| Year |
Citation |
Score |
| 2020 |
Carreca AP, Pravatà VM, Markham M, Bonelli S, Murphy G, Nagase H, Troeberg L, Scilabra SD. TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1. Scientific Reports. 10: 12067. PMID 32694578 DOI: 10.1038/S41598-020-69008-9 |
0.609 |
|
| 2019 |
Schubert K, Collins LE, Green P, Nagase H, Troeberg L. LRP1 Controls TNF Release via the TIMP-3/ADAM17 Axis in Endotoxin-Activated Macrophages. Journal of Immunology (Baltimore, Md. : 1950). PMID 30659107 DOI: 10.4049/Jimmunol.1800834 |
0.372 |
|
| 2018 |
Mekkat A, Poppleton E, An B, Visse R, Nagase H, Kaplan DL, Brodsky B, Lin YS. Effects of flexibility of the α2 chain of type I collagen on collagenase cleavage. Journal of Structural Biology. PMID 29763735 DOI: 10.1016/J.Jsb.2018.05.002 |
0.479 |
|
| 2018 |
Santamaria S, Nagase H. Measurement of Protease Activities Using Fluorogenic Substrates. Methods in Molecular Biology (Clifton, N.J.). 1731: 107-122. PMID 29318548 DOI: 10.1007/978-1-4939-7595-2_11 |
0.384 |
|
| 2018 |
Lund J, Elimar Bitsch AM, Grønbech Rasch M, Enoksson M, Troeberg L, Nagase H, Loftager M, Overgaard MT, Petersen HH. Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma. Mabs. 10: 118-128. PMID 29185848 DOI: 10.1080/19420862.2017.1395541 |
0.339 |
|
| 2018 |
Yamamoto K, Scavenius C, Santamaria S, Botkjaer KA, Dudhia J, Troeberg L, Itoh Y, Murphy G, Enghild JJ, Nagase H. Inhibition of LRP1 shedding reverses cartilage degradation in osteoarthritis Osteoarthritis and Cartilage. 26. DOI: 10.1016/J.Joca.2018.02.060 |
0.42 |
|
| 2018 |
Duro-Castano A, Lim NH, Tranchant I, Amoura M, Beau F, Wieland H, Kingler O, Herrmann M, Nazaré M, Plettenburg O, Dive V, Vicent MJ, Nagase H. In Vivo Imaging of MMP-13 Activity Using a Specific Polymer-FRET Peptide Conjugate Detects Early Osteoarthritis and Inhibitor Efficacy Advanced Functional Materials. 28: 1802738. DOI: 10.1002/Adfm.201802738 |
0.503 |
|
| 2017 |
Chanalaris A, Doherty C, Marsden BD, Bambridge G, Wren SP, Nagase H, Troeberg L. Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3 (TIMP-3). Molecular Pharmacology. PMID 28798097 DOI: 10.1124/mol.117.109397 |
0.448 |
|
| 2017 |
Santamaria S, Fedorov O, McCafferty J, Murphy G, Dudhia J, Nagase H, Yamamoto K. Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1. Mabs. 0. PMID 28306378 DOI: 10.1080/19420862.2017.1304341 |
0.328 |
|
| 2017 |
Yamamoto K, Santamaria S, Botkjaer KA, Dudhia J, Troeberg L, Itoh Y, Murphy G, Nagase H. Inhibition of shedding of low-density lipoprotein receptor-related protein 1 reverses cartilage matrix degradation in osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28235248 DOI: 10.1002/Art.40080 |
0.462 |
|
| 2017 |
Scilabra SD, Yamamoto K, Pigoni M, Sakamoto K, Müller SA, Papadopoulou A, Lichtenthaler SF, Troeberg L, Nagase H, Kadomatsu K. Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a "TRAP" to increase levels of TIMP-3 in the tissue. Matrix Biology : Journal of the International Society For Matrix Biology. 59: 69-79. PMID 27476612 DOI: 10.1016/J.Matbio.2016.07.004 |
0.493 |
|
| 2016 |
Poulet B, Liu K, Plumb D, Vo P, Shah M, Staines K, Sampson A, Nakamura H, Nagase H, Carriero A, Shefelbine S, Pitsillides AA, Bou-Gharios G. Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity. Plos One. 11: e0167971. PMID 28002442 DOI: 10.1371/Journal.Pone.0167971 |
0.332 |
|
| 2016 |
Solomonov I, Zehorai E, Talmi-Frank D, Wolf SG, Shainskaya A, Zhuravlev A, Kartvelishvily E, Visse R, Levin Y, Kampf N, Jaitin DA, David E, Amit I, Nagase H, Sagi I. Distinct biological events generated by ECM proteolysis by two homologous collagenases. Proceedings of the National Academy of Sciences of the United States of America. PMID 27630193 DOI: 10.1073/Pnas.1519676113 |
0.511 |
|
| 2016 |
Doherty CM, Visse R, Dinakarpandian D, Strickland DK, Nagase H, Troeberg L. Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity. The Journal of Biological Chemistry. PMID 27582494 DOI: 10.1074/Jbc.M116.733261 |
0.545 |
|
| 2016 |
Nagase H. A personal journey with matrix metalloproteinases. Biological Chemistry. 397: 805-13. PMID 27341559 DOI: 10.1515/Hsz-2016-0169 |
0.578 |
|
| 2016 |
Yamamoto K, Okano H, Miyagawa W, Visse R, Shitomi Y, Santamaria S, Dudhia J, Troeberg L, Strickland DK, Hirohata S, Nagase H. MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 27084377 DOI: 10.1016/J.Matbio.2016.03.007 |
0.622 |
|
| 2015 |
Ismail HM, Miotla-Zarebska J, Troeberg L, Tang X, Stott B, Yamamoto K, Nagase H, Fosang AJ, Vincent TL, Saklatvala J. JNK2 controls aggrecan degradation in murine articular cartilage and the development of experimental osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26663140 DOI: 10.1002/Art.39547 |
0.384 |
|
| 2015 |
Santamaria S, Yamamoto K, Botkjaer K, Tape C, Dyson MR, McCafferty J, Murphy G, Nagase H. Anti-body-based exosite inhibitors of ADAMTS-5 (Aggrecanase-2). The Biochemical Journal. PMID 26303525 DOI: 10.1042/Bj20150758 |
0.357 |
|
| 2015 |
Lund J, Troeberg L, Kjeldal H, Olsen OH, Nagase H, Sørensen ES, Stennicke HR, Petersen HH, Overgaard MT. Evidence for restricted reactivity of ADAMDEC1 with protein substrates and endogenous inhibitors. The Journal of Biological Chemistry. 290: 6620-9. PMID 25564618 DOI: 10.1074/Jbc.M114.601724 |
0.453 |
|
| 2015 |
Cui H, Seubert B, Stahl E, Dietz H, Reuning U, Moreno-Leon L, Ilie M, Hofman P, Nagase H, Mari B, Krüger A. Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of miR-210 in lung adenocarcinoma cells and their exosomes. Oncogene. 34: 3640-50. PMID 25263437 DOI: 10.1038/Onc.2014.300 |
0.348 |
|
| 2015 |
Seubert B, Grünwald B, Kobuch J, Cui H, Schelter F, Schaten S, Siveke JT, Lim NH, Nagase H, Simonavicius N, Heikenwalder M, Reinheckel T, Sleeman JP, Janssen KP, Knolle PA, et al. Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice. Hepatology (Baltimore, Md.). 61: 238-48. PMID 25131778 DOI: 10.1002/Hep.27378 |
0.422 |
|
| 2015 |
Kelwick R, Wagstaff L, Decock J, Roghi C, Cooley LS, Robinson SD, Arnold H, Gavrilović J, Jaworski DM, Yamamoto K, Nagase H, Seubert B, Krüger A, Edwards DR. Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15. International Journal of Cancer. Journal International Du Cancer. 136: E14-26. PMID 25099234 DOI: 10.1002/Ijc.29129 |
0.464 |
|
| 2015 |
Lim NH, Hu H, Nazare M, Plettenburg O, Nagase H, Schultz C. Development of imaging agents for the visualisation of cartilage in vivo Osteoarthritis and Cartilage. 23. DOI: 10.1016/J.Joca.2015.02.399 |
0.328 |
|
| 2014 |
Troeberg L, Lazenbatt C, Anower-E-Khuda MF, Freeman C, Federov O, Habuchi H, Habuchi O, Kimata K, Nagase H. Sulfated glycosaminoglycans control the extracellular trafficking and the activity of the metalloprotease inhibitor TIMP-3. Chemistry & Biology. 21: 1300-9. PMID 25176127 DOI: 10.1016/J.Chembiol.2014.07.014 |
0.543 |
|
| 2014 |
Lim NH, Meinjohanns E, Meldal MP, Bou-Gharios G, Nagase H. In vivo imaging of MMP-13 activity in the murine destabilised medial meniscus surgical model of osteoarthritis. Osteoarthritis and Cartilage. 22: 862-868. PMID 24747174 DOI: 10.1016/J.Joca.2014.04.006 |
0.468 |
|
| 2014 |
Lim NH, Meinjohanns E, Bou-Gharios G, Gompels LL, Nuti E, Rossello A, Devel L, Dive V, Meldal M, Nagase H. In vivo imaging of matrix metalloproteinase 12 and matrix metalloproteinase 13 activities in the mouse model of collagen-induced arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 66: 589-98. PMID 24574219 DOI: 10.1002/Art.38295 |
0.587 |
|
| 2014 |
Yamamoto K, Owen K, Parker AE, Scilabra SD, Dudhia J, Strickland DK, Troeberg L, Nagase H. Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding. The Journal of Biological Chemistry. 289: 6462-74. PMID 24474687 DOI: 10.1074/Jbc.M113.545376 |
0.344 |
|
| 2013 |
Yu M, Lim NH, Ellis S, Nagase H, Triccas JA, Rutledge PJ, Todd MH. Incorporation of Bulky and Cationic Cyclam-Triazole Moieties into Marimastat Can Generate Potent MMP Inhibitory Activity without Inducing Cytotoxicity. Chemistryopen. 2: 99-105. PMID 24551546 DOI: 10.1002/Open.201300014 |
0.495 |
|
| 2013 |
Maingot L, Elbakali J, Dumont J, Bosc D, Cousaert N, Urban A, Deglane G, Villoutreix B, Nagase H, Sperandio O, Leroux F, Deprez B, Deprez-Poulain R. Aggrecanase-2 inhibitors based on the acylthiosemicarbazide zinc-binding group. European Journal of Medicinal Chemistry. 69: 244-61. PMID 24044937 DOI: 10.1016/J.Ejmech.2013.08.027 |
0.367 |
|
| 2013 |
Stura EA, Visse R, Cuniasse P, Dive V, Nagase H. Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 4395-405. PMID 23913860 DOI: 10.1096/Fj.13-233601 |
0.491 |
|
| 2013 |
Nuti E, Santamaria S, Casalini F, Yamamoto K, Marinelli L, La Pietra V, Novellino E, Orlandini E, Nencetti S, Marini AM, Salerno S, Taliani S, Da Settimo F, Nagase H, Rossello A. Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: synthesis and biological evaluation. European Journal of Medicinal Chemistry. 62: 379-94. PMID 23376997 DOI: 10.1016/J.Ejmech.2012.12.058 |
0.556 |
|
| 2013 |
Scilabra SD, Troeberg L, Yamamoto K, Emonard H, Thøgersen I, Enghild JJ, Strickland DK, Nagase H. Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1. The Journal of Biological Chemistry. 288: 332-42. PMID 23166318 DOI: 10.1074/Jbc.M112.393322 |
0.579 |
|
| 2013 |
Yamamoto K, Troeberg L, Scilabra SD, Pelosi M, Murphy CL, Strickland DK, Nagase H. LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 511-21. PMID 23064555 DOI: 10.1096/Fj.12-216671 |
0.472 |
|
| 2013 |
Nagase H. Matrix Metalloproteinase 3/Stromelysin 1 Handbook of Proteolytic Enzymes. 1: 763-774. DOI: 10.1016/B978-0-12-382219-2.00158-7 |
0.478 |
|
| 2012 |
Madsen JL, Andersen TL, Santamaria S, Nagase H, Enghild JJ, Skrydstrup T. Synthesis and evaluation of silanediols as highly selective uncompetitive inhibitors of human neutrophil elastase. Journal of Medicinal Chemistry. 55: 7900-8. PMID 22882079 DOI: 10.1021/Jm301000K |
0.354 |
|
| 2012 |
Manka SW, Carafoli F, Visse R, Bihan D, Raynal N, Farndale RW, Murphy G, Enghild JJ, Hohenester E, Nagase H. Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1. Proceedings of the National Academy of Sciences of the United States of America. 109: 12461-6. PMID 22761315 DOI: 10.1073/Pnas.1204991109 |
0.592 |
|
| 2012 |
Yu Z, Visse R, Inouye M, Nagase H, Brodsky B. Defining requirements for collagenase cleavage in collagen type III using a bacterial collagen system. The Journal of Biological Chemistry. 287: 22988-97. PMID 22573319 DOI: 10.1074/Jbc.M112.348979 |
0.589 |
|
| 2012 |
Lo Cicero A, Majkowska I, Nagase H, Di Liegro I, Troeberg L. Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity. Matrix Biology : Journal of the International Society For Matrix Biology. 31: 229-33. PMID 22406378 DOI: 10.1016/J.Matbio.2012.02.005 |
0.545 |
|
| 2012 |
Troeberg L, Mulloy B, Ghosh P, Lee MH, Murphy G, Nagase H. Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex. The Biochemical Journal. 443: 307-15. PMID 22299597 DOI: 10.1042/Bj20112159 |
0.436 |
|
| 2012 |
La Pietra V, Marinelli L, Cosconati S, Di Leva FS, Nuti E, Santamaria S, Pugliesi I, Morelli M, Casalini F, Rossello A, La Motta C, Taliani S, Visse R, Nagase H, da Settimo F, et al. Identification of novel molecular scaffolds for the design of MMP-13 inhibitors: a first round of lead optimization. European Journal of Medicinal Chemistry. 47: 143-52. PMID 22088955 DOI: 10.1016/J.Ejmech.2011.10.035 |
0.551 |
|
| 2012 |
Troeberg L, Nagase H. Proteases involved in cartilage matrix degradation in osteoarthritis Biochimica Et Biophysica Acta - Proteins and Proteomics. 1824: 133-145. PMID 21777704 DOI: 10.1016/J.Bbapap.2011.06.020 |
0.53 |
|
| 2011 |
Itoh Y, Palmisano R, Anilkumar N, Nagase H, Miyawaki A, Seiki M. Dimerization of MT1-MMP during cellular invasion detected by fluorescence resonance energy transfer. The Biochemical Journal. 440: 319-26. PMID 21846327 DOI: 10.1042/Bj20110424 |
0.56 |
|
| 2011 |
Selvais C, D'Auria L, Tyteca D, Perrot G, Lemoine P, Troeberg L, Dedieu S, Noël A, Nagase H, Henriet P, Courtoy PJ, Marbaix E, Emonard H. Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2770-81. PMID 21518850 DOI: 10.1096/Fj.10-169508 |
0.492 |
|
| 2011 |
Durigova M, Troeberg L, Nagase H, Roughley PJ, Mort JS. Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage. European Cells & Materials. 21: 31-45. PMID 21225593 DOI: 10.22203/Ecm.V021A03 |
0.392 |
|
| 2011 |
Nagase H, Karamanos N. Metalloproteinases in health and disease: Challenges and the future prospects Febs Journal. 278: 1. PMID 21204304 DOI: 10.1111/J.1742-4658.2010.07917.X |
0.623 |
|
| 2011 |
Tochowicz A, Goettig P, Evans R, Visse R, Shitomi Y, Palmisano R, Ito N, Richter K, Maskos K, Franke D, Svergun D, Nagase H, Bode W, Itoh Y. The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions. The Journal of Biological Chemistry. 286: 7587-600. PMID 21193411 DOI: 10.1074/Jbc.M110.178434 |
0.542 |
|
| 2011 |
Caglič D, Globisch A, Kindermann M, Lim NH, Jeske V, Juretschke HP, Bartnik E, Weithmann KU, Nagase H, Turk B, Wendt KU. Functional in vivo imaging of cysteine cathepsin activity in murine model of inflammation. Bioorganic & Medicinal Chemistry. 19: 1055-61. PMID 21130662 DOI: 10.1016/J.Bmc.2010.10.028 |
0.323 |
|
| 2011 |
Murphy G, Nagase H. Localizing matrix metalloproteinase activities in the pericellular environment Febs Journal. 278: 2-15. PMID 21087456 DOI: 10.1111/J.1742-4658.2010.07918.X |
0.596 |
|
| 2011 |
Durigova M, Nagase H, Mort JS, Roughley PJ. MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein. Matrix Biology : Journal of the International Society For Matrix Biology. 30: 145-53. PMID 21055468 DOI: 10.1016/J.Matbio.2010.10.007 |
0.617 |
|
| 2011 |
Gardiner MD, Chanalaris A, Nagase H. 347 Gene Expression Profiling Of Cartilage Degradation In A Mouse Model Of Osteoarthritis Identifies Significant Alteration In Key Molecular Processes Osteoarthritis and Cartilage. 19. DOI: 10.1016/S1063-4584(11)60374-9 |
0.306 |
|
| 2010 |
Maingot L, Leroux F, Landry V, Dumont J, Nagase H, Villoutreix B, Sperandio O, Deprez-Poulain R, Deprez B. New non-hydroxamic ADAMTS-5 inhibitors based on the 1,2,4-triazole-3-thiol scaffold. Bioorganic & Medicinal Chemistry Letters. 20: 6213-6. PMID 20846863 DOI: 10.1016/J.Bmcl.2010.08.108 |
0.322 |
|
| 2010 |
Lim NH, Kashiwagi M, Visse R, Jones J, Enghild JJ, Brew K, Nagase H. Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications. The Biochemical Journal. 431: 113-22. PMID 20645923 DOI: 10.1042/Bj20100725 |
0.68 |
|
| 2010 |
Kveiborg M, Jacobsen J, Lee MH, Nagase H, Wewer UM, Murphy G. Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2). The Biochemical Journal. 430: 79-86. PMID 20533908 DOI: 10.1042/Bj20100649 |
0.521 |
|
| 2010 |
Han S, Makareeva E, Kuznetsova NV, DeRidder AM, Sutter MB, Losert W, Phillips CL, Visse R, Nagase H, Leikin S. Molecular mechanism of type I collagen homotrimer resistance to mammalian collagenases. The Journal of Biological Chemistry. 285: 22276-81. PMID 20463013 DOI: 10.1074/Jbc.M110.102079 |
0.45 |
|
| 2010 |
Makareeva E, Han S, Vera JC, Sackett DL, Holmbeck K, Phillips CL, Visse R, Nagase H, Leikin S. Carcinomas contain a matrix metalloproteinase-resistant isoform of type I collagen exerting selective support to invasion. Cancer Research. 70: 4366-74. PMID 20460529 DOI: 10.1158/0008-5472.Can-09-4057 |
0.483 |
|
| 2010 |
Bekhouche M, Kronenberg D, Vadon-Le Goff S, Bijakowski C, Lim NH, Font B, Kessler E, Colige A, Nagase H, Murphy G, Hulmes DJ, Moali C. Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity. The Journal of Biological Chemistry. 285: 15950-9. PMID 20207734 DOI: 10.1074/Jbc.M109.086447 |
0.502 |
|
| 2010 |
Pozgan U, Caglic D, Rozman B, Nagase H, Turk V, Turk B. Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis. Biological Chemistry. 391: 571-9. PMID 20180636 DOI: 10.1515/Bc.2010.035 |
0.398 |
|
| 2010 |
Shimokawa K, Nagase H. Purification of MMPs and TIMPs. Methods in Molecular Biology (Clifton, N.J.). 622: 123-55. PMID 20135280 DOI: 10.1007/978-1-60327-299-5_8 |
0.608 |
|
| 2010 |
Brew K, Nagase H. The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity. Biochimica Et Biophysica Acta. 1803: 55-71. PMID 20080133 DOI: 10.1016/J.Bbamcr.2010.01.003 |
0.748 |
|
| 2010 |
Bitler A, Perugia E, Solomonov I, Visse R, Orgel J, Nagase H, Cohen S, Sagi I. Influence of Matrix Metalloprotease on the Flexibility of Type I Collagen Fibrils Studied By Atomic Force Microscopy Biophysical Journal. 98: 29a. DOI: 10.1016/J.Bpj.2009.12.172 |
0.445 |
|
| 2009 |
Troeberg L, Fushimi K, Scilabra SD, Nakamura H, Dive V, Thøgersen IB, Enghild JJ, Nagase H. The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3. Matrix Biology : Journal of the International Society For Matrix Biology. 28: 463-9. PMID 19643179 DOI: 10.1016/J.Matbio.2009.07.005 |
0.48 |
|
| 2009 |
Nuti E, Casalini F, Avramova SI, Santamaria S, Cercignani G, Marinelli L, La Pietra V, Novellino E, Orlandini E, Nencetti S, Tuccinardi T, Martinelli A, Lim NH, Visse R, Nagase H, et al. N-O-isopropyl sulfonamido-based hydroxamates: Design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis Journal of Medicinal Chemistry. 52: 4757-4773. PMID 19606871 DOI: 10.1021/Jm900261F |
0.621 |
|
| 2009 |
Miller MC, Manning HB, Jain A, Troeberg L, Dudhia J, Essex D, Sandison A, Seiki M, Nanchahal J, Nagase H, Itoh Y. Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis. Arthritis and Rheumatism. 60: 686-97. PMID 19248098 DOI: 10.1002/Art.24331 |
0.572 |
|
| 2009 |
Dabert-Gay AS, Czarny B, Lajeunesse E, Thai R, Nagase H, Dive V. Covalent modification of matrix metalloproteinases by a photoaffinity probe: influence of nucleophilicity and flexibility of the residue in position 241. Bioconjugate Chemistry. 20: 367-75. PMID 19138112 DOI: 10.1021/Bc800478B |
0.6 |
|
| 2009 |
Murphy G, Nagase H. Progress in matrix metalloproteinase research Molecular Aspects of Medicine. 29: 290-308. PMID 18619669 DOI: 10.1016/J.Mam.2008.05.002 |
0.529 |
|
| 2009 |
Han S, Phillips C, McBride D, Visse R, Nagase H, Losert W, Leikin S. Bending rigidity of type I collagen homotrimer fibrils Biophysical Journal. 96: 38a. DOI: 10.1016/J.Bpj.2008.12.091 |
0.329 |
|
| 2008 |
Nagase H, Fushimi K. Elucidating the function of non catalytic domains of collagenases and aggrecanases Connective Tissue Research. 49: 169-174. PMID 18661336 DOI: 10.1080/03008200802151698 |
0.445 |
|
| 2008 |
Troeberg L, Fushimi K, Khokha R, Emonard H, Ghosh P, Nagase H. Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3515-24. PMID 18632849 DOI: 10.1096/Fj.08-112680 |
0.498 |
|
| 2008 |
Durigova M, Soucy P, Fushimi K, Nagase H, Mort JS, Roughley PJ. Characterization of an ADAMTS-5-mediated cleavage site in aggrecan in OSM-stimulated bovine cartilage. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 16: 1245-52. PMID 18372197 DOI: 10.1016/J.Joca.2008.02.013 |
0.372 |
|
| 2008 |
Itoh Y, Ito N, Nagase H, Seiki M. The second dimer interface of MT1-MMP, the transmembrane domain, is essential for ProMMP-2 activation on the cell surface. The Journal of Biological Chemistry. 283: 13053-62. PMID 18337248 DOI: 10.1074/Jbc.M709327200 |
0.573 |
|
| 2008 |
Murphy G, Nagase H. Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: Destruction or repair? Nature Clinical Practice Rheumatology. 4: 128-135. PMID 18253109 DOI: 10.1038/Ncprheum0727 |
0.581 |
|
| 2008 |
Fushimi K, Troeberg L, Nakamura H, Lim NH, Nagase H. Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity. The Journal of Biological Chemistry. 283: 6706-16. PMID 18156631 DOI: 10.1074/Jbc.M708647200 |
0.344 |
|
| 2008 |
Jacobsen J, Visse R, Sørensen HP, Enghild JJ, Brew K, Wewer UM, Nagase H. Catalytic properties of ADAM12 and its domain deletion mutants. Biochemistry. 47: 537-47. PMID 18081311 DOI: 10.1021/Bi701629C |
0.675 |
|
| 2008 |
Lauer-Fields JL, Spicer TP, Chase PS, Cudic M, Burstein GD, Nagase H, Hodder P, Fields GB. Screening of potential a disintegrin and metalloproteinase with thrombospondin motifs-4 inhibitors using a collagen model fluorescence resonance energy transfer substrate. Analytical Biochemistry. 373: 43-51. PMID 17949675 DOI: 10.1016/J.Ab.2007.09.014 |
0.468 |
|
| 2008 |
Itoh Y, Ito N, Nagase H, Seiki M. Homophilic complex formation is prerequisite for MT1-MMP to degrade type-I collagen on the cell surface International Journal of Experimental Pathology. 85: A42-A43. DOI: 10.1111/J.0959-9673.2004.369Bd.X |
0.627 |
|
| 2008 |
Talbot CB, Lever MJ, Benninger RKP, Mcginty J, Requejo-Isidro J, Elson DS, French PMW, Sandison A, Wallace AL, Nagase H, Itoh Y, Saklatvala J, Vincent T. Fluorescence lifetime imaging of articular cartilage International Journal of Experimental Pathology. 85. DOI: 10.1111/J.0959-9673.2004.369Ao.X |
0.324 |
|
| 2008 |
Han S, Makareeva E, McBride DJ, Phillips CL, Schwarze U, Pace JM, Byers PH, Visse R, Nagase H, Leikin S. Type I collagen homotrimers may alter tissue remodeling Matrix Biology. 27: 29. DOI: 10.1016/J.Matbio.2008.09.296 |
0.36 |
|
| 2008 |
Nakamura H, Vo P, Lim NH, Liu K, Nagase H, Bou-Gharios G. Does TIMP-3 protect articular cartilage in OA model Matrix Biology. 27: 27-28. DOI: 10.1016/J.Matbio.2008.09.291 |
0.383 |
|
| 2008 |
To WS, Nagase H, Midwood KS. Regulation of fibronectin matrix assembly by tenascin-C Matrix Biology. 27: 14. DOI: 10.1016/J.Matbio.2008.09.237 |
0.414 |
|
| 2008 |
Nagase H, Murphy G. Tailoring TIMPs for selective metalloproteinase inhibition The Cancer Degradome: Proteases and Cancer Biology. 787-810. DOI: 10.1007/978-0-387-69057-5_37 |
0.492 |
|
| 2007 |
Troeberg L, Nagase H. Analysis of TIMP expression and activity Methods in Molecular Medicine. 135: 251-267. PMID 17951664 DOI: 10.1007/978-1-59745-401-8_16 |
0.563 |
|
| 2007 |
Kopitz C, Gerg M, Bandapalli OR, Ister D, Pennington CJ, Hauser S, Flechsig C, Krell HW, Antolovic D, Brew K, Nagase H, Stangl M, von Weyhern CW, Brücher BL, Brand K, et al. Tissue inhibitor of metalloproteinases-1 promotes liver metastasis by induction of hepatocyte growth factor signaling. Cancer Research. 67: 8615-23. PMID 17875701 DOI: 10.1158/0008-5472.Can-07-0232 |
0.645 |
|
| 2007 |
Ries C, Pitsch T, Mentele R, Zahler S, Egea V, Nagase H, Jochum M. Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells: (Auto-)catalytic activation and resistance to inhibition by TIMP-1 Biochemical Journal. 405: 547-558. PMID 17489740 DOI: 10.1042/Bj20070191 |
0.577 |
|
| 2007 |
Gendron C, Kashiwagi M, Ngee HL, Enghild JJ, Thøgersen IB, Hughes C, Caterson B, Nagase H. Proteolytic activities of human ADAMTS-5: Comparative studies with ADAMTS-4 Journal of Biological Chemistry. 282: 18294-18306. PMID 17430884 DOI: 10.1074/Jbc.M701523200 |
0.391 |
|
| 2007 |
Lauer-Fields JL, Minond D, Sritharan T, Kashiwagi M, Nagase H, Fields GB. Substrate conformation modulates aggrecanase (ADAMTS-4) affinity and sequence specificity. Suggestion of a common topological specificity for functionally diverse proteases. The Journal of Biological Chemistry. 282: 142-50. PMID 17095512 DOI: 10.1074/Jbc.M605236200 |
0.383 |
|
| 2007 |
Ries C, Pitsch T, Mentele R, Zahler S, Egea V, Nagase H, Jochum M. Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells Biochemical Journal. DOI: 10.5282/Ubm/Epub.14390 |
0.578 |
|
| 2007 |
Nagase H. TARGETING MMPS AND ADAMTSS IN OSTEOARTHRITIS Osteoarthritis and Cartilage. 15: C2. DOI: 10.1016/S1063-4584(07)61606-9 |
0.445 |
|
| 2006 |
Minond D, Lauer-Fields JL, Cudic M, Overall CM, Pei D, Brew K, Visse R, Nagase H, Fields GB. The roles of substrate thermal stability and P2 and P1' subsite identity on matrix metalloproteinase triple-helical peptidase activity and collagen specificity. The Journal of Biological Chemistry. 281: 38302-13. PMID 17065155 DOI: 10.1074/Jbc.M606004200 |
0.753 |
|
| 2006 |
Itoh Y, Ito N, Nagase H, Evans RD, Bird SA, Seiki M. Cell surface collagenolysis requires homodimerization of the membrane-bound collagenase MT1-MMP. Molecular Biology of the Cell. 17: 5390-9. PMID 17050733 DOI: 10.1091/Mbc.E06-08-0740 |
0.555 |
|
| 2006 |
Iyer S, Visse R, Nagase H, Acharya KR. Crystal structure of an active form of human MMP-1. Journal of Molecular Biology. 362: 78-88. PMID 16890240 DOI: 10.1016/J.Jmb.2006.06.079 |
0.625 |
|
| 2006 |
Pinto AF, Terra RM, Guimarães JA, Kashiwagi M, Nagase H, Serrano SM, Fox JW. Structural features of the reprolysin atrolysin C and tissue inhibitors of metalloproteinases (TIMPs) interaction. Biochemical and Biophysical Research Communications. 347: 641-8. PMID 16842758 DOI: 10.1016/J.Bbrc.2006.06.143 |
0.523 |
|
| 2006 |
Wang WM, Ge G, Lim NH, Nagase H, Greenspan DS. TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2. The Biochemical Journal. 398: 515-9. PMID 16771712 DOI: 10.1042/Bj20060630 |
0.6 |
|
| 2006 |
English JL, Kassiri Z, Koskivirta I, Atkinson SJ, Di Grappa M, Soloway PD, Nagase H, Vuorio E, Murphy G, Khokha R. Individual Timp deficiencies differentially impact pro-MMP-2 activation. The Journal of Biological Chemistry. 281: 10337-46. PMID 16469749 DOI: 10.1074/Jbc.M512009200 |
0.633 |
|
| 2006 |
Nagase H, Visse R, Murphy G. Structure and function of matrix metalloproteinases and TIMPs. Cardiovascular Research. 69: 562-73. PMID 16405877 DOI: 10.1016/J.Cardiores.2005.12.002 |
0.595 |
|
| 2006 |
Ogata Y, Matono K, Nakajima M, Sasatomi T, Mizobe T, Nagase H, Shirouzu K. Efficacy of the MMP inhibitor MMI270 against lung metastasis following removal of orthotopically transplanted human colon cancer in rat. International Journal of Cancer. 118: 215-21. PMID 16003755 DOI: 10.1002/Ijc.21285 |
0.305 |
|
| 2006 |
Salvesen GS, Murphy G, Nagase H. The trap hypothesis: alpha2M and protease inhibition Biochemical Journal. 28: 46-48. DOI: 10.1042/Bj2006C003 |
0.341 |
|
| 2006 |
KUZNETSOVA N, MAKAREEVA E, CABRAL W, VISSE R, NAGASE H, MARINI J, LEIKIN S. Chain register shift in type I collagen alters MMP1 cleavage Matrix Biology. 25: S75-S75. DOI: 10.1016/J.Matbio.2006.08.206 |
0.54 |
|
| 2005 |
Abraham D, Ponticos M, Nagase H. Connective tissue remodeling: cross-talk between endothelins and matrix metalloproteinases. Current Vascular Pharmacology. 3: 369-79. PMID 16248781 DOI: 10.2174/157016105774329480 |
0.572 |
|
| 2005 |
Wei S, Kashiwagi M, Kota S, Xie Z, Nagase H, Brew K. Reactive site mutations in tissue inhibitor of metalloproteinase-3 disrupt inhibition of matrix metalloproteinases but not tumor necrosis factor-alpha-converting enzyme. The Journal of Biological Chemistry. 280: 32877-82. PMID 16079149 DOI: 10.1074/Jbc.C500220200 |
0.746 |
|
| 2005 |
Anilkumar N, Uekita T, Couchman JR, Nagase H, Seiki M, Itoh Y. Palmitoylation at Cys574 is essential for MT1-MMP to promote cell migration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1326-8. PMID 15946988 DOI: 10.1096/Fj.04-3651Fje |
0.601 |
|
| 2005 |
Bai S, Thummel R, Godwin AR, Nagase H, Itoh Y, Li L, Evans R, McDermott J, Seiki M, Sarras MP. Matrix metalloproteinase expression and function during fin regeneration in zebrafish: analysis of MT1-MMP, MMP2 and TIMP2. Matrix Biology : Journal of the International Society For Matrix Biology. 24: 247-60. PMID 15935631 DOI: 10.1016/J.Matbio.2005.03.007 |
0.63 |
|
| 2005 |
Jozic D, Bourenkov G, Lim NH, Visse R, Nagase H, Bode W, Maskos K. X-ray structure of human proMMP-1: new insights into procollagenase activation and collagen binding. The Journal of Biological Chemistry. 280: 9578-85. PMID 15611040 DOI: 10.1074/Jbc.M411084200 |
0.503 |
|
| 2005 |
Nagase H, Visse R, Kashiwagi M, Gendron C, Itoh Y. Collagenases and aggrecanases: understanding the role of non-catalytic domains in cartilage matrix breakdown Arthritis Research & Therapy. 7: 1-1. DOI: 10.1186/Ar1517 |
0.644 |
|
| 2004 |
Troeberg L, Nagase H. Monitoring metalloproteinase activity using synthetic fluorogenic substrates Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. PMID 18429258 DOI: 10.1002/0471140864.Ps2116S33 |
0.53 |
|
| 2004 |
Troeberg L, Nagase H. Zymography of metalloproteinases Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. PMID 18429257 DOI: 10.1002/0471140864.Ps2115S33 |
0.437 |
|
| 2004 |
Lauer-Fields JL, Nagase H, Fields GB. Development of a solid-phase assay for analysis of matrix metalloproteinase activity. Journal of Biomolecular Techniques : Jbt. 15: 305-16. PMID 15585827 |
0.485 |
|
| 2004 |
Emonard H, Bellon G, Troeberg L, Berton A, Robinet A, Henriet P, Marbaix E, Kirkegaard K, Patthy L, Eeckhout Y, Nagase H, Hornebeck W, Courtoy PJ. Low density lipoprotein receptor-related protein mediates endocytic clearance of pro-MMP-2.TIMP-2 complex through a thrombospondin-independent mechanism. The Journal of Biological Chemistry. 279: 54944-51. PMID 15489233 DOI: 10.1074/Jbc.M406792200 |
0.628 |
|
| 2004 |
Minond D, Lauer-Fields JL, Nagase H, Fields GB. Matrix metalloproteinase triple-helical peptidase activities are differentially regulated by substrate stability. Biochemistry. 43: 11474-81. PMID 15350133 DOI: 10.1021/Bi048938I |
0.626 |
|
| 2004 |
Chung L, Dinakarpandian D, Yoshida N, Lauer-Fields JL, Fields GB, Visse R, Nagase H. Collagenase unwinds triple-helical collagen prior to peptide bond hydrolysis. The Embo Journal. 23: 3020-30. PMID 15257288 DOI: 10.1038/Sj.Emboj.7600318 |
0.581 |
|
| 2004 |
Sultan S, Gosling M, Nagase H, Powell JT. Shear stress-induced shedding of soluble intercellular adhesion molecule-1 from saphenous vein endothelium. Febs Letters. 564: 161-5. PMID 15094060 DOI: 10.1016/S0014-5793(04)00337-0 |
0.529 |
|
| 2004 |
Murphy F, Waung J, Collins J, Arthur MJ, Nagase H, Mann D, Benyon RC, Iredale JP. N-Cadherin cleavage during activated hepatic stellate cell apoptosis is inhibited by tissue inhibitor of metalloproteinase-1. Comparative Hepatology. 3: S8. PMID 14960160 DOI: 10.1186/1476-5926-2-S1-S8 |
0.453 |
|
| 2004 |
Zhao H, Bernardo MM, Osenkowski P, Sohail A, Pei D, Nagase H, Kashiwagi M, Soloway PD, DeClerck YA, Fridman R. Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation. The Journal of Biological Chemistry. 279: 8592-601. PMID 14681236 DOI: 10.1074/Jbc.M308708200 |
0.566 |
|
| 2004 |
Conant K, St Hillaire C, Nagase H, Visse R, Gary D, Haughey N, Anderson C, Turchan J, Nath A. Matrix metalloproteinase 1 interacts with neuronal integrins and stimulates dephosphorylation of Akt. The Journal of Biological Chemistry. 279: 8056-62. PMID 14679206 DOI: 10.1074/Jbc.M307051200 |
0.496 |
|
| 2004 |
Kashiwagi M, Enghild JJ, Gendron C, Hughes C, Caterson B, Itoh Y, Nagase H. Altered Proteolytic Activities of ADAMTS-4 Expressed by C-terminal Processing Journal of Biological Chemistry. 279: 10109-10119. PMID 14662755 DOI: 10.1074/Jbc.M312123200 |
0.406 |
|
| 2003 |
Liu J, Xiong W, Baca-Regen L, Nagase H, Baxter BT. Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells. Journal of Vascular Surgery. 38: 1376-83. PMID 14681644 DOI: 10.1016/S0741-5214(03)01022-X |
0.592 |
|
| 2003 |
Gendron C, Kashiwagi M, Hughes C, Caterson B, Nagase H. TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors Febs Letters. 555: 431-436. PMID 14675751 DOI: 10.1016/S0014-5793(03)01295-X |
0.464 |
|
| 2003 |
Fowlkes JL, Serra DM, Bunn RC, Thrailkill KM, Enghild JJ, Nagase H. Regulation of insulin-like growth factor (IGF)-I action by matrix metalloproteinase-3 involves selective disruption of IGF-I/IGF-binding protein-3 complexes. Endocrinology. 145: 620-6. PMID 14605000 DOI: 10.1210/En.2003-0636 |
0.424 |
|
| 2003 |
Nagase H, Brew K. Designing TIMP (tissue inhibitor of metalloproteinases) variants that are selective metalloproteinase inhibitors. Biochemical Society Symposium. 201-12. PMID 14587293 DOI: 10.1042/Bss0700201 |
0.771 |
|
| 2003 |
Lauer-Fields JL, Kele P, Sui G, Nagase H, Leblanc RM, Fields GB. Analysis of matrix metalloproteinase triple-helical peptidase activity with substrates incorporating fluorogenic L- or D-amino acids. Analytical Biochemistry. 321: 105-15. PMID 12963061 DOI: 10.1016/S0003-2697(03)00460-3 |
0.564 |
|
| 2003 |
Zhang J, Bai S, Zhang X, Nagase H, Sarras MP. The expression of gelatinase A (MMP-2) is required for normal development of zebrafish embryos. Development Genes and Evolution. 213: 456-63. PMID 12898250 DOI: 10.1007/S00427-003-0346-4 |
0.588 |
|
| 2003 |
Zhang J, Bai S, Zhang X, Nagase H, Sarras MP. The expression of novel membrane-type matrix metalloproteinase isoforms is required for normal development of zebrafish embryos. Matrix Biology : Journal of the International Society For Matrix Biology. 22: 279-93. PMID 12853038 DOI: 10.1016/S0945-053X(03)00020-9 |
0.591 |
|
| 2003 |
Troeberg L, Nagase H. Measurement of matrix metalloproteinase activities in the medium of cultured synoviocytes using zymography Methods in Molecular Biology (Clifton, N.J.). 225: 77-87. PMID 12769476 DOI: 10.1385/1-59259-374-7:77 |
0.457 |
|
| 2003 |
Zhang J, Bai S, Tanase C, Nagase H, Sarras MP. The expression of tissue inhibitor of metalloproteinase 2 (TIMP-2) is required for normal development of zebrafish embryos. Development Genes and Evolution. 213: 382-9. PMID 12736828 DOI: 10.1007/S00427-003-0333-9 |
0.553 |
|
| 2003 |
Visse R, Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry Circulation Research. 92: 827-839. PMID 12730128 DOI: 10.1161/01.Res.0000070112.80711.3D |
0.595 |
|
| 2003 |
Nagase H, Kashiwagi M. Aggrecanases and cartilage matrix degradation Arthritis Research and Therapy. 5: 94-103. PMID 12718749 DOI: 10.1186/Ar630 |
0.54 |
|
| 2003 |
Ahonen M, Poukkula M, Baker AH, Kashiwagi M, Nagase H, Eriksson JE, Kähäri VM. Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors. Oncogene. 22: 2121-34. PMID 12687014 DOI: 10.1038/Sj.Onc.1206292 |
0.407 |
|
| 2003 |
Lauer-Fields JL, Sritharan T, Stack MS, Nagase H, Fields GB. Selective hydrolysis of triple-helical substrates by matrix metalloproteinase-2 and -9. The Journal of Biological Chemistry. 278: 18140-5. PMID 12642591 DOI: 10.1074/Jbc.M211330200 |
0.605 |
|
| 2003 |
Wei S, Chen Y, Chung L, Nagase H, Brew K. Protein engineering of the tissue inhibitor of metalloproteinase 1 (TIMP-1) inhibitory domain. In search of selective matrix metalloproteinase inhibitors. The Journal of Biological Chemistry. 278: 9831-4. PMID 12515831 DOI: 10.1074/Jbc.M211793200 |
0.755 |
|
| 2003 |
Nagase H, Gendron C, Kashiwagi M. TIMP-3 inhibits aggrecan breakdown in pig articular cartilage stimulated with IL-1 Arthritis Research & Therapy. 5: 48-48. DOI: 10.1186/Ar849 |
0.628 |
|
| 2003 |
Murphy F, Zhou X, Issa R, Hussain H, Waung J, Patel N, Collins J, Brew K, Nagase H, Arthur M, Benyon R, Iredale J. The Balance of TIMPs and MMP-2 Determines Hepatic Stellate Cell Fate during Recovery from Liver Fibrosis Clinical Science. 104: 2P-3P. DOI: 10.1042/cs104002Pc |
0.593 |
|
| 2002 |
Troeberg L, Tanaka M, Wait R, Shi YE, Brew K, Nagase H. E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A). Biochemistry. 41: 15025-35. PMID 12475252 DOI: 10.1021/Bi026454L |
0.756 |
|
| 2002 |
Itoh Y, Nagase H. Matrix metalloproteinases in cancer Essays in Biochemistry. 38: 21-36. PMID 12463159 DOI: 10.1042/Bse0380021 |
0.56 |
|
| 2002 |
Nagase H, Brew K. Engineering of tissue inhibitor of metalloproteinases mutants as potential therapeutics. Arthritis Research. 4: S51-61. PMID 12110123 DOI: 10.1186/Ar573 |
0.753 |
|
| 2002 |
Kang T, Nagase H, Pei D. Activation of membrane-type matrix metalloproteinase 3 zymogen by the proprotein convertase furin in the trans-Golgi network Cancer Research. 62: 675-681. PMID 11830519 |
0.538 |
|
| 2002 |
Murphy FR, Issa R, Zhou X, Ratnarajah S, Nagase H, Arthur MJ, Benyon C, Iredale JP. Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. The Journal of Biological Chemistry. 277: 11069-76. PMID 11796725 DOI: 10.1074/Jbc.M111490200 |
0.515 |
|
| 2002 |
Yamauchi K, Ogata Y, Nagase H, Shirouzu K. Inhibition of liver metastasis from orthotopically implanted colon cancer in nude mice by transfection of the TIMP-1 gene into KM12SM cells. Surgery Today. 31: 791-8. PMID 11686557 DOI: 10.1007/S005950170049 |
0.398 |
|
| 2002 |
Murphy F, Issa R, Zhou X, Hussain H, Ratnarajah S, Soloway P, Nagase H, Mjp A, Benyon R, Iredale J. Inhibition of Apoptosis of Activated Hepatic Stellate Cells by Timp-1 is Mediated via Effects on Mmp Inhibition: Implications for Reversibility of Liver Fibrosis Clinical Science. 103: 40P-40P. DOI: 10.1042/Cs103040P |
0.463 |
|
| 2002 |
Nagase H, Chung L, Brew K. Mechanisms of action of collagenases and TIMPs Biochemical Society Transactions. 30: A21-A21. DOI: 10.1042/Bst030A021A |
0.566 |
|
| 2001 |
Nagase H. Metalloproteases Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. PMID 18429165 DOI: 10.1002/0471140864.Ps2104S24 |
0.311 |
|
| 2001 |
Ogata Y, Miura K, Ohkita A, Nagase H, Shirouzu K. Imbalance between matrix metalloproteinase 9 and tissue inhibitor of metalloproteinases 1 expression by tumor cells implicated in liver metastasis from colorectal carcinoma. The Kurume Medical Journal. 48: 211-218. PMID 11680936 DOI: 10.2739/Kurumemedj.48.211 |
0.479 |
|
| 2001 |
Nollendorfs A, Greiner TC, Nagase H, Baxter BT. The expression and localization of membrane type-1 matrix metalloproteinase in human abdominal aortic aneurysms. Journal of Vascular Surgery. 34: 316-22. PMID 11496285 DOI: 10.1067/Mva.2001.115962 |
0.573 |
|
| 2001 |
Stricker TP, Dumin JA, Dickeson SK, Chung L, Nagase H, Parks WC, Santoro SA. Structural analysis of the alpha(2) integrin I domain/procollagenase-1 (matrix metalloproteinase-1) interaction. The Journal of Biological Chemistry. 276: 29375-81. PMID 11359774 DOI: 10.1074/Jbc.M102217200 |
0.579 |
|
| 2001 |
Lauer-Fields JL, Broder T, Sritharan T, Chung L, Nagase H, Fields GB. Kinetic analysis of matrix metalloproteinase activity using fluorogenic triple-helical substrates Biochemistry. 40: 5795-5803. PMID 11341845 DOI: 10.1021/Bi0101190 |
0.639 |
|
| 2001 |
Tamura T, Kosaka N, Ishiwa J, Sato T, Nagase H, Ito A. Rhein, an active metabolite of diacerein, down-regulates the production of pro-matrix metalloproteinases-1, -3, -9 and -13 and up-regulates the production of tissue inhibitor of metalloproteinase-1 in cultured rabbit articular chondrocytes. Osteoarthritis and Cartilage. 9: 257-63. PMID 11300749 DOI: 10.1053/Joca.2000.0383 |
0.567 |
|
| 2001 |
Kashiwagi M, Tortorella M, Nagase H, Brew K. TIMP-3 Is a Potent Inhibitor of Aggrecanase 1 (ADAM-TS4) and Aggrecanase 2 (ADAM-TS5) Journal of Biological Chemistry. 276: 12501-12504. PMID 11278243 DOI: 10.1074/Jbc.C000848200 |
0.734 |
|
| 2001 |
Shimokawa K, Nagase H. Purification of MMPs and TIMPs Methods in Molecular Biology (Clifton, N.J.). 151: 275-304. PMID 11217306 DOI: 10.1007/978-1-60327-299-5_8 |
0.53 |
|
| 2000 |
Inuzuka K, Ogata Y, Nagase H, Shirouzu K. Significance of Coexpression of Urokinase-type Plasminogen Activator, and Matrix Metalloproteinase 3 (Stromelysin) and 9 (Gelatinase B) in Colorectal Carcinoma Journal of Surgical Research. 93: 211-218. PMID 11027463 DOI: 10.1006/Jsre.2000.5952 |
0.603 |
|
| 2000 |
Lauer-Fields JL, Nagase H, Fields GB. Use of Edman degradation sequence analysis and matrix-assisted laser desorption/ionization mass spectrometry in designing substrates for matrix metalloproteinases Journal of Chromatography A. 890: 117-125. PMID 10976799 DOI: 10.1016/S0021-9673(00)00396-4 |
0.586 |
|
| 2000 |
Chung L, Shimokawa K, Dinakarpandian D, Grams F, Fields GB, Nagase H. Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity. The Journal of Biological Chemistry. 275: 29610-7. PMID 10871619 DOI: 10.1074/Jbc.M004039200 |
0.611 |
|
| 2000 |
Lauer-Fields JL, Tuzinski KA, Shimokawa KI, Nagase H, Fields GB. Hydrolysis of triple-helical collagen peptide models by matrix metalloproteinases Journal of Biological Chemistry. 275: 13282-13290. PMID 10788434 DOI: 10.1074/Jbc.275.18.13282 |
0.617 |
|
| 2000 |
Brew K, Dinakarpandian D, Nagase H. Tissue inhibitors of metalloproteinases: Evolution, structure and function Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1477: 267-283. PMID 10708863 DOI: 10.1016/S0167-4838(99)00279-4 |
0.757 |
|
| 2000 |
Ottl J, Gabriel D, Murphy G, Knäuper V, Tominaga Y, Nagase H, Kröger M, Tschesche H, Bode W, Moroder L. Recognition and catabolism of synthetic heterotrimeric collagen peptides by matrix metalloproteinases. Chemistry & Biology. 7: 119-32. PMID 10662694 DOI: 10.1016/S1074-5521(00)00077-6 |
0.555 |
|
| 2000 |
Kostoulas G, Lang A, Nagase H, Baici A. Erratum to: Stimulation of angiogenesis through cathepsin B inactivation of the tissue inhibitors of matrix metalloproteinases (FEBS 22347) Febs Letters. 466: 394-394. DOI: 10.1016/S0014-5793(99)01266-1 |
0.503 |
|
| 1999 |
Ruiz S, Henschen-Edman AH, Nagase H, Tenner AJ. Digestion of C1q collagen-like domain with MMPs-1,-2,-3, and -9 further defines the sequence involved in the stimulation of neutrophil superoxide production Journal of Leukocyte Biology. 66: 416-422. PMID 10496311 DOI: 10.1002/Jlb.66.3.416 |
0.492 |
|
| 1999 |
Benbow U, Schoenermark MP, Mitchell TI, Rutter JL, Shimokawa K, Nagase H, Brinckerhoff CE. A novel host/tumor cell interaction activates matrix metalloproteinase 1 and mediates invasion through type I collagen. The Journal of Biological Chemistry. 274: 25371-8. PMID 10464264 DOI: 10.1074/Jbc.274.36.25371 |
0.5 |
|
| 1999 |
Abbaszade I, Liu RQ, Yang F, Rosenfeld SA, Ross OH, Link JR, Ellis DM, Tortorella MD, Pratta MA, Hollis JM, Wynn R, Duke JL, George HJ, Hillman MC, Murphy K, ... ... Nagase H, et al. Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family. The Journal of Biological Chemistry. 274: 23443-50. PMID 10438522 DOI: 10.1074/Jbc.274.33.23443 |
0.534 |
|
| 1999 |
Kostoulas G, Lang A, Nagase H, Baici A. Stimulation of angiogenesis through cathepsin B inactivation of the tissue inhibitors of matrix metalloproteinases. Febs Letters. 455: 286-90. PMID 10437790 DOI: 10.1016/S0014-5793(99)00897-2 |
0.603 |
|
| 1999 |
Nagase H, Woessner JF. Matrix metalloproteinases. The Journal of Biological Chemistry. 274: 21491-4. PMID 10419448 DOI: 10.1074/jbc.274.31.21491 |
0.477 |
|
| 1999 |
Fowlkes JL, Serra DM, Nagase H, Thrailkill KM. MMPs are IGFBP-degrading proteinases: implications for cell proliferation and tissue growth. Annals of the New York Academy of Sciences. 878: 696-9. PMID 10415811 DOI: 10.1111/J.1749-6632.1999.Tb07765.X |
0.528 |
|
| 1999 |
Dolo V, Ginestra A, Cassará D, Ghersi G, Nagase H, Vittorelli ML. Shed membrane vesicles and selective localization of gelatinases and MMP-9/TIMP-1 complexes. Annals of the New York Academy of Sciences. 878: 497-9. PMID 10415753 DOI: 10.1111/J.1749-6632.1999.Tb07707.X |
0.462 |
|
| 1999 |
Hahn-Dantona E, Ramos-DeSimone N, Sipley J, Nagase H, French DL, Quigley JP. Activation of proMMP-9 by a plasmin/MMP-3 cascade in a tumor cell model. Regulation by tissue inhibitors of metalloproteinases. Annals of the New York Academy of Sciences. 878: 372-87. PMID 10415742 DOI: 10.1111/J.1749-6632.1999.Tb07696.X |
0.615 |
|
| 1999 |
Bode W, Fernandez-Catalan C, Grams F, Gomis-Rüth FX, Nagase H, Tschesche H, Maskos K. Insights into MMP-TIMP interactions. Annals of the New York Academy of Sciences. 878: 73-91. PMID 10415721 DOI: 10.1111/J.1749-6632.1999.Tb07675.X |
0.611 |
|
| 1999 |
Nagase H, Meng Q, Malinovskii V, Huang W, Chung L, Bode W, Maskos K, Brew K. Engineering of selective TIMPs Annals of the New York Academy of Sciences. 878: 1-11. PMID 10415716 DOI: 10.1111/J.1749-6632.1999.Tb07670.X |
0.727 |
|
| 1999 |
Bode W, Fernandez-Catalan C, Tschesche H, Grams F, Nagase H, Maskos K. Structural properties of matrix metalloproteinases Cellular and Molecular Life Sciences. 55: 639-652. PMID 10357232 DOI: 10.1007/S000180050320 |
0.617 |
|
| 1999 |
Tortorella MD, Burn TC, Pratta MA, Abbaszade I, Hollis JM, Liu R, Rosenfeld SA, Copeland RA, Decicco CP, Wynn R, Rockwell A, Yang F, Duke JL, Solomon K, George H, ... ... Nagase H, et al. Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins. Science (New York, N.Y.). 284: 1664-6. PMID 10356395 DOI: 10.1126/Science.284.5420.1664 |
0.37 |
|
| 1999 |
Ramos-DeSimone N, Hahn-Dantona E, Sipley J, Nagase H, French DL, Quigley JP. Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion. The Journal of Biological Chemistry. 274: 13066-76. PMID 10224058 DOI: 10.1074/Jbc.274.19.13066 |
0.568 |
|
| 1999 |
Bode W, Fernandez-Catalan C, Nagase H, Maskos K. Endoproteinase-protein inhibitor interactions. Apmis. 107: 3-10. PMID 10190274 DOI: 10.1111/J.1699-0463.1999.Tb01520.X |
0.505 |
|
| 1999 |
Meng Q, Malinovskii V, Huang W, Hu Y, Chung L, Nagase H, Bode W, Maskos K, Brew K. Residue 2 of TIMP-1 is a major determinant of affinity and specificity for matrix metalloproteinases but effects of substitutions do not correlate with those of the corresponding P1' residue of substrate Journal of Biological Chemistry. 274: 10184-10189. PMID 10187802 DOI: 10.1074/Jbc.274.15.10184 |
0.764 |
|
| 1999 |
Kremer EA, Chen Y, Suzuki K, Nagase H, Gorski JP. Hydroxyapatite induces autolytic degradation and inactivation of matrix metalloproteinase-1 and -3. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 13: 1890-902. PMID 9844107 DOI: 10.1359/Jbmr.1998.13.12.1890 |
0.595 |
|
| 1998 |
Nagase H. Cell surface activation of progelatinase A (proMMP-2) and cell migration. Cell Research. 8: 179-86. PMID 9791731 DOI: 10.1038/Cr.1998.18 |
0.603 |
|
| 1998 |
Davis V, Persidskaia R, Baca-Regen L, Itoh Y, Nagase H, Persidsky Y, Ghorpade A, Baxter BT. Matrix metalloproteinase-2 production and its binding to the matrix are increased in abdominal aortic aneurysms. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 1625-33. PMID 9763536 DOI: 10.1161/01.Atv.18.10.1625 |
0.609 |
|
| 1998 |
Itoh Y, Ito A, Iwata K, Tanzawa K, Mori Y, Nagase H. Plasma membrane-bound tissue inhibitor of metalloproteinases (TIMP)-2 specifically inhibits matrix metalloproteinase 2 (gelatinase A) activated on the cell surface. The Journal of Biological Chemistry. 273: 24360-7. PMID 9733724 DOI: 10.1074/Jbc.273.38.24360 |
0.622 |
|
| 1998 |
Arumugam S, Hemme CL, Yoshida N, Suzuki K, Nagase H, Berjanskii M, Wu B, Van Doren SR. TIMP-1 contact sites and perturbations of stromelysin 1 mapped by NMR and a paramagnetic surface probe Biochemistry. 37: 9650-9657. PMID 9657677 DOI: 10.1021/Bi980128H |
0.515 |
|
| 1998 |
Glant TT, Cs-Szabó G, Nagase H, Jacobs JJ, Mikecz K. Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage. Arthritis and Rheumatism. 41: 1007-18. PMID 9627010 DOI: 10.1002/1529-0131(199806)41:6<1007::Aid-Art7>3.0.Co;2-6 |
0.329 |
|
| 1998 |
Suzuki K, Kan CC, Hung W, Gehring MR, Brew K, Nagase H. Expression of human pro-matrix metalloproteinase 3 that lacks the N-terminal 34 residues in Escherichia coli autoactivation and interaction with tissue inhibitor of metalloproteinase 1 (TIMP-1) Biological Chemistry. 379: 185-191. PMID 9524070 DOI: 10.1515/Bchm.1998.379.2.185 |
0.721 |
|
| 1998 |
Ito A, Yamada M, Sato T, Sanekata K, Sato H, Seiki M, Nagase H, Mori Y. Calmodulin antagonists increase the expression of membrane-type-1 matrix metalloproteinase in human uterine cervical fibroblasts. European Journal of Biochemistry. 251: 353-8. PMID 9492304 DOI: 10.1046/J.1432-1327.1998.2510353.X |
0.597 |
|
| 1998 |
Kusano K, Miyaura C, Inada M, Tamura T, Ito A, Nagase H, Kamoi K, Suda T. Regulation of matrix metalloproteinases (MMP-2, -3, -9, and -13) by interleukin-1 and interleukin-6 in mouse calvaria: association of MMP induction with bone resorption. Endocrinology. 139: 1338-45. PMID 9492070 DOI: 10.1210/Endo.139.3.5818 |
0.487 |
|
| 1998 |
Müller JC, von Roedern EG, Grams F, Nagase H, Moroder L. Non-peptidic cysteine derivatives as inhibitors of matrix metalloproteinases. Biological Chemistry. 378: 1475-80. PMID 9461346 DOI: 10.1515/Bchm.1997.378.12.1475 |
0.593 |
|
| 1998 |
Fowlkes JL, Thrailkill KM, Serra DM, Nagase H. Insulin-like growth factor binding protein (IGFBP) substrate zymography. A new tool to identify and characterize IGFBP-degrading proteinases. Endocrine. 7: 33-6. PMID 9449028 DOI: 10.1007/Bf02778059 |
0.536 |
|
| 1997 |
Mott JD, Khalifah RG, Nagase H, Shield CF, Hudson JK, Hudson BG. Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility Kidney International. 52: 1302-1312. PMID 9350653 DOI: 10.1038/Ki.1997.455 |
0.446 |
|
| 1997 |
Das SK, Yano S, Wang J, Edwards DR, Nagase H, Dey SK. Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in the mouse uterus during the peri-implantation period. Developmental Genetics. 21: 44-54. PMID 9291579 DOI: 10.1002/(Sici)1520-6408(1997)21:1<44::Aid-Dvg5>3.0.Co;2-8 |
0.542 |
|
| 1997 |
Gomis-Rüth FX, Maskos K, Betz M, Bergner A, Huber R, Suzuki K, Yoshida N, Nagase H, Brew K, Bourenkov GP, Bartunik H, Bode W. Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1. Nature. 389: 77-81. PMID 9288970 DOI: 10.1038/37995 |
0.771 |
|
| 1997 |
Huang W, Meng Q, Suzuki K, Nagase H, Brew K. Mutational study of the amino-terminal domain of human tissue inhibitor of metalloproteinases 1 (TIMP-1) locates an inhibitory region for matrix metalloproteinases Journal of Biological Chemistry. 272: 22086-22091. PMID 9268350 DOI: 10.1074/Jbc.272.35.22086 |
0.733 |
|
| 1997 |
Nagase H, Suzuki K, Cawston TE, Brew K. Involvement of a region near valine-69 of tissue inhibitor of metalloproteinases (TIMP)-1 in the interaction with matrix metalloproteinase 3 (stromelysin 1) Biochemical Journal. 325: 163-167. PMID 9224642 DOI: 10.1042/Bj3250163 |
0.757 |
|
| 1997 |
Ginestra A, Monea S, Seghezzi G, Dolo V, Nagase H, Mignatti P, Vittorelli ML. Urokinase plasminogen activator and gelatinases are associated with membrane vesicles shed by human HT1080 fibrosarcoma cells. The Journal of Biological Chemistry. 272: 17216-22. PMID 9202045 DOI: 10.1074/jbc.272.27.17216 |
0.386 |
|
| 1997 |
Imada K, Ito A, Sato T, Namiki M, Nagase H, Mori Y. Hormonal regulation of matrix metalloproteinase 9/gelatinase B gene expression in rabbit uterine cervical fibroblasts. Biology of Reproduction. 56: 575-80. PMID 9046999 DOI: 10.1095/Biolreprod56.3.575 |
0.433 |
|
| 1997 |
Korzus E, Nagase H, Rydell R, Travis J. The mitogen-activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element-mediated activation of matrix metalloproteinase 1 gene expression. The Journal of Biological Chemistry. 272: 1188-96. PMID 8995420 DOI: 10.1074/Jbc.272.2.1188 |
0.584 |
|
| 1996 |
Anderson SS, Wu K, Nagase H, Stettler-Stevenson WG, Kim Y, Tsilibary EC. Effect of matrix glycation on expression of type IV collagen, MMP-2, MMP-9 and TIMP-1 by human mesangial cells. Cell Adhesion and Communication. 4: 89-101. PMID 8937745 DOI: 10.3109/15419069609010765 |
0.574 |
|
| 1996 |
Hosono T, Ito A, Sato T, Nagase H, Mori Y. Translational Augmentation of Pro-matrix Metalloproteinase 3 (Prostromelysin 1) and a Tissue Inhibitor of Metalloproteinases (TIMP)-1 mRNAs by Epidermal Growth Factor and Transforming Growth Factor α, but not by Interleukin 1α or 12-O-Tetradecanoylphorbol 13-Acetate in Human Uterine Cervical Fibroblasts : The Possible Involvement of an Atypical Protein Kinase C Biological & Pharmaceutical Bulletin. 19: 1285-1290. PMID 8913498 DOI: 10.1248/Bpb.19.1285 |
0.384 |
|
| 1996 |
Rankin CA, Suzuki K, Itoh Y, Ziemer DM, Grantham JJ, Calvet JP, Nagase H. Matrix metalloproteinases and TIMPS in cultured C57BL/6J-cpk kidney tubules Kidney International. 50: 835-844. PMID 8872958 DOI: 10.1038/Ki.1996.383 |
0.572 |
|
| 1996 |
Nagase H, Suzuki K, Itoh Y, Kan CC, Gehring MR, Huang W, Brew K. Involvement of tissue inhibitors of metalloproteinases (TIMPs) during matrix metalloproteinase activation Advances in Experimental Medicine and Biology. 389: 23-31. PMID 8860990 DOI: 10.1007/978-1-4613-0335-0_3 |
0.717 |
|
| 1996 |
Bini A, Itoh Y, Kudryk BJ, Nagase H. Degradation of cross-linked fibrin by matrix metalloproteinase 3 (stromelysin 1): hydrolysis of the gamma Gly 404-Ala 405 peptide bond. Biochemistry. 35: 13056-63. PMID 8855941 DOI: 10.1021/Bi960730C |
0.602 |
|
| 1996 |
Fowlkes JL, Thrailkill KM, Serra DM, Suzuki K, Nagase H. Matrix metalloproteinases as insulin-like growth factor binding protein-degrading proteinases. Progress in Growth Factor Research. 6: 255-63. PMID 8817668 DOI: 10.1016/0955-2235(95)00017-8 |
0.597 |
|
| 1996 |
Stack MS, Itoh Y, Young TN, Nagase H. Fluorescence quenching studies of matrix metalloproteinases (MMPs): evidence for structural rearrangement of the proMMP-2/TIMP-2 complex upon mercurial activation. Archives of Biochemistry and Biophysics. 333: 163-9. PMID 8806767 DOI: 10.1006/Abbi.1996.0377 |
0.603 |
|
| 1996 |
Sharma R, Suzuki K, Nagase H, Savin VJ. Matrix metalloproteinase (stromelysin-1) increases the albumin permeability of isolated rat glomeruli Journal of Laboratory and Clinical Medicine. 128: 297-303. PMID 8783637 DOI: 10.1016/S0022-2143(96)90031-1 |
0.522 |
|
| 1996 |
Nagase H, Fields GB. Human matrix metalloproteinase specificity studies using collagen sequence-based synthetic peptides Biopolymers. 40: 399-416. PMID 8765610 DOI: 10.1002/(Sici)1097-0282(1996)40:4<399::Aid-Bip5>3.0.Co;2-R |
0.61 |
|
| 1996 |
Black RA, Durie FH, Otten-Evans C, Miller R, Slack JL, Lynch DH, Castner B, Mohler KM, Gerhart M, Johnson RS, Itoh Y, Okada Y, Nagase H. Relaxed specificity of matrix metalloproteinases (MMPS) and TIMP insensitivity of tumor necrosis factor-alpha (TNF-alpha) production suggest the major TNF-alpha converting enzyme is not an MMP. Biochemical and Biophysical Research Communications. 225: 400-405. PMID 8753775 DOI: 10.1006/Bbrc.1996.1186 |
0.529 |
|
| 1996 |
Jeziorska M, Nagase H, Salamonsen LA, Woolley DE. Immunolocalization of the matrix metalloproteinases gelatinase B and stromelysin 1 in human endometrium throughout the menstrual cycle. Reproduction. 107: 43-51. PMID 8699433 DOI: 10.1530/Jrf.0.1070043 |
0.379 |
|
| 1996 |
Ito A, Mukaiyama A, Itoh Y, Nagase H, Thogersen IB, Enghild JJ, Sasaguri Y, Mori Y. Degradation of interleukin 1beta by matrix metalloproteinases. The Journal of Biological Chemistry. 271: 14657-60. PMID 8663297 DOI: 10.1074/Jbc.271.25.14657 |
0.536 |
|
| 1996 |
Hosono T, Ito A, Sato T, Nagase H, Mori Y. Translational augmentation of pro-matrix metalloproteinase 3 (prostromelysin 1) and tissue inhibitor of metalloproteinases (TIMP)-1 mRNAs induced by epidermal growth factor in human uterine cervical fibroblasts. Febs Letters. 381: 115-8. PMID 8641416 DOI: 10.1016/0014-5793(96)00081-6 |
0.469 |
|
| 1996 |
Benbow U, Butticè G, Nagase H, Kurkinen M. Characterization of the 46-kDa intermediates of matrix metalloproteinase 3 (stromelysin 1) obtained by site-directed mutation of phenylalanine 83. The Journal of Biological Chemistry. 271: 10715-22. PMID 8631880 DOI: 10.1074/Jbc.271.18.10715 |
0.611 |
|
| 1996 |
Huang W, Suzuki K, Nagase H, Arumugam S, Van Doren SR, Brew K. Folding and characterization of the amino-terminal domain of human tissue inhibitor of metalloproteinases-1 (TIMP-1) expressed at high yield in E. coli Febs Letters. 384: 155-161. PMID 8612814 DOI: 10.1016/0014-5793(96)00304-3 |
0.65 |
|
| 1995 |
Suzuki K, Lees M, Newlands GF, Nagase H, Woolley DE. Activation of precursors for matrix metalloproteinases 1 (interstitial collagenase) and 3 (stromelysin) by rat mast-cell proteinases I and II. The Biochemical Journal. 301-6. PMID 7826345 DOI: 10.1042/Bj3050301 |
0.578 |
|
| 1995 |
Itoh Y, Binner S, Nagase H. Steps involved in activation of the complex of pro-matrix metalloproteinase 2 (progelatinase A) and tissue inhibitor of metalloproteinases (TIMP)-2 by 4-aminophenylmercuric acetate Biochemical Journal. 308: 645-651. PMID 7772054 DOI: 10.1042/Bj3080645 |
0.602 |
|
| 1995 |
Ito A, Nakajima S, Sasaguri Y, Nagase H, Mori Y. Co-culture of human breast adenocarcinoma MCF-7 cells and human dermal fibroblasts enhances the production of matrix metalloproteinases 1, 2 and 3 in fibroblasts. British Journal of Cancer. 71: 1039-45. PMID 7734296 DOI: 10.1038/bjc.1995.200 |
0.484 |
|
| 1995 |
Ogata Y, Itoh Y, Nagase H. Steps involved in activation of the pro-matrix metalloproteinase 9 (progelatinase B)-tissue inhibitor of metalloproteinases-1 complex by 4-aminophenylmercuric acetate and proteinases Journal of Biological Chemistry. 270: 18506-18511. PMID 7629179 DOI: 10.1074/Jbc.270.31.18506 |
0.615 |
|
| 1995 |
Itoh Y, Nagase H. Preferential inactivation of tissue inhibitor of metalloproteinase-1 that is bound to the precursor of matrix metalloproteinase 9 (progelatinase B) by human neutrophil elastase Journal of Biological Chemistry. 270: 16518-16521. PMID 7622455 DOI: 10.1074/Jbc.270.28.16518 |
0.64 |
|
| 1995 |
Abramson SR, Conner GE, Nagase H, Neuhaus I, Woessner JF. Characterization of rat uterine matrilysin and its cDNA. Relationship to human pump-1 and activation of procollagenases. The Journal of Biological Chemistry. 270: 16016-22. PMID 7608162 DOI: 10.1074/JBC.270.27.16016 |
0.349 |
|
| 1995 |
Thrailkill KM, Quarles LD, Nagase H, Suzuki K, Serra DM, Fowlkes JL. Characterization of insulin-like growth factor-binding protein 5-degrading proteases produced throughout murine osteoblast differentiation. Endocrinology. 136: 3527-33. PMID 7543045 DOI: 10.1210/ENDO.136.8.7543045 |
0.489 |
|
| 1995 |
Fowlkes JL, Suzuki K, Nagase H, Thrailkill KM. Proteolysis of insulin-like growth factor binding protein-3 during rat pregnancy: a role for matrix metalloproteinases. Endocrinology. 135: 2810-3. PMID 7527335 DOI: 10.1210/ENDO.135.6.7527335 |
0.464 |
|
| 1995 |
Springman EB, Nagase H, Birkedal-Hansen H, Van Wart HE. Zinc content and function in human fibroblast collagenase. Biochemistry. 34: 15713-20. PMID 7495802 DOI: 10.1021/Bi00048A016 |
0.439 |
|
| 1994 |
Takahashi S, Sato T, Ito A, Ojima Y, Hosono T, Nagase H, Mori Y. Involvement of protein kinase C in the interleukin 1 alpha-induced gene expression of matrix metalloproteinases and tissue inhibitor-1 of metalloproteinases (TIMP-1) in human uterine cervical fibroblasts. Biochimica Et Biophysica Acta. 1220: 57-65. PMID 8268245 DOI: 10.1016/0167-4889(93)90097-9 |
0.362 |
|
| 1994 |
Imada K, Ito A, Itoh Y, Nagase H, Mori Y. Progesterone increases the production of tissue inhibitor of metalloproteinases-2 in rabbit uterine cervical fibroblasts. Febs Letters. 341: 109-12. PMID 8137908 DOI: 10.1016/0014-5793(94)80250-5 |
0.476 |
|
| 1994 |
Jeziorska M, Haboubi NY, Schofield PF, Ogata Y, Nagase H, Woolley DE. Distribution of gelatinase B (MMP-9) and type IV collagen in colorectal carcinoma. International Journal of Colorectal Disease. 9: 141-148. PMID 7814988 DOI: 10.1007/Bf00290191 |
0.574 |
|
| 1994 |
Salamonsen LA, Hampton AL, Suzuki R, Nagase H. Modulation of production of matrix metalloproteinases from ovine endometrial cells by ovine trophoblast interferon. Journal of Reproduction and Fertility. 102: 155-62. PMID 7799308 DOI: 10.1530/Jrf.0.1020155 |
0.474 |
|
| 1994 |
Nagase H, Itoh Y, Binner S. Interaction of α2-macroglobulin with matrix metalloproteinases and its use for identification of their active forms Annals of the New York Academy of Sciences. 732: 294-302. PMID 7526760 DOI: 10.1111/J.1749-6632.1994.Tb24744.X |
0.455 |
|
| 1994 |
Newman KM, Jean-Claude J, Li H, Scholes JV, Ogata Y, Nagase H, Tilson MD. Cellular localization of matrix metalloproteinases in the abdominal aortic aneurysm wall. Journal of Vascular Surgery. 20: 814-20. PMID 7526009 DOI: 10.1016/S0741-5214(94)70169-5 |
0.6 |
|
| 1993 |
Salamonsen LA, Nagase H, Suzuki R, Woolley DE. Production of matrix metalloproteinase 1 (interstitial collagenase) and matrix metalloproteinase 2 (gelatinase A: 72 kDa gelatinase) by ovine endometrial cells in vitro: different regulation and preferential expression by stromal fibroblasts Reproduction. 98: 583-589. PMID 8410828 DOI: 10.1530/Jrf.0.0980583 |
0.625 |
|
| 1993 |
Chen LC, Noelken ME, Nagase H. Disruption of the cysteine-75 and zinc ion coordination is not sufficient to activate the precursor of human matrix metalloproteinase 3 (stromelysin 1) Biochemistry. 32: 10289-10295. PMID 8399171 DOI: 10.1021/Bi00090A003 |
0.453 |
|
| 1993 |
Tetlow LC, Lees M, Ogata Y, Nagase H, Woolley DE. Differential expression of gelatinase B (MMP-9) and stromelysin-1 (MMP-3) by rheumatoid synovial cells in vitro and in vivo. Rheumatology International. 13: 53-9. PMID 8356391 DOI: 10.1007/Bf00307734 |
0.617 |
|
| 1992 |
Yanagi H, Sasaguri Y, Sugama K, Morimatsu M, Nagase H. Production of tissue collagenase (matrix metalloproteinase 1) by human aortic smooth muscle cells in response to platelet-derived growth factor. Atherosclerosis. 91: 207-16. PMID 1665062 DOI: 10.1016/0021-9150(91)90168-3 |
0.456 |
|
| 1992 |
Ito A, Itoh Y, Sato T, Mori Y, Suzuki K, Nagase H. Identification of rabbit uterine cervical procollagenase activator as rabbit matrix metalloproteinase 3 (stromelysin). Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 99: 381-5. PMID 1662594 DOI: 10.1016/0305-0491(91)90058-L |
0.388 |
|
| 1992 |
Morodomi T, Ogata Y, Sasaguri Y, Morimatsu M, Nagase H. Purification and characterization of matrix metalloproteinase 9 from U937 monocytic leukaemia and HT1080 fibrosarcoma cells. The Biochemical Journal. 603-11. PMID 1379048 DOI: 10.1042/Bj2850603 |
0.566 |
|
| 1992 |
Ogata Y, Pratta MA, Nagase H, Arner EC. Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) is induced in rabbit articular chondrocytes by cotreatment with interleukin 1 beta and a protein kinase C activator. Experimental Cell Research. 201: 245-9. PMID 1322311 DOI: 10.1016/0014-4827(92)90271-9 |
0.386 |
|
| 1991 |
Suzuki K, Enghild JJ, Morodomi T, Salvesen G, Nagase H. Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin). Biochemistry. 29: 10261-70. PMID 2176865 DOI: 10.1021/Bi00496A016 |
0.562 |
|
| 1991 |
Netzel-Arnett S, Mallya SK, Nagase H, Birkedal-Hansen H, Van Wart HE. Continuously recording fluorescent assays optimized for five human matrix metalloproteinases. Analytical Biochemistry. 195: 86-92. PMID 1888020 DOI: 10.1016/0003-2697(91)90299-9 |
0.464 |
|
| 1991 |
Ito A, Kakizaki M, Nagase H, Murakami S, Yamada H, Mori Y. Effects of H2-receptor antagonists on matrix metalloproteinases in rat gastric tissues with acetic acid-induced ulcer. Journal of Pharmacobio-Dynamics. 14: 285-291. PMID 1686058 DOI: 10.1248/Bpb1978.14.285 |
0.369 |
|
| 1991 |
Sato T, Ito A, Mori Y, Yamashita K, Hayakawa T, Nagase H. Hormonal regulation of collagenolysis in uterine cervical fibroblasts. Modulation of synthesis of procollagenase, prostromelysin and tissue inhibitor of metalloproteinases (TIMP) by progesterone and oestradiol-17 beta. The Biochemical Journal. 645-50. PMID 1645518 DOI: 10.1042/Bj2750645 |
0.529 |
|
| 1990 |
Nagase H. Step wise activation mechanisms of the precursor of matrix metalloproteinase 3 (Stromelysin) by proteinases and (4-Aminophenyl)mercuric Acetate Biochemistry®. 29: 5783-5789. PMID 2383557 DOI: 10.1021/Bi00476A020 |
0.546 |
|
| 1990 |
Okada Y, Morodomi T, Enghild JJ, Suzuki K, Yasui A, Nakanishi I, Salvesen G, Nagase H. Matrix metalloproteinase 2 from human rheumatoid synovial fibroblasts. Purification and activation of the precursor and enzymic properties. European Journal of Biochemistry / Febs. 194: 721-30. PMID 2269296 DOI: 10.1111/J.1432-1033.1990.Tb19462.X |
0.643 |
|
| 1990 |
Okada Y, Gonoji Y, Nakanishi I, Nagase H, Hayakawa T. Immunohistochemical demonstration of collagenase and tissue inhibitor of metalloproteinases (TIMP) in synovial lining cells of rheumatoid synovium. Virchows Archiv. B, Cell Pathology Including Molecular Pathology. 59: 305-12. PMID 1980561 DOI: 10.1007/Bf02899418 |
0.465 |
|
| 1989 |
Bejarano PA, Noelken ME, Suzuki K, Hudson BG, Nagase H. Degradation of basement membranes by human matrix metalloproteinase 3 (stromelysin). The Biochemical Journal. 256: 413-9. PMID 3223920 DOI: 10.1042/Bj2560413 |
0.571 |
|
| 1989 |
Gunja-Smith Z, Nagase H, Woessner JF. Purification of the neutral proteoglycan-degrading metalloproteinase from human articular cartilage tissue and its identification as stromelysin matrix metalloproteinase-3. The Biochemical Journal. 258: 115-9. PMID 2930500 DOI: 10.1042/Bj2580115 |
0.505 |
|
| 1989 |
Okada Y, Konomi H, Yada T, Kimata K, Nagase H. Degradation of type IX collagen by matrix metalloproteinase 3 (stromelysin) from human rheumatoid synovial cells. Febs Letters. 244: 473-6. PMID 2920840 DOI: 10.1016/0014-5793(89)80586-1 |
0.601 |
|
| 1989 |
Okada Y, Takeuchi N, Tomita K, Nakanishi I, Nagase H. Immunolocalization of matrix metalloproteinase 3 (stromelysin) in rheumatoid synovioblasts (B cells): correlation with rheumatoid arthritis. Annals of the Rheumatic Diseases. 48: 645-53. PMID 2675782 DOI: 10.1136/Ard.48.8.645 |
0.555 |
|
| 1988 |
Okada Y, Watanabe S, Nakanishi I, Kishi J, Hayakawa T, Watorek W, Travis J, Nagase H. Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinases. Febs Letters. 229: 157-60. PMID 3162216 DOI: 10.1016/0014-5793(88)80817-2 |
0.594 |
|
| 1988 |
Murphy G, Nagase H, Brinckerhoff CE. Relationship of procollagenase activator, stromelysin and matrix metalloproteinase 3 Collagen and Related Research. 8: 389-391. PMID 2850888 DOI: 10.1016/S0174-173X(88)80009-8 |
0.538 |
|
| 1988 |
Ito A, Nagase H. Evidence that human rheumatoid synovial matrix metalloproteinase 3 is an endogenous activator of procollagenase Archives of Biochemistry and Biophysics. 267: 211-216. PMID 2848449 DOI: 10.1016/0003-9861(88)90025-2 |
0.612 |
|
| 1988 |
Spinucci C, Zucker S, Wieman JM, Lysik RM, Imhof B, Ramamurthy N, Liotta LA, Nagase H. Purification of a gelatin-degrading type IV collagenase secreted by ras oncogene-transformed fibroblasts. Journal of the National Cancer Institute. 80: 1416-20. PMID 2845110 DOI: 10.1093/Jnci/80.17.1416 |
0.398 |
|
| 1988 |
Ito A, Goshowaki H, Sato T, Mori Y, Yamashita K, Hayakawa T, Nagase H. Human recombinant interleukin-1 alpha-mediated stimulation of procollagenase production and suppression of biosynthesis of tissue inhibitor of metalloproteinases in rabbit uterine cervical fibroblasts. Febs Letters. 234: 326-30. PMID 2839371 DOI: 10.1016/0014-5793(88)80109-1 |
0.374 |
|
| 1987 |
Nagase H, Brew K. Amino acid sequence of a 32-residue region around the thiol ester site in duck ovostatin Febs Letters. 222: 83-88. PMID 3653403 DOI: 10.1016/0014-5793(87)80196-5 |
0.521 |
|
| 1982 |
Nagase H, Cawston TE, De Silva M, Barrett AJ. Identification of plasma kallikrein as an activator of latent collagenase in rheumatoid synovial fluid. Biochimica Et Biophysica Acta. 702: 133-42. PMID 6279161 DOI: 10.1016/0167-4838(82)90036-X |
0.356 |
|
| 1980 |
Nagase H, Woessner JF. An improved assay for proteases and polysaccharidases employing a cartilage proteoglycan substrate entrapped in polyacrylamide particles Analytical Biochemistry. 107: 385-392. PMID 7001953 DOI: 10.1016/0003-2697(80)90400-5 |
0.327 |
|
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