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Todd C. Bradley, Ph.D. - Publications

Affiliations: 
2013 Pathology & Laboratory Medicine University of Kansas, Lawrence, KS, United States 
Area:
Molecular Biology
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Evangelous TD, Berry M, Venkatayogi S, LeMaster C, Geanes ES, De Naeyer N, DeMarco T, Shen X, Li H, Hora B, Solomonis N, Misamore J, Lewis MG, Denny TN, Montefiori D, ... ... Bradley T, et al. Host immunity associated with spontaneous suppression of viremia in therapy-naïve young rhesus macaques following neonatal SHIV infection. Journal of Virology. e0109423. PMID 37874153 DOI: 10.1128/jvi.01094-23  0.474
2023 Kulkarni S, Endsley JJ, Lai Z, Bradley T, Sharan R. Single-Cell Transcriptomics of /HIV Co-Infection. Cells. 12. PMID 37759517 DOI: 10.3390/cells12182295  0.386
2022 Pollara J, Khanal S, Edwards RW, Hora B, Ferrari G, Haynes BF, Bradley T. Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy. Bmc Immunology. 23: 48. PMID 36175869 DOI: 10.1186/s12865-022-00523-2  0.453
2022 Fraley ER, Khanal S, Pierce SH, LeMaster CA, McLennan R, Pastinen T, Bradley T. Effects of Prior Infection with SARS-CoV-2 on B Cell Receptor Repertoire Response during Vaccination. Vaccines. 10. PMID 36146555 DOI: 10.3390/vaccines10091477  0.364
2022 LeMaster C, Geanes ES, Fraley ER, Selvarangan R, Bradley T. Vaccination after SARS-CoV-2 infection increased antibody avidity against the Omicron variant compared to vaccination alone. The Journal of Infectious Diseases. PMID 35714328 DOI: 10.1093/infdis/jiac247  0.41
2022 Geanes ES, LeMaster C, Fraley ER, Khanal S, McLennan R, Grundberg E, Selvarangan R, Bradley T. Cross-reactive antibodies elicited to conserved epitopes on SARS-CoV-2 spike protein after infection and vaccination. Scientific Reports. 12: 6496. PMID 35444221 DOI: 10.1038/s41598-022-10230-y  0.426
2021 Nyanhete TE, Edwards RJ, LaBranche CC, Mansouri K, Eaton A, Dennison SM, Saunders KO, Goodman D, Janowska K, Spreng RL, Zhang L, Mudrak SV, Hope TJ, Hora B, Bradley T, et al. Polyclonal Broadly Neutralizing Antibody Activity Characterized by CD4 Binding Site and V3-Glycan Antibodies in a Subset of HIV-1 Virus Controllers. Frontiers in Immunology. 12: 670561. PMID 35003053 DOI: 10.3389/fimmu.2021.670561  0.539
2021 Fraley E, LeMaster C, Khanal S, Banerjee D, Pastinen T, Grundberg E, Selvarangan R, Bradley T. Prior infection and age impacts antibody persistence after SARS-CoV-2 mRNA vaccine. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 34551091 DOI: 10.1093/cid/ciab850  0.411
2021 Fraley E, LeMaster C, Geanes E, Banerjee D, Khanal S, Grundberg E, Selvarangan R, Bradley T. Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals. Bmc Medicine. 19: 169. PMID 34304742 DOI: 10.1186/s12916-021-02055-9  0.376
2021 Williams WB, Meyerhoff RR, Edwards RJ, Li H, Manne K, Nicely NI, Henderson R, Zhou Y, Janowska K, Mansouri K, Gobeil S, Evangelous T, Hora B, Berry M, Abuahmad AY, ... ... Bradley T, et al. Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell. PMID 34019795 DOI: 10.1016/j.cell.2021.04.042  0.497
2021 Nielsen CM, Ogbe A, Pedroza-Pacheco I, Doeleman SE, Chen Y, Silk SE, Barrett JR, Elias SC, Miura K, Diouf A, Bardelli M, Dabbs RA, Barfod L, Long CA, Haynes BF, ... ... Bradley T, et al. Protein/AS01 vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors. Cell Reports. Medicine. 2: 100207. PMID 33763653 DOI: 10.1016/j.xcrm.2021.100207  0.413
2021 Bradley T, Grundberg E, Selvarangan R, LeMaster C, Fraley E, Banerjee D, Belden B, Louiselle D, Nolte N, Biswell R, Pastinen T, Myers A, Schuster J. Antibody Responses after a Single Dose of SARS-CoV-2 mRNA Vaccine. The New England Journal of Medicine. PMID 33755375 DOI: 10.1056/NEJMc2102051  0.337
2021 Bradley T, Grundberg E, Selvarangan R. Antibody responses boosted in seropositive healthcare workers after single dose of SARS-CoV-2 mRNA vaccine. Medrxiv : the Preprint Server For Health Sciences. PMID 33564797 DOI: 10.1101/2021.02.03.21251078  0.374
2020 Li D, Bradley T, Cain DW, Pedroza-Pacheco I, Aggelakopoulou M, Parks R, Barr M, Xia SM, Scearce R, Bowman C, Stevens G, Newman A, Hora B, Chen Y, Riebe K, et al. -Deficient Mice Exhibit Cytokine-Related Transcriptomic Signatures. Immunohorizons. 4: 713-728. PMID 33172842 DOI: 10.4049/immunohorizons.2000088  0.424
2020 Pierce S, Geanes ES, Bradley T. Targeting Natural Killer Cells for Improved Immunity and Control of the Adaptive Immune Response. Frontiers in Cellular and Infection Microbiology. 10: 231. PMID 32509600 DOI: 10.3389/Fcimb.2020.00231  0.385
2020 Bradley T, Kuraoka M, Yeh CH, Tian M, Chen H, Cain DW, Chen X, Cheng C, Ellebedy AH, Parks R, Barr M, Sutherland LL, Scearce RM, Bowman CM, Bouton-Verville H, et al. Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948. PMID 32075963 DOI: 10.1038/S41467-020-14670-W  0.659
2020 Han Q, Bradley T, Williams WB, Cain DW, Montefiori DC, Saunders KO, Parks RJ, Edwards RW, Ferrari G, Mueller O, Shen X, Wiehe KJ, Reed S, Fox CB, Rountree W, et al. Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization. Cell Reports. 30: 1553-1569.e6. PMID 32023469 DOI: 10.1016/J.Celrep.2019.12.091  0.523
2019 Saunders KO, Wiehe K, Tian M, Acharya P, Bradley T, Alam SM, Go EP, Scearce R, Sutherland L, Henderson R, Hsu AL, Borgnia MJ, Chen H, Lu X, Wu NR, et al. Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science (New York, N.Y.). 366. PMID 31806786 DOI: 10.1126/Science.Aay7199  0.591
2019 Nyanhete TE, Frisbee AL, Bradley T, Faison WJ, Robins E, Payne T, Freel SA, Sawant S, Weinhold KJ, Wiehe K, Haynes BF, Ferrari G, Li QJ, Moody MA, Tomaras GD. HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers. Scientific Reports. 9: 10165. PMID 31308388 DOI: 10.1038/S41598-019-46462-8  0.367
2018 Bradley T, Ferrari G, Haynes BF, Margolis DM, Browne EP. Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency. Cell Reports. 25: 107-117.e3. PMID 30282021 DOI: 10.1016/J.Celrep.2018.09.020  0.475
2018 Bradley T, Peppa D, Pedroza-Pacheco I, Li D, Cain DW, Henao R, Venkat V, Hora B, Chen Y, Vandergrift NA, Overman RG, Edwards RW, Woods CW, Tomaras GD, Ferrari G, et al. RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses. Cell. PMID 30270043 DOI: 10.1016/J.Cell.2018.08.064  0.573
2018 Ackerman ME, Das J, Pittala S, Broge T, Linde C, Suscovich TJ, Brown EP, Bradley T, Natarajan H, Lin S, Sassic JK, O'Keefe S, Mehta N, Goodman D, Sips M, et al. Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV. Nature Medicine. PMID 30177821 DOI: 10.1038/S41591-018-0161-0  0.538
2018 Madani N, Princiotto AM, Mach L, Ding S, Prevost J, Richard J, Hora B, Sutherland L, Zhao CA, Conn BP, Bradley T, Moody MA, Melillo B, Finzi A, Haynes BF, et al. A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge. Nature Communications. 9: 2363. PMID 29915222 DOI: 10.1038/S41467-018-04758-9  0.599
2018 Wiehe K, Bradley T, Meyerhoff RR, Hart C, Williams WB, Easterhoff D, Faison WJ, Kepler TB, Saunders KO, Alam SM, Bonsignori M, Haynes BF. Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development. Cell Host & Microbe. PMID 29861171 DOI: 10.1016/J.Chom.2018.04.018  0.441
2018 Saunders KO, Santra S, Parks R, Yates NL, Sutherland LL, Scearce RM, Balachandran H, Bradley T, Goodman D, Eaton A, Stanfield-Oakley SA, Tartaglia J, Phogat S, Pantaleo G, Esteban M, et al. Immunogenicity of NYVAC prime-protein boost HIV-1 envelope vaccination and SHIV challenge of nonhuman primates. Journal of Virology. PMID 29437967 DOI: 10.1128/Jvi.02035-17  0.624
2017 Williams WB, Zhang J, Jiang C, Nicely NI, Fera D, Luo K, Moody MA, Liao HX, Alam SM, Kepler TB, Ramesh A, Wiehe K, Holland JA, Bradley T, Vandergrift N, et al. Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nature Communications. 8: 1732. PMID 29170366 DOI: 10.1038/S41467-017-01336-3  0.629
2017 Williams LD, Ofek G, Schätzle S, McDaniel JR, Lu X, Nicely NI, Wu L, Lougheed CS, Bradley T, Louder MK, McKee K, Bailer RT, O'Dell S, Georgiev IS, Seaman MS, et al. Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Science Immunology. 2. PMID 28783671 DOI: 10.1126/Sciimmunol.Aal2200  0.55
2017 Bradley T, Pollara J, Santra S, Vandergrift N, Pittala S, Bailey-Kellogg C, Shen X, Parks R, Goodman D, Eaton A, Balachandran H, Mach LV, Saunders KO, Weiner JA, Scearce R, et al. Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge. Nature Communications. 8: 15711. PMID 28593989 DOI: 10.1038/Ncomms15711  0.611
2017 Bonsignori M, Kreider EF, Fera D, Meyerhoff RR, Bradley T, Wiehe K, Alam SM, Aussedat B, Walkowicz WE, Hwang KK, Saunders KO, Zhang R, Gladden MA, Monroe A, Kumar A, et al. Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Science Translational Medicine. 9. PMID 28298420 DOI: 10.1126/Scitranslmed.Aai7514  0.595
2017 Bradley T, Hart C, Hora B, Pollara J, Browne EP, Moody MA, Ferrari G, Margolis D, Haynes BF. High-throughput single-cell transcriptome analysis of immune cells from HIV-1 infected individuals before and after therapy Journal of Virus Eradication. 3: 31. DOI: 10.1016/S2055-6640(20)30548-3  0.479
2016 Bradley T, Yang G, Ilkayeva O, Holl TM, Zhang R, Zhang J, Santra S, Fox CB, Reed SG, Parks R, Bowman CM, Bouton-Verville H, Sutherland LL, Scearce RM, Vandergrift N, et al. HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism. Journal of Immunology (Baltimore, Md. : 1950). PMID 27849170 DOI: 10.4049/Jimmunol.1601484  0.529
2016 Ding S, Verly MM, Princiotto A, Melillo B, Moody T, Bradley T, Easterhoff D, Roger M, Hahn BH, Madani N, Smith Iii AB, Haynes BF, Sodroski JG, Finzi A. Small Molecule CD4-Mimetics Sensitize HIV-1-infected Cells to ADCC by Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Non-Human Primates. Aids Research and Human Retroviruses. PMID 27846736 DOI: 10.1089/Aid.2016.0246  0.63
2016 Bradley T, Trama A, Tumba N, Gray E, Lu X, Madani N, Jahanbakhsh F, Eaton A, Xia SM, Parks R, Lloyd KE, Sutherland LL, Scearce RM, Bowman CM, Barnett S, et al. Amino Acid Changes in the HIV-1 gp41 Membrane Proximal Region Control Virus Neutralization Sensitivity. Ebiomedicine. PMID 27612593 DOI: 10.1016/J.Ebiom.2016.08.045  0.586
2016 Zhang R, Verkoczy L, Wiehe K, Munir Alam S, Nicely NI, Santra S, Bradley T, Pemble CW, Zhang J, Gao F, Montefiori DC, Bouton-Verville H, Kelsoe G, Larimore K, Greenberg PD, et al. Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Science Translational Medicine. 8: 336ra62. PMID 27122615 DOI: 10.1126/Scitranslmed.Aaf0618  0.585
2016 Madani N, Princiotto AM, Easterhoff D, Bradley T, Luo K, Williams WB, Liao HX, Moody MA, Phad GE, Bernat NV, Melillo B, Santra S, Smith AB, Karlsson Hedestam GB, Haynes B, et al. Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds. Journal of Virology. PMID 26962221 DOI: 10.1128/Jvi.03211-15  0.581
2016 Bonsignori M, Zhou T, Sheng Z, Chen L, Gao F, Joyce MG, Ozorowski G, Chuang GY, Schramm CA, Wiehe K, Alam SM, Bradley T, Gladden MA, Hwang KK, Iyengar S, et al. Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody. Cell. PMID 26949186 DOI: 10.1016/J.Cell.2016.02.022  0.498
2015 Bradley T, Fera D, Bhiman J, Eslamizar L, Lu X, Anasti K, Zhang R, Sutherland LL, Scearce RM, Bowman CM, Stolarchuk C, Lloyd KE, Parks R, Eaton A, Foulger A, et al. Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Reports. PMID 26725118 DOI: 10.1016/J.Celrep.2015.12.017  0.629
2015 Haynes BF, Bradley T. Broadly Neutralizing Antibodies and the Development of Vaccines. Jama. 313: 2419-20. PMID 26103022 DOI: 10.1001/Jama.2015.2427  0.471
2014 Wiehe K, Easterhoff D, Luo K, Nicely NI, Bradley T, Jaeger FH, Dennison SM, Zhang R, Lloyd KE, Stolarchuk C, Parks R, Sutherland LL, Scearce RM, Morris L, Kaewkungwal J, et al. Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved. Immunity. 41: 909-18. PMID 25526306 DOI: 10.1016/J.Immuni.2014.11.014  0.547
2007 Sciascia SA, Robson K, Zhu L, Garland M, Grabosch S, Kelamis J, Messamore W, Bradley T, Sourk A, Westberg L, Goodnight W, Tongson K, Holloway N, Wardak Z, Sudyka M, et al. Immunization of nonautoimmune mice with DNA binding domains of the largest subunit of RNA polymerase I results in production of anti-dsDNA and anti-Sm/RNP antibodies. Autoimmunity. 40: 38-47. PMID 17364496 DOI: 10.1080/08916930601185550  0.354
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