Year |
Citation |
Score |
2021 |
Li J, Pohl L, Schüler J, Korzeniewski N, Reimold P, Kaczorowski A, Hou W, Zschäbitz S, Nientiedt C, Jäger D, Hohenfellner M, Duensing A, Duensing S. Targeting the Proteasome in Advanced Renal Cell Carcinoma: Complexity and Limitations of Patient-Individualized Preclinical Drug Discovery. Biomedicines. 9. PMID 34072926 DOI: 10.3390/biomedicines9060627 |
0.705 |
|
2019 |
Tapia-Laliena MÁ, Korzeniewski N, Peña-Llopis S, Scholl C, Fröhling S, Hohenfellner M, Duensing A, Duensing S. Cullin 5 is a novel candidate tumor suppressor in renal cell carcinoma involved in the maintenance of genome stability. Oncogenesis. 8: 4. PMID 30631037 DOI: 10.1038/s41389-018-0110-2 |
0.754 |
|
2017 |
Heller M, Prigge ES, Kaczorowski A, von Knebel Doeberitz M, Hohenfellner M, Duensing S. APOBEC3A Expression in Penile Squamous Cell Carcinoma. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. PMID 29166639 DOI: 10.1159/000479007 |
0.425 |
|
2016 |
Hoefflin R, Lahrmann B, Warsow G, Hübschmann D, Spath C, Walter B, Chen X, Hofer L, Macher-Goeppinger S, Tolstov Y, Korzeniewski N, Duensing A, Grüllich C, Jäger D, Perner S, ... ... Duensing S, et al. Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity. Nature Communications. 7: ncomms11845. PMID 27291893 DOI: 10.1038/Ncomms11845 |
0.72 |
|
2015 |
Mang J, Korzeniewski N, Dietrich D, Sailer V, Tolstov Y, Searcy S, von Hardenberg J, Perner S, Kristiansen G, Marx A, Roth W, Herpel E, Grüllich C, Popeneciu V, Pahernik S, ... ... Duensing S, et al. Prognostic Significance and Functional Role of CEP57 in Prostate Cancer. Translational Oncology. 8: 487-96. PMID 26692530 DOI: 10.1016/J.Tranon.2015.11.004 |
0.755 |
|
2015 |
Korzeniewski N, Tosev G, Pahernik S, Hadaschik B, Hohenfellner M, Duensing S. Identification of cell-free microRNAs in the urine of patients with prostate cancer. Urologic Oncology. 33: 16.e17-22. PMID 25445383 DOI: 10.1016/J.Urolonc.2014.09.015 |
0.724 |
|
2015 |
Schneider M, Korzeniewski N, Merkle K, Schüler J, Grüllich C, Hadaschik B, Hohenfellner M, Duensing S. The tyrosine kinase inhibitor nilotinib has antineoplastic activity in prostate cancer cells but up-regulates the ERK survival signal-Implications for targeted therapies. Urologic Oncology. 33: 72.e1-7. PMID 24996772 DOI: 10.1016/J.Urolonc.2014.06.001 |
0.738 |
|
2014 |
Georgi B, Korzeniewski N, Hadaschik B, Grüllich C, Roth W, Sültmann H, Pahernik S, Hohenfellner M, Duensing S. Evolving therapeutic concepts in prostate cancer based on genome-wide analyses (review). International Journal of Oncology. 45: 1337-44. PMID 25070358 DOI: 10.3892/Ijo.2014.2567 |
0.727 |
|
2014 |
Tapia-Laliena MA, Korzeniewski N, Hohenfellner M, Duensing S. High-risk prostate cancer: a disease of genomic instability. Urologic Oncology. 32: 1101-7. PMID 24931269 DOI: 10.1016/J.Urolonc.2014.02.005 |
0.732 |
|
2014 |
Schneider M, Schüler J, Höfflin R, Korzeniewski N, Grüllich C, Roth W, Teber D, Hadaschik B, Pahernik S, Hohenfellner M, Duensing S. Phenotypic drug screening and target validation for improved personalized therapy reveal the complexity of phenotype-genotype correlations in clear cell renal cell carcinoma. Urologic Oncology. 32: 877-84. PMID 24929890 DOI: 10.1016/J.Urolonc.2014.03.011 |
0.726 |
|
2014 |
Tolstov Y, Hadaschik B, Pahernik S, Hohenfellner M, Duensing S. Human papillomaviruses in urological malignancies: a critical assessment. Urologic Oncology. 32: 46.e19-27. PMID 24140249 DOI: 10.1016/j.urolonc.2013.06.012 |
0.369 |
|
2013 |
Cuevas R, Korzeniewski N, Tolstov Y, Hohenfellner M, Duensing S. FGF-2 disrupts mitotic stability in prostate cancer through the intracellular trafficking protein CEP57. Cancer Research. 73: 1400-10. PMID 23243019 DOI: 10.1158/0008-5472.Can-12-1857 |
0.751 |
|
2013 |
Korzeniewski N, Hohenfellner M, Duensing S. The centrosome as potential target for cancer therapy and prevention. Expert Opinion On Therapeutic Targets. 17: 43-52. PMID 23062185 DOI: 10.1517/14728222.2013.731396 |
0.749 |
|
2012 |
Korzeniewski N, Hohenfellner M, Duensing S. CAND1 promotes PLK4-mediated centriole overduplication and is frequently disrupted in prostate cancer. Neoplasia (New York, N.Y.). 14: 799-806. PMID 23019411 DOI: 10.1593/Neo.12580 |
0.762 |
|
2012 |
Li J, Kim S, Kobayashi T, Liang FX, Korzeniewski N, Duensing S, Dynlacht BD. Neurl4, a novel daughter centriole protein, prevents formation of ectopic microtubule organizing centres. Embo Reports. 13: 547-53. PMID 22441691 DOI: 10.1038/Embor.2012.40 |
0.707 |
|
2011 |
Korzeniewski N, Treat B, Duensing S. The HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of Polo-like kinase 4 expression. Molecular Cancer. 10: 61. PMID 21609466 DOI: 10.1186/1476-4598-10-61 |
0.794 |
|
2011 |
Korzeniewski N, Spardy N, Duensing A, Duensing S. Genomic instability and cancer: lessons learned from human papillomaviruses. Cancer Letters. 305: 113-22. PMID 21075512 DOI: 10.1016/J.Canlet.2010.10.013 |
0.801 |
|
2010 |
Duensing S, Darr S, Cuevas R, Melquiot N, Brickner AG, Duensing A, Münger K. Tripeptidyl Peptidase II Is Required for c-MYC-Induced Centriole Overduplication and a Novel Therapeutic Target in c-MYC-Associated Neoplasms. Genes & Cancer. 1: 883-92. PMID 21647238 DOI: 10.1177/1947601910389605 |
0.311 |
|
2010 |
Park JW, Pitot HC, Strati K, Spardy N, Duensing S, Grompe M, Lambert PF. Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer. Cancer Research. 70: 9959-68. PMID 20935219 DOI: 10.1158/0008-5472.Can-10-1291 |
0.813 |
|
2010 |
Korzeniewski N, Cuevas R, Duensing A, Duensing S. Daughter centriole elongation is controlled by proteolysis. Molecular Biology of the Cell. 21: 3942-51. PMID 20861314 DOI: 10.1091/Mbc.E09-12-1049 |
0.741 |
|
2010 |
Duensing A, Duensing S. Centrosomes, polyploidy and cancer. Advances in Experimental Medicine and Biology. 676: 93-103. PMID 20687471 DOI: 10.1007/978-1-4419-6199-0_6 |
0.421 |
|
2010 |
Korzeniewski N, Wheeler S, Chatterjee P, Duensing A, Duensing S. A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention. Molecular Cancer. 9: 153. PMID 20565777 DOI: 10.1186/1476-4598-9-153 |
0.76 |
|
2010 |
Duensing S, Duensing A. Targeted therapies of gastrointestinal stromal tumors (GIST)--the next frontiers. Biochemical Pharmacology. 80: 575-83. PMID 20385106 DOI: 10.1016/J.Bcp.2010.04.006 |
0.338 |
|
2010 |
Bauer S, Parry JA, Mühlenberg T, Brown MF, Seneviratne D, Chatterjee P, Chin A, Rubin BP, Kuan SF, Fletcher JA, Duensing S, Duensing A. Proapoptotic activity of bortezomib in gastrointestinal stromal tumor cells. Cancer Research. 70: 150-9. PMID 20028860 DOI: 10.1158/0008-5472.Can-09-1449 |
0.377 |
|
2010 |
Ho KS, Day R, Perkins A, Xu J, Kuan S, Duensing A, Cranston RD, Duensing S. Gamma-tubulin and 53BP1 as candidate biomarkers of human papillomavirus-associated anal dysplasia. Infectious Agents and Cancer. 5: 1-2. DOI: 10.1186/1750-9378-5-S1-A29 |
0.381 |
|
2010 |
Korzeniewski N, Duensing A, Duensing S. Abstract 5354: HPV-16 E7 oncoprotein induces centriole multiplication through deregulation of PLK4, a master regulator of centriole biogenesis Cancer Research. 70: 5354-5354. DOI: 10.1158/1538-7445.Am10-5354 |
0.808 |
|
2010 |
Cuevas RA, Duensing A, Duensing S. Abstract 2974: Cep57 is a novel regulator of centriole overduplication in tumor cells Cancer Research. 70: 2974-2974. DOI: 10.1158/1538-7445.Am10-2974 |
0.467 |
|
2009 |
Spardy N, Covella K, Cha E, Hoskins EE, Wells SI, Duensing A, Duensing S. Human papillomavirus 16 E7 oncoprotein attenuates DNA damage checkpoint control by increasing the proteolytic turnover of claspin. Cancer Research. 69: 7022-9. PMID 19706760 DOI: 10.1158/0008-5472.Can-09-0925 |
0.815 |
|
2009 |
Korzeniewski N, Zheng L, Cuevas R, Parry J, Chatterjee P, Anderton B, Duensing A, Münger K, Duensing S. Cullin 1 functions as a centrosomal suppressor of centriole multiplication by regulating polo-like kinase 4 protein levels. Cancer Research. 69: 6668-75. PMID 19679553 DOI: 10.1158/0008-5472.Can-09-1284 |
0.769 |
|
2009 |
Tsang WY, Spektor A, Vijayakumar S, Bista BR, Li J, Sanchez I, Duensing S, Dynlacht BD. Cep76, a centrosomal protein that specifically restrains centriole reduplication. Developmental Cell. 16: 649-60. PMID 19460342 DOI: 10.1016/J.Devcel.2009.03.004 |
0.397 |
|
2009 |
Duensing A, Spardy N, Chatterjee P, Zheng L, Parry J, Cuevas R, Korzeniewski N, Duensing S. Centrosome overduplication, chromosomal instability, and human papillomavirus oncoproteins. Environmental and Molecular Mutagenesis. 50: 741-7. PMID 19326465 DOI: 10.1002/Em.20478 |
0.794 |
|
2009 |
Hoskins EE, Morris TA, Higginbotham JM, Spardy N, Cha E, Kelly P, Williams DA, Wikenheiser-Brokamp KA, Duensing S, Wells SI. Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture. Oncogene. 28: 674-85. PMID 19015634 DOI: 10.1038/Onc.2008.416 |
0.817 |
|
2008 |
Spardy N, Duensing A, Hoskins EE, Wells SI, Duensing S. HPV-16 E7 reveals a link between DNA replication stress, fanconi anemia D2 protein, and alternative lengthening of telomere-associated promyelocytic leukemia bodies. Cancer Research. 68: 9954-63. PMID 19047177 DOI: 10.1158/0008-5472.Can-08-0224 |
0.823 |
|
2008 |
Cizmecioglu O, Warnke S, Arnold M, Duensing S, Hoffmann I. Plk2 regulated centriole duplication is dependent on its localization to the centrioles and a functional polo-box domain. Cell Cycle (Georgetown, Tex.). 7: 3548-55. PMID 19001868 DOI: 10.4161/Cc.7.22.7071 |
0.347 |
|
2008 |
Liu Y, Parry JA, Chin A, Duensing S, Duensing A. Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosis. Molecular Cancer. 7: 61. PMID 18616816 DOI: 10.1186/1476-4598-7-61 |
0.349 |
|
2008 |
Duensing A, Duensing S. Centrosome-mediated chromosomal instability and steroid hormones as co factors in human papillomavirus-associated cervical carcinogenesis: small viruses help to answer big questions. Advances in Experimental Medicine and Biology. 617: 109-17. PMID 18497035 DOI: 10.1007/978-0-387-69080-3_10 |
0.402 |
|
2008 |
Duensing A, Chin A, Wang L, Kuan SF, Duensing S. Analysis of centrosome overduplication in correlation to cell division errors in high-risk human papillomavirus (HPV)-associated anal neoplasms. Virology. 372: 157-64. PMID 18036631 DOI: 10.1016/J.Virol.2007.10.030 |
0.515 |
|
2007 |
Spardy N, Duensing A, Charles D, Haines N, Nakahara T, Lambert PF, Duensing S. The human papillomavirus type 16 E7 oncoprotein activates the Fanconi anemia (FA) pathway and causes accelerated chromosomal instability in FA cells. Journal of Virology. 81: 13265-70. PMID 17898070 DOI: 10.1128/Jvi.01121-07 |
0.815 |
|
2007 |
Duensing A, Liu Y, Spardy N, Bartoli K, Tseng M, Kwon J, Teng X, Duensing S. RNA polymerase II transcription is required for human papillomavirus type 16 E7- and hydroxyurea-induced centriole overduplication Oncogene. 26: 215-223. PMID 16819507 DOI: 10.1038/Sj.Onc.1209782 |
0.784 |
|
2006 |
Duensing A, Ghanem L, Steinman RA, Liu Y, Duensing S. p21(Waf1/Cip1) deficiency stimulates centriole overduplication. Cell Cycle (Georgetown, Tex.). 5: 2899-902. PMID 17172866 DOI: 10.4161/Cc.5.24.3567 |
0.334 |
|
2006 |
Duensing A, Teng X, Liu Y, Tseng M, Spardy N, Duensing S. A role of the mitotic spindle checkpoint in the cellular response to DNA replication stress. Journal of Cellular Biochemistry. 99: 759-69. PMID 16676346 DOI: 10.1002/Jcb.20962 |
0.779 |
|
2006 |
Duensing A, Liu Y, Tseng M, Malumbres M, Barbacid M, Duensing S. Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication. Oncogene. 25: 2943-9. PMID 16331279 DOI: 10.1038/Sj.Onc.1209310 |
0.41 |
|
2005 |
Duensing S. A tentative classification of centrosome abnormalities in cancer. Cell Biology International. 29: 352-9. PMID 15890539 DOI: 10.1016/J.Cellbi.2005.03.005 |
0.388 |
|
2005 |
Duensing A, Duensing S. Guilt by association? p53 and the development of aneuploidy in cancer. Biochemical and Biophysical Research Communications. 331: 694-700. PMID 15865924 DOI: 10.1016/J.Bbrc.2005.03.157 |
0.377 |
|
2005 |
Guarguaglini G, Duncan PI, Stierhof YD, Holmström T, Duensing S, Nigg EA. The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles. Molecular Biology of the Cell. 16: 1095-107. PMID 15616186 DOI: 10.1091/Mbc.E04-10-0939 |
0.365 |
|
2004 |
Duensing S, Duensing A, Lee DC, Edwards KM, Piboonniyom SO, Manuel E, Skaltsounis L, Meijer L, Münger K. Cyclin-dependent kinase inhibitor indirubin-3'-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies. Oncogene. 23: 8206-15. PMID 15378001 DOI: 10.1038/Sj.Onc.1208012 |
0.526 |
|
2004 |
Hasskarl J, Duensing S, Manuel E, Münger K. The helix-loop-helix protein ID1 localizes to centrosomes and rapidly induces abnormal centrosome numbers. Oncogene. 23: 1930-8. PMID 14755252 DOI: 10.1038/Sj.Onc.1207310 |
0.399 |
|
2004 |
Duensing S, Münger K. Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins. International Journal of Cancer. 109: 157-62. PMID 14750163 DOI: 10.1002/Ijc.11691 |
0.5 |
|
2003 |
Balsitis SJ, Sage J, Duensing S, Münger K, Jacks T, Lambert PF. Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo. Molecular and Cellular Biology. 23: 9094-103. PMID 14645521 DOI: 10.1128/Mcb.23.24.9094-9103.2003 |
0.434 |
|
2003 |
Duensing S, Münger K. Centrosome abnormalities and genomic instability induced by human papillomavirus oncoproteins. Progress in Cell Cycle Research. 5: 383-91. PMID 14593733 |
0.46 |
|
2003 |
Duensing S, Münger K. Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members. Journal of Virology. 77: 12331-5. PMID 14581569 DOI: 10.1128/Jvi.77.22.12331-12335.2003 |
0.5 |
|
2003 |
Duensing S, Lee BH, Dal Cin P, Münger K. Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma. Molecular Cancer. 2: 30. PMID 14498992 DOI: 10.1186/1476-4598-2-30 |
0.347 |
|
2003 |
Riley RR, Duensing S, Brake T, Münger K, Lambert PF, Arbeit JM. Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis. Cancer Research. 63: 4862-71. PMID 12941807 |
0.365 |
|
2003 |
Duensing S, Münger K. Centrosomes, genomic instability, and cervical carcinogenesis. Critical Reviews in Eukaryotic Gene Expression. 13: 9-23. PMID 12839094 DOI: 10.1615/Critreveukaryotgeneexpr.V13.I1.20 |
0.543 |
|
2003 |
Genther SM, Sterling S, Duensing S, Münger K, Sattler C, Lambert PF. Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle. Journal of Virology. 77: 2832-42. PMID 12584306 DOI: 10.1128/Jvi.77.5.2832-2842.2003 |
0.494 |
|
2003 |
Piboonniyom SO, Duensing S, Swilling NW, Hasskarl J, Hinds PW, Münger K. Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability. Cancer Research. 63: 476-83. PMID 12543805 |
0.442 |
|
2002 |
Duensing S, Münger K. The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Research. 62: 7075-82. PMID 12460929 |
0.44 |
|
2002 |
Duensing S, Münger K. Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability. Oncogene. 21: 6241-8. PMID 12214255 DOI: 10.1038/Sj.Onc.1205709 |
0.536 |
|
2001 |
Münger K, Basile JR, Duensing S, Eichten A, Gonzalez SL, Grace M, Zacny VL. Biological activities and molecular targets of the human papillomavirus E7 oncoprotein. Oncogene. 20: 7888-98. PMID 11753671 DOI: 10.1038/Sj.Onc.1204860 |
0.53 |
|
2001 |
Duensing S, Duensing A, Flores ER, Do A, Lambert PF, Münger K. Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes. Journal of Virology. 75: 7712-6. PMID 11462043 DOI: 10.1128/Jvi.75.16.7712-7716.2001 |
0.504 |
|
2001 |
Keating JT, Cviko A, Riethdorf S, Riethdorf L, Quade BJ, Sun D, Duensing S, Sheets EE, Munger K, Crum CP. Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia. The American Journal of Surgical Pathology. 25: 884-891. PMID 11420459 DOI: 10.1097/00000478-200107000-00006 |
0.404 |
|
2001 |
Duensing S, Münger K. Centrosome abnormalities, genomic instability and carcinogenic progression. Biochimica Et Biophysica Acta. 1471. PMID 11342187 DOI: 10.1016/S0304-419X(00)00025-1 |
0.426 |
|
2000 |
Duensing S, Lee LY, Duensing A, Basile J, Piboonniyom S, Gonzalez S, Crum CP, Munger K. The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proceedings of the National Academy of Sciences of the United States of America. 97: 10002-7. PMID 10944189 DOI: 10.1073/Pnas.170093297 |
0.515 |
|
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