| Year |
Citation |
Score |
| 2018 |
Juncosa JI, Takaya K, Le HV, Moschitto MJ, Weerawarna PM, Mascarenhas R, Liu D, Dewey SL, Silverman RB. Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction. Journal of the American Chemical Society. PMID 29381352 DOI: 10.1021/Jacs.7B10965 |
0.695 |
|
| 2017 |
Wu R, Sanishvili R, Belitsky BR, Juncosa JI, Le HV, Lehrer HJ, Farley M, Silverman RB, Petsko GA, Ringe D, Liu D. PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28348215 DOI: 10.1073/Pnas.1703019114 |
0.656 |
|
| 2015 |
Lee H, Doud EH, Wu R, Sanishvili R, Juncosa JI, Liu D, Kelleher NL, Silverman RB. Mechanism of inactivation of γ-aminobutyric acid aminotransferase by (1S,3S)-3-amino-4-difluoromethylene-1-cyclopentanoic acid (CPP-115). Journal of the American Chemical Society. 137: 2628-40. PMID 25616005 DOI: 10.1021/Ja512299N |
0.548 |
|
| 2015 |
Lee H, Juncosa JI, Silverman RB. Ornithine aminotransferase versus GABA aminotransferase: implications for the design of new anticancer drugs. Medicinal Research Reviews. 35: 286-305. PMID 25145640 DOI: 10.1002/Med.21328 |
0.549 |
|
| 2013 |
Juncosa JI, Lee H, Silverman RB. Two continuous coupled assays for ornithine-δ-aminotransferase Analytical Biochemistry. 440: 145-149. PMID 23747282 DOI: 10.1016/J.Ab.2013.05.025 |
0.442 |
|
| 2013 |
Juncosa JI, Hansen M, Bonner LA, Cueva JP, Maglathlin R, McCorvy JD, Marona-Lewicka D, Lill MA, Nichols DE. Extensive rigid analogue design maps the binding conformation of potent N-benzylphenethylamine 5-HT2A serotonin receptor agonist ligands. Acs Chemical Neuroscience. 4: 96-109. PMID 23336049 DOI: 10.1021/Cn3000668 |
0.724 |
|
| 2013 |
Juncosa JI, Groves AP, Xia G, Silverman RB. Probing the steric requirements of the γ-aminobutyric acid aminotransferase active site with fluorinated analogues of vigabatrin. Bioorganic & Medicinal Chemistry. 21: 903-11. PMID 23306054 DOI: 10.1016/J.Bmc.2012.12.009 |
0.57 |
|
| 2012 |
Cueva JP, Chemel BR, Juncosa JI, Lill MA, Watts VJ, Nichols DE. Analogues of doxanthrine reveal differences between the dopamine D1 receptor binding properties of chromanoisoquinolines and hexahydrobenzo[a]phenanthridines. European Journal of Medicinal Chemistry. 48: 97-107. PMID 22204903 DOI: 10.1016/J.Ejmech.2011.11.039 |
0.713 |
|
| 2011 |
Cueva JP, Gallardo-Godoy A, Juncosa JI, Vidi PA, Lill MA, Watts VJ, Nichols DE. Probing the steric space at the floor of the D1 dopamine receptor orthosteric binding domain: 7α-, 7β-, 8α-, and 8β-methyl substituted dihydrexidine analogues. Journal of Medicinal Chemistry. 54: 5508-21. PMID 21714510 DOI: 10.1021/Jm200334C |
0.746 |
|
| 2011 |
Bonner LA, Laban U, Chemel BR, Juncosa JI, Lill MA, Watts VJ, Nichols DE. Mapping the catechol binding site in dopamine D₁ receptors: synthesis and evaluation of two parallel series of bicyclic dopamine analogues. Chemmedchem. 6: 1024-40. PMID 21538900 DOI: 10.1002/Cmdc.201100010 |
0.574 |
|
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