Stefan Duensing - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Virology Biology, Molecular Biology

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Li J, Pohl L, Schüler J, Korzeniewski N, Reimold P, Kaczorowski A, Hou W, Zschäbitz S, Nientiedt C, Jäger D, Hohenfellner M, Duensing A, Duensing S. Targeting the Proteasome in Advanced Renal Cell Carcinoma: Complexity and Limitations of Patient-Individualized Preclinical Drug Discovery. Biomedicines. 9. PMID 34072926 DOI: 10.3390/biomedicines9060627  0.705
2019 Tapia-Laliena MÁ, Korzeniewski N, Peña-Llopis S, Scholl C, Fröhling S, Hohenfellner M, Duensing A, Duensing S. Cullin 5 is a novel candidate tumor suppressor in renal cell carcinoma involved in the maintenance of genome stability. Oncogenesis. 8: 4. PMID 30631037 DOI: 10.1038/s41389-018-0110-2  0.754
2017 Heller M, Prigge ES, Kaczorowski A, von Knebel Doeberitz M, Hohenfellner M, Duensing S. APOBEC3A Expression in Penile Squamous Cell Carcinoma. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. PMID 29166639 DOI: 10.1159/000479007  0.425
2016 Hoefflin R, Lahrmann B, Warsow G, Hübschmann D, Spath C, Walter B, Chen X, Hofer L, Macher-Goeppinger S, Tolstov Y, Korzeniewski N, Duensing A, Grüllich C, Jäger D, Perner S, ... ... Duensing S, et al. Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity. Nature Communications. 7: ncomms11845. PMID 27291893 DOI: 10.1038/Ncomms11845  0.72
2015 Mang J, Korzeniewski N, Dietrich D, Sailer V, Tolstov Y, Searcy S, von Hardenberg J, Perner S, Kristiansen G, Marx A, Roth W, Herpel E, Grüllich C, Popeneciu V, Pahernik S, ... ... Duensing S, et al. Prognostic Significance and Functional Role of CEP57 in Prostate Cancer. Translational Oncology. 8: 487-96. PMID 26692530 DOI: 10.1016/J.Tranon.2015.11.004  0.755
2015 Korzeniewski N, Tosev G, Pahernik S, Hadaschik B, Hohenfellner M, Duensing S. Identification of cell-free microRNAs in the urine of patients with prostate cancer. Urologic Oncology. 33: 16.e17-22. PMID 25445383 DOI: 10.1016/J.Urolonc.2014.09.015  0.724
2015 Schneider M, Korzeniewski N, Merkle K, Schüler J, Grüllich C, Hadaschik B, Hohenfellner M, Duensing S. The tyrosine kinase inhibitor nilotinib has antineoplastic activity in prostate cancer cells but up-regulates the ERK survival signal-Implications for targeted therapies. Urologic Oncology. 33: 72.e1-7. PMID 24996772 DOI: 10.1016/J.Urolonc.2014.06.001  0.738
2014 Georgi B, Korzeniewski N, Hadaschik B, Grüllich C, Roth W, Sültmann H, Pahernik S, Hohenfellner M, Duensing S. Evolving therapeutic concepts in prostate cancer based on genome-wide analyses (review). International Journal of Oncology. 45: 1337-44. PMID 25070358 DOI: 10.3892/Ijo.2014.2567  0.727
2014 Tapia-Laliena MA, Korzeniewski N, Hohenfellner M, Duensing S. High-risk prostate cancer: a disease of genomic instability. Urologic Oncology. 32: 1101-7. PMID 24931269 DOI: 10.1016/J.Urolonc.2014.02.005  0.732
2014 Schneider M, Schüler J, Höfflin R, Korzeniewski N, Grüllich C, Roth W, Teber D, Hadaschik B, Pahernik S, Hohenfellner M, Duensing S. Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma. Urologic Oncology. 32: 877-84. PMID 24929890 DOI: 10.1016/J.Urolonc.2014.03.011  0.726
2014 Tolstov Y, Hadaschik B, Pahernik S, Hohenfellner M, Duensing S. Human papillomaviruses in urological malignancies: a critical assessment. Urologic Oncology. 32: 46.e19-27. PMID 24140249 DOI: 10.1016/j.urolonc.2013.06.012  0.369
2013 Cuevas R, Korzeniewski N, Tolstov Y, Hohenfellner M, Duensing S. FGF-2 disrupts mitotic stability in prostate cancer through the intracellular trafficking protein CEP57. Cancer Research. 73: 1400-10. PMID 23243019 DOI: 10.1158/0008-5472.Can-12-1857  0.751
2013 Korzeniewski N, Hohenfellner M, Duensing S. The centrosome as potential target for cancer therapy and prevention. Expert Opinion On Therapeutic Targets. 17: 43-52. PMID 23062185 DOI: 10.1517/14728222.2013.731396  0.749
2012 Korzeniewski N, Hohenfellner M, Duensing S. CAND1 promotes PLK4-mediated centriole overduplication and is frequently disrupted in prostate cancer. Neoplasia (New York, N.Y.). 14: 799-806. PMID 23019411 DOI: 10.1593/Neo.12580  0.762
2012 Li J, Kim S, Kobayashi T, Liang FX, Korzeniewski N, Duensing S, Dynlacht BD. Neurl4, a novel daughter centriole protein, prevents formation of ectopic microtubule organizing centres. Embo Reports. 13: 547-53. PMID 22441691 DOI: 10.1038/Embor.2012.40  0.707
2011 Korzeniewski N, Treat B, Duensing S. The HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of Polo-like kinase 4 expression. Molecular Cancer. 10: 61. PMID 21609466 DOI: 10.1186/1476-4598-10-61  0.794
2011 Korzeniewski N, Spardy N, Duensing A, Duensing S. Genomic instability and cancer: lessons learned from human papillomaviruses. Cancer Letters. 305: 113-22. PMID 21075512 DOI: 10.1016/J.Canlet.2010.10.013  0.801
2010 Duensing S, Darr S, Cuevas R, Melquiot N, Brickner AG, Duensing A, Münger K. Tripeptidyl Peptidase II Is Required for c-MYC-Induced Centriole Overduplication and a Novel Therapeutic Target in c-MYC-Associated Neoplasms. Genes & Cancer. 1: 883-92. PMID 21647238 DOI: 10.1177/1947601910389605  0.311
2010 Park JW, Pitot HC, Strati K, Spardy N, Duensing S, Grompe M, Lambert PF. Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer. Cancer Research. 70: 9959-68. PMID 20935219 DOI: 10.1158/0008-5472.Can-10-1291  0.813
2010 Korzeniewski N, Cuevas R, Duensing A, Duensing S. Daughter centriole elongation is controlled by proteolysis. Molecular Biology of the Cell. 21: 3942-51. PMID 20861314 DOI: 10.1091/Mbc.E09-12-1049  0.741
2010 Duensing A, Duensing S. Centrosomes, polyploidy and cancer. Advances in Experimental Medicine and Biology. 676: 93-103. PMID 20687471 DOI: 10.1007/978-1-4419-6199-0_6  0.421
2010 Korzeniewski N, Wheeler S, Chatterjee P, Duensing A, Duensing S. A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention. Molecular Cancer. 9: 153. PMID 20565777 DOI: 10.1186/1476-4598-9-153  0.76
2010 Duensing S, Duensing A. Targeted therapies of gastrointestinal stromal tumors (GIST)--the next frontiers. Biochemical Pharmacology. 80: 575-83. PMID 20385106 DOI: 10.1016/J.Bcp.2010.04.006  0.338
2010 Bauer S, Parry JA, Mühlenberg T, Brown MF, Seneviratne D, Chatterjee P, Chin A, Rubin BP, Kuan SF, Fletcher JA, Duensing S, Duensing A. Proapoptotic activity of bortezomib in gastrointestinal stromal tumor cells. Cancer Research. 70: 150-9. PMID 20028860 DOI: 10.1158/0008-5472.Can-09-1449  0.377
2010 Ho KS, Day R, Perkins A, Xu J, Kuan S, Duensing A, Cranston RD, Duensing S. Gamma-tubulin and 53BP1 as candidate biomarkers of human papillomavirus-associated anal dysplasia. Infectious Agents and Cancer. 5: 1-2. DOI: 10.1186/1750-9378-5-S1-A29  0.381
2010 Korzeniewski N, Duensing A, Duensing S. Abstract 5354: HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of PLK4, a master regulator of centriole biogenesis Cancer Research. 70: 5354-5354. DOI: 10.1158/1538-7445.Am10-5354  0.808
2010 Cuevas RA, Duensing A, Duensing S. Abstract 2974: Cep57 is a novel regulator of centriole overduplication in tumor cells Cancer Research. 70: 2974-2974. DOI: 10.1158/1538-7445.Am10-2974  0.467
2009 Spardy N, Covella K, Cha E, Hoskins EE, Wells SI, Duensing A, Duensing S. Human papillomavirus 16 E7 oncoprotein attenuates DNA damage checkpoint control by increasing the proteolytic turnover of claspin. Cancer Research. 69: 7022-9. PMID 19706760 DOI: 10.1158/0008-5472.Can-09-0925  0.815
2009 Korzeniewski N, Zheng L, Cuevas R, Parry J, Chatterjee P, Anderton B, Duensing A, Münger K, Duensing S. Cullin 1 functions as a centrosomal suppressor of centriole multiplication by regulating polo-like kinase 4 protein levels. Cancer Research. 69: 6668-75. PMID 19679553 DOI: 10.1158/0008-5472.Can-09-1284  0.769
2009 Tsang WY, Spektor A, Vijayakumar S, Bista BR, Li J, Sanchez I, Duensing S, Dynlacht BD. Cep76, a centrosomal protein that specifically restrains centriole reduplication. Developmental Cell. 16: 649-60. PMID 19460342 DOI: 10.1016/J.Devcel.2009.03.004  0.397
2009 Duensing A, Spardy N, Chatterjee P, Zheng L, Parry J, Cuevas R, Korzeniewski N, Duensing S. Centrosome overduplication, chromosomal instability, and human papillomavirus oncoproteins. Environmental and Molecular Mutagenesis. 50: 741-7. PMID 19326465 DOI: 10.1002/Em.20478  0.794
2009 Hoskins EE, Morris TA, Higginbotham JM, Spardy N, Cha E, Kelly P, Williams DA, Wikenheiser-Brokamp KA, Duensing S, Wells SI. Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture. Oncogene. 28: 674-85. PMID 19015634 DOI: 10.1038/Onc.2008.416  0.817
2008 Spardy N, Duensing A, Hoskins EE, Wells SI, Duensing S. HPV-16 E7 reveals a link between DNA replication stress, fanconi anemia D2 protein, and alternative lengthening of telomere-associated promyelocytic leukemia bodies. Cancer Research. 68: 9954-63. PMID 19047177 DOI: 10.1158/0008-5472.Can-08-0224  0.823
2008 Cizmecioglu O, Warnke S, Arnold M, Duensing S, Hoffmann I. Plk2 regulated centriole duplication is dependent on its localization to the centrioles and a functional polo-box domain. Cell Cycle (Georgetown, Tex.). 7: 3548-55. PMID 19001868 DOI: 10.4161/Cc.7.22.7071  0.347
2008 Liu Y, Parry JA, Chin A, Duensing S, Duensing A. Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosis. Molecular Cancer. 7: 61. PMID 18616816 DOI: 10.1186/1476-4598-7-61  0.349
2008 Duensing A, Duensing S. Centrosome-mediated chromosomal instability and steroid hormones as co factors in human papillomavirus-associated cervical carcinogenesis: small viruses help to answer big questions. Advances in Experimental Medicine and Biology. 617: 109-17. PMID 18497035 DOI: 10.1007/978-0-387-69080-3_10  0.402
2008 Duensing A, Chin A, Wang L, Kuan SF, Duensing S. Analysis of centrosome overduplication in correlation to cell division errors in high-risk human papillomavirus (HPV)-associated anal neoplasms. Virology. 372: 157-64. PMID 18036631 DOI: 10.1016/J.Virol.2007.10.030  0.515
2007 Spardy N, Duensing A, Charles D, Haines N, Nakahara T, Lambert PF, Duensing S. The human papillomavirus type 16 E7 oncoprotein activates the Fanconi anemia (FA) pathway and causes accelerated chromosomal instability in FA cells. Journal of Virology. 81: 13265-70. PMID 17898070 DOI: 10.1128/Jvi.01121-07  0.815
2007 Duensing A, Liu Y, Spardy N, Bartoli K, Tseng M, Kwon J, Teng X, Duensing S. RNA polymerase II transcription is required for human papillomavirus type 16 E7- and hydroxyurea-induced centriole overduplication Oncogene. 26: 215-223. PMID 16819507 DOI: 10.1038/Sj.Onc.1209782  0.784
2006 Duensing A, Ghanem L, Steinman RA, Liu Y, Duensing S. p21(Waf1/Cip1) deficiency stimulates centriole overduplication. Cell Cycle (Georgetown, Tex.). 5: 2899-902. PMID 17172866 DOI: 10.4161/Cc.5.24.3567  0.334
2006 Duensing A, Teng X, Liu Y, Tseng M, Spardy N, Duensing S. A role of the mitotic spindle checkpoint in the cellular response to DNA replication stress. Journal of Cellular Biochemistry. 99: 759-69. PMID 16676346 DOI: 10.1002/Jcb.20962  0.779
2006 Duensing A, Liu Y, Tseng M, Malumbres M, Barbacid M, Duensing S. Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication. Oncogene. 25: 2943-9. PMID 16331279 DOI: 10.1038/Sj.Onc.1209310  0.41
2005 Duensing S. A tentative classification of centrosome abnormalities in cancer. Cell Biology International. 29: 352-9. PMID 15890539 DOI: 10.1016/J.Cellbi.2005.03.005  0.388
2005 Duensing A, Duensing S. Guilt by association? p53 and the development of aneuploidy in cancer. Biochemical and Biophysical Research Communications. 331: 694-700. PMID 15865924 DOI: 10.1016/J.Bbrc.2005.03.157  0.377
2005 Guarguaglini G, Duncan PI, Stierhof YD, Holmström T, Duensing S, Nigg EA. The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles. Molecular Biology of the Cell. 16: 1095-107. PMID 15616186 DOI: 10.1091/Mbc.E04-10-0939  0.365
2004 Duensing S, Duensing A, Lee DC, Edwards KM, Piboonniyom SO, Manuel E, Skaltsounis L, Meijer L, Münger K. Cyclin-dependent kinase inhibitor indirubin-3'-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies. Oncogene. 23: 8206-15. PMID 15378001 DOI: 10.1038/Sj.Onc.1208012  0.526
2004 Hasskarl J, Duensing S, Manuel E, Münger K. The helix-loop-helix protein ID1 localizes to centrosomes and rapidly induces abnormal centrosome numbers. Oncogene. 23: 1930-8. PMID 14755252 DOI: 10.1038/Sj.Onc.1207310  0.399
2004 Duensing S, Münger K. Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins. International Journal of Cancer. 109: 157-62. PMID 14750163 DOI: 10.1002/Ijc.11691  0.5
2003 Balsitis SJ, Sage J, Duensing S, Münger K, Jacks T, Lambert PF. Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo. Molecular and Cellular Biology. 23: 9094-103. PMID 14645521 DOI: 10.1128/Mcb.23.24.9094-9103.2003  0.434
2003 Duensing S, Münger K. Centrosome abnormalities and genomic instability induced by human papillomavirus oncoproteins. Progress in Cell Cycle Research. 5: 383-91. PMID 14593733  0.46
2003 Duensing S, Münger K. Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members. Journal of Virology. 77: 12331-5. PMID 14581569 DOI: 10.1128/Jvi.77.22.12331-12335.2003  0.5
2003 Duensing S, Lee BH, Dal Cin P, Münger K. Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma. Molecular Cancer. 2: 30. PMID 14498992 DOI: 10.1186/1476-4598-2-30  0.347
2003 Riley RR, Duensing S, Brake T, Münger K, Lambert PF, Arbeit JM. Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis. Cancer Research. 63: 4862-71. PMID 12941807  0.365
2003 Duensing S, Münger K. Centrosomes, genomic instability, and cervical carcinogenesis. Critical Reviews in Eukaryotic Gene Expression. 13: 9-23. PMID 12839094 DOI: 10.1615/Critreveukaryotgeneexpr.V13.I1.20  0.543
2003 Genther SM, Sterling S, Duensing S, Münger K, Sattler C, Lambert PF. Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle. Journal of Virology. 77: 2832-42. PMID 12584306 DOI: 10.1128/Jvi.77.5.2832-2842.2003  0.494
2003 Piboonniyom SO, Duensing S, Swilling NW, Hasskarl J, Hinds PW, Münger K. Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability. Cancer Research. 63: 476-83. PMID 12543805  0.442
2002 Duensing S, Münger K. The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Research. 62: 7075-82. PMID 12460929  0.44
2002 Duensing S, Münger K. Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability. Oncogene. 21: 6241-8. PMID 12214255 DOI: 10.1038/Sj.Onc.1205709  0.536
2001 Münger K, Basile JR, Duensing S, Eichten A, Gonzalez SL, Grace M, Zacny VL. Biological activities and molecular targets of the human papillomavirus E7 oncoprotein. Oncogene. 20: 7888-98. PMID 11753671 DOI: 10.1038/Sj.Onc.1204860  0.53
2001 Duensing S, Duensing A, Flores ER, Do A, Lambert PF, Münger K. Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes. Journal of Virology. 75: 7712-6. PMID 11462043 DOI: 10.1128/Jvi.75.16.7712-7716.2001  0.504
2001 Keating JT, Cviko A, Riethdorf S, Riethdorf L, Quade BJ, Sun D, Duensing S, Sheets EE, Munger K, Crum CP. Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia. The American Journal of Surgical Pathology. 25: 884-891. PMID 11420459 DOI: 10.1097/00000478-200107000-00006  0.404
2001 Duensing S, Münger K. Centrosome abnormalities, genomic instability and carcinogenic progression. Biochimica Et Biophysica Acta. 1471. PMID 11342187 DOI: 10.1016/S0304-419X(00)00025-1  0.426
2000 Duensing S, Lee LY, Duensing A, Basile J, Piboonniyom S, Gonzalez S, Crum CP, Munger K. The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proceedings of the National Academy of Sciences of the United States of America. 97: 10002-7. PMID 10944189 DOI: 10.1073/Pnas.170093297  0.515
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