cytokines regulate adenosine receptors and their downstream signaling elements in human microvascular endothelial cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 3991-8. PMID 14530318 DOI: 10.4049/Jimmunol.171.8.3991 |
0.413 |
|
| 2003 |
Montesinos MC, Desai A, Delano D, Chen JF, Fink JS, Jacobson MA, Cronstein BN. Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68. Arthritis and Rheumatism. 48: 240-7. PMID 12528125 DOI: 10.1002/Art.10712 |
0.414 |
|
| 2002 |
Weissmann G, Montesinos MC, Pillinger M, Cronstein BN. Non-prostaglandin effects of aspirin III and salicylate: inhibition of integrin-dependent human neutrophil aggregation and inflammation in COX 2- and NF kappa B (P105)-knockout mice. Advances in Experimental Medicine and Biology. 507: 571-7. PMID 12664642 DOI: 10.1007/978-1-4615-0193-0_87 |
0.334 |
|
| 2002 |
Chan ES, Cronstein BN. Molecular action of methotrexate in inflammatory diseases. Arthritis Research. 4: 266-73. PMID 12106498 DOI: 10.1186/Ar419 |
0.379 |
|
| 2002 |
Leibovich SJ, Chen JF, Pinhal-Enfield G, Belem PC, Elson G, Rosania A, Ramanathan M, Montesinos C, Jacobson M, Schwarzschild MA, Fink JS, Cronstein B. Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin. The American Journal of Pathology. 160: 2231-44. PMID 12057925 DOI: 10.1016/S0002-9440(10)61170-4 |
0.392 |
|
| 2002 |
Montesinos MC, Desai A, Chen JF, Yee H, Schwarzschild MA, Fink JS, Cronstein BN. Adenosine promotes wound healing and mediates angiogenesis in response to tissue injury via occupancy of A(2A) receptors. The American Journal of Pathology. 160: 2009-18. PMID 12057906 DOI: 10.1016/S0002-9440(10)61151-0 |
0.395 |
|
| 2002 |
Victor-Vega C, Desai A, Montesinos MC, Cronstein BN. Adenosine A2A receptor agonists promote more rapid wound healing than recombinant human platelet-derived growth factor (Becaplermin gel). Inflammation. 26: 19-24. PMID 11936752 DOI: 10.1023/A:1014417728325 |
0.34 |
|
| 2001 |
Khoa ND, Montesinos MC, Reiss AB, Delano D, Awadallah N, Cronstein BN. Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 4026-32. PMID 11564822 DOI: 10.4049/Jimmunol.167.7.4026 |
0.405 |
|
| 2001 |
Montesinos MC, Cronstein BN. Role of P1 Receptors in Inflammation Handbook of Experimental Pharmacology. 151: 303-321. DOI: 10.1007/978-3-642-56921-0_9 |
0.358 |
|
| 2001 |
Cronstein BN, Montesinos MC, Chan E. Adenosine mediates the antiinflammatory effects of methotrexate as well as its toxicities Drug Development Research. 52: 394-396. DOI: 10.1002/Ddr.1139 |
0.423 |
|
| 2000 |
Montesinos MC, Yap JS, Desai A, Posadas I, McCrary CT, Cronstein BN. Reversal of the antiinflammatory effects of methotrexate by the nonselective adenosine receptor antagonists theophylline and caffeine: evidence that the antiinflammatory effects of methotrexate are mediated via multiple adenosine receptors in rat adjuvant arthritis. Arthritis and Rheumatism. 43: 656-63. PMID 10728760 DOI: 10.1002/1529-0131(200003)43:3<656::Aid-Anr23>3.0.Co;2-H |
0.394 |
|
| 1999 |
Cronstein BN, Montesinos MC, Weissmann G. Sites of action for future therapy: an adenosine-dependent mechanism by which aspirin retains its antiinflammatory activity in cyclooxygenase-2 and NFkappaB knockout mice. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 7: 361-3. PMID 10419767 DOI: 10.1053/Joca.1998.0236 |
0.378 |
|
| 1999 |
Cronstein BN, Montesinos MC, Weissmann G. Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFkappaB. Proceedings of the National Academy of Sciences of the United States of America. 96: 6377-81. PMID 10339595 DOI: 10.1073/Pnas.96.11.6377 |
0.401 |
|
| 1999 |
Weissmann G, Montesinos MC, Cronstein BN. Salicylates, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 (p50) of nuclear factor Kb (NFκb) Prostaglandins & Other Lipid Mediators. 59: 2. DOI: 10.1016/S0090-6980(99)90237-X |
0.315 |
|
| 1998 |
Morabito L, Montesinos MC, Schreibman DM, Balter L, Thompson LF, Resta R, Carlin G, Huie MA, Cronstein BN. Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides. The Journal of Clinical Investigation. 101: 295-300. PMID 9435300 DOI: 10.1172/Jci1554 |
0.416 |
|
| 1997 |
Montesinos MC, Gadangi P, Longaker M, Sung J, Levine J, Nilsen D, Reibman J, Li M, Jiang CK, Hirschhorn R, Recht PA, Ostad E, Levin RI, Cronstein BN. Wound healing is accelerated by agonists of adenosine A2 (G alpha s-linked) receptors. The Journal of Experimental Medicine. 186: 1615-20. PMID 9348321 DOI: 10.1084/Jem.186.9.1615 |
0.321 |
|
| 1997 |
Merrill JT, Shen C, Schreibman D, Coffey D, Zakharenko O, Fisher R, Lahita RG, Salmon J, Cronstein BN. Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes. A mechanism for methotrexate‐induced nodulosis in rheumatoid arthritis Arthritis & Rheumatism. 40: 1308-1315. PMID 9214432 DOI: 10.1002/1529-0131(199707)40:7<1308::Aid-Art16>3.0.Co;2-M |
0.41 |
|
| 1997 |
Merrill JT, Diakolios C, Goodman S, Dinu A, Shen C, Lahita RG, Cronstein BN, Mitnick H, Bauer B, Paget S, Greisman S. Inhibition of methotrexate-induced rheumatoid nodulosis by colchicine: evidence from an in vitro model and regression in 7 of 14 patients. Jcr-Journal of Clinical Rheumatology. 3: 328-333. DOI: 10.1097/00124743-199712000-00005 |
0.4 |
|
| 1996 |
Wisniewski H, Naime D, Hua JC, Vilcek J, Cronstein BN. TSG-6, a glycoprotein associated with arthritis, and its ligand hyaluronan exert opposite effects in a murine model of inflammation PflüGers Archiv: European Journal of Physiology. 431. PMID 8739346 DOI: 10.1007/Bf02346350 |
0.341 |
|
| 1996 |
Revan S, Montesinos MC, Naime D, Landau S, Cronstein BN. Adenosine A2 receptor occupancy regulates stimulated neutrophil function via activation of a serine/threonine protein phosphatase. The Journal of Biological Chemistry. 271: 17114-8. PMID 8663342 DOI: 10.1074/Jbc.271.29.17114 |
0.398 |
|
| 1996 |
Cronstein BN, Bouma MG, Becker BF. Purinergic mechanisms in inflammation Drug Development Research. 39: 426-435. DOI: 10.1002/(Sici)1098-2299(199611/12)39:3/4<426::Aid-Ddr24>3.0.Co;2-Y |
0.427 |
|
| 1995 |
Cronstein BN, Naime D, Firestein G. The antiinflammatory effects of an adenosine kinase inhibitor are mediated by adenosine. Arthritis & Rheumatism. 38: 1040-1045. PMID 7662029 DOI: 10.1002/Art.1780380804 |
0.402 |
|
| 1995 |
Cronstein BN, Naime D, Ostad E. The Antiinflammatory Effects of Methotrexate are Mediated by Adenosine Advances in Experimental Medicine and Biology. 370: 411-416. PMID 7660940 DOI: 10.1007/978-1-4615-2584-4_89 |
0.401 |
|
| 1995 |
Cronstein BN, Molad Y, Reibman J, Balakhane E, Levin RI, Weissmann G. Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils. The Journal of Clinical Investigation. 96: 994-1002. PMID 7543498 DOI: 10.1172/Jci118147 |
0.327 |
|
| 1994 |
Cronstein BN. Adenosine, an endogenous anti-inflammatory agent Journal of Applied Physiology. 76: 5-13. PMID 8175547 DOI: 10.1152/Jappl.1994.76.1.5 |
0.395 |
|
| 1994 |
Cronstein BN, Van de Stouwe M, Druska L, Levin RI, Weissmann G. Nonsteroidal antiinflammatory agents inhibit stimulated neutrophil adhesion to endothelium: adenosine dependent and independent mechanisms. Inflammation. 18: 323-35. PMID 8088928 DOI: 10.1007/Bf01534273 |
0.379 |
|
| 1994 |
Cronstein BN. Adhesion molecules in the pathogenesis of rheumatoid arthritis. Current Opinion in Rheumatology. 6: 300-304. PMID 8060766 DOI: 10.1097/00002281-199405000-00010 |
0.32 |
|
| 1994 |
Molad Y, Haines KA, Anderson DC, Buyon JP, Cronstein BN. Immunocomplexes stimulate different signalling events to chemoattractants in the neutrophil and regulate L-selectin and beta 2-integrin expression differently. Biochemical Journal. 299: 881-887. PMID 7514872 DOI: 10.1042/Bj2990881 |
0.355 |
|
| 1993 |
Cronstein BN, Weissmann G. The adhesion molecules of inflammation. Arthritis and Rheumatism. 36: 147-57. PMID 8431203 DOI: 10.1002/Art.1780360204 |
0.313 |
|
| 1993 |
Cronstein BN, Naime D, Ostad E. The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation. Journal of Clinical Investigation. 92: 2675-2682. PMID 8254024 DOI: 10.1172/Jci116884 |
0.405 |
|
| 1992 |
Kolasinski SL, Haines KA, Siegel EL, Cronstein BN, Abramson SB. Neuropeptides and inflammation. A somatostatin analog as a selective antagonist of neutrophil activation by substance P Arthritis & Rheumatism. 35: 369-375. PMID 1373619 DOI: 10.1002/Art.1780350402 |
0.329 |
|
| 1992 |
Cronstein BN, Haines KA. Stimulus-response uncoupling in the neutrophil. Adenosine A2-receptor occupancy inhibits the sustained, but not the early, events of stimulus transduction in human neutrophils by a mechanism independent of actin-filament formation. Biochemical Journal. 281: 631-635. PMID 1311169 DOI: 10.1042/Bj2810631 |
0.411 |
|
| 1992 |
Cronstein BN, Kimmel SC, Levin RI, Martiniuk F, Weissmann G. A mechanism for the antiinflammatory effects of corticosteroids: The glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule Proceedings of the National Academy of Sciences of the United States of America. 89: 9991-9995. PMID 1279685 DOI: 10.1097/00005176-199307000-00022 |
0.381 |
|
| 1992 |
Cronstein B, Haines K, Kolasinski S, Reibman J. Occupancy of G alpha s-linked receptors uncouples chemoattractant receptors from their stimulus-transduction mechanisms in the neutrophil Blood. 80: 1052-1057. DOI: 10.1182/Blood.V80.4.1052.1052 |
0.358 |
|
| 1991 |
Cronstein BN, Eberle MA, Gruber HE, Levin RI. Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 2441-2445. PMID 2006182 DOI: 10.1073/Pnas.88.6.2441 |
0.358 |
|
| 1990 |
Cronstein BN, Daguma L, Nichols D, Hutchison AJ, Williams M. The adenosine/neutrophil paradox resolved: human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively. Journal of Clinical Investigation. 85: 1150-1157. PMID 2156895 DOI: 10.1172/Jci114547 |
0.387 |
|
| 1989 |
Cronstein BN, Rose FR, Pugliese C. Adenosine, a cytoprotective autocoid: effects of adenosine on neutrophil plasma membrane viscosity and chemoattractant receptor display. Biochimica Et Biophysica Acta. 987: 176-80. PMID 2574995 DOI: 10.1016/0005-2736(89)90541-5 |
0.375 |
|
| 1988 |
Cronstein BN, Kramer SB, Rosenstein ED, Korchak HM, Weissmann G, Hirschhorn R. Occupancy of adenosine receptors raises cyclic AMP alone and in synergy with occupancy of chemoattractant receptors and inhibits membrane depolarization. The Biochemical Journal. 252: 709-15. PMID 2844154 DOI: 10.1042/Bj2520709 |
0.399 |
|
| 1988 |
Rose FR, Hirschhorn R, Weissmann G, Cronstein BN. Adenosine promotes neutrophil chemotaxis. The Journal of Experimental Medicine. 167: 1186-94. PMID 2832507 DOI: 10.1084/Jem.167.3.1186 |
0.429 |
|
| 1987 |
Cronstein BN, Kubersky SM, Weissmann G, Hirschhorn R. Engagement of adenosine receptors inhibits hydrogen peroxide (H2O2-) release by activated human neutrophils. Clinical Immunology and Immunopathology. 42: 76-85. PMID 3024892 DOI: 10.1016/0090-1229(87)90174-7 |
0.381 |
|
| 1986 |
Cronstein BN, Levin RI, Belanoff J, Weissmann G, Hirschhorn R. Adenosine: An Endogenous Inhibitor of Neutrophil-Mediated Injury to Endothelial Cells Journal of Clinical Investigation. 78: 760-770. PMID 3745437 DOI: 10.1172/Jci112638 |
0.364 |
|
| 1985 |
Cronstein BN, Kramer SB, Rosenstein ED, Weissmann G, Hirschhorn R. Adenosine modulates the generation of superoxide anion by stimulated human neutrophils via interaction with a specific cell surface receptor. Annals of the New York Academy of Sciences. 451: 291-301. PMID 3000259 DOI: 10.1111/J.1749-6632.1985.Tb27120.X |
0.355 |
|
| 1984 |
Cronstein BN, Kramer SB, Weissmann G, Hirschhorn R. Adenosine deaminase is not required for the generation of superoxide anion. Clinical Immunology and Immunopathology. 30: 495-9. PMID 6321074 DOI: 10.1016/0090-1229(84)90035-7 |
0.337 |
|
| 1983 |
Cronstein BN, Kramer SB, Weissmann G, Hirschhorn R. Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. The Journal of Experimental Medicine. 158: 1160-77. PMID 6311934 DOI: 10.1084/Jem.158.4.1160 |
0.383 |
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