| Year |
Citation |
Score |
| 2024 |
Atkinson R, Georgiou M, Yang C, Szymanska K, Lahat A, Vasconcelos EJR, Ji Y, Moya Molina M, Collin J, Queen R, Dorgau B, Watson A, Kurzawa-Akanbi M, Laws R, Saxena A, ... ... Ali RR, et al. PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects. Nature Communications. 15: 3138. PMID 38605034 DOI: 10.1038/s41467-024-47253-0 |
0.363 |
|
| 2024 |
Kalargyrou AA, Matsuyama A, Lanning EP, Khazim M, Guilfoyle S, Smith AJ, Ali RR, Pearson RA. A protocol for isolation and culturing of mouse primary postmitotic photoreceptors and isolation of extracellular vesicles. Star Protocols. 5: 102875. PMID 38386547 DOI: 10.1016/j.xpro.2024.102875 |
0.48 |
|
| 2023 |
Cristante E, Liyanage SE, Smith AJ, Ali RR, Bainbridge JWB. Role of Hif1a and Hif2a in Cre recombinase-induced retinal pigment epithelium pathology and its secondary effect on choroidal neovascularisation. The American Journal of Pathology. PMID 37330004 DOI: 10.1016/j.ajpath.2023.05.017 |
0.327 |
|
| 2023 |
Awadh Hashem S, Georgiou M, Ali RR, Michaelides M. -Related Retinopathy: Clinical Features, Molecular Genetics, and Gene Replacement Therapy. Cold Spring Harbor Perspectives in Medicine. PMID 37188525 DOI: 10.1101/cshperspect.a041280 |
0.307 |
|
| 2023 |
Feathers KL, Jia L, Khan NW, Smith A, Ma JX, Ali RR, Thompson DA. Gene Supplementation in Mice Heterozygous for the D477G-RPE65 Variant Implicated in Autosomal Dominant Retinitis Pigmentosa. Human Gene Therapy. PMID 37014074 DOI: 10.1089/hum.2022.240 |
0.368 |
|
| 2023 |
Kalargyrou AA, Guilfoyle SE, Smith AJ, Ali RR, Pearson RA. Extracellular vesicles in the retina - putative roles in physiology and disease. Frontiers in Molecular Neuroscience. 15: 1042469. PMID 36710933 DOI: 10.3389/fnmol.2022.1042469 |
0.62 |
|
| 2022 |
Fernando M, Lee S, Wark JR, Xiao D, Lim BY, O'Hara-Wright M, Kim HJ, Smith GC, Wong T, Teber ET, Ali RR, Yang P, Graham ME, Gonzalez-Cordero A. Differentiation of brain and retinal organoids from confluent cultures of pluripotent stem cells connected by nerve-like axonal projections of optic origin. Stem Cell Reports. PMID 35523177 DOI: 10.1016/j.stemcr.2022.04.003 |
0.35 |
|
| 2022 |
Fort PE, Losiewicz MK, Elghazi L, Kong D, Cras-Méneur C, Fingar DC, Kimball SR, Rajala RVS, Smith AJ, Ali RR, Abcouwer SF, Gardner TW. mTORC1 Regulates High Levels of Protein Synthesis in Retinal Ganglion Cells of Adult Mice. The Journal of Biological Chemistry. 101944. PMID 35447116 DOI: 10.1016/j.jbc.2022.101944 |
0.377 |
|
| 2022 |
West EL, Majunder P, Naeem A, Fernando M, O'Hara-Wright M, Lanning E, Kloc M, Ribeiro J, Ovando-Roche P, Shum IO, Jumbu N, Sampson R, Hayes M, Bainbridge JWB, Georgiadis A, ... ... Ali RR, et al. Antioxidant and lipid supplementation improve the development of photoreceptor outer segments in pluripotent stem cell-derived retinal organoids. Stem Cell Reports. PMID 35334217 DOI: 10.1016/j.stemcr.2022.02.019 |
0.498 |
|
| 2022 |
Georgiou M, Yang C, Atkinson R, Pan KT, Buskin A, Molina MM, Collin J, Al-Aama J, Goertler F, Ludwig SEJ, Davey T, Lührmann R, Nagaraja-Grellscheid S, Johnson CA, Ali R, et al. Activation of autophagy reverses progressive and deleterious protein aggregation in PRPF31 patient-induced pluripotent stem cell-derived retinal pigment epithelium cells. Clinical and Translational Medicine. 12: e759. PMID 35297555 DOI: 10.1002/ctm2.759 |
0.401 |
|
| 2021 |
Klaska IP, White A, Villacampa P, Hoke J, Hervás LA, Maswood RN, Ali RR, Bunce C, Unwin RD, Cooper GJS, Bishop PN, Bainbridge JW. Intravitreal administration of recombinant human opticin protects against hyperoxia-induced pre-retinal neovascularization. Experimental Eye Research. 108908. PMID 34954204 DOI: 10.1016/j.exer.2021.108908 |
0.366 |
|
| 2021 |
Aghaizu ND, Warre-Cornish KM, Robinson MR, Ali RR, Pearson RA. Tracking neuronal motility in live murine retinal explants. Star Protocols. 2: 101008. PMID 34917982 DOI: 10.1016/j.xpro.2021.101008 |
0.814 |
|
| 2021 |
Kalargyrou AA, Basche M, Hare A, West EL, Smith AJ, Ali RR, Pearson RA. Nanotube-like processes facilitate material transfer between photoreceptors. Embo Reports. e53732. PMID 34494703 DOI: 10.15252/embr.202153732 |
0.534 |
|
| 2021 |
Yang C, Georgiou M, Atkinson R, Collin J, Al-Aama J, Nagaraja-Grellscheid S, Johnson C, Ali R, Armstrong L, Mozaffari-Jovin S, Lako M. Pre-mRNA Processing Factors and Retinitis Pigmentosa: RNA Splicing and Beyond. Frontiers in Cell and Developmental Biology. 9: 700276. PMID 34395430 DOI: 10.3389/fcell.2021.700276 |
0.414 |
|
| 2021 |
Aghaizu ND, Warre-Cornish KM, Robinson MR, Waldron PV, Maswood RN, Smith AJ, Ali RR, Pearson RA. Repeated nuclear translocations underlie photoreceptor positioning and lamination of the outer nuclear layer in the mammalian retina. Cell Reports. 36: 109461. PMID 34348137 DOI: 10.1016/j.celrep.2021.109461 |
0.757 |
|
| 2021 |
Hippert C, Graca AB, Basche M, Kalargyrou AA, Georgiadis A, Ribeiro J, Matsuyama A, Aghaizu N, Bainbridge JW, Smith AJ, Ali RR, Pearson RA. RNAi-mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Müller glial cell hypertrophy in progressive retinal degeneration. Glia. PMID 34029407 DOI: 10.1002/glia.24034 |
0.806 |
|
| 2021 |
Ribeiro J, Procyk CA, West EL, O'Hara-Wright M, Martins MF, Khorasani MM, Hare A, Basche M, Fernando M, Goh D, Jumbo N, Rizzi M, Powell K, Tariq M, Michaelides M, ... ... Ali RR, et al. Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors. Cell Reports. 35: 109022. PMID 33882303 DOI: 10.1016/j.celrep.2021.109022 |
0.705 |
|
| 2021 |
Annear MJ, Mowat FM, Occelli LM, Smith AJ, Curran PG, Bainbridge JW, Ali RR, Petersen-Jones SM. A Comprehensive Study of the Retinal Phenotype of Rpe65-Deficient Dogs. Cells. 10. PMID 33435495 DOI: 10.3390/cells10010115 |
0.433 |
|
| 2020 |
Kumaran N, Ali RR, Tyler NA, Bainbridge JWB, Michaelides M, Rubin GS. Validation of a Vision-Guided Mobility Assessment for -Associated Retinal Dystrophy. Translational Vision Science & Technology. 9: 5. PMID 32953245 DOI: 10.1167/tvst.9.10.5 |
0.34 |
|
| 2020 |
Kleine Holthaus SM, Aristorena M, Maswood R, Semenyuk O, Hoke J, Hare A, Smith AJ, Mole SE, Ali RR. Gene therapy targeting the inner retina rescues the retinal phenotype in a mouse model of CLN3 Batten disease. Human Gene Therapy. PMID 32578444 DOI: 10.1089/Hum.2020.038 |
0.47 |
|
| 2020 |
Aguilà M, Bellingham J, Athanasiou D, Bevilacqua D, Duran Y, Maswood R, Parfitt DA, Iwawaki T, Spyrou G, Smith AJ, Ali RR, Cheetham ME. AAV-mediated ERdj5 overexpression protects against P23H rhodopsin toxicity. Human Molecular Genetics. PMID 32196553 DOI: 10.1093/hmg/ddaa049 |
0.313 |
|
| 2020 |
Kumaran N, Ali RR, Tyler NA, Bainbridge JWB, Michaelides M, Rubin GS. Validation of a Vision-Guided Mobility Assessment for RPE65-Associated Retinal Dystrophy Translational Vision Science & Technology. 9: 5. DOI: 10.1167/tvst.9.10.5 |
0.355 |
|
| 2019 |
West EL, Ribeiro J, Ali RR. Development of Stem Cell Therapies for Retinal Degeneration. Cold Spring Harbor Perspectives in Biology. PMID 31818854 DOI: 10.1101/cshperspect.a035683 |
0.537 |
|
| 2019 |
Villacampa P, Liyanage SE, Klaska IP, Cristante E, Menger KE, Sampson RD, Barlow M, Abelleira-Hervas L, Duran Y, Smith AJ, Ali RR, Luhmann UFO, Bainbridge JWB. Stabilization of myeloid-derived HIFs promotes vascular regeneration in retinal ischemia. Angiogenesis. PMID 31583505 DOI: 10.1007/s10456-019-09681-1 |
0.404 |
|
| 2019 |
Kampik D, Basche M, Georgiadis A, Luhmann UFO, Larkin DF, Smith AJ, Ali RR. Modulation of Contact Inhibition by ZO-1/ZONAB Gene Transfer-A New Strategy to Increase the Endothelial Cell Density of Corneal Grafts. Investigative Ophthalmology & Visual Science. 60: 3170-3177. PMID 31335954 DOI: 10.1167/iovs.18-26260 |
0.308 |
|
| 2019 |
Feathers KL, Jia L, Perera ND, Chen A, Presswalla FK, Khan NW, Fahim AT, Smith AJ, Ali RR, Thompson DA. Development of a gene-therapy vector for RDH12-associated retinal dystrophy. Human Gene Therapy. PMID 31237438 DOI: 10.1089/hum.2019.017 |
0.454 |
|
| 2019 |
Fahim AT, Bouzia Z, Branham KH, Kumaran N, Vargas ME, Feathers KL, Perera ND, Young K, Khan NW, Heckenlively JR, Webster AR, Pennesi ME, Ali RR, Thompson DA, Michaelides M. Detailed clinical characterisation, unique features and natural history of autosomal recessive -associated retinal degeneration. The British Journal of Ophthalmology. PMID 30979730 DOI: 10.1136/bjophthalmol-2018-313580 |
0.376 |
|
| 2019 |
Aldunate EZ, Di Foggia V, Di Marco F, Hervas LA, Ribeiro JC, Holder DL, Patel A, Jannini TB, Thompson DA, Martinez-Barbera JP, Pearson RA, Ali RR, Sowden JC. Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision. Scientific Reports. 9: 2314. PMID 30783126 DOI: 10.1038/s41598-018-38294-9 |
0.791 |
|
| 2019 |
Cayouette M, Javed A, Mattar P, Kruczek K, Lu S, Kloc M, Gonzalez-Cordero A, Bremner R, Ali R. Transcriptional regulation of cone photoreceptor development Ibro Reports. 6: S20-S21. DOI: 10.1016/J.Ibror.2019.07.052 |
0.345 |
|
| 2018 |
Pearson RA, Ali RR. Unlocking the Potential for Endogenous Repair to Restore Sight. Neuron. 100: 524-526. PMID 30408440 DOI: 10.1016/j.neuron.2018.10.035 |
0.479 |
|
| 2018 |
Buskin A, Zhu L, Chichagova V, Basu B, Mozaffari-Jovin S, Dolan D, Droop A, Collin J, Bronstein R, Mehrotra S, Farkas M, Hilgen G, White K, Pan KT, Treumann A, ... ... Ali RR, et al. Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa. Nature Communications. 9: 4234. PMID 30315276 DOI: 10.1038/S41467-018-06448-Y |
0.402 |
|
| 2018 |
Basche M, Kampik D, Kawasaki S, Branch MJ, Robinson M, Larkin F, Smith AJ, Ali RR. Sustained and widespread gene delivery to the corneal epithelium via in situ transduction of limbal epithelial stem cells using lentiviral and AAV vectors. Human Gene Therapy. PMID 30070149 DOI: 10.1089/hum.2018.115 |
0.324 |
|
| 2018 |
Ovando-Roche P, West EL, Branch MJ, Sampson RD, Fernando M, Munro P, Georgiadis A, Rizzi M, Kloc M, Naeem A, Ribeiro J, Smith AJ, Gonzalez-Cordero A, Ali RR. Use of bioreactors for culturing human retinal organoids improves photoreceptor yields. Stem Cell Research & Therapy. 9: 156. PMID 29895313 DOI: 10.1186/s13287-018-0907-0 |
0.497 |
|
| 2018 |
Mehat MS, Sundaram V, Ripamonti C, Robson AG, Smith AJ, Borooah S, Robinson M, Rosenthal AN, Innes W, Weleber RG, Lee RWJ, Crossland M, Rubin GS, Dhillon B, Steel DHW, ... ... Ali RR, et al. Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in Macular Degeneration. Ophthalmology. PMID 29884405 DOI: 10.1016/j.ophtha.2018.04.037 |
0.558 |
|
| 2018 |
Stern JH, Tian Y, Funderburgh J, Pellegrini G, Zhang K, Goldberg JL, Ali RR, Young M, Xie Y, Temple S. Regenerating Eye Tissues to Preserve and Restore Vision. Cell Stem Cell. 22: 834-849. PMID 29859174 DOI: 10.1016/J.Stem.2018.05.013 |
0.453 |
|
| 2018 |
Cristante E, Liyanage SE, Sampson RD, Kalargyrou A, De Rossi G, Rizzi M, Hoke J, Ribeiro J, Maswood RN, Duran Y, Matsuki T, Aghaizu N, Luhmann UF, Smith AJ, Ali RR, et al. Late neuroprogenitors contribute to normal retinal vascular development in a-dependent manner. Development (Cambridge, England). PMID 29615467 DOI: 10.1242/dev.157511 |
0.83 |
|
| 2018 |
Kleine Holthaus SM, Ribeiro J, Abelleira-Hervas L, Pearson RA, Duran Y, Georgiadis A, Sampson RD, Rizzi M, Hoke J, Maswood R, Azam S, Luhmann UFO, Smith AJ, Mole SE, Ali RR. Prevention of Photoreceptor Cell Loss in a Cln6Mouse Model of Batten Disease Requires CLN6 Gene Transfer to Bipolar Cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29606505 DOI: 10.1016/J.Ymthe.2018.02.027 |
0.622 |
|
| 2018 |
Gonzalez Cordero A, Goh D, Kruczek K, Naeem A, Fernando M, Kleine Holthaus SM, Takaaki M, Blackford SJI, Kloc M, Agundez L, Sampson RD, Borooah S, Ovando-Roche P, Mehat MS, West EL, ... ... Ali RR, et al. Assessment of AAV vector tropisms for mouse and human pluripotent stem cell-derived RPE and photoreceptor cells. Human Gene Therapy. PMID 29580100 DOI: 10.1089/Hum.2018.027 |
0.597 |
|
| 2018 |
Kumaran N, Michaelides M, Smith AJ, Ali RR, Bainbridge JWB. Retinal gene therapy. British Medical Bulletin. PMID 29506236 DOI: 10.1093/bmb/ldy005 |
0.317 |
|
| 2018 |
Lakowski J, Welby E, Budinger D, Di Marco F, Di Foggia V, Bainbridge JWB, Wallace K, Gamm DM, Ali RR, Sowden JC. Isolation of Human Photoreceptor Precursors via a Cell Surface Marker Panel from Stem Cell-derived Retinal Organoids and Fetal Retinae. Stem Cells (Dayton, Ohio). PMID 29327488 DOI: 10.1002/stem.2775 |
0.723 |
|
| 2018 |
Waldron PV, Di Marco F, Kruczek K, Ribeiro J, Graca AB, Hippert C, Aghaizu ND, Kalargyrou AA, Barber AC, Grimaldi G, Duran Y, Blackford SJI, Kloc M, Goh D, Zabala Aldunate E, ... ... Ali RR, et al. Transplanted Donor- or Stem Cell-Derived Cone Photoreceptors Can Both Integrate and Undergo Material Transfer in an Environment-Dependent Manner. Stem Cell Reports. PMID 29307580 DOI: 10.1016/J.Stemcr.2017.12.008 |
0.766 |
|
| 2018 |
Kumaran N, Smith AJ, Michaelides M, Ali R, Bainbridge J. Gene therapy for Leber congenital amaurosis Expert Review of Ophthalmology. 13: 11-15. DOI: 10.1080/17469899.2018.1429916 |
0.348 |
|
| 2017 |
Kampik D, Basche M, Luhmann UFO, Nishiguchi KM, Williams JAE, Greenwood J, Moss SE, Han H, Azam S, Duran Y, Robbie SJ, Bainbridge JWB, Larkin DF, Smith AJ, Ali RR. In situ regeneration of retinal pigment epithelium by gene transfer of E2F2: a potential strategy for treatment of macular degenerations. Gene Therapy. PMID 29188796 DOI: 10.1038/gt.2017.89 |
0.512 |
|
| 2017 |
Welby E, Lakowski J, Di Foggia V, Budinger D, Gonzalez-Cordero A, Lun ATL, Epstein M, Patel A, Cuevas E, Kruczek K, Naeem A, Minneci F, Hubank M, Jones DT, Marioni JC, ... Ali RR, et al. Isolation and Comparative Transcriptome Analysis of Human Fetal and iPSC-Derived Cone Photoreceptor Cells. Stem Cell Reports. PMID 29153988 DOI: 10.1016/j.stemcr.2017.10.018 |
0.746 |
|
| 2017 |
Fanelli G, Gonzalez-Cordero A, Gardner PJ, Peng Q, Fernando M, Kloc M, Farrar CA, Naeem A, Garred P, Ali RR, Sacks SH. Human stem cell-derived retinal epithelial cells activate complement via collectin 11 in response to stress. Scientific Reports. 7: 14625. PMID 29116192 DOI: 10.1038/s41598-017-15212-z |
0.381 |
|
| 2017 |
Gonzalez-Cordero A, Kruczek K, Naeem A, Fernando M, Kloc M, Ribeiro J, Goh D, Duran Y, Blackford SJI, Abelleira-Hervas L, Sampson RD, Shum IO, Branch MJ, Gardner PJ, Sowden JC, ... ... Ali RR, et al. Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors. Stem Cell Reports. PMID 28844659 DOI: 10.1016/J.Stemcr.2017.07.022 |
0.806 |
|
| 2017 |
Ali RR, Auricchio A, Smith AJ. The future looks brighter after 25 years of retinal gene therapy. Human Gene Therapy. PMID 28825330 DOI: 10.1089/Hum.2017.164 |
0.373 |
|
| 2017 |
Mowat FM, Gervais KJ, Occelli LM, Annear MJ, Querubin J, Bainbridge JW, Smith AJ, Ali RR, Petersen-Jones SM. Early-Onset Progressive Degeneration of the Area Centralis in RPE65-Deficient Dogs. Investigative Ophthalmology & Visual Science. 58: 3268-3277. PMID 28662231 DOI: 10.1167/iovs.17-21930 |
0.413 |
|
| 2017 |
Villacampa P, Menger KE, Abelleira L, Ribeiro J, Duran Y, Smith AJ, Ali RR, Luhmann UF, Bainbridge JWB. Accelerated oxygen-induced retinopathy is a reliable model of ischemia-induced retinal neovascularization. Plos One. 12: e0179759. PMID 28650964 DOI: 10.1371/journal.pone.0179759 |
0.374 |
|
| 2017 |
Ovando-Roche P, Georgiadis A, Smith AJ, Pearson RA, Ali RR. Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration. Current Stem Cell Reports. 3: 112-123. PMID 28596937 DOI: 10.1007/s40778-017-0078-4 |
0.645 |
|
| 2017 |
Aghaizu ND, Kruczek K, Gonzalez-Cordero A, Ali RR, Pearson RA. Pluripotent stem cells and their utility in treating photoreceptor degenerations. Progress in Brain Research. 231: 191-223. PMID 28554397 DOI: 10.1016/bs.pbr.2017.01.001 |
0.852 |
|
| 2017 |
Kruczek K, Gonzalez-Cordero A, Goh D, Naeem A, Jonikas M, Blackford SJI, Kloc M, Duran Y, Georgiadis A, Sampson RD, Maswood RN, Smith AJ, Decembrini S, Arsenijevic Y, Sowden JC, ... ... Ali RR, et al. Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration. Stem Cell Reports. PMID 28552606 DOI: 10.1016/J.Stemcr.2017.04.030 |
0.809 |
|
| 2017 |
Gardner PJ, Liyanage SE, Cristante E, Sampson RD, Dick AD, Ali RR, Bainbridge JW. Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye. Scientific Reports. 7: 40830. PMID 28112274 DOI: 10.1038/srep40830 |
0.308 |
|
| 2017 |
Athanasiou D, Aguila M, Opefi CA, South K, Bellingham J, Bevilacqua D, Munro PM, Kanuga N, Mackenzie FE, Dubis AM, Georgiadis A, Graca AB, Pearson RA, Ali RR, Sakami S, et al. Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration. Human Molecular Genetics. PMID 28065882 DOI: 10.1093/Hmg/Ddw387 |
0.79 |
|
| 2016 |
Downs LM, Webster AR, Moore AT, Michaelides M, Ali RR, Hardcastle AJ, Mellersh CS. Investigation of SLA4A3 as a candidate gene for human retinal disease. Journal of Negative Results in Biomedicine. 15: 11. PMID 27211793 DOI: 10.1186/s12952-016-0054-z |
0.397 |
|
| 2016 |
Lange C, Mowat F, Sayed H, Mehad M, Duluc L, Piper S, Luhmann U, Nandi M, Kelly P, Smith A, Ali R, Leiper J, Bainbridge J. Dimethylarginine dimethylaminohydrolase-2 deficiency promotes vascular regeneration and attenuates pathological angiogenesis. Experimental Eye Research. PMID 27181226 DOI: 10.1016/J.Exer.2016.05.007 |
0.457 |
|
| 2016 |
Di Foggia V, Makwana P, Ali RR, Sowden JC. Induced Pluripotent Stem Cell Therapies for Degenerative Disease of the Outer Retina: Disease Modeling and Cell Replacement. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 27027805 DOI: 10.1089/jop.2015.0143 |
0.745 |
|
| 2016 |
Luhmann U, Kampik D, Nishiguchi K, Basche M, Smith A, Ali R. Gene transfer of E2F2 induces in situ regeneration of retinal pigment epithelium Acta Ophthalmologica. 94. DOI: 10.1111/j.1755-3768.2016.0159 |
0.359 |
|
| 2016 |
Henckaerts E, Tordo J, Palomar N, Rahman J, Aldrin-Kirk P, Basche M, Bennett A, O'Leary C, Ali R, Agbandje-McKenna M, Bigger B, Rahim AA, Björklund T, Waddington S, Linden RM. 256. A Novel Rationally Designed AAV Capsid Yields a Potent Neurotropic Gene Therapy Vector Molecular Therapy. 24: S101. DOI: 10.1016/S1525-0016(16)33065-9 |
0.348 |
|
| 2016 |
Fanelli G, Gardner P, Gonzalez-Cordero A, Qi P, Farrar C, Naeem A, Milan F, Ali R, Sacks S. Collectin 11 expression by hypoxia-stressed iPSC-derived RPE cells is linked to complement activation Immunobiology. 221: 1178. DOI: 10.1016/J.Imbio.2016.06.121 |
0.336 |
|
| 2015 |
Ripamonti C, Henning GB, Robbie SJ, Sundaram V, van den Born LI, Casteels I, de Ravel TJ, Moore AT, Smith AJ, Bainbridge JW, Ali RR, Stockman A. Spectral sensitivity measurements reveal partial success in restoring missing rod function with gene therapy. Journal of Vision. 15: 20. PMID 26605849 DOI: 10.1167/15.15.20 |
0.323 |
|
| 2015 |
Herrmann P, Cowing JA, Cristante E, Liyanage SE, Ribeiro J, Duran Y, Abelleira Hervas L, Carvalho LS, Bainbridge JW, Luhmann UF, Ali RR. Cd59a deficiency in mice leads to preferential innate immune activation in the retinal pigment epithelium-choroid with age. Neurobiology of Aging. 36: 2637-48. PMID 26234657 DOI: 10.1016/j.neurobiolaging.2015.05.019 |
0.364 |
|
| 2015 |
Lakowski J, Gonzalez-Cordero A, West EL, Han YT, Welby E, Naeem A, Blackford SJ, Bainbridge JW, Pearson RA, Ali RR, Sowden JC. Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell-Derived Self-Forming Retina. Stem Cells (Dayton, Ohio). 33: 2469-82. PMID 25982268 DOI: 10.1002/stem.2051 |
0.777 |
|
| 2015 |
Hippert C, Graca AB, Barber AC, West EL, Smith AJ, Ali RR, Pearson RA. Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific. Plos One. 10: e0120415. PMID 25793273 DOI: 10.1371/journal.pone.0120415 |
0.802 |
|
| 2015 |
Thompson DA, Ali RR, Banin E, Branham KE, Flannery JG, Gamm DM, Hauswirth WW, Heckenlively JR, Iannaccone A, Jayasundera KT, Khan NW, Molday RS, Pennesi ME, Reh TA, Weleber RG, et al. Advancing therapeutic strategies for inherited retinal degeneration: recommendations from the Monaciano Symposium. Investigative Ophthalmology & Visual Science. 56: 918-31. PMID 25667399 DOI: 10.1167/Iovs.14-16049 |
0.382 |
|
| 2015 |
Jayakody SA, Gonzalez-Cordero A, Ali RR, Pearson RA. Cellular strategies for retinal repair by photoreceptor replacement. Progress in Retinal and Eye Research. 46: 31-66. PMID 25660226 DOI: 10.1016/j.preteyeres.2015.01.003 |
0.708 |
|
| 2015 |
Luhmann UF, Carvalho LS, Holthaus SM, Cowing JA, Greenaway S, Chu CJ, Herrmann P, Smith AJ, Munro PM, Potter P, Bainbridge JW, Ali RR. The severity of retinal pathology in homozygous Crb1rd8/rd8 mice is dependent on additional genetic factors. Human Molecular Genetics. 24: 128-41. PMID 25147295 DOI: 10.1093/hmg/ddu424 |
0.332 |
|
| 2014 |
Ripamonti C, Henning GB, Ali RR, Bainbridge JW, Robbie SJ, Sundaram V, Luong VA, van den Born LI, Casteels I, de Ravel TJ, Moore AT, Stockman A. Nature of the visual loss in observers with Leber's congenital amaurosis caused by specific mutations in RPE65. Investigative Ophthalmology & Visual Science. 55: 6817-28. PMID 25257057 DOI: 10.1167/Iovs.14-14923 |
0.306 |
|
| 2014 |
Luhmann UF, Robbie SJ, Bainbridge JW, Ali RR. The relevance of chemokine signalling in modulating inherited and age-related retinal degenerations. Advances in Experimental Medicine and Biology. 801: 427-33. PMID 24664727 DOI: 10.1007/978-1-4614-3209-8_54 |
0.332 |
|
| 2014 |
Warre-Cornish K, Barber AC, Sowden JC, Ali RR, Pearson RA. Migration, integration and maturation of photoreceptor precursors following transplantation in the mouse retina. Stem Cells and Development. 23: 941-54. PMID 24328605 DOI: 10.1089/Scd.2013.0471 |
0.831 |
|
| 2014 |
Sundaram V, Wilde C, Aboshiha J, Cowing J, Han C, Langlo CS, Chana R, Davidson AE, Sergouniotis PI, Bainbridge JW, Ali RR, Dubra A, Rubin G, Webster AR, Moore AT, et al. Retinal structure and function in achromatopsia: implications for gene therapy. Ophthalmology. 121: 234-45. PMID 24148654 DOI: 10.1016/J.Ophtha.2013.08.017 |
0.355 |
|
| 2013 |
Annear MJ, Mowat FM, Bartoe JT, Querubin J, Azam SA, Basche M, Curran PG, Smith AJ, Bainbridge JW, Ali RR, Petersen-Jones SM. Successful gene therapy in older Rpe65-deficient dogs following subretinal injection of an adeno-associated vector expressing RPE65. Human Gene Therapy. 24: 883-93. PMID 24028205 DOI: 10.1089/Hum.2013.146 |
0.305 |
|
| 2013 |
Gonzalez-Cordero A, West EL, Pearson RA, Duran Y, Carvalho LS, Chu CJ, Naeem A, Blackford SJ, Georgiadis A, Lakowski J, Hubank M, Smith AJ, Bainbridge JW, Sowden JC, Ali RR. Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina. Nature Biotechnology. 31: 741-7. PMID 23873086 DOI: 10.1038/nbt.2643 |
0.814 |
|
| 2013 |
Chu CJ, Herrmann P, Carvalho LS, Liyanage SE, Bainbridge JW, Ali RR, Dick AD, Luhmann UF. Assessment and in vivo scoring of murine experimental autoimmune uveoretinitis using optical coherence tomography. Plos One. 8: e63002. PMID 23690973 DOI: 10.1371/journal.pone.0063002 |
0.34 |
|
| 2013 |
Barber AC, Hippert C, Duran Y, West EL, Bainbridge JW, Warre-Cornish K, Luhmann UF, Lakowski J, Sowden JC, Ali RR, Pearson RA. Repair of the degenerate retina by photoreceptor transplantation. Proceedings of the National Academy of Sciences of the United States of America. 110: 354-9. PMID 23248312 DOI: 10.1073/Pnas.1212677110 |
0.813 |
|
| 2013 |
Luhmann UF, Carvalho LS, Robbie SJ, Cowing JA, Duran Y, Munro PM, Bainbridge JW, Ali RR. Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration. Experimental Eye Research. 107: 80-7. PMID 23232206 DOI: 10.1016/j.exer.2012.11.015 |
0.323 |
|
| 2012 |
Lange CA, Luhmann UF, Mowat FM, Georgiadis A, West EL, Abrahams S, Sayed H, Powner MB, Fruttiger M, Smith AJ, Sowden JC, Maxwell PH, Ali RR, Bainbridge JW. Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development. Development (Cambridge, England). 139: 2340-50. PMID 22627278 DOI: 10.1242/Dev.070813 |
0.669 |
|
| 2012 |
West EL, Gonzalez-Cordero A, Hippert C, Osakada F, Martinez-Barbera JP, Pearson RA, Sowden JC, Takahashi M, Ali RR. Defining the integration capacity of embryonic stem cell-derived photoreceptor precursors. Stem Cells (Dayton, Ohio). 30: 1424-35. PMID 22570183 DOI: 10.1002/Stem.1123 |
0.825 |
|
| 2012 |
Luhmann UF, Lange CA, Robbie S, Munro PM, Cowing JA, Armer HE, Luong V, Carvalho LS, MacLaren RE, Fitzke FW, Bainbridge JW, Ali RR. Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling. Plos One. 7: e35551. PMID 22545116 DOI: 10.1371/journal.pone.0035551 |
0.367 |
|
| 2012 |
Pearson RA, Barber AC, Rizzi M, Hippert C, Xue T, West EL, Duran Y, Smith AJ, Chuang JZ, Azam SA, Luhmann UF, Benucci A, Sung CH, Bainbridge JW, Carandini M, ... ... Ali RR, et al. Restoration of vision after transplantation of photoreceptors. Nature. 485: 99-103. PMID 22522934 DOI: 10.1038/Nature10997 |
0.799 |
|
| 2012 |
Mowat FM, Gonzalez F, Luhmann UF, Lange CA, Duran Y, Smith AJ, Maxwell PH, Ali RR, Bainbridge JW. Endogenous erythropoietin protects neuroretinal function in ischemic retinopathy. The American Journal of Pathology. 180: 1726-39. PMID 22342523 DOI: 10.1016/J.Ajpath.2011.12.033 |
0.398 |
|
| 2012 |
West EL, Pearson RA, Duran Y, Gonzalez-Cordero A, MacLaren RE, Smith AJ, Sowden JC, Ali RR. Manipulation of the recipient retinal environment by ectopic expression of neurotrophic growth factors can improve transplanted photoreceptor integration and survival. Cell Transplantation. 21: 871-87. PMID 22325046 DOI: 10.3727/096368911X623871 |
0.812 |
|
| 2012 |
Sundaram V, Moore AT, Ali RR, Bainbridge JW. Educational paper: Retinal dystrophies and gene therapy European Journal of Pediatrics. 171: 757-765. PMID 22080959 DOI: 10.1007/S00431-011-1615-2 |
0.444 |
|
| 2012 |
Ali RR, Bainbridge JW. Retinal cell transplantation: prospects for the future Expert Review of Ophthalmology. 7: 99-101. DOI: 10.1586/eop.12.9 |
0.547 |
|
| 2011 |
Gualdoni S, Baron M, Lakowski J, Decembrini S, Pearson RA, Ali RR, Sowden JC. Isolation and culture of adult ciliary epithelial cells, previously identified as retinal stem cells, and retinal progenitor cells. Current Protocols in Stem Cell Biology. Unit 1H.4. PMID 22135083 DOI: 10.1002/9780470151808.sc01h04s19 |
0.773 |
|
| 2011 |
Shu X, Luhmann UF, Aleman TS, Barker SE, Lennon A, Tulloch B, Chen M, Xu H, Jacobson SG, Ali R, Wright AF. Characterisation of a C1qtnf5 Ser163Arg knock-in mouse model of late-onset retinal macular degeneration. Plos One. 6: e27433. PMID 22110650 DOI: 10.1371/Journal.Pone.0027433 |
0.454 |
|
| 2011 |
Smith AJ, Bainbridge JW, Ali RR. Gene supplementation therapy for recessive forms of inherited retinal dystrophies. Gene Therapy. 19: 154-61. PMID 22033465 DOI: 10.1038/gt.2011.161 |
0.383 |
|
| 2011 |
Lakowski J, Han YT, Pearson RA, Gonzalez-Cordero A, West EL, Gualdoni S, Barber AC, Hubank M, Ali RR, Sowden JC. Effective transplantation of photoreceptor precursor cells selected via cell surface antigen expression. Stem Cells (Dayton, Ohio). 29: 1391-404. PMID 21774040 DOI: 10.1002/stem.694 |
0.777 |
|
| 2011 |
Boucherie C, Sowden JC, Ali RR. Induced pluripotent stem cell technology for generating photoreceptors. Regenerative Medicine. 6: 469-79. PMID 21749205 DOI: 10.2217/rme.11.37 |
0.689 |
|
| 2011 |
Mihelec M, Pearson RA, Robbie SJ, Buch PK, Azam SA, Bainbridge JW, Smith AJ, Ali RR. Long-term preservation of cones and improvement in visual function following gene therapy in a mouse model of leber congenital amaurosis caused by guanylate cyclase-1 deficiency. Human Gene Therapy. 22: 1179-90. PMID 21671801 DOI: 10.1089/hum.2011.069 |
0.59 |
|
| 2011 |
Carvalho LS, Xu J, Pearson RA, Smith AJ, Bainbridge JW, Morris LM, Fliesler SJ, Ding XQ, Ali RR. Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy. Human Molecular Genetics. 20: 3161-75. PMID 21576125 DOI: 10.1093/hmg/ddr218 |
0.558 |
|
| 2011 |
Ali RR, Sowden JC. Regenerative medicine: DIY eye. Nature. 472: 42-3. PMID 21475187 DOI: 10.1038/472042a |
0.568 |
|
| 2011 |
Buch PK, Mihelec M, Cottrill P, Wilkie SE, Pearson RA, Duran Y, West EL, Michaelides M, Ali RR, Hunt DM. Dominant cone-rod dystrophy: a mouse model generated by gene targeting of the GCAP1/Guca1a gene. Plos One. 6: e18089. PMID 21464903 DOI: 10.1371/journal.pone.0018089 |
0.598 |
|
| 2011 |
Decembrini S, Cananzi M, Gualdoni S, Battersby A, Allen N, Pearson RA, Ali RR, De Coppi P, Sowden JC. Comparative analysis of the retinal potential of embryonic stem cells and amniotic fluid-derived stem cells. Stem Cells and Development. 20: 851-63. PMID 20939691 DOI: 10.1089/scd.2010.0291 |
0.792 |
|
| 2011 |
Sowden JC, Ali RR. Stem cell therapy for blindness: new developments and implications for the future Expert Review of Ophthalmology. 6: 1-3. DOI: 10.1586/eop.10.86 |
0.618 |
|
| 2010 |
Georgiadis A, Tschernutter M, Bainbridge JW, Balaggan KS, Mowat F, West EL, Munro PM, Thrasher AJ, Matter K, Balda MS, Ali RR. The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice. Plos One. 5: e15730. PMID 21209887 DOI: 10.1371/journal.pone.0015730 |
0.398 |
|
| 2010 |
West EL, Pearson RA, Barker SE, Luhmann UF, Maclaren RE, Barber AC, Duran Y, Smith AJ, Sowden JC, Ali RR. Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation. Stem Cells (Dayton, Ohio). 28: 1997-2007. PMID 20857496 DOI: 10.1002/stem.520 |
0.826 |
|
| 2010 |
Aartsen WM, van Cleef KW, Pellissier LP, Hoek RM, Vos RM, Blits B, Ehlert EM, Balaggan KS, Ali RR, Verhaagen J, Wijnholds J. GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors. Plos One. 5: e12387. PMID 20808778 DOI: 10.1371/Journal.Pone.0012387 |
0.483 |
|
| 2010 |
Gualdoni S, Baron M, Lakowski J, Decembrini S, Smith AJ, Pearson RA, Ali RR, Sowden JC. Adult ciliary epithelial cells, previously identified as retinal stem cells with potential for retinal repair, fail to differentiate into new rod photoreceptors. Stem Cells (Dayton, Ohio). 28: 1048-59. PMID 20506130 DOI: 10.1002/stem.423 |
0.807 |
|
| 2010 |
Pearson RA, Barber AC, West EL, MacLaren RE, Duran Y, Bainbridge JW, Sowden JC, Ali RR. Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina. Cell Transplantation. 19: 487-503. PMID 20089206 DOI: 10.3727/096368909X486057 |
0.8 |
|
| 2010 |
Stockman A, Ripamonti C, Henning GB, Robbie SJ, Moore AT, Bainbridge JW, Ali RR. Restoration of rod function following gene therapy in patients with mutations in the gene encoding the RPE65 protein required for recycling all-trans-retinal to 11-cis-retinal Journal of Vision. 10: 59-59. DOI: 10.1167/10.15.59 |
0.343 |
|
| 2009 |
Sun X, Pawlyk B, Xu X, Liu X, Bulgakov OV, Adamian M, Sandberg MA, Khani SC, Tan MH, Smith AJ, Ali RR, Li T. Gene therapy with a promoter targeting both rods and cones rescues retinal degeneration caused by AIPL1 mutations. Gene Therapy. 17: 117-31. PMID 19710705 DOI: 10.1038/gt.2009.104 |
0.396 |
|
| 2009 |
West EL, Pearson RA, MacLaren RE, Sowden JC, Ali RR. Cell transplantation strategies for retinal repair. Progress in Brain Research. 175: 3-21. PMID 19660645 DOI: 10.1016/S0079-6123(09)17501-5 |
0.823 |
|
| 2009 |
Smith AJ, Bainbridge JW, Ali RR. Prospects for retinal gene replacement therapy. Trends in Genetics : Tig. 25: 156-65. PMID 19303164 DOI: 10.1016/j.tig.2009.02.003 |
0.309 |
|
| 2009 |
Tan MH, Smith AJ, Pawlyk B, Xu X, Liu X, Bainbridge JB, Basche M, McIntosh J, Tran HV, Nathwani A, Li T, Ali RR. Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectors. Human Molecular Genetics. 18: 2099-114. PMID 19299492 DOI: 10.1093/hmg/ddp133 |
0.393 |
|
| 2008 |
Mowat FM, Petersen-Jones SM, Williamson H, Williams DL, Luthert PJ, Ali RR, Bainbridge JW. Topographical characterization of cone photoreceptors and the area centralis of the canine retina. Molecular Vision. 14: 2518-27. PMID 19112529 |
0.395 |
|
| 2008 |
Bainbridge JW, Smith AJ, Barker SS, Robbie S, Henderson R, Balaggan K, Viswanathan A, Holder GE, Stockman A, Tyler N, Petersen-Jones S, Bhattacharya SS, Thrasher AJ, Fitzke FW, Carter BJ, ... ... Ali RR, et al. Effect of gene therapy on visual function in Leber's congenital amaurosis. The New England Journal of Medicine. 358: 2231-9. PMID 18441371 DOI: 10.1056/Nejmoa0802268 |
0.345 |
|
| 2008 |
Buch PK, Bainbridge JW, Ali RR. AAV-mediated gene therapy for retinal disorders: from mouse to man. Gene Therapy. 15: 849-57. PMID 18418417 DOI: 10.1038/gt.2008.66 |
0.394 |
|
| 2008 |
Natkunarajah M, Trittibach P, McIntosh J, Duran Y, Barker SE, Smith AJ, Nathwani AC, Ali RR. Assessment of ocular transduction using single-stranded and self-complementary recombinant adeno-associated virus serotype 2/8. Gene Therapy. 15: 463-7. PMID 18004402 DOI: 10.1038/sj.gt.3303074 |
0.44 |
|
| 2008 |
Bainbridge J, Ali R. Gene therapy for inherited childhood blindness shows promise Expert Review of Ophthalmology. 3: 357-359. DOI: 10.1586/17469899.3.4.357 |
0.346 |
|
| 2007 |
Buch PK, MacLaren RE, Ali RR. Neuroprotective gene therapy for the treatment of inherited retinal degeneration. Current Gene Therapy. 7: 434-45. PMID 18045103 DOI: 10.2174/156652307782793531 |
0.332 |
|
| 2007 |
Khani SC, Pawlyk BS, Bulgakov OV, Kasperek E, Young JE, Adamian M, Sun X, Smith AJ, Ali RR, Li T. AAV-mediated expression targeting of rod and cone photoreceptors with a human rhodopsin kinase promoter. Investigative Ophthalmology & Visual Science. 48: 3954-61. PMID 17724172 DOI: 10.1167/iovs.07-0257 |
0.312 |
|
| 2007 |
MacNeil A, Pearson RA, MacLaren RE, Smith AJ, Sowden JC, Ali RR. Comparative analysis of progenitor cells isolated from the iris, pars plana, and ciliary body of the adult porcine eye. Stem Cells (Dayton, Ohio). 25: 2430-8. PMID 17600111 DOI: 10.1634/stemcells.2007-0035 |
0.765 |
|
| 2007 |
MacLaren RE, Uppal GS, Balaggan KS, Tufail A, Munro PM, Milliken AB, Ali RR, Rubin GS, Aylward GW, da Cruz L. Autologous transplantation of the retinal pigment epithelium and choroid in the treatment of neovascular age-related macular degeneration. Ophthalmology. 114: 561-70. PMID 17324698 DOI: 10.1016/j.ophtha.2006.06.049 |
0.403 |
|
| 2006 |
Rolling F, Le Meur G, Stieger K, Smith AJ, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Péréon Y, Cherel Y, Ali RR, Hamel C, Moullier P, Rolling F. Gene therapeutic prospects in early onset of severe retinal dystrophy: restoration of vision in RPE65 Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Bulletin Et Memoires De L'Academie Royale De Medecine De Belgique. 161: 497-508; discussion . PMID 17503728 |
0.406 |
|
| 2006 |
Le Meur G, Stieger K, Smith AJ, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Péréon Y, Cherel Y, Ali RR, Hamel C, Moullier P, Rolling F. Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Gene Therapy. 14: 292-303. PMID 17024105 DOI: 10.1038/Sj.Gt.3302861 |
0.384 |
|
| 2006 |
Buch PK, MacLaren RE, Durán Y, Balaggan KS, MacNeil A, Schlichtenbrede FC, Smith AJ, Ali RR. In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 700-9. PMID 16872907 DOI: 10.1016/j.ymthe.2006.05.019 |
0.456 |
|
| 2006 |
Bainbridge JW, Tan MH, Ali RR. Gene therapy progress and prospects: the eye. Gene Therapy. 13: 1191-7. PMID 16838031 DOI: 10.1038/sj.gt.3302812 |
0.329 |
|
| 2006 |
MacLaren RE, Buch PK, Smith AJ, Balaggan KS, MacNeil A, Taylor JS, Osborne NN, Ali RR. CNTF gene transfer protects ganglion cells in rat retinae undergoing focal injury and branch vessel occlusion. Experimental Eye Research. 83: 1118-27. PMID 16831422 DOI: 10.1016/j.exer.2006.05.019 |
0.39 |
|
| 2006 |
Dhomen NS, Balaggan KS, Pearson RA, Bainbridge JW, Levine EM, Ali RR, Sowden JC. Absence of chx10 causes neural progenitors to persist in the adult retina. Investigative Ophthalmology & Visual Science. 47: 386-96. PMID 16384989 DOI: 10.1167/Iovs.05-0428 |
0.733 |
|
| 2006 |
Surace EM, Balaggan KS, Tessitore A, Mussolino C, Cotugno G, Bonetti C, Vitale A, Ali RR, Auricchio A. Inhibition of ocular neovascularization by hedgehog blockade. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 573-9. PMID 16343995 DOI: 10.1016/J.Ymthe.2005.10.010 |
0.369 |
|
| 2005 |
Pawlyk BS, Smith AJ, Buch PK, Adamian M, Hong DH, Sandberg MA, Ali RR, Li T. Gene replacement therapy rescues photoreceptor degeneration in a murine model of Leber congenital amaurosis lacking RPGRIP. Investigative Ophthalmology & Visual Science. 46: 3039-45. PMID 16123399 DOI: 10.1167/iovs.05-0371 |
0.398 |
|
| 2005 |
Sarra GM, Sarra FG, Schlichtenbrede FC, Trittibach P, Estermann S, Tsiroukis E, Ali RR, Luthert PJ, Reichel MB. Effect of steroidal and non-steroidal drugs on the microglia activation pattern and the course of degeneration in the retinal degeneration slow mouse. Ophthalmic Research. 37: 72-82. PMID 15746562 DOI: 10.1159/000084248 |
0.332 |
|
| 2005 |
Tschernutter M, Schlichtenbrede FC, Howe S, Balaggan KS, Munro PM, Bainbridge JW, Thrasher AJ, Smith AJ, Ali RR. Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy. Gene Therapy. 12: 694-701. PMID 15660111 DOI: 10.1038/sj.gt.3302460 |
0.445 |
|
| 2004 |
Schlichtenbrede FC, Smith AJ, Bainbridge JW, Thrasher AJ, Salt TE, Ali RR. Improvement of neuronal visual responses in the superior colliculus in Prph2(Rd2/Rd2) mice following gene therapy. Molecular and Cellular Neurosciences. 25: 103-10. PMID 14962744 DOI: 10.1016/j.mcn.2003.09.020 |
0.334 |
|
| 2004 |
Ali RR. Prospects for gene therapy. Novartis Foundation Symposium. 255: 165-72; discussion 1. PMID 14750603 |
0.452 |
|
| 2003 |
Schlichtenbrede FC, da Cruz L, Stephens C, Smith AJ, Georgiadis A, Thrasher AJ, Bainbridge JWB, Seeliger MW, Ali RR. Long-term evaluation of retinal function in Prph2Rd2/Rd2 mice following AAV-mediated gene replacement therapy Journal of Gene Medicine. 5: 757-764. PMID 12950066 DOI: 10.1002/jgm.401 |
0.302 |
|
| 2003 |
Ali RR, Sowden JC. Therapy may yet stem from cells in the retina. The British Journal of Ophthalmology. 87: 1058-9. PMID 12928264 DOI: 10.1136/bjo.87.9.1058 |
0.67 |
|
| 2003 |
Smith AJ, Schlichtenbrede FC, Tschernutter M, Bainbridge JW, Thrasher AJ, Ali RR. AAV-mediated gene transfer slows photoreceptor loss in the RCS rat model of retinitis pigmentosa Molecular Therapy. 8: 188-195. PMID 12907141 DOI: 10.1016/S1525-0016(03)00144-8 |
0.39 |
|
| 2003 |
Bainbridge JW, Mistry A, Schlichtenbrede FC, Smith A, Broderick C, De Alwis M, Georgiadis A, Taylor PM, Squires M, Sethi C, Charteris D, Thrasher AJ, Sargan D, Ali RR. Stable rAAV-mediated transduction of rod and cone photoreceptors in the canine retina. Gene Therapy. 10: 1336-44. PMID 12883530 DOI: 10.1038/sj.gt.3301990 |
0.452 |
|
| 2003 |
Bainbridge JW, Mistry A, Binley K, De Alwis M, Thrasher AJ, Naylor S, Ali RR. Hypoxia-regulated transgene expression in experimental retinal and choroidal neovascularization. Gene Therapy. 10: 1049-54. PMID 12776163 DOI: 10.1038/sj.gt.3301945 |
0.304 |
|
| 2003 |
Hughes EH, Schlichtenbrede FC, Murphy CC, Sarra GM, Luthert PJ, Ali RR, Dick AD. Generation of activated sialoadhesin-positive microglia during retinal degeneration Investigative Ophthalmology and Visual Science. 44: 2229-2234. PMID 12714665 DOI: 10.1167/iovs.02-0824 |
0.428 |
|
| 2002 |
Schlichtenbrede FC, Sarra GM, Ali RR, Wiedemann P, Reichel MB. [Progress in somatic gene therapy of retinal degeneration in the animal model]. Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft. 99: 259-65. PMID 12058500 DOI: 10.1007/s00347-002-0633-x |
0.391 |
|
| 2002 |
Sarra GM, Stephens C, Schlichtenbrede FC, Bainbridge JWB, Thrasher AJ, Luthert PJ, Ali RR. Kinetics of transgene expression in mouse retina following sub-retinal injection of recombinant adeno-associated virus Vision Research. 42: 541-549. PMID 11853771 DOI: 10.1016/S0042-6989(01)00230-9 |
0.373 |
|
| 2002 |
Bainbridge J, Mistry A, De Alwis M, Thrasher A, Ali R. Control of Retinal Angiogenesis by Local Gene Tranfer of a VEGF Inhibitor Clinical Science. 103: 1P-1P. DOI: 10.1042/Cs103001P |
0.369 |
|
| 2001 |
Sarra GM, Stephens C, de Alwis M, Bainbridge JW, Smith AJ, Thrasher AJ, Ali RR. Gene replacement therapy in the retinal degeneration slow (rds) mouse: the effect on retinal degeneration following partial transduction of the retina. Human Molecular Genetics. 10: 2353-61. PMID 11689482 DOI: 10.1093/HMG/10.21.2353 |
0.445 |
|
| 2001 |
Bessant DA, Ali RR, Bhattacharya SS. Molecular genetics and prospects for therapy of the inherited retinal dystrophies. Current Opinion in Genetics & Development. 11: 307-16. PMID 11377968 DOI: 10.1016/S0959-437X(00)00195-7 |
0.408 |
|
| 2001 |
Reichel MB, Bainbridge J, Baker D, Thrasher AJ, Bhattaharya SS, Ali RR. An immune response after intraocular administration of an adenoviral vector containing a β galactosidase reporter gene slows retinal degeneration in the rd mouse British Journal of Ophthalmology. 85: 341-344. PMID 11222343 DOI: 10.1136/Bjo.85.3.341 |
0.314 |
|
| 2000 |
Ali RR, Sarra GM, Stephens C, Alwis MD, Bainbridge JW, Munro PM, Fauser S, Reichel MB, Kinnon C, Hunt DM, Bhattacharya SS, Thrasher AJ. Restoration of photoreceptor ultrastructure and function in retinal degeneration slow mice by gene therapy. Nature Genetics. 25: 306-10. PMID 10888879 DOI: 10.1038/77068 |
0.453 |
|
| 1998 |
Reichel MB, Ali RR, Thrasher AJ, Hunt DM, Bhattacharya SS, Baker D. Immune responses limit adenovirally mediated gene expression in the adult mouse eye Gene Therapy. 5: 1038-1046. PMID 10326026 DOI: 10.1038/Sj.Gt.3300691 |
0.356 |
|
| 1998 |
Ali RR, Reichel MB, Byrnes AP, Stephens CJ, Thrasher AJ, Baker D, Hunt DM, Bhattacharya SS. Co-injection of adenovirus expressing CTLA4-Ig prolongs adenovirally mediated lacZ reporter gene expression in the mouse retina Gene Therapy. 5: 1561-1565. PMID 9930310 DOI: 10.1038/Sj.Gt.3300761 |
0.399 |
|
| 1998 |
Ali RR, Reichel MB, Kanuga N, Munro PM, Alexander RA, Clarke AR, Luthert PJ, Bhattacharya SS, Hunt DM. Absence of p53 delays apoptotic photoreceptor cell death in the rds mouse. Current Eye Research. 17: 917-23. PMID 9746439 DOI: 10.1076/CEYR.17.9.917.5137 |
0.358 |
|
| 1998 |
Ali RR, Reichel MB, De Alwis M, Kanuga N, Kinnon C, Levinsky RJ, Hunt DM, Bhattacharya SS, Thrasher AJ. Adeno-associated virus gene transfer to mouse retina. Human Gene Therapy. 9: 81-6. PMID 9458245 DOI: 10.1089/Hum.1998.9.1-81 |
0.401 |
|
| 1998 |
Ali RR, Reichel MB, Hunt DM, Bhattacharya SS. Gene therapy for inherited retinal degeneration. The British Journal of Ophthalmology. 81: 795-801. PMID 9422936 DOI: 10.1136/bjo.81.9.795 |
0.336 |
|
| 1997 |
Reichel MB, Ali RR, Hunt DM, Bhattacharya SS. Gene therapy for retinal degeneration. Ophthalmic Research. 29: 261-8. PMID 9323717 DOI: 10.1159/000268024 |
0.304 |
|
| 1996 |
Ali RR, Reichel MB, Thrasher AJ, Levinsky RJ, Kinnon C, Kanuga N, Hunt DM, Bhattacharya SS. Gene transfer into the mouse retina mediated by an adeno-associated viral vector Human Molecular Genetics. 5: 591-594. PMID 8733124 DOI: 10.1093/Hmg/5.5.591 |
0.445 |
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