Year |
Citation |
Score |
2024 |
Ren H, Huang C, Pan Y, Dommaraju SR, Cui H, Li M, Gadgil MG, Mitchell DA, Zhao H. Non-modular fatty acid synthases yield distinct N-terminal acylation in ribosomal peptides. Nature Chemistry. PMID 38528101 DOI: 10.1038/s41557-024-01491-3 |
0.342 |
|
2024 |
Lee AR, Carter RS, Imani AS, Dommaraju SR, Hudson GA, Mitchell DA, Freeman MF. Computationally guided exploration of borosin biosynthetic strategies. Biorxiv : the Preprint Server For Biology. PMID 38260703 DOI: 10.1101/2024.01.09.574750 |
0.805 |
|
2024 |
Fernandez HN, Kretsch AM, Kunakom S, Kadjo AE, Mitchell DA, Eustáquio AS. High-Yield Lasso Peptide Production in a Bacterial Host by Plasmid Copy Number Engineering. Acs Synthetic Biology. PMID 38194362 DOI: 10.1021/acssynbio.3c00597 |
0.43 |
|
2023 |
Woodard AM, Peccati F, Navo CD, Jiménez-Osés G, Mitchell DA. Benzylic Radical Stabilization Permits Ether Formation During Darobactin Biosynthesis. Biorxiv : the Preprint Server For Biology. PMID 38076856 DOI: 10.1101/2023.11.29.569256 |
0.314 |
|
2023 |
Saad H, Majer T, Bhattarai K, Lampe S, Nguyen DT, Kramer M, Straetener J, Brötz-Oesterhelt H, Mitchell DA, Gross H. Bioinformatics-guided discovery of biaryl-linked lasso peptides. Chemical Science. 14: 13176-13183. PMID 38023510 DOI: 10.1039/d3sc02380j |
0.482 |
|
2023 |
Nguyen DT, Zhu L, Mitchell DA, van der Donk WA. Discovery of biaryl macrocyclic peptides with C-terminal β-amino-α-keto acid groups. Biorxiv : the Preprint Server For Biology. PMID 37965205 DOI: 10.1101/2023.10.30.564719 |
0.442 |
|
2023 |
Ren H, Huang C, Pan Y, Cui H, Dommaraju SR, Mitchell DA, Zhao H. Non-modular Fatty Acid Synthases Yield Unique Acylation in Ribosomal Peptides. Biorxiv : the Preprint Server For Biology. PMID 37961664 DOI: 10.1101/2023.10.25.564083 |
0.332 |
|
2023 |
Precord TW, Ramesh S, Dommaraju SR, Harris LA, Kille BL, Mitchell DA. Catalytic Site Proximity Profiling for Functional Unification of Sequence-Diverse Radical -Adenosylmethionine Enzymes. Acs Bio & Med Chem Au. 3: 240-251. PMID 37363077 DOI: 10.1021/acsbiomedchemau.2c00085 |
0.821 |
|
2023 |
Chadwick GL, Joiner AMN, Ramesh S, Mitchell DA, Nayak DD. McrD binds asymmetrically to methyl-coenzyme M reductase improving active-site accessibility during assembly. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302815120. PMID 37307484 DOI: 10.1073/pnas.2302815120 |
0.787 |
|
2023 |
Ren H, Dommaraju SR, Huang C, Cui H, Pan Y, Nesic M, Zhu L, Sarlah D, Mitchell DA, Zhao H. Genome mining unveils a class of ribosomal peptides with two amino termini. Nature Communications. 14: 1624. PMID 36959188 DOI: 10.1038/s41467-023-37287-1 |
0.42 |
|
2023 |
Saad H, Majer T, Bhattarai K, Lampe S, Nguyen DT, Kramer M, Straetener J, Br Tz-Oesterhelt H, Mitchell DA, Gross H. Bioinformatics-Guided Discovery of Biaryl-Tailored Lasso Peptides. Biorxiv : the Preprint Server For Biology. PMID 36945544 DOI: 10.1101/2023.03.06.531328 |
0.477 |
|
2023 |
Ren H, Dommaraju SR, Huang C, Cui H, Pan Y, Nesic M, Zhu L, Sarlah D, Mitchell DA, Zhao H. Genome mining unveils a class of ribosomal peptides with two amino termini. Biorxiv : the Preprint Server For Biology. PMID 36945508 DOI: 10.1101/2023.03.08.531785 |
0.425 |
|
2023 |
Kretsch AM, Gadgil MG, DiCaprio AJ, Barrett SE, Kille BL, Si Y, Zhu L, Mitchell DA. Peptidase Activation by a Leader Peptide-Bound RiPP Recognition Element. Biochemistry. PMID 36734655 DOI: 10.1021/acs.biochem.2c00700 |
0.837 |
|
2022 |
Shelton KE, Mitchell DA. Bioinformatic prediction and experimental validation of RiPP recognition elements. Methods in Enzymology. 679: 191-233. PMID 36682862 DOI: 10.1016/bs.mie.2022.08.050 |
0.405 |
|
2022 |
Rice AJ, Pelton JM, Kramer NJ, Catlin DS, Nair SK, Pogorelov TV, Mitchell DA, Bowers AA. Enzymatic Pyridine Aromatization during Thiopeptide Biosynthesis. Journal of the American Chemical Society. PMID 36351243 DOI: 10.1021/jacs.2c07377 |
0.478 |
|
2022 |
Ayikpoe RS, Shi C, Battiste AJ, Eslami SM, Ramesh S, Simon MA, Bothwell IR, Lee H, Rice AJ, Ren H, Tian Q, Harris LA, Sarksian R, Zhu L, Frerk AM, ... ... Mitchell DA, et al. A scalable platform to discover antimicrobials of ribosomal origin. Nature Communications. 13: 6135. PMID 36253467 DOI: 10.1038/s41467-022-33890-w |
0.827 |
|
2022 |
Ongpipattanakul C, Desormeaux EK, DiCaprio A, van der Donk WA, Mitchell DA, Nair SK. Mechanism of Action of Ribosomally Synthesized and Post-Translationally Modified Peptides. Chemical Reviews. PMID 36049139 DOI: 10.1021/acs.chemrev.2c00210 |
0.831 |
|
2022 |
Nguyen DT, Le TT, Rice AJ, Hudson GA, van der Donk WA, Mitchell DA. Accessing Diverse Pyridine-Based Macrocyclic Peptides by a Two-Site Recognition Pathway. Journal of the American Chemical Society. PMID 35713415 DOI: 10.1021/jacs.2c02824 |
0.818 |
|
2022 |
Mitchell D, Precord T, Hudson G, Mahanta N, Burkhart B, Gerlt J. Radical SAM Enzymes and the Unexplored Chemistry of RiPP Biosynthesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35556269 DOI: 10.1096/fasebj.2022.36.S1.0I185 |
0.315 |
|
2021 |
Ramesh S, Guo X, DiCaprio AJ, De Lio AM, Harris LA, Kille BL, Pogorelov TV, Mitchell DA. Bioinformatics-Guided Expansion and Discovery of Graspetides. Acs Chemical Biology. 16: 2787-2797. PMID 34766760 DOI: 10.1021/acschembio.1c00672 |
0.805 |
|
2021 |
Precord TW, Mahanta N, Mitchell DA. Correction to "Reconstitution and Substrate Specificity of the Thioether-Forming Radical -Adenosylmethionine Enzyme in Freyrasin Biosynthesis". Acs Chemical Biology. PMID 34428027 DOI: 10.1021/acschembio.1c00536 |
0.707 |
|
2021 |
Liu A, Krushnamurthy PH, Subramanya KS, Mitchell DA, Mahanta N. Enzymatic thioamidation of peptide backbones. Methods in Enzymology. 656: 459-494. PMID 34325795 DOI: 10.1016/bs.mie.2021.04.010 |
0.827 |
|
2021 |
Hudson GA, Burkhart BJ, DiCaprio AJ, Schwalen CJ, Kille B, Pogorelov TV, Mitchell DA. Correction to "Bioinformatic Mapping of Radical -Adenosylmethionine-Dependent Ribosomally Synthesized and Post-Translationally Modified Peptides Identifies New Cα, Cβ, and Cγ-Linked Thioether-Containing Peptides". Journal of the American Chemical Society. PMID 34197098 DOI: 10.1021/jacs.1c06285 |
0.815 |
|
2021 |
Si Y, Kretsch AM, Daigh LM, Burk MJ, Mitchell DA. Cell-Free Biosynthesis to Evaluate Lasso Peptide Formation and Enzyme-Substrate Tolerance. Journal of the American Chemical Society. PMID 33823110 DOI: 10.1021/jacs.1c01452 |
0.477 |
|
2021 |
Liu A, Si Y, Dong SH, Mahanta N, Penkala HN, Nair SK, Mitchell DA. Functional elucidation of TfuA in peptide backbone thioamidation. Nature Chemical Biology. PMID 33707784 DOI: 10.1038/s41589-021-00771-0 |
0.86 |
|
2020 |
Harris LA, Saint-Vincent PMB, Guo X, Hudson GA, DiCaprio AJ, Zhu L, Mitchell DA. Reactivity-Based Screening for Citrulline-Containing Natural Products Reveals a Family of Bacterial Peptidyl Arginine Deiminases. Acs Chemical Biology. PMID 33249828 DOI: 10.1021/acschembio.0c00685 |
0.859 |
|
2020 |
Georgiou MA, Dommaraju SR, Guo X, Mast DH, Mitchell DA. Bioinformatic and Reactivity-Based Discovery of Linaridins. Acs Chemical Biology. PMID 33170617 DOI: 10.1021/acschembio.0c00620 |
0.814 |
|
2020 |
Montalbán-López M, Scott TA, Ramesh S, Rahman IR, van Heel AJ, Viel JH, Bandarian V, Dittmann E, Genilloud O, Goto Y, Grande Burgos MJ, Hill C, Kim S, Koehnke J, Latham JA, ... ... Mitchell DA, et al. New developments in RiPP discovery, enzymology and engineering. Natural Product Reports. PMID 32935693 DOI: 10.1039/D0Np00027B |
0.822 |
|
2020 |
Kloosterman AM, Shelton KE, van Wezel GP, Medema MH, Mitchell DA. RRE-Finder: a Genome-Mining Tool for Class-Independent RiPP Discovery. Msystems. 5. PMID 32873609 DOI: 10.1128/mSystems.00267-20 |
0.331 |
|
2020 |
Hudson GA, Hooper AR, DiCaprio AJ, Sarlah D, Mitchell DA. Structure Prediction and Synthesis of Pyridine-Based Macrocyclic Peptide Natural Products. Organic Letters. PMID 32845158 DOI: 10.1021/Acs.Orglett.0C02699 |
0.85 |
|
2020 |
Walker MC, Eslami SM, Hetrick KJ, Ackenhusen SE, Mitchell DA, van der Donk WA. Precursor peptide-targeted mining of more than one hundred thousand genomes expands the lanthipeptide natural product family. Bmc Genomics. 21: 387. PMID 32493223 DOI: 10.1186/S12864-020-06785-7 |
0.587 |
|
2020 |
Nayak DD, Liu A, Agrawal N, Rodriguez-Carerro R, Dong SH, Mitchell DA, Nair SK, Metcalf WW. Functional interactions between posttranslationally modified amino acids of methyl-coenzyme M reductase in Methanosarcina acetivorans. Plos Biology. 18: e3000507. PMID 32092071 DOI: 10.1371/Journal.Pbio.3000507 |
0.758 |
|
2020 |
Sieber S, Grendelmeier SM, Harris LA, Mitchell DA, Gademann K. Microviridin 1777: A Toxic Chymotrypsin Inhibitor Discovered by a Metabologenomic Approach. Journal of Natural Products. PMID 31989826 DOI: 10.1021/Acs.Jnatprod.9B00986 |
0.501 |
|
2019 |
Melby JO, Li X, Mitchell DA. Correction to "Orchestration of Enzymatic Processing by Thiazole/Oxazole-Modified Microcin Dehydrogenases". Biochemistry. PMID 31855405 DOI: 10.1021/Acs.Biochem.9B01042 |
0.767 |
|
2019 |
Precord TW, Mahanta N, Mitchell DA. Reconstitution and substrate specificity of the thioether-forming radical S-adenosylmethionine enzyme in freyrasin biosynthesis. Acs Chemical Biology. PMID 31449382 DOI: 10.1021/Acschembio.9B00457 |
0.811 |
|
2019 |
Hudson GA, Mitchell DA. Corrigendum to "RiPP antibiotics: biosynthesis and engineering potential" [Curr Opin Microbiol 45 (2018) 61-69]. Current Opinion in Microbiology. PMID 31303539 DOI: 10.1016/J.Mib.2019.06.001 |
0.695 |
|
2019 |
Dong SH, Liu A, Mahanta N, Mitchell DA, Nair SK. Mechanistic Basis for Ribosomal Peptide Backbone Modifications. Acs Central Science. 5: 842-851. PMID 31139720 DOI: 10.1021/Acscentsci.9B00124 |
0.859 |
|
2019 |
Hudson GA, Burkhart BJ, DiCaprio AJ, Schwalen C, Kille B, Pogorelov TV, Mitchell DA. Bioinformatic mapping of radical SAM-dependent RiPPs identifies new Cα, Cβ, and Cγ-linked thioether-containing peptides. Journal of the American Chemical Society. PMID 31059252 DOI: 10.1021/Jacs.9B01519 |
0.823 |
|
2019 |
Mahanta N, Szantai-Kis DM, Petersson EJ, Mitchell DA. Biosynthesis and Chemical Applications of Thioamides. Acs Chemical Biology. PMID 30698414 DOI: 10.1021/Acschembio.8B01022 |
0.791 |
|
2018 |
DiCaprio AJ, Firouzbakht A, Hudson GA, Mitchell DA. Enzymatic Reconstitution and Biosynthetic Investigation of the Lasso Peptide Fusilassin. Journal of the American Chemical Society. PMID 30589265 DOI: 10.1021/Jacs.8B09928 |
0.86 |
|
2018 |
Hegemann JD, Schwalen CJ, Mitchell DA, van der Donk WA. Elucidation of the roles of conserved residues in the biosynthesis of the lasso peptide paeninodin. Chemical Communications (Cambridge, England). PMID 30046789 DOI: 10.1039/C8Cc04411B |
0.852 |
|
2018 |
Schwalen CJ, Hudson GA, Kille B, Mitchell DA. Bioinformatic expansion and discovery of thiopeptide antibiotics. Journal of the American Chemical Society. PMID 29983054 DOI: 10.1021/Jacs.8B03896 |
0.821 |
|
2018 |
Hudson GA, Mitchell DA. RiPP antibiotics: biosynthesis and engineering potential. Current Opinion in Microbiology. 45: 61-69. PMID 29533845 DOI: 10.1016/J.Mib.2018.02.010 |
0.791 |
|
2018 |
Mahanta N, Liu A, Dong S, Nair SK, Mitchell DA. Enzymatic reconstitution of ribosomal peptide backbone thioamidation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507203 DOI: 10.1073/Pnas.1722324115 |
0.853 |
|
2017 |
Schwalen CJ, Hudson GA, Kosol S, Mahanta N, Challis GL, Mitchell DA. In Vitro Biosynthetic Studies of Bottromycin Expand the Enzymatic Capabilities of the YcaO Superfamily. Journal of the American Chemical Society. 139: 18154-18157. PMID 29200283 DOI: 10.1021/Jacs.7B09899 |
0.855 |
|
2017 |
Zhang Z, Mahanta N, Hudson GA, Mitchell DA, van der Donk WA. Mechanism of a Class C Radical S-Adenosyl-l-methionine Thiazole Methyl Transferase. Journal of the American Chemical Society. PMID 29190095 DOI: 10.1021/Jacs.7B10203 |
0.783 |
|
2017 |
Cogan DP, Hudson GA, Zhang Z, Pogorelov TV, van der Donk WA, Mitchell DA, Nair SK. Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158402 DOI: 10.1073/Pnas.1716035114 |
0.81 |
|
2017 |
Mahanta N, Hudson GA, Mitchell DA. Correction to Radical S-Adenosylmethionine Enzymes Involved in RiPP Biosynthesis. Biochemistry. PMID 29094593 DOI: 10.1021/Acs.Biochem.7B01056 |
0.785 |
|
2017 |
Mahanta N, Hudson GA, Mitchell DA. Radical SAM enzymes involved in RiPP biosynthesis. Biochemistry. PMID 28895719 DOI: 10.1021/Acs.Biochem.7B00771 |
0.827 |
|
2017 |
Nayak DD, Mahanta N, Mitchell DA, Metcalf WW. Post-translational thioamidation of methyl-coenzyme M reductase, a key enzyme in methanogenic and methanotrophic Archaea. Elife. 6. PMID 28880150 DOI: 10.7554/Elife.29218 |
0.753 |
|
2017 |
Si T, Li B, Comi TJ, Wu Y, Hu P, Wu Y, Min Y, Mitchell DA, Zhao H, Sweedler JV. Profiling of microbial colonies for high-throughput engineering of multi-step enzymatic reactions via optically guided MALDI MS. Journal of the American Chemical Society. PMID 28792758 DOI: 10.1021/Jacs.7B04641 |
0.339 |
|
2017 |
Burkhart BJ, Kakkar N, Hudson GA, van der Donk WA, Mitchell DA. Chimeric Leader Peptides for the Generation of Non-Natural Hybrid RiPP Products. Acs Central Science. 3: 629-638. PMID 28691075 DOI: 10.1021/Acscentsci.7B00141 |
0.851 |
|
2017 |
Blin K, Wolf T, Chevrette MG, Lu X, Schwalen CJ, Kautsar SA, Suarez Duran HG, de Los Santos ELC, Kim HU, Nave M, Dickschat JS, Mitchell DA, Shelest E, Breitling R, Takano E, et al. antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification. Nucleic Acids Research. PMID 28460038 DOI: 10.1093/Nar/Gkx319 |
0.825 |
|
2017 |
Schwalen CJ, Feng X, Liu W, O-Dowd B, Ko TP, Shin CJ, Guo RT, Mitchell DA, Oldfield E. "Head-to-head" Prenyl Synthases in Some Pathogenic Bacteria. Chembiochem : a European Journal of Chemical Biology. PMID 28340291 DOI: 10.1002/Cbic.201700099 |
0.803 |
|
2017 |
Mahanta N, Zhang Z, Hudson GA, van der Donk WA, Mitchell DA. Reconstitution and substrate specificity of the radical SAM thiazole C-methyltransferase in thiomuracin biosynthesis. Journal of the American Chemical Society. PMID 28301141 DOI: 10.1021/Jacs.7B00693 |
0.832 |
|
2017 |
Burkhart BJ, Schwalen CJ, Mann G, Naismith JH, Mitchell DA. YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function. Chemical Reviews. PMID 28256131 DOI: 10.1021/Acs.Chemrev.6B00623 |
0.837 |
|
2017 |
Tietz JI, Schwalen CJ, Patel PS, Maxson T, Blair PM, Tai HC, Zakai UI, Mitchell DA. A new genome-mining tool redefines the lasso peptide biosynthetic landscape. Nature Chemical Biology. PMID 28244986 DOI: 10.1038/Nchembio.2319 |
0.849 |
|
2017 |
Nayak DD, Mahanta N, Mitchell DA, Metcalf WW. Author response: Post-translational thioamidation of methyl-coenzyme M reductase, a key enzyme in methanogenic and methanotrophic Archaea Elife. DOI: 10.7554/Elife.29218.024 |
0.714 |
|
2016 |
Maxson T, Tietz JI, Hudson GA, Guo XR, Tai HC, Mitchell DA. Targeting reactive carbonyls for identifying natural products and their biosynthetic origins. Journal of the American Chemical Society. PMID 27797509 DOI: 10.1021/Jacs.6B06848 |
0.802 |
|
2016 |
Zhang Z, Hudson GA, Mahanta N, Tietz JI, van der Donk WA, Mitchell DA. Biosynthetic timing and substrate specificity for the thiopeptide thiomuracin. Journal of the American Chemical Society. PMID 27700071 DOI: 10.1021/Jacs.6B08987 |
0.842 |
|
2016 |
Deane CD, Burkhart BJ, Blair PM, Tietz JI, Lin A, Mitchell DA. In vitro biosynthesis and substrate tolerance of the plantazolicin family of natural products. Acs Chemical Biology. PMID 27248686 DOI: 10.1021/Acschembio.6B00369 |
0.862 |
|
2016 |
Molloy EM, Tietz JI, Blair PM, Mitchell DA. Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products. Bioorganic & Medicinal Chemistry. PMID 27234886 DOI: 10.1016/J.Bmc.2016.05.021 |
0.393 |
|
2016 |
Molohon KJ, Blair PM, Park S, Doroghazi JR, Maxson T, Hershfield JR, Flatt KM, Schroeder NE, Ha T, Mitchell DA. Plantazolicin is an ultra-narrow spectrum antibiotic that targets the Bacillus anthracis membrane. Acs Infectious Diseases. 2: 207-220. PMID 27152321 DOI: 10.1021/Acsinfecdis.5B00115 |
0.337 |
|
2015 |
Hudson GA, Zhang Z, Tietz JI, Mitchell DA, van der Donk WA. In vitro biosynthesis of the core scaffold of the thiopeptide thiomuracin. Journal of the American Chemical Society. PMID 26675417 DOI: 10.1021/Jacs.5B10194 |
0.813 |
|
2015 |
Cox CL, Doroghazi JR, Mitchell DA. The genomic landscape of ribosomal peptides containing thiazole and oxazole heterocycles. Bmc Genomics. 16: 778. PMID 26462797 DOI: 10.1186/S12864-015-2008-0 |
0.579 |
|
2015 |
Tietz JI, Mitchell DA. Using Genomics for Natural Product Structure Elucidation. Current Topics in Medicinal Chemistry. PMID 26456468 DOI: 10.2174/1568026616666151012111439 |
0.368 |
|
2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Mitchell DA, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.451 |
|
2015 |
Molloy EM, Casjens SR, Cox CL, Maxson T, Ethridge NA, Margos G, Fingerle V, Mitchell DA. Identification of the minimal cytolytic unit for streptolysin S and an expansion of the toxin family. Bmc Microbiology. 15: 141. PMID 26204951 DOI: 10.1186/S12866-015-0464-Y |
0.344 |
|
2015 |
Burkhart BJ, Hudson GA, Dunbar KL, Mitchell DA. A prevalent peptide-binding domain guides ribosomal natural product biosynthesis. Nature Chemical Biology. PMID 26167873 DOI: 10.1038/Nchembio.1856 |
0.853 |
|
2015 |
Dunbar KL, Tietz JI, Cox CL, Burkhart BJ, Mitchell DA. Identification of an Auxiliary Leader Peptide-Binding Protein Required for Azoline Formation in Ribosomal Natural Products. Journal of the American Chemical Society. 137: 7672-7. PMID 26024319 DOI: 10.1021/Jacs.5B04682 |
0.833 |
|
2015 |
Maxson T, Deane CD, Molloy EM, Cox CL, Markley AL, Lee SW, Mitchell DA. HIV protease inhibitors block streptolysin S production. Acs Chemical Biology. 10: 1217-26. PMID 25668590 DOI: 10.1021/Cb500843R |
0.787 |
|
2015 |
Hao Y, Blair PM, Sharma A, Mitchell DA, Nair SK. Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin. Acs Chemical Biology. 10: 1209-16. PMID 25635336 DOI: 10.1021/Cb501042A |
0.645 |
|
2015 |
Metelev M, Tietz JI, Melby JO, Blair PM, Zhu L, Livnat I, Severinov K, Mitchell DA. Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso Peptide from an understudied halophilic actinomycete. Chemistry & Biology. 22: 241-50. PMID 25601074 DOI: 10.1016/J.Chembiol.2014.11.017 |
0.815 |
|
2015 |
Tietz J, Zhu L, Mitchell D, Metelev M, Melby J, Blair P, Livnat I, Severinov K. Solution-state NMR structure of the lasso peptide streptomonomicin Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Mw3/Pdb |
0.808 |
|
2014 |
Dunbar KL, Chekan JR, Cox CL, Burkhart BJ, Nair SK, Mitchell DA. Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis. Nature Chemical Biology. 10: 823-9. PMID 25129028 DOI: 10.1038/Nchembio.1608 |
0.806 |
|
2014 |
Zhang Q, Ortega M, Shi Y, Wang H, Melby JO, Tang W, Mitchell DA, van der Donk WA. Structural investigation of ribosomally synthesized natural products by hypothetical structure enumeration and evaluation using tandem MS. Proceedings of the National Academy of Sciences of the United States of America. 111: 12031-6. PMID 25092299 DOI: 10.1073/Pnas.1406418111 |
0.82 |
|
2014 |
Cox CL, Tietz JI, Sokolowski K, Melby JO, Doroghazi JR, Mitchell DA. Nucleophilic 1,4-additions for natural product discovery. Acs Chemical Biology. 9: 2014-22. PMID 24937678 DOI: 10.1021/Cb500324N |
0.807 |
|
2014 |
Hamel LD, Deschenes RJ, Mitchell DA. A fluorescence-based assay to monitor autopalmitoylation of zDHHC proteins applicable to high-throughput screening. Analytical Biochemistry. 460: 1-8. PMID 24878334 DOI: 10.1016/J.Ab.2014.05.013 |
0.647 |
|
2014 |
Mitchell DA, Hamel LD, Reddy KD, Farh L, Rettew LM, Sanchez PR, Deschenes RJ. Mutations in the X-linked intellectual disability gene, zDHHC9, alter autopalmitoylation activity by distinct mechanisms. The Journal of Biological Chemistry. 289: 18582-92. PMID 24811172 DOI: 10.1074/Jbc.M114.567420 |
0.642 |
|
2014 |
Melby JO, Li X, Mitchell DA. Orchestration of enzymatic processing by thiazole/oxazole-modified microcin dehydrogenases. Biochemistry. 53: 413-22. PMID 24364559 DOI: 10.1021/Bi401529Y |
0.816 |
|
2014 |
Deane CD, Mitchell DA. Lessons learned from the transformation of natural product discovery to a genome-driven endeavor. Journal of Industrial Microbiology & Biotechnology. 41: 315-31. PMID 24142337 DOI: 10.1007/S10295-013-1361-8 |
0.38 |
|
2013 |
Sharma A, Blair PM, Mitchell DA. Synthesis of plantazolicin analogues enables dissection of ligand binding interactions of a highly selective methyltransferase. Organic Letters. 15: 5076-9. PMID 24063702 DOI: 10.1021/Ol402444A |
0.513 |
|
2013 |
Lee J, Hao Y, Blair PM, Melby JO, Agarwal V, Burkhart BJ, Nair SK, Mitchell DA. Structural and functional insight into an unexpectedly selective N-methyltransferase involved in plantazolicin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 12954-9. PMID 23878226 DOI: 10.1073/Pnas.1306101110 |
0.806 |
|
2013 |
Deane CD, Melby JO, Molohon KJ, Susarrey AR, Mitchell DA. Engineering unnatural variants of plantazolicin through codon reprogramming. Acs Chemical Biology. 8: 1998-2008. PMID 23823732 DOI: 10.1021/Cb4003392 |
0.859 |
|
2013 |
Dunbar KL, Mitchell DA. Insights into the mechanism of peptide cyclodehydrations achieved through the chemoenzymatic generation of amide derivatives. Journal of the American Chemical Society. 135: 8692-701. PMID 23721104 DOI: 10.1021/Ja4029507 |
0.553 |
|
2013 |
Hu Y, Jia S, Ren F, Huang CH, Ko TP, Mitchell DA, Guo RT, Zheng Y. Crystallization and preliminary X-ray diffraction analysis of YisP protein from Bacillus subtilis subsp. subtilis strain 168. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 77-9. PMID 23295493 DOI: 10.1107/S1744309112049330 |
0.31 |
|
2013 |
Dunbar KL, Mitchell DA. Revealing nature's synthetic potential through the study of ribosomal natural product biosynthesis. Acs Chemical Biology. 8: 473-87. PMID 23286465 DOI: 10.1021/Cb3005325 |
0.559 |
|
2013 |
Zhu W, Zhang Y, Sinko W, Hensler ME, Olson J, Molohon KJ, Lindert S, Cao R, Li K, Wang K, Wang Y, Liu YL, Sankovsky A, de Oliveira CA, Mitchell DA, et al. Antibacterial drug leads targeting isoprenoid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 123-8. PMID 23248302 DOI: 10.1073/Pnas.1219899110 |
0.331 |
|
2013 |
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... ... Mitchell DA, et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. 30: 108-60. PMID 23165928 DOI: 10.1039/C2Np20085F |
0.614 |
|
2013 |
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... ... Mitchell DA, et al. Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F) Natural Product Reports. 30: 1568-1568. DOI: 10.1039/C3Np90040A |
0.606 |
|
2013 |
Dunbar KL, Mitchell DA. Correction to Revealing Nature’s Synthetic Potential through the Study of Ribosomal Natural Product Biosynthesis Acs Chemical Biology. 8: 1083-1083. DOI: 10.1021/Cb4002359 |
0.381 |
|
2012 |
Mitchell DA, Hamel LD, Ishizuka K, Mitchell G, Schaefer LM, Deschenes RJ. The Erf4 subunit of the yeast Ras palmitoyl acyltransferase is required for stability of the Acyl-Erf2 intermediate and palmitoyl transfer to a Ras2 substrate. The Journal of Biological Chemistry. 287: 34337-48. PMID 22904317 DOI: 10.1074/Jbc.M112.379297 |
0.64 |
|
2012 |
Dunbar KL, Melby JO, Mitchell DA. YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations. Nature Chemical Biology. 8: 569-75. PMID 22522320 DOI: 10.1038/Nchembio.944 |
0.845 |
|
2012 |
Melby JO, Dunbar KL, Trinh NQ, Mitchell DA. Selectivity, directionality, and promiscuity in peptide processing from a Bacillus sp. Al Hakam cyclodehydratase. Journal of the American Chemical Society. 134: 5309-16. PMID 22401305 DOI: 10.1021/Ja211675N |
0.846 |
|
2011 |
Molohon KJ, Melby JO, Lee J, Evans BS, Dunbar KL, Bumpus SB, Kelleher NL, Mitchell DA. Structure determination and interception of biosynthetic intermediates for the plantazolicin class of highly discriminating antibiotics. Acs Chemical Biology. 6: 1307-13. PMID 21950656 DOI: 10.1021/Cb200339D |
0.833 |
|
2011 |
Molloy EM, Cotter PD, Hill C, Mitchell DA, Ross RP. Streptolysin S-like virulence factors: the continuing sagA. Nature Reviews. Microbiology. 9: 670-81. PMID 21822292 DOI: 10.1038/Nrmicro2624 |
0.435 |
|
2011 |
Pei J, Mitchell DA, Dixon JE, Grishin NV. Expansion of type II CAAX proteases reveals evolutionary origin of γ-secretase subunit APH-1. Journal of Molecular Biology. 410: 18-26. PMID 21570408 DOI: 10.1016/J.Jmb.2011.04.066 |
0.533 |
|
2011 |
Melby JO, Nard NJ, Mitchell DA. Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates. Current Opinion in Chemical Biology. 15: 369-78. PMID 21429787 DOI: 10.1016/J.Cbpa.2011.02.027 |
0.825 |
|
2011 |
Scholz R, Molohon KJ, Nachtigall J, Vater J, Markley AL, Süssmuth RD, Mitchell DA, Borriss R. Plantazolicin, a novel microcin B17/streptolysin S-like natural product from Bacillus amyloliquefaciens FZB42. Journal of Bacteriology. 193: 215-24. PMID 20971906 DOI: 10.1128/Jb.00784-10 |
0.804 |
|
2010 |
Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. The Journal of Biological Chemistry. 285: 28220-8. PMID 20581111 DOI: 10.1074/Jbc.M110.118554 |
0.786 |
|
2010 |
Haft DH, Basu MK, Mitchell DA. Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family. Bmc Biology. 8: 70. PMID 20500830 DOI: 10.1186/1741-7007-8-70 |
0.566 |
|
2009 |
Mitchell DA, Lee SW, Pence MA, Markley AL, Limm JD, Nizet V, Dixon JE. Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S. The Journal of Biological Chemistry. 284: 13004-12. PMID 19286651 DOI: 10.1074/Jbc.M900802200 |
0.853 |
|
2008 |
Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. Discovery of a widely distributed toxin biosynthetic gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 105: 5879-84. PMID 18375757 DOI: 10.1073/Pnas.0801338105 |
0.863 |
|
2007 |
Mitchell DA, Morton SU, Fernhoff NB, Marletta MA. Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 11609-14. PMID 17606900 DOI: 10.1073/Pnas.0704898104 |
0.778 |
|
2007 |
Mitchell DA, Michel T, Marletta MA. Effects of S-nitrosation of nitric oxide synthase Advances in Experimental Biology. 1: 151-179,456. DOI: 10.1016/S1872-2423(07)01007-1 |
0.41 |
|
2006 |
Mitchell DA, Morton SU, Marletta MA. Design and characterization of an active site selective caspase-3 transnitrosating agent. Acs Chemical Biology. 1: 659-65. PMID 17168570 DOI: 10.1021/Cb600393X |
0.515 |
|
2006 |
Erwin PA, Mitchell DA, Sartoretto J, Marletta MA, Michel T. Subcellular targeting and differential S-nitrosylation of endothelial nitric-oxide synthase. The Journal of Biological Chemistry. 281: 151-7. PMID 16286475 DOI: 10.1074/Jbc.M510421200 |
0.514 |
|
2005 |
Mitchell DA, Marletta MA. Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine. Nature Chemical Biology. 1: 154-8. PMID 16408020 DOI: 10.1038/Nchembio720 |
0.558 |
|
2005 |
Mitchell DA, Erwin PA, Michel T, Marletta MA. S-Nitrosation and regulation of inducible nitric oxide synthase. Biochemistry. 44: 4636-47. PMID 15779890 DOI: 10.1021/Bi0474463 |
0.499 |
|
2002 |
Lazo JS, Nemoto K, Pestell KE, Cooley K, Southwick EC, Mitchell DA, Furey W, Gussio R, Zaharevitz DW, Joo B, Wipf P. Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors. Molecular Pharmacology. 61: 720-8. PMID 11901209 DOI: 10.1124/Mol.61.4.720 |
0.358 |
|
1995 |
Farh L, Mitchell DA, Deschenes RJ. Farnesylation and proteolysis are sequential, but distinct steps in the CaaX box modification pathway. Archives of Biochemistry and Biophysics. 318: 113-21. PMID 7726551 DOI: 10.1006/Abbi.1995.1211 |
0.712 |
|
1993 |
Mitchell DA, Marshall TK, Deschenes RJ. Vectors for the inducible overexpression of glutathione S-transferase fusion proteins in yeast Yeast. 9: 715-722. PMID 8368005 DOI: 10.1002/Yea.320090705 |
0.606 |
|
Show low-probability matches. |