| Year |
Citation |
Score |
| 2020 |
Moran SP, Conn PJ. Leveraging bias to your advantage. Nature Chemical Biology. 16: 226-227. PMID 32080631 DOI: 10.1038/S41589-020-0468-2 |
0.34 |
|
| 2019 |
Moran SP, Xiang Z, Doyle CA, Maksymetz J, Lv X, Faltin S, Fisher NM, Niswender CM, Rook JM, Lindsley CW, Conn PJ. Biased M receptor-positive allosteric modulators reveal role of phospholipase D in M-dependent rodent cortical plasticity. Science Signaling. 12. PMID 31796631 DOI: 10.1126/Scisignal.Aax2057 |
0.4 |
|
| 2019 |
Moran SP, Maksymetz J, Conn PJ. Targeting Muscarinic Acetylcholine Receptors for the Treatment of Psychiatric and Neurological Disorders. Trends in Pharmacological Sciences. 40: 1006-1020. PMID 31711626 DOI: 10.1016/J.Tips.2019.10.007 |
0.379 |
|
| 2018 |
Rook JM, Bertron JL, Cho HP, Garcia-Barrantes PM, Moran SP, Maksymetz JT, Nance KD, Dickerson JW, Remke DH, Chang S, Harp J, Blobaum AL, Niswender CM, Jones CK, Stauffer SR, et al. A novel M1 PAM VU0486846 exerts efficacy in cognition models without displaying agonist activity or cholinergic toxicity. Acs Chemical Neuroscience. PMID 29701957 DOI: 10.1021/Acschemneuro.8B00131 |
0.434 |
|
| 2018 |
Moran SP, Cho HP, Maksymetz J, Remke DH, Hanson RM, Niswender CM, Lindsley CW, Rook JM, Conn PJ. PF-06827443 displays robust allosteric agonist and positive allosteric modulator activity in high receptor reserve and native systems. Acs Chemical Neuroscience. PMID 29683646 DOI: 10.1021/Acschemneuro.8B00106 |
0.429 |
|
| 2018 |
Moran SP, Dickerson JW, Cho HP, Xiang Z, Maksymetz J, Remke DH, Lv X, Doyle CA, Rajan DH, Niswender CM, Engers DW, Lindsley CW, Rook JM, Conn PJ. M-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29581537 DOI: 10.1038/S41386-018-0033-9 |
0.409 |
|
| 2017 |
Ghoshal A, Moran SP, Dickerson JW, Joffe ME, Grueter BA, Xiang Z, Lindsley CW, Rook JM, Conn PJ. Role of mGlu5 receptors and inhibitory neurotransmission in M1 dependent muscarinic LTD in the prefrontal cortex: implications in schizophrenia. Acs Chemical Neuroscience. PMID 28679049 DOI: 10.1021/Acschemneuro.7B00167 |
0.429 |
|
| 2017 |
Maksymetz J, Moran SP, Conn PJ. Targeting metabotropic glutamate receptors for novel treatments of schizophrenia. Molecular Brain. 10: 15. PMID 28446243 DOI: 10.1186/S13041-017-0293-Z |
0.402 |
|
| 2016 |
Grannan MD, Mielnik CA, Moran S, Gould RW, Ball JR, Lu Z, Bubser M, Ramsey AJ, Abe M, Cho HP, Nance KD, Blobaum AL, Niswender CM, Conn PJ, Lindsley CW, et al. Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction are Reversed by the Novel M1 PAM VU6004256. Acs Chemical Neuroscience. PMID 27617634 DOI: 10.1021/Acschemneuro.6B00230 |
0.442 |
|
| 2016 |
Raper J, Bosinger S, Johnson Z, Tharp G, Moran S, Chan AW. Increased irritability, anxiety, and immune reactivity in transgenic Huntington's disease monkeys. Brain, Behavior, and Immunity. PMID 27395434 DOI: 10.1016/J.Bbi.2016.07.004 |
0.346 |
|
| 2015 |
Chan AW, Jiang J, Chen Y, Li C, Prucha MS, Hu Y, Chi T, Moran S, Rahim T, Li S, Li X, Zola SM, Testa CM, Mao H, Villalba R, et al. Progressive cognitive deficit, motor impairment and striatal pathology in a transgenic Huntington disease monkey model from infancy to adulthood. Plos One. 10: e0122335. PMID 25966278 DOI: 10.1371/Journal.Pone.0122335 |
0.384 |
|
| 2015 |
Moran S, Chi T, Prucha MS, Ahn KS, Connor-Stroud F, Jean S, Gould K, Chan AW. Germline transmission in transgenic Huntington's disease monkeys. Theriogenology. 84: 277-85. PMID 25917881 DOI: 10.1016/J.Theriogenology.2015.03.016 |
0.339 |
|
| 2014 |
Carter RL, Chen Y, Kunkanjanawan T, Xu Y, Moran SP, Putkhao K, Yang J, Huang AH, Parnpai R, Chan AW. Reversal of cellular phenotypes in neural cells derived from Huntington's disease monkey-induced pluripotent stem cells. Stem Cell Reports. 3: 585-93. PMID 25358787 DOI: 10.1016/J.Stemcr.2014.07.011 |
0.345 |
|
| 2014 |
Chan AW, Xu Y, Jiang J, Rahim T, Zhao D, Kocerha J, Chi T, Moran S, Engelhardt H, Larkin K, Neumann A, Cheng H, Li C, Nelson K, Banta H, et al. A two years longitudinal study of a transgenic Huntington disease monkey. Bmc Neuroscience. 15: 36. PMID 24581271 DOI: 10.1186/1471-2202-15-36 |
0.358 |
|
| 2013 |
Kocerha J, Liu Y, Willoughby D, Chidamparam K, Benito J, Nelson K, Xu Y, Chi T, Engelhardt H, Moran S, Yang SH, Li SH, Li XJ, Larkin K, Neumann A, et al. Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington's disease monkeys. Bmc Neuroscience. 14: 88. PMID 23957861 DOI: 10.1186/1471-2202-14-88 |
0.378 |
|
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