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Thorsten Fritzius - Publications

Affiliations: 
Biomedicine University of Basel, Basel, Basel-Stadt, Switzerland 
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Trovò L, Kouvaros S, Schwenk J, Fernandez-Fernandez D, Fritzius T, Rem PD, Früh S, Gassmann M, Fakler B, Bischofberger J, Bettler B. Synaptotagmin-11 facilitates assembly of a presynaptic signaling complex in post-Golgi cargo vesicles. Embo Reports. PMID 38698221 DOI: 10.1038/s44319-024-00147-0  0.816
2024 Fritzius T, Tureček R, Fernandez-Fernandez D, Isogai S, Rem PD, Kralikova M, Gassmann M, Bettler B. Preassembly of specific Gβγ subunits at GABA receptors through auxiliary KCTD proteins accelerates channel gating. Biochemical Pharmacology. 116176. PMID 38555036 DOI: 10.1016/j.bcp.2024.116176  0.85
2023 Rem PD, Sereikaite V, Fernández-Fernández D, Reinartz S, Ulrich D, Fritzius T, Trovo L, Roux S, Chen Z, Rondard P, Pin JP, Schwenk J, Fakler B, Gassmann M, Barkat TR, et al. Soluble amyloid-β precursor peptide does not regulate GABA receptor activity. Elife. 12. PMID 36688536 DOI: 10.7554/eLife.82082  0.778
2021 Bhandari P, Vandael D, Fernández-Fernández D, Fritzius T, Kleindienst D, Önal C, Montanaro J, Gassmann M, Jonas P, Kulik A, Bettler B, Shigemoto R, Koppensteiner P. GABA receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminals. Elife. 10. PMID 33913808 DOI: 10.7554/eLife.68274  0.83
2020 Werthmann RC, Tzouros M, Lamerz J, Augustin A, Fritzius T, Trovo L, Stawarski M, Raveh A, Diener C, Fischer C, Gassmann M, Lindemann L, Bettler B. Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors. Neuropharmacology. 108426. PMID 33279506 DOI: 10.1016/j.neuropharm.2020.108426  0.772
2020 Fritzius T, Stawarski M, Isogai S, Bettler B. Structural Basis of GABA Receptor Regulation and Signaling. Current Topics in Behavioral Neurosciences. PMID 32812202 DOI: 10.1007/7854_2020_147  0.863
2019 Sereikaite V, Fritzius T, Kasaragod V, Bader N, Maric H, Schindelin H, Bettler B, Strømgaard K. Targeting the γ-aminobutyric acid type B (GABAB) receptor complex: Development of inhibitors targeting the K+ channel tetramerization domain (KCTD) containing proteins/GABAB receptor protein-protein interaction. Journal of Medicinal Chemistry. PMID 31509708 DOI: 10.1021/Acs.Jmedchem.9B01087  0.719
2019 Fritzius T, Bettler B. The organizing principle of GABA receptor complexes: Physiological and pharmacological implications. Basic & Clinical Pharmacology & Toxicology. PMID 31033219 DOI: 10.1111/Bcpt.13241  0.758
2019 Dinamarca MC, Raveh A, Schneider A, Fritzius T, Früh S, Rem PD, Stawarski M, Lalanne T, Turecek R, Choo M, Besseyrias V, Bildl W, Bentrop D, Staufenbiel M, Gassmann M, et al. Complex formation of APP with GABA receptors links axonal trafficking to amyloidogenic processing. Nature Communications. 10: 1331. PMID 30902970 DOI: 10.1038/S41467-019-09164-3  0.692
2016 Fritzius T, Turecek R, Seddik R, Kobayashi H, Tiao J, Rem PD, Metz M, Kralikova M, Bouvier M, Gassmann M, Bettler B. KCTD hetero-oligomers confer unique kinetic properties on hippocampal GABAB receptor-induced K+-currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28003345 DOI: 10.1523/Jneurosci.2181-16.2016  0.81
2015 Schwenk J, Pérez-Garci E, Schneider A, Kollewe A, Gauthier-Kemper A, Fritzius T, Raveh A, Dinamarca MC, Hanuschkin A, Bildl W, Klingauf J, Gassmann M, Schulte U, Bettler B, Fakler B. Modular composition and dynamics of native GABAB receptors identified by high-resolution proteomics. Nature Neuroscience. PMID 26691831 DOI: 10.1038/Nn.4198  0.812
2015 Rajalu M, Fritzius T, Adelfinger L, Jacquier V, Besseyrias V, Gassmann M, Bettler B. Pharmacological characterization of GABAB receptor subtypes assembled with auxiliary KCTD subunits. Neuropharmacology. 88: 145-54. PMID 25196734 DOI: 10.1016/J.Neuropharm.2014.08.020  0.836
2014 Turecek R, Schwenk J, Fritzius T, Ivankova K, Zolles G, Adelfinger L, Jacquier V, Besseyrias V, Gassmann M, Schulte U, Fakler B, Bettler B. Auxiliary GABAB receptor subunits uncouple G protein βγ subunits from effector channels to induce desensitization. Neuron. 82: 1032-44. PMID 24836506 DOI: 10.1016/J.Neuron.2014.04.015  0.823
2013 Ivankova K, Turecek R, Fritzius T, Seddik R, Prezeau L, Comps-Agrar L, Pin JP, Fakler B, Besseyrias V, Gassmann M, Bettler B. Up-regulation of GABA(B) receptor signaling by constitutive assembly with the K+ channel tetramerization domain-containing protein 12 (KCTD12). The Journal of Biological Chemistry. 288: 24848-56. PMID 23843457 DOI: 10.1074/Jbc.M113.476770  0.854
2013 Dill MT, Tornillo L, Fritzius T, Terracciano L, Semela D, Bettler B, Heim MH, Tchorz JS. Constitutive Notch2 signaling induces hepatic tumors in mice. Hepatology (Baltimore, Md.). 57: 1607-19. PMID 23175466 DOI: 10.1002/Hep.26165  0.716
2012 Seddik R, Jungblut SP, Silander OK, Rajalu M, Fritzius T, Besseyrias V, Jacquier V, Fakler B, Gassmann M, Bettler B. Opposite effects of KCTD subunit domains on GABA(B) receptor-mediated desensitization. The Journal of Biological Chemistry. 287: 39869-77. PMID 23035119 DOI: 10.1074/Jbc.M112.412767  0.809
2010 Schwenk J, Metz M, Zolles G, Turecek R, Fritzius T, Bildl W, Tarusawa E, Kulik A, Unger A, Ivankova K, Seddik R, Tiao JY, Rajalu M, Trojanova J, Rohde V, et al. Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits. Nature. 465: 231-5. PMID 20400944 DOI: 10.1038/Nature08964  0.793
2009 Baumgartner M, Weiss A, Fritzius T, Heinrich J, Moelling K. The PDZ protein MPP2 interacts with c-Src in epithelial cells. Experimental Cell Research. 315: 2888-98. PMID 19665017 DOI: 10.1016/J.Yexcr.2009.07.028  0.316
2008 Fritzius T, Moelling K. Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis. The Embo Journal. 27: 1399-410. PMID 18388859 DOI: 10.1038/Emboj.2008.67  0.311
2007 Fritzius T, Frey AD, Schweneker M, Mayer D, Moelling K. WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta. The Febs Journal. 274: 1552-66. PMID 17313651 DOI: 10.1111/J.1742-4658.2007.05702.X  0.382
2006 Fritzius T, Burkard G, Haas E, Heinrich J, Schweneker M, Bosse M, Zimmermann S, Frey AD, Caelers A, Bachmann AS, Moelling K. A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda. The Biochemical Journal. 399: 9-20. PMID 16792529 DOI: 10.1042/Bj20060511  0.387
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