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Barry M. Goldstein - Publications

Affiliations: 
Biochemistry & Biophysics University of Rochester, Rochester, NY 
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2004 Ceccarelli C, Liang ZX, Strickler M, Prehna G, Goldstein BM, Klinman JP, Bahnson BJ. Crystal Structure and Amide H/D Exchange of Binary Complexes of Alcohol Dehydrogenase from Bacillus stearothermophilus: Insight into Thermostability and Cofactor Binding Biochemistry. 43: 5266-5277. PMID 15122892 DOI: 10.1021/Bi049736P  0.73
2004 Pankiewicz KW, Patterson SE, Black PL, Jayaram HN, Risal D, Goldstein BM, Stuyver LJ, Schinazi RF. Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target. Current Medicinal Chemistry. 11: 887-900. PMID 15083807 DOI: 10.2174/0929867043455648  0.697
2003 Strickler M, Goldstein BM, Maxfield K, Shireman L, Kim G, Matteson DS, Jones JP. Crystallographic studies on the complex behavior of nicotine binding to P450cam (CYP101). Biochemistry. 42: 11943-50. PMID 14556625 DOI: 10.1021/Bi034833O  0.731
2003 Pankiewicz KW, Goldstein BM. NAD Analogues 18 — The Chemistry of Nucleoside and Dinucleotide Inhibitors of Inosine Monophosphate Dehydrogenase (IMPDH) Cheminform. 34. DOI: 10.1002/CHIN.200338231  0.314
2002 Pankiewicz KW, Watanabe KA, Lesiak-Watanabe K, Goldstein BM, Jayaram HN. The chemistry of nicotinamide adenine dinucleotide (NAD) analogues containing C-nucleosides related to nicotinamide riboside. Current Medicinal Chemistry. 9: 733-41. PMID 11966436 DOI: 10.2174/0929867024606920  0.377
2002 French KJ, Rock DA, Rock DA, Manchester JI, Goldstein BM, Jones JP. Active site mutations of cytochrome p450cam alter the binding, coupling, and oxidation of the foreign substrates (R)- and (s)-2-ethylhexanol. Archives of Biochemistry and Biophysics. 398: 188-97. PMID 11831849 DOI: 10.1006/Abbi.2001.2732  0.733
2002 Pankiewicz KW, Lesiak-Watanabe KB, Watanabe KA, Patterson SE, Jayaram HN, Yalowitz JA, Miller MD, Seidman M, Majumdar A, Prehna G, Goldstein BM. Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia. Journal of Medicinal Chemistry. 45: 703-12. PMID 11806722 DOI: 10.1021/Jm0104116  0.349
2002 Clark JL, Patterson SE, Mason JC, Otto MJ, Schinazi RF, Watanabe KA, Risal D, Goldstein BM, Pankiewicz KW. Novel inhibitors of inosine monophosphate dehydrogenase (IMPDH) Collection of Czechoslovak Chemical Communications. 5: 256-260. DOI: 10.1135/Css200205256  0.693
2001 French KJ, Strickler MD, Rock DA, Rock DA, Bennett GA, Wahlstrom JL, Goldstein BM, Jones JP. Benign synthesis of 2-ethylhexanoic acid by cytochrome P450cam: enzymatic, crystallographic, and theoretical studies. Biochemistry. 40: 9532-8. PMID 11583152 DOI: 10.1021/Bi010063+  0.706
2000 Goldstein BM, Colby TD. Conformational constraints in NAD analogs: implications for dehydrogenase binding and specificity. Advances in Enzyme Regulation. 40: 405-426. PMID 10828360 DOI: 10.1016/S0065-2571(99)00056-4  0.333
2000 Franchetti P, Marchetti S, Cappellacci L, Jayaram HN, Yalowitz JA, Goldstein BM, Barascut JL, Dukhan D, Imbach JL, Grifantini M. Synthesis, conformational analysis, and biological activity of C-thioribonucleosides related to tiazofurin. Journal of Medicinal Chemistry. 43: 1264-70. PMID 10753464 DOI: 10.1021/Jm990257B  0.301
1999 Colby TD, Vanderveen K, Strickler MD, Markham GD, Goldstein BM. Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design. Proceedings of the National Academy of Sciences of the United States of America. 96: 3531-3536. PMID 10097070 DOI: 10.1073/Pnas.96.7.3531  0.737
1998 Colby TD, Bahnson BJ, Chin JK, Klinman JP, Goldstein BM. Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes. Biochemistry. 37: 9295-304. PMID 9649310 DOI: 10.1021/Bi973184B  0.365
1998 Lesiak K, Watanabe KA, Majumdar A, Powell J, Seidman M, Vanderveen K, Goldstein BM, Pankiewicz KW. Synthesis of a Methylenebis(phosphonate) Analogue of Mycophenolic Adenine Dinucleotide: A Glucuronidation-Resistant MAD Analogue of NAD Journal of Medicinal Chemistry. 41: 618-622. PMID 9484510 DOI: 10.1021/Jm970705K  0.334
1997 Bahnson BJ, Colby TD, Chin JK, Goldstein BM, Klinman JP. A link between protein structure and enzyme catalyzed hydrogen tunneling. Proceedings of the National Academy of Sciences of the United States of America. 94: 12797-802. PMID 9371755 DOI: 10.1073/Pnas.94.24.12797  0.352
1997 Lesiak K, Watanabe KA, Majumdar A, Seidman M, Vanderveen K, Goldstein BM, Pankiewicz KW. Synthesis of nonhydrolyzable analogues of thiazole-4-carboxamide and benzamide adenine dinucleotide containing fluorine atom at the C2' of adenine nucleoside: induction of K562 differentiation and inosine monophosphate dehydrogenase inhibitory activity. Journal of Medicinal Chemistry. 40: 2533-2538. PMID 9258359 DOI: 10.1021/Jm970247F  0.345
1997 Franchetti P, Cappellacci L, Sheikha GA, Jayaram HN, Gurudutt VV, Sint T, Schneider BP, Jones WD, Goldstein BM, Perra G, De Montis A, Loi AG, La Colla P, Grifantini M. Synthesis, structure, and antiproliferative activity of selenophenfurin, an inosine 5'-monophosphate dehydrogenase inhibitor analogue of selenazofurin. Journal of Medicinal Chemistry. 40: 1731-7. PMID 9171883 DOI: 10.1021/Jm960864O  0.318
1997 Cappellacci L, Franchetti P, Sheikha GA, Jayaram HN, Gurudutt VV, Sint T, Schneider BP, Goldstein BM, Perra G, Poma S, La Colla P, Grifantini M. Synthesis and Cytotoxic Activity of Selenophenfurin, a New Inhibitor of IMP Dehydrogenase Nucleosides and Nucleotides. 16: 1045-1048. DOI: 10.1080/07328319708006129  0.37
1995 Zatorski A, Goldstein BM, Colby TD, Jones JP, Pankiewicz KW. Potent inhibitors of human inosine monophosphate dehydrogenase type II. Fluorine-substituted analogues of thiazole-4-carboxamide adenine dinucleotide. Journal of Medicinal Chemistry. 38: 1098-105. PMID 7707313 DOI: 10.1021/Jm00007A007  0.37
1994 Goldstein BM, Li H, Jones JP, Bell JE, Zeidler J, Pankiewicz KW, Watanabe KA. CNAD: a potent and specific inhibitor of alcohol dehydrogenase. Journal of Medicinal Chemistry. 37: 392-9. PMID 8308865 DOI: 10.1021/Jm00029A011  0.438
1994 Li H, Hallows WH, Punzi JS, Marquez VE, Carrell HL, Pankiewicz KW, Watanabe KA, Goldstein BM. Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin. Biochemistry. 33: 23-32. PMID 8286346 DOI: 10.1021/Bi00167A004  0.345
1994 Goldstein BM, Li H, Hallows WH, Langs DA, Franchetti P, Cappellacci L, Grifantini M. C-glycosyl bond conformation in oxazofurin: crystallographic and computational studies of the oxazole analogue of tiazofurin. Journal of Medicinal Chemistry. 37: 1684-8. PMID 8201602 DOI: 10.1021/Jm00037A019  0.311
1993 Li H, Kennedy SD, Goldstein BM. Solid-state and solution conformations of isotiazofurin: crystallographic, computational and 1H NMR studies. Acta Crystallographica. Section B, Structural Science. 49: 729-38. PMID 8397981 DOI: 10.1107/S0108768193001053  0.31
1993 Pankiewicz KW, Zeidler J, Ciszewski LA, Bell JE, Goldstein BM, Jayaram HN, Watanabe KA. Synthesis of isosteric analogues of nicotinamide adenine dinucleotide containing C-nucleotide of nicotinamide or picolinamide. Journal of Medicinal Chemistry. 36: 1855-9. PMID 8099976 DOI: 10.1021/Jm00065A008  0.339
1992 Li H, Goldstein BM. Carboxamide group conformation in the nicotinamide and thiazole-4-carboxamide rings: implications for enzyme binding. Journal of Medicinal Chemistry. 35: 3560-7. PMID 1357174 DOI: 10.1021/Jm00097A013  0.337
1991 Goldstein BM, Leary JF, Farley BA, Marquez VE, Levy PC, Rowley PT. Induction of HL60 cell differentiation by tiazofurin and its analogues: characterization and efficacy. Blood. 78: 593-8. PMID 1650262 DOI: 10.1182/Blood.V78.3.593.593  0.324
1990 Goldstein BM, Bell JE, Marquez VE. Dehydrogenase binding by tiazofurin anabolites. Journal of Medicinal Chemistry. 33: 1123-7. PMID 1969483 DOI: 10.1021/JM00166A007  0.325
1989 Tseng CK, Marquez VE, Fuller RW, Goldstein BM, Haines DR, McPherson H, Parsons JL, Shannon WM, Arnett G, Hollingshead M. Synthesis of 3-deazaneplanocin A, a powerful inhibitor of S-adenosylhomocysteine hydrolase with potent and selective in vitro and in vivo antiviral activities. Journal of Medicinal Chemistry. 32: 1442-6. PMID 2544721 DOI: 10.1021/Jm00127A007  0.357
1988 Goldstein BM, Bell JE, Marquez VE. Dehydrogenase binding by cofactor analogues Biochemical Society Transactions. 16: 862-863. DOI: 10.1042/Bst0160862  0.339
1987 Banerjee A, Levy HR, Levy GC, LiMuti C, Goldstein BM, Bell JE. A transfer nuclear Overhauser effect study of coenzyme binding to distinct sites in binary and ternary complexes in glutamate dehydrogenase. Biochemistry. 26: 8443-50. PMID 3442667 DOI: 10.1021/Bi00399A062  0.32
1986 Goldstein BM, Barton JK, Berman HM. Crystal and molecular structure of a chiral-specific DNA-binding agent: tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) Inorganic Chemistry. 25: 842-847. DOI: 10.1002/Chin.198628304  0.317
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