Year |
Citation |
Score |
2023 |
Terry AV, Jones K, Bertrand D. Nicotinic acetylcholine receptors in neurological and psychiatric diseases. Pharmacological Research. 106764. PMID 37044234 DOI: 10.1016/j.phrs.2023.106764 |
0.38 |
|
2023 |
Carlson EC, Macsai M, Bertrand S, Bertrand D, Nau J. The SARS-CoV-2 Virus and the Cholinergic System: Spike Protein Interaction with Human Nicotinic Acetylcholine Receptors and the Nicotinic Agonist Varenicline. International Journal of Molecular Sciences. 24. PMID 36982671 DOI: 10.3390/ijms24065597 |
0.411 |
|
2022 |
Nys M, Zarkadas E, Brams M, Mehregan A, Kambara K, Kool J, Casewell NR, Bertrand D, Baenziger JE, Nury H, Ulens C. The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors. Nature Communications. 13: 4543. PMID 35927270 DOI: 10.1038/s41467-022-32174-7 |
0.388 |
|
2021 |
Knoflach F, Bertrand D. Pharmacological modulation of GABA receptors. Current Opinion in Pharmacology. 59: 3-10. PMID 34020139 DOI: 10.1016/j.coph.2021.04.003 |
0.319 |
|
2020 |
Bertrand D, Wallace TL. A Review of the Cholinergic System and Therapeutic Approaches to Treat Brain Disorders. Current Topics in Behavioral Neurosciences. PMID 32451956 DOI: 10.1007/7854_2020_141 |
0.466 |
|
2020 |
Bertrand D. Neuronal Nicotinic Acetylcholine Receptors and Epilepsy. Epilepsy Currents. 2: 191-193. PMID 15309115 DOI: 10.1046/J.1535-7597.2002.00072.X |
0.448 |
|
2020 |
Brams M, Govaerts C, Kambara K, Price KL, Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SC, Hibbs RE, Steyaert J, Ulens C. Author response: Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site Elife. DOI: 10.7554/Elife.51511.Sa2 |
0.362 |
|
2020 |
Ulens C, Bisseling Q, Brams M, Mehregan A, Evans GL, Pasini D, Beard H, Verhelst S, Fish A, van Dorst S, Kambara K, Bertrand D. Molecular Recognition of Neonicotinoid Insecticides by Honeybee Nicotinic Receptors and ACHBP Homologues Biophysical Journal. 118: 585a. DOI: 10.1016/J.Bpj.2019.11.3171 |
0.503 |
|
2020 |
Baenziger JE, Henault CM, Govaerts C, Estrada A, Lynch J, Bertrand D, Pardon E, Evans G, Woods KN, Elberson BW, Cuello LG, Brannigan GH, Nury H, Steyaert J, Ulens C. A Lipid Recognition Site at a Transmembrane Helix Kink Shapes the Agonist Response of a Pentameric Ligand-gated Ion Channel Biophysical Journal. 118: 191a. DOI: 10.1016/J.Bpj.2019.11.1156 |
0.326 |
|
2019 |
Foo CS, Jobichen C, Hassan-Puttaswamy V, Dekan Z, Tae HS, Bertrand D, Adams DJ, Alewood PF, Sivaraman J, Nirthanan S, Kini RM. Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic acetylcholine receptors. British Journal of Pharmacology. PMID 31877243 DOI: 10.1111/Bph.14954 |
0.547 |
|
2019 |
Fernandes P, Pereira D, Watkins PB, Bertrand D. Differentiating the Pharmacodynamics and Toxicology of Macrolide and Ketolide Antibiotics. Journal of Medicinal Chemistry. PMID 31644280 DOI: 10.1021/Acs.Jmedchem.9B01159 |
0.323 |
|
2019 |
van Goethem NP, Paes D, Puzzo D, Fedele E, Rebosio C, Gulisano W, Palmeri A, Wennogle LP, Peng Y, Bertrand D, Prickaerts J. Antagonizing α7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition. Cellular Signalling. PMID 31176021 DOI: 10.1016/j.cellsig.2019.06.003 |
0.33 |
|
2019 |
Danober L, Kambara K, Bertrand S, Bertrand D, Benoist A, Fourquez J, Chollet A, Gloanec P, Jeggo R. P2-065: IN VITRO PHARMACOLOGICAL CHARACTERIZATION OF S68890, AN ALLOSTERIC MODULATOR OF ALPHA7 NICOTINIC RECEPTORS Alzheimer's & Dementia. 15: P595-P596. DOI: 10.1016/J.Jalz.2019.06.2472 |
0.513 |
|
2018 |
Knoflach F, Hernandez MC, Bertrand D. Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission. Journal of Visualized Experiments : Jove. PMID 30175997 DOI: 10.3791/57842 |
0.465 |
|
2018 |
Bertrand D, Terry AV. The wonderland of neuronal nicotinic acetylcholine receptors. Biochemical Pharmacology. 151: 214-225. PMID 29248596 DOI: 10.1016/J.Bcp.2017.12.008 |
0.447 |
|
2018 |
De Peuter H, Brams M, Joseph D, Bertrand D, Ulens C. Allosteric Modulation of the Pentameric Ligand-Gated Ion Channel ELIC by Barbiturates Biophysical Journal. 114: 300a. DOI: 10.1016/J.Bpj.2017.11.1709 |
0.305 |
|
2018 |
Brams M, De Peuter H, Spurny R, Pardon E, Bertrand D, Steyaert J, Govaerts C, Ulens C. Allosteric Modulation of the Pentameric Ligand-Gated Ion Channel ELIC by Functionally Active Nanobodies Biophysical Journal. 114: 298a. DOI: 10.1016/J.Bpj.2017.11.1700 |
0.314 |
|
2017 |
Bretin S, Louis C, Seguin L, Wagner S, Thomas JY, Challal S, Rogez N, Albinet K, Iop F, Villain N, Bertrand S, Krazem A, Bérachochéa D, Billiald S, Tordjman C, ... ... Bertrand D, et al. Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptors. Plos One. 12: e0184429. PMID 28886144 DOI: 10.1371/Journal.Pone.0184429 |
0.404 |
|
2017 |
Callahan PM, Bertrand D, Bertrand S, Plagenhoef MR, Terry AV. Tropisetron sensitizes α7 containing nicotinic receptors to low levels of acetylcholine in vitro and improves memory-related task performance in young and aged animals. Neuropharmacology. PMID 28259598 DOI: 10.1016/J.Neuropharm.2017.02.025 |
0.448 |
|
2016 |
Bertrand D, Biton B, Licher T, Chambard JM, Lanneau C, Partiseti M, Lefevre IA. Functional Studies of Sodium Channels: From Target to Compound Identification. Current Protocols in Pharmacology. 75: 9.21.1-9.21.35. PMID 27960031 DOI: 10.1002/Cpph.14 |
0.308 |
|
2016 |
Fernandes P, Martens E, Bertrand D, Pereira D. The solithromycin journey-It is all in the chemistry. Bioorganic & Medicinal Chemistry. PMID 27595539 DOI: 10.1016/J.Bmc.2016.08.035 |
0.392 |
|
2016 |
Lyukmanova EN, Shulepko MA, Shenkarev ZO, Bychkov ML, Paramonov AS, Chugunov AO, Kulbatskii DS, Arvaniti M, Dolejsi E, Schaer T, Arseniev AS, Efremov RG, Thomsen MS, Dolezal V, Bertrand D, et al. Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors. Scientific Reports. 6: 30698. PMID 27485575 DOI: 10.1038/srep30698 |
0.331 |
|
2016 |
Knoflach F, Hernandez MC, Bertrand D. GABAA receptor-mediated neurotransmission: Not so simple after all. Biochemical Pharmacology. PMID 27002180 DOI: 10.1016/J.Bcp.2016.03.014 |
0.458 |
|
2016 |
Wijckmans E, Nys M, Debaveye S, Brams M, Pardon E, Willegems K, Bertrand D, Steyaert J, Efremov R, Ulens C. Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues. Plos One. 11: e0151183. PMID 26999666 DOI: 10.1371/Journal.Pone.0151183 |
0.442 |
|
2016 |
Wijckmans E, Nys M, Debaveye S, Brams M, Pardon E, Willegems K, Bertrand D, Steyaert J, Efremov R, Ulens C. Functional and biochemical characterization of alvinella pompejana Cys-Loop receptor homologues Plos One. 11. DOI: 10.1371/journal.pone.0151183 |
0.326 |
|
2016 |
Bürgi JJ, Bertrand S, Marger F, Bertrand D, Reymond J. Fluorescent Agonists of the α
7 Nicotinic Acetylcholine Receptor Derived from 3-Amino-Quinuclidine Helvetica Chimica Acta. 99: 790-804. DOI: 10.1002/Hlca.201600120 |
0.463 |
|
2015 |
Wallace TL, Bertrand D. Neuronal α7 Nicotinic Receptors as a Target for the Treatment of Schizophrenia. International Review of Neurobiology. 124: 79-111. PMID 26472526 DOI: 10.1016/Bs.Irn.2015.08.003 |
0.328 |
|
2015 |
Bertrand D, Lee CH, Flood D, Marger F, Donnelly-Roberts D. Therapeutic Potential of α7 Nicotinic Acetylcholine Receptors. Pharmacological Reviews. 67: 1025-73. PMID 26419447 DOI: 10.1124/pr.113.008581 |
0.407 |
|
2015 |
Stoiljkovic M, Leventhal L, Chen A, Chen T, Driscoll R, Flood D, Hodgdon H, Hurst R, Nagy D, Piser T, Tang C, Townsend M, Tu Z, Bertrand D, Koenig G, et al. Concentration-response relationship of the α7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays. Biochemical Pharmacology. PMID 26206187 DOI: 10.1016/J.Bcp.2015.07.006 |
0.432 |
|
2015 |
Dani JA, Donnelly-Roberts D, Bertrand D. Nicotinic acetylcholine receptors as therapeutic targets: Emerging frontiers in basic research and clinical science - Editorial Comments. Biochemical Pharmacology. 97: 351. PMID 26074266 DOI: 10.1016/j.bcp.2015.06.004 |
0.331 |
|
2015 |
Eggert M, Winterer G, Wanischeck M, Hoda JC, Bertrand D, Steinlein O. The nicotinic acetylcholine receptor alpha 4 subunit contains a functionally relevant SNP Haplotype. Bmc Genetics. 16: 46. PMID 25934188 DOI: 10.1186/S12863-015-0204-1 |
0.438 |
|
2015 |
Spurny R, Debaveye S, Farinha A, Veys K, Vos AM, Gossas T, Atack J, Bertrand S, Bertrand D, Danielson UH, Tresadern G, Ulens C. Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 112: E2543-52. PMID 25918415 DOI: 10.1073/Pnas.1418289112 |
0.453 |
|
2015 |
Terry AV, Callahan PM, Bertrand D. R-(+) and S-(-) isomers of cotinine augment cholinergic responses in vitro and in vivo. The Journal of Pharmacology and Experimental Therapeutics. 352: 405-18. PMID 25503389 DOI: 10.1124/Jpet.114.219881 |
0.409 |
|
2015 |
Zaveri NT, Bertrand S, Yasuda D, Bertrand D. Functional characterization of AT-1001, an α3β4 nicotinic acetylcholine receptor ligand, at human α3β4 and α4β2 nAChR. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 17: 361-7. PMID 25180076 DOI: 10.1093/Ntr/Ntu170 |
0.511 |
|
2014 |
Chen S, Gopalakrishnan R, Schaer T, Marger F, Hovius R, Bertrand D, Pojer F, Heinis C. Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides. Nature Chemistry. 6: 1009-16. PMID 25343607 DOI: 10.1038/Nchem.2043 |
0.325 |
|
2014 |
Sahdeo S, Wallace T, Hirakawa R, Knoflach F, Bertrand D, Maag H, Misner D, Tombaugh GC, Santarelli L, Brameld K, Milla ME, Button DC. Characterization of RO5126946, a Novel α7 nicotinic acetylcholine receptor-positive allosteric modulator. The Journal of Pharmacology and Experimental Therapeutics. 350: 455-68. PMID 24917542 DOI: 10.1124/Jpet.113.210963 |
0.495 |
|
2014 |
Juneja P, Horlacher R, Bertrand D, Krause R, Marger F, Welte W. An internally modulated, thermostable, pH-sensitive Cys loop receptor from the hydrothermal vent worm Alvinella pompejana. The Journal of Biological Chemistry. 289: 15130-40. PMID 24719323 DOI: 10.1074/Jbc.M113.525576 |
0.381 |
|
2014 |
Bürgi JJ, Awale M, Boss SD, Schaer T, Marger F, Viveros-Paredes JM, Bertrand S, Gertsch J, Bertrand D, Reymond JL. Discovery of potent positive allosteric modulators of the α3β2 nicotinic acetylcholine receptor by a chemical space walk in ChEMBL. Acs Chemical Neuroscience. 5: 346-59. PMID 24593915 DOI: 10.1021/Cn4002297 |
0.459 |
|
2014 |
Rollema H, Russ C, Lee TC, Hurst RS, Bertrand D. Functional interactions of varenicline and nicotine with nAChR subtypes implicated in cardiovascular control. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 16: 733-42. PMID 24406270 DOI: 10.1093/Ntr/Ntt208 |
0.495 |
|
2013 |
Prestori F, Bonardi C, Mapelli L, Lombardo P, Goselink R, De Stefano ME, Gandolfi D, Mapelli J, Bertrand D, Schonewille M, De Zeeuw C, D'Angelo E. Gating of long-term potentiation by nicotinic acetylcholine receptors at the cerebellum input stage. Plos One. 8: e64828. PMID 23741401 DOI: 10.1371/Journal.Pone.0064828 |
0.396 |
|
2013 |
Stornaiuolo M, De Kloe GE, Rucktooa P, Fish A, van Elk R, Edink ES, Bertrand D, Smit AB, de Esch IJ, Sixma TK. Assembly of a π-π stack of ligands in the binding site of an acetylcholine-binding protein. Nature Communications. 4: 1875. PMID 23695669 DOI: 10.1038/Ncomms2900 |
0.366 |
|
2013 |
Dani JA, Donnelly-Roberts D, Bertrand D. Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science--editorial comments. Biochemical Pharmacology. 86: 1041. PMID 23684691 DOI: 10.1016/j.bcp.2013.05.002 |
0.331 |
|
2013 |
Wallace TL, Bertrand D. Importance of the nicotinic acetylcholine receptor system in the prefrontal cortex. Biochemical Pharmacology. 85: 1713-20. PMID 23628449 DOI: 10.1016/J.Bcp.2013.04.001 |
0.451 |
|
2013 |
Spurny R, Billen B, Howard RJ, Brams M, Debaveye S, Price KL, Weston DA, Strelkov SV, Tytgat J, Bertrand S, Bertrand D, Lummis SC, Ulens C. Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC). The Journal of Biological Chemistry. 288: 8355-64. PMID 23364792 DOI: 10.1074/Jbc.M112.424507 |
0.395 |
|
2013 |
Wallace TL, Bertrand D. Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia. Expert Opinion On Therapeutic Targets. 17: 139-55. PMID 23231385 DOI: 10.1517/14728222.2013.736498 |
0.428 |
|
2013 |
Hurst R, Rollema H, Bertrand D. Nicotinic acetylcholine receptors: from basic science to therapeutics. Pharmacology & Therapeutics. 137: 22-54. PMID 22925690 DOI: 10.1016/J.Pharmthera.2012.08.012 |
0.549 |
|
2012 |
Spurny R, Ramerstorfer J, Price K, Brams M, Ernst M, Nury H, Verheij M, Legrand P, Bertrand D, Bertrand S, Dougherty DA, de Esch IJ, Corringer PJ, Sieghart W, Lummis SC, et al. Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines. Proceedings of the National Academy of Sciences of the United States of America. 109: E3028-34. PMID 23035248 DOI: 10.1073/Pnas.1208208109 |
0.329 |
|
2012 |
Billen B, Spurny R, Brams M, van Elk R, Valera-Kummer S, Yakel JL, Voets T, Bertrand D, Smit AB, Ulens C. Molecular actions of smoking cessation drugs at α4β2 nicotinic receptors defined in crystal structures of a homologous binding protein. Proceedings of the National Academy of Sciences of the United States of America. 109: 9173-8. PMID 22619328 DOI: 10.1073/Pnas.1116397109 |
0.465 |
|
2012 |
Utkin YN, Weise C, Kasheverov IE, Andreeva TV, Kryukova EV, Zhmak MN, Starkov VG, Hoang NA, Bertrand D, Ramerstorfer J, Sieghart W, Thompson AJ, Lummis SC, Tsetlin VI. Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 287: 27079-86. PMID 22613724 DOI: 10.1074/Jbc.M112.363051 |
0.423 |
|
2012 |
Bréthous L, Garcia-Delgado N, Schwartz J, Bertrand S, Bertrand D, Reymond JL. Synthesis and nicotinic receptor activity of chemical space analogues of N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide (PNU-282,987) and 1,4-diazabicyclo[3.2.2]nonane-4-carboxylic acid 4-bromophenyl ester (SSR180711). Journal of Medicinal Chemistry. 55: 4605-18. PMID 22591063 DOI: 10.1021/Jm300030R |
0.499 |
|
2012 |
Favreau P, Benoit E, Hocking HG, Carlier L, D' hoedt D, Leipold E, Markgraf R, Schlumberger S, Córdova MA, Gaertner H, Paolini-Bertrand M, Hartley O, Tytgat J, Heinemann SH, Bertrand D, et al. A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors. British Journal of Pharmacology. 166: 1654-68. PMID 22229737 DOI: 10.1111/J.1476-5381.2012.01837.X |
0.387 |
|
2012 |
Osipov AV, Rucktooa P, Kasheverov IE, Filkin SY, Starkov VG, Andreeva TV, Sixma TK, Bertrand D, Utkin YN, Tsetlin VI. Dimeric α-cobratoxin X-ray structure: localization of intermolecular disulfides and possible mode of binding to nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 287: 6725-34. PMID 22223648 DOI: 10.1074/Jbc.M111.322313 |
0.356 |
|
2012 |
Prickaerts J, van Goethem NP, Chesworth R, Shapiro G, Boess FG, Methfessel C, Reneerkens OA, Flood DG, Hilt D, Gawryl M, Bertrand S, Bertrand D, König G. EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors. Neuropharmacology. 62: 1099-110. PMID 22085888 DOI: 10.1016/J.Neuropharm.2011.10.024 |
0.419 |
|
2012 |
Murray TA, Bertrand D, Papke RL, George AA, Pantoja R, Srinivasan R, Liu Q, Wu J, Whiteaker P, Lester HA, Lukas RJ. α7β2 nicotinic acetylcholine receptors assemble, function, and are activated primarily via their α7-α7 interfaces. Molecular Pharmacology. 81: 175-88. PMID 22039094 DOI: 10.1124/Mol.111.074088 |
0.769 |
|
2012 |
Steinlein OK, Hoda JC, Bertrand S, Bertrand D. Mutations in familial nocturnal frontal lobe epilepsy might be associated with distinct neurological phenotypes. Seizure. 21: 118-23. PMID 22036597 DOI: 10.1016/J.Seizure.2011.10.003 |
0.333 |
|
2011 |
Blum LC, van Deursen R, Bertrand S, Mayer M, Bürgi JJ, Bertrand D, Reymond JL. Discovery of α7-nicotinic receptor ligands by virtual screening of the chemical universe database GDB-13. Journal of Chemical Information and Modeling. 51: 3105-12. PMID 22077916 DOI: 10.1021/Ci200410U |
0.427 |
|
2011 |
Akdemir A, Rucktooa P, Jongejan A, Elk Rv, Bertrand S, Sixma TK, Bertrand D, Smit AB, Leurs R, de Graaf C, de Esch IJ. Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors. Bioorganic & Medicinal Chemistry. 19: 6107-19. PMID 21920761 DOI: 10.1016/J.Bmc.2011.08.028 |
0.45 |
|
2011 |
Reymond JL, van Deursen R, Bertrand D. What we have learned from crystal structures of proteins to receptor function. Biochemical Pharmacology. 82: 1521-7. PMID 21787757 DOI: 10.1016/J.Bcp.2011.07.061 |
0.403 |
|
2011 |
Pucci L, Grazioso G, Dallanoce C, Rizzi L, De Micheli C, Clementi F, Bertrand S, Bertrand D, Longhi R, De Amici M, Gotti C. Engineering of α-conotoxin MII-derived peptides with increased selectivity for native α6β2* nicotinic acetylcholine receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3775-89. PMID 21778325 DOI: 10.1096/Fj.10-179853 |
0.431 |
|
2011 |
Araud T, Graw S, Berger R, Lee M, Neveu E, Bertrand D, Leonard S. The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of α7*nAChR function. Biochemical Pharmacology. 82: 904-14. PMID 21718690 DOI: 10.1016/J.Bcp.2011.06.018 |
0.436 |
|
2011 |
Donnelly-Roberts D, Bertrand D, Gopalakrishnan M. Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science--Editorial Comments. Biochemical Pharmacology. 82: 797. PMID 21600889 DOI: 10.1016/j.bcp.2011.05.002 |
0.331 |
|
2011 |
Czarnetzki C, Schiffer E, Lysakowski C, Haller G, Bertrand D, Tramèr MR. Transcutaneous nicotine does not prevent postoperative nausea and vomiting: a randomized controlled trial. British Journal of Clinical Pharmacology. 71: 383-90. PMID 21284697 DOI: 10.1111/J.1365-2125.2010.03844.X |
0.383 |
|
2011 |
Lyukmanova EN, Shenkarev ZO, Shulepko MA, Mineev KS, D'Hoedt D, Kasheverov IE, Filkin SY, Krivolapova AP, Janickova H, Dolezal V, Dolgikh DA, Arseniev AS, Bertrand D, Tsetlin VI, Kirpichnikov MP. NMR structure and action on nicotinic acetylcholine receptors of water-soluble domain of human LYNX1. The Journal of Biological Chemistry. 286: 10618-27. PMID 21252236 DOI: 10.1074/jbc.M110.189100 |
0.375 |
|
2011 |
Wallace TL, Callahan PM, Tehim A, Bertrand D, Tombaugh G, Wang S, Xie W, Rowe WB, Ong V, Graham E, Terry AV, Rodefer JS, Herbert B, Murray M, Porter R, et al. RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents. The Journal of Pharmacology and Experimental Therapeutics. 336: 242-53. PMID 20959364 DOI: 10.1124/Jpet.110.171892 |
0.409 |
|
2011 |
Blum L, van Deursen R, Bürgi J, Reymond J, Maver M, Bertrand S, Bertrand D. Discovery of nicotinic acetylcholine receptor ligands in the chemical universe database GDB-13 Biochemical Pharmacology. 82: 1027. DOI: 10.1016/J.Bcp.2011.07.014 |
0.507 |
|
2011 |
Wallace TL, Porter R, Neveu E, Bertrand D. Effects of RG3487 at the α7β2 nicotinic acetylcholine receptor expressed in Xenopus oocytes Biochemical Pharmacology. 82: 1026-1027. DOI: 10.1016/J.Bcp.2011.07.012 |
0.512 |
|
2011 |
von Euler G, Bertrand D, Johnson E. Comparison of pharmacologic properties of AZD3480 and AZD1446 on neuronal nicotinic receptor subtypes Biochemical Pharmacology. 82: 1026. DOI: 10.1016/J.BCP.2011.07.011 |
0.425 |
|
2011 |
Bertrand S, Neveu E, Bertrand D, Gotti C. The conundrum of the α5 nicotinic acetylcholine receptor subunit Biochemical Pharmacology. 82: 1023. DOI: 10.1016/J.Bcp.2011.07.004 |
0.516 |
|
2010 |
Garcia-Delgado N, Bertrand S, Nguyen KT, van Deursen R, Bertrand D, Reymond JL. Exploring α7-Nicotinic Receptor Ligand Diversity by Scaffold Enumeration from the Chemical Universe Database GDB. Acs Medicinal Chemistry Letters. 1: 422-6. PMID 24900227 DOI: 10.1021/Ml100125F |
0.488 |
|
2010 |
Bertrand D. Neurocircuitry of the nicotinic cholinergic system. Dialogues in Clinical Neuroscience. 12: 463-70. PMID 21319492 |
0.377 |
|
2010 |
Bertrand D, Bertrand S, Neveu E, Fernandes P. Molecular characterization of off-target activities of telithromycin: a potential role for nicotinic acetylcholine receptors. Antimicrobial Agents and Chemotherapy. 54: 5399-402. PMID 20855733 DOI: 10.1128/Aac.00840-10 |
0.452 |
|
2010 |
Araud T, Wonnacott S, Bertrand D. Associated proteins: The universal toolbox controlling ligand gated ion channel function Biochemical Pharmacology. 80: 160-169. PMID 20346921 DOI: 10.1016/J.Bcp.2010.03.017 |
0.39 |
|
2010 |
Rollema H, Shrikhande A, Ward KM, Tingley FD, Coe JW, O'Neill BT, Tseng E, Wang EQ, Mather RJ, Hurst RS, Williams KE, de Vries M, Cremers T, Bertrand S, Bertrand D. Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence. British Journal of Pharmacology. 160: 334-45. PMID 20331614 DOI: 10.1111/J.1476-5381.2010.00682.X |
0.504 |
|
2010 |
Roy A, Zhou X, Chong MZ, D'hoedt D, Foo CS, Rajagopalan N, Nirthanan S, Bertrand D, Sivaraman J, Kini RM. Structural and functional characterization of a novel homodimeric three-finger neurotoxin from the venom of Ophiophagus hannah (king cobra). The Journal of Biological Chemistry. 285: 8302-15. PMID 20071329 DOI: 10.1074/Jbc.M109.074161 |
0.414 |
|
2010 |
Steinlein OK, Bertrand D. Nicotinic receptor channelopathies and epilepsy. Pflugers Archiv : European Journal of Physiology. 460: 495-503. PMID 20016990 DOI: 10.1007/S00424-009-0766-8 |
0.439 |
|
2009 |
Kasheverov IE, Zhmak MN, Fish A, Rucktooa P, Khruschov AY, Osipov AV, Ziganshin RH, D'hoedt D, Bertrand D, Sixma TK, Smit AB, Tsetlin VI. Interaction of alpha-conotoxin ImII and its analogs with nicotinic receptors and acetylcholine-binding proteins: additional binding sites on Torpedo receptor. Journal of Neurochemistry. 111: 934-44. PMID 19712060 DOI: 10.1111/J.1471-4159.2009.06359.X |
0.43 |
|
2009 |
Bertrand D, Gopalakrishnan M, Donnelly-Roberts D. Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research and Clinical Science-Editorial Perspective Biochemical Pharmacology. 78: 657. PMID 19576180 DOI: 10.1016/J.Bcp.2009.06.101 |
0.437 |
|
2009 |
Etter JF, Hoda JC, Perroud N, Munafò M, Buresi C, Duret C, Neidhart E, Malafosse A, Bertrand D. Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence. Addictive Behaviors. 34: 772-5. PMID 19482438 DOI: 10.1016/J.Addbeh.2009.05.010 |
0.357 |
|
2009 |
Nguyen KT, Luethi E, Syed S, Urwyler S, Bertrand S, Bertrand D, Reymond JL. 3-(aminomethyl)piperazine-2,5-dione as a novel NMDA glycine site inhibitor from the chemical universe database GDB. Bioorganic & Medicinal Chemistry Letters. 19: 3832-5. PMID 19394821 DOI: 10.1016/J.Bmcl.2009.04.021 |
0.315 |
|
2009 |
Hoda JC, Wanischeck M, Bertrand D, Steinlein OK. Pleiotropic functional effects of the first epilepsy-associated mutation in the human CHRNA2 gene. Febs Letters. 583: 1599-604. PMID 19383498 DOI: 10.1016/J.Febslet.2009.04.024 |
0.461 |
|
2009 |
D'hoedt D, Bertrand D. Nicotinic acetylcholine receptors: an overview on drug discovery. Expert Opinion On Therapeutic Targets. 13: 395-411. PMID 19335063 DOI: 10.1517/14728220902841045 |
0.559 |
|
2009 |
Ulens C, Akdemir A, Jongejan A, van Elk R, Bertrand S, Perrakis A, Leurs R, Smit AB, Sixma TK, Bertrand D, de Esch IJ. Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis. Journal of Medicinal Chemistry. 52: 2372-83. PMID 19331415 DOI: 10.1021/Jm801400G |
0.481 |
|
2009 |
Gilbert D, Lecchi M, Arnaudeau S, Bertrand D, Demaurex N. Local and global calcium signals associated with the opening of neuronal alpha7 nicotinic acetylcholine receptors. Cell Calcium. 45: 198-207. PMID 19038445 DOI: 10.1016/J.Ceca.2008.10.003 |
0.448 |
|
2009 |
Bertrand D, Bertrand S, Fernandes P. Importance of nicotinic acetylcholine receptors in the visual adverse effects associated with telithromycin Biochemical Pharmacology. 78: 922. DOI: 10.1016/J.Bcp.2009.06.087 |
0.466 |
|
2009 |
Rollema H, Shrikhande A, Ward K, Coe J, Tseng E, Wang E, De Vries M, Cremers T, Bertrand S, Bertrand D. Preclinical properties of the α4β2 nAChR partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence Biochemical Pharmacology. 78: 918-919. DOI: 10.1016/J.Bcp.2009.06.077 |
0.446 |
|
2009 |
Prestori F, Bertrand D, D’Angelo E. Nicotinic receptor activation increases glutamatergic transmission and plasticity in the rat cerebellum Biochemical Pharmacology. 78: 908-909. DOI: 10.1016/J.Bcp.2009.06.052 |
0.459 |
|
2009 |
Garcia N, Nguyen K, Bertrand S, Bertrand D, Reymond J. Novel α7 nAChRs ligands: From virtual screening to functional assays Biochemical Pharmacology. 78: 907. DOI: 10.1016/J.Bcp.2009.06.049 |
0.316 |
|
2009 |
Araud T, Wanischeck M, Benfante R, Steinlein O, Fornasari D, Bertrand D, Hoda J. Functional expression of an α5β2 nicotinic acetylcholine receptor Biochemical Pharmacology. 78: 901. DOI: 10.1016/J.Bcp.2009.06.035 |
0.515 |
|
2008 |
Nguyen KT, Syed S, Urwyler S, Bertrand S, Bertrand D, Reymond JL. Discovery of NMDA glycine site inhibitors from the chemical universe database GDB. Chemmedchem. 3: 1520-4. PMID 18792895 DOI: 10.1002/Cmdc.200800198 |
0.388 |
|
2008 |
Steinlein OK, Bertrand D. Neuronal nicotinic acetylcholine receptors: from the genetic analysis to neurological diseases. Biochemical Pharmacology. 76: 1175-83. PMID 18691557 DOI: 10.1016/J.Bcp.2008.07.012 |
0.461 |
|
2008 |
Ogier R, Tribollet E, Bertrand D, Raggenbass M. Pudendal motoneurons of the rat located in separated spinal nuclei possess nicotinic acetylcholine receptors having distinct pharmacological profiles. The European Journal of Neuroscience. 28: 924-30. PMID 18691331 DOI: 10.1111/J.1460-9568.2008.06403.X |
0.473 |
|
2008 |
Bertrand D, Bertrand S, Cassar S, Gubbins E, Li J, Gopalakrishnan M. Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment. Molecular Pharmacology. 74: 1407-16. PMID 18678621 DOI: 10.1124/Mol.107.042820 |
0.476 |
|
2008 |
Hoda JC, Gu W, Friedli M, Phillips HA, Bertrand S, Antonarakis SE, Goudie D, Roberts R, Scheffer IE, Marini C, Patel J, Berkovic SF, Mulley JC, Steinlein OK, Bertrand D. Human nocturnal frontal lobe epilepsy: pharmocogenomic profiles of pathogenic nicotinic acetylcholine receptor beta-subunit mutations outside the ion channel pore. Molecular Pharmacology. 74: 379-91. PMID 18456869 DOI: 10.1124/Mol.107.044545 |
0.441 |
|
2008 |
Osipov AV, Kasheverov IE, Makarova YV, Starkov VG, Vorontsova OV, Ziganshin RKh, Andreeva TV, Serebryakova MV, Benoit A, Hogg RC, Bertrand D, Tsetlin VI, Utkin YN. Naturally occurring disulfide-bound dimers of three-fingered toxins: a paradigm for biological activity diversification. The Journal of Biological Chemistry. 283: 14571-80. PMID 18381281 DOI: 10.1074/Jbc.M802085200 |
0.428 |
|
2008 |
Hogg RC, Bandelier F, Benoit A, Dosch R, Bertrand D. An automated system for intracellular and intranuclear injection. Journal of Neuroscience Methods. 169: 65-75. PMID 18243328 DOI: 10.1016/J.Jneumeth.2007.11.028 |
0.308 |
|
2008 |
Walsh H, Govind AP, Mastro R, Hoda JC, Bertrand D, Vallejo Y, Green WN. Up-regulation of nicotinic receptors by nicotine varies with receptor subtype. The Journal of Biological Chemistry. 283: 6022-32. PMID 18174175 DOI: 10.1074/Jbc.M703432200 |
0.566 |
|
2008 |
Hogg RC, Bertrand D. Neurotoxins acting at nicotinic receptors Future Neurology. 3: 463-472. DOI: 10.2217/14796708.3.4.463 |
0.47 |
|
2007 |
Gopalakrishnan M, Bertrand D, Williams M. Nicotinic acetylcholine receptors as therapeutic targets: emerging frontiers in basic research and clinical science - Editorial comments Biochemical Pharmacology. 74: 1091. PMID 17889037 DOI: 10.1016/j.bcp.2007.09.007 |
0.331 |
|
2007 |
Bertrand D, Gopalakrishnan M. Allosteric modulation of nicotinic acetylcholine receptors Biochemical Pharmacology. 74: 1155-1163. PMID 17707779 DOI: 10.1016/J.Bcp.2007.07.011 |
0.499 |
|
2007 |
Gu W, Bertrand D, Steinlein OK. A major role of the nicotinic acetylcholine receptor gene CHRNA2 in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is unlikely. Neuroscience Letters. 422: 74-6. PMID 17602836 DOI: 10.1016/J.Neulet.2007.06.006 |
0.38 |
|
2007 |
Lyukmanova EN, Shenkarev ZO, Schulga AA, Ermolyuk YS, Mordvintsev DY, Utkin YN, Shoulepko MA, Hogg RC, Bertrand D, Dolgikh DA, Tsetlin VI, Kirpichnikov MP. Bacterial expression, NMR, and electrophysiology analysis of chimeric short/long-chain alpha-neurotoxins acting on neuronal nicotinic receptors. The Journal of Biological Chemistry. 282: 24784-91. PMID 17576769 DOI: 10.1074/Jbc.M611263200 |
0.466 |
|
2007 |
Zoffmann S, Bertrand S, Do QT, Bertrand D, Rognan D, Hibert M, Galzi JL. Topological analysis of the complex formed between neurokinin A and the NK2 tachykinin receptor. Journal of Neurochemistry. 101: 506-16. PMID 17402972 DOI: 10.1111/J.1471-4159.2007.04473.X |
0.304 |
|
2007 |
Grandl J, Sakr E, Kotzyba-Hibert F, Krieger F, Bertrand S, Bertrand D, Vogel H, Goeldner M, Hovius R. Fluorescent epibatidine agonists for neuronal and muscle-type nicotinic acetylcholine receptors. Angewandte Chemie (International Ed. in English). 46: 3505-8. PMID 17385777 DOI: 10.1002/Anie.200604807 |
0.447 |
|
2007 |
Dani JA, Bertrand D. Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system. Annual Review of Pharmacology and Toxicology. 47: 699-729. PMID 17009926 DOI: 10.1146/Annurev.Pharmtox.47.120505.105214 |
0.545 |
|
2007 |
Hogg RC, Bertrand D. Partial agonists as therapeutic agents at neuronal nicotinic acetylcholine receptors. Biochemical Pharmacology. 73: 459-68. PMID 16979139 DOI: 10.1016/J.Bcp.2006.08.010 |
0.53 |
|
2006 |
Tsetlin VI, Kasheverov IE, Zhmak MN, Utkin YN, Vulfius CA, Smit AB, Bertrand D. Alpha-conotoxin analogs with enhanced affinity for nicotinic receptors and acetylcholine-binding proteins. Journal of Molecular Neuroscience : Mn. 30: 77-8. PMID 17192636 DOI: 10.1385/Jmn:30:1:77 |
0.46 |
|
2006 |
Sakr E, Kotzyba-Hibert F, Grande J, Hovius R, Vogel H, Bertrand S, Bertrand D, Goeldner M. Engineered site-directed labeling of nicotinic acetylcholine receptors using reactive epibatidine derivatives: appraisal of epibatidine-docking models in neuronal and muscular receptors. Journal of Molecular Neuroscience : Mn. 30: 35-6. PMID 17192618 DOI: 10.1385/Jmn:30:1:35 |
0.515 |
|
2006 |
Mourot A, Rodrigo J, Bertrand S, Bertrand D, Goeldner M, Kotzyba-Hibert F. Reorganization of the nicotinic acetylcholine receptor during desensitization probed with a photoactivatable agonist. Journal of Molecular Neuroscience : Mn. 30: 13-4. PMID 17192607 DOI: 10.1385/Jmn:30:1:13 |
0.501 |
|
2006 |
Smit AB, Celie PH, Kasheverov IE, Mordvintsev DY, van Nierop P, Bertrand D, Tsetlin V, Sixma TK. Acetylcholine-binding proteins: functional and structural homologs of nicotinic acetylcholine receptors. Journal of Molecular Neuroscience : Mn. 30: 9-10. PMID 17192605 DOI: 10.1385/Jmn:30:1:9 |
0.532 |
|
2006 |
Steidl EM, Neveu E, Bertrand D, Buisson B. The adult rat hippocampal slice revisited with multi-electrode arrays. Brain Research. 1096: 70-84. PMID 16716268 DOI: 10.1016/J.Brainres.2006.04.034 |
0.338 |
|
2006 |
Ulens C, Hogg RC, Celie PH, Bertrand D, Tsetlin V, Smit AB, Sixma TK. Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP. Proceedings of the National Academy of Sciences of the United States of America. 103: 3615-20. PMID 16505382 DOI: 10.1073/Pnas.0507889103 |
0.481 |
|
2006 |
Hoda JC, Krause R, Bertrand S, Bertrand D. Unexpected sensitivity of the human alpha7 neuronal nicotinic acetylcholine receptor to aminoglycosides. Neuroreport. 17: 65-70. PMID 16361952 DOI: 10.1097/01.Wnr.0000192736.85287.2F |
0.517 |
|
2006 |
van Nierop P, Bertrand S, Munno DW, Gouwenberg Y, van Minnen J, Spafford JD, Syed NI, Bertrand D, Smit AB. Identification and functional expression of a family of nicotinic acetylcholine receptor subunits in the central nervous system of the mollusc Lymnaea stagnalis. The Journal of Biological Chemistry. 281: 1680-91. PMID 16286458 DOI: 10.1074/Jbc.M508571200 |
0.419 |
|
2006 |
Mourot A, Rodrigo J, Kotzyba-Hibert F, Bertrand S, Bertrand D, Goeldner M. Probing the reorganization of the nicotinic acetylcholine receptor during desensitization by time-resolved covalent labeling using [3H]AC5, a photoactivatable agonist. Molecular Pharmacology. 69: 452-61. PMID 16269537 DOI: 10.1124/Mol.105.017566 |
0.506 |
|
2005 |
van Nierop P, Keramidas A, Bertrand S, van Minnen J, Gouwenberg Y, Bertrand D, Smit AB. Identification of molluscan nicotinic acetylcholine receptor (nAChR) subunits involved in formation of cation- and anion-selective nAChRs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10617-26. PMID 16291934 DOI: 10.1523/Jneurosci.2015-05.2005 |
0.548 |
|
2005 |
Charpantier E, Wiesner A, Huh KH, Ogier R, Hoda JC, Allaman G, Raggenbass M, Feuerbach D, Bertrand D, Fuhrer C. Alpha7 neuronal nicotinic acetylcholine receptors are negatively regulated by tyrosine phosphorylation and Src-family kinases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9836-49. PMID 16251431 DOI: 10.1523/Jneurosci.3497-05.2005 |
0.488 |
|
2005 |
Hogg RC, Buisson B, Bertrand D. Allosteric modulation of ligand-gated ion channels. Biochemical Pharmacology. 70: 1267-76. PMID 16043127 DOI: 10.1016/J.Bcp.2005.06.010 |
0.353 |
|
2005 |
Lecchi M, McIntosh JM, Bertrand S, Safran AB, Bertrand D. Functional properties of neuronal nicotinic acetylcholine receptors in the chick retina during development. The European Journal of Neuroscience. 21: 3182-8. PMID 15978026 DOI: 10.1111/J.1460-9568.2005.04150.X |
0.544 |
|
2005 |
Celie PH, Kasheverov IE, Mordvintsev DY, Hogg RC, van Nierop P, van Elk R, van Rossum-Fikkert SE, Zhmak MN, Bertrand D, Tsetlin V, Sixma TK, Smit AB. Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant. Nature Structural & Molecular Biology. 12: 582-8. PMID 15951818 DOI: 10.1038/Nsmb951 |
0.528 |
|
2005 |
Vallejo YF, Buisson B, Bertrand D, Green WN. Chronic nicotine exposure upregulates nicotinic receptors by a novel mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5563-72. PMID 15944384 DOI: 10.1523/Jneurosci.5240-04.2005 |
0.541 |
|
2005 |
Hurst RS, Hajós M, Raggenbass M, Wall TM, Higdon NR, Lawson JA, Rutherford-Root KL, Berkenpas MB, Hoffmann WE, Piotrowski DW, Groppi VE, Allaman G, Ogier R, Bertrand S, Bertrand D, et al. A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4396-405. PMID 15858066 DOI: 10.1523/Jneurosci.5269-04.2005 |
0.521 |
|
2004 |
Bertrand S, Bertrand D. Overview of electrophysiological characterization of neuronal nicotinic acetylcholine receptors. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit11.7. PMID 21956810 DOI: 10.1002/0471141755.Ph1107S23 |
0.549 |
|
2004 |
Ogier R, Liu X, Tribollet E, Bertrand D, Raggenbass M. Identified spinal motoneurons of young rats possess nicotinic acetylcholine receptors of the heteromeric family. The European Journal of Neuroscience. 20: 2591-7. PMID 15548202 DOI: 10.1111/J.1460-9568.2004.03746.X |
0.487 |
|
2004 |
Itier V, Schönbächler R, Tribollet E, Honer M, Prinz K, Marguerat A, Bertrand S, Bunnelle WH, Schubiger PA, Meyer MD, Sullivan JP, Bertrand D, Westera G. A-186253, a specific antagonist of the alpha 4 beta 2 nAChRs: its properties and potential to study brain nicotinic acetylcholine receptors. Neuropharmacology. 47: 538-57. PMID 15380372 DOI: 10.1016/J.Neuropharm.2004.05.006 |
0.548 |
|
2004 |
Hogg RC, Bertrand D. Nicotinic acetylcholine receptors as drug targets. Current Drug Targets. Cns and Neurological Disorders. 3: 123-30. PMID 15078187 DOI: 10.2174/1568007043482507 |
0.423 |
|
2004 |
Lecchi M, Marguerat A, Ionescu A, Pelizzone M, Renaud P, Sommerhalder J, Safran AB, Tribollet E, Bertrand D. Ganglion cells from chick retina display multiple functional nAChR subtypes. Neuroreport. 15: 307-11. PMID 15076758 DOI: 10.1097/00001756-200402090-00019 |
0.49 |
|
2004 |
Hogg RC, Bertrand D. Neuronal nicotinic receptors and epilepsy, from genes to possible therapeutic compounds. Bioorganic & Medicinal Chemistry Letters. 14: 1859-61. PMID 15050616 DOI: 10.1016/J.Bmcl.2003.10.075 |
0.456 |
|
2004 |
Tribollet E, Bertrand D, Marguerat A, Raggenbass M. Comparative distribution of nicotinic receptor subtypes during development, adulthood and aging: an autoradiographic study in the rat brain. Neuroscience. 124: 405-20. PMID 14980390 DOI: 10.1016/J.Neuroscience.2003.09.028 |
0.503 |
|
2004 |
Hogg RC, Bertrand D. Regulating the regulators: the role of nicotinic acetylcholine receptors in human epilepsy. Drug News & Perspectives. 16: 261-6. PMID 12942156 DOI: 10.1358/DNP.2003.16.5.829313 |
0.377 |
|
2004 |
Nirthanan S, Charpantier E, Gopalakrishnakone P, Gwee MC, Khoo HE, Cheah LS, Kini RM, Bertrand D. Neuromuscular effects of candoxin, a novel toxin from the venom of the Malayan krait (Bungarus candidus). British Journal of Pharmacology. 139: 832-44. PMID 12813007 DOI: 10.1038/Sj.Bjp.0705299 |
0.436 |
|
2003 |
Chimienti F, Hogg RC, Plantard L, Lehmann C, Brakch N, Fischer J, Huber M, Bertrand D, Hohl D. Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda. Human Molecular Genetics. 12: 3017-24. PMID 14506129 DOI: 10.1093/Hmg/Ddg320 |
0.442 |
|
2003 |
Leniger T, Kananura C, Hufnagel A, Bertrand S, Bertrand D, Steinlein OK. A new Chrna4 mutation with low penetrance in nocturnal frontal lobe epilepsy. Epilepsia. 44: 981-5. PMID 12823585 DOI: 10.1046/J.1528-1157.2003.61102.X |
0.396 |
|
2003 |
Hogg RC, Raggenbass M, Bertrand D. Nicotinic acetylcholine receptors: from structure to brain function. Reviews of Physiology, Biochemistry and Pharmacology. 147: 1-46. PMID 12783266 DOI: 10.1007/S10254-003-0005-1 |
0.573 |
|
2003 |
Hogg RC, Hopping G, Alewood PF, Adams DJ, Bertrand D. Alpha-conotoxins PnIA and [A10L]PnIA stabilize different states of the alpha7-L247T nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 278: 26908-14. PMID 12746432 DOI: 10.1074/Jbc.M212628200 |
0.472 |
|
2003 |
Che C, Petit G, Kotzyba-Hibert F, Bertrand S, Bertrand D, Grutter T, Goeldner M. Syntheses and biological properties of cysteine-reactive epibatidine derivatives. Bioorganic & Medicinal Chemistry Letters. 13: 1001-4. PMID 12643898 DOI: 10.1016/S0960-894X(03)00092-1 |
0.416 |
|
2003 |
Raggenbass M, Bertrand D. Nicotinic receptors in circuit excitability and epilepsy. Journal of Neurobiology. 53: 580-9. PMID 12436422 DOI: 10.1002/Neu.10152 |
0.528 |
|
2002 |
Grutter T, Bertrand S, Kotzyba-Hibert F, Bertrand D, Goeldner M. Structural reorganization of the acetylcholine binding site of the torpedo nicotinic receptor as revealed by dynamic photoaffinity labeling. Chembiochem : a European Journal of Chemical Biology. 3: 652-8. PMID 12324999 DOI: 10.1002/1439-7633(20020703)3:7<652::Aid-Cbic652>3.0.Co;2-L |
0.512 |
|
2002 |
Bertrand D, Picard F, Le Hellard S, Weiland S, Favre I, Phillips H, Bertrand S, Berkovic SF, Malafosse A, Mulley J. How mutations in the nAChRs can cause ADNFLE epilepsy. Epilepsia. 43: 112-22. PMID 12121305 DOI: 10.1046/J.1528-1157.43.S.5.16.X |
0.482 |
|
2002 |
Itier V, Bertrand D. Mutations of the neuronal nicotinic acetylcholine receptors and their association with ADNFLE. Neurophysiologie Clinique = Clinical Neurophysiology. 32: 99-107. PMID 12035491 DOI: 10.1016/S0987-7053(02)00294-0 |
0.462 |
|
2002 |
Villiger Y, Szanto I, Jaconi S, Blanchet C, Buisson B, Krause KH, Bertrand D, Romand JA. Expression of an alpha7 duplicate nicotinic acetylcholine receptor-related protein in human leukocytes. Journal of Neuroimmunology. 126: 86-98. PMID 12020960 DOI: 10.1016/S0165-5728(02)00057-7 |
0.498 |
|
2002 |
Zaninetti M, Tribollet E, Bertrand D, Raggenbass M. Nicotinic cholinergic activation of magnocellular neurons of the hypothalamic paraventricular nucleus. Neuroscience. 110: 287-99. PMID 11958870 DOI: 10.1016/S0306-4522(01)00536-X |
0.562 |
|
2002 |
Nirthanan S, Charpantier E, Gopalakrishnakone P, Gwee MC, Khoo HE, Cheah LS, Bertrand D, Kini RM. Candoxin, a novel toxin from Bungarus candidus, is a reversible antagonist of muscle (alphabetagammadelta ) but a poorly reversible antagonist of neuronal alpha 7 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 277: 17811-20. PMID 11884390 DOI: 10.1074/Jbc.M111152200 |
0.414 |
|
2002 |
Buisson B, Bertrand D. Nicotine addiction: the possible role of functional upregulation. Trends in Pharmacological Sciences. 23: 130-6. PMID 11879680 DOI: 10.1016/S0165-6147(00)01979-9 |
0.522 |
|
2002 |
Tassonyi E, Charpantier E, Muller D, Dumont L, Bertrand D. The role of nicotinic acetylcholine receptors in the mechanisms of anesthesia. Brain Research Bulletin. 57: 133-50. PMID 11849819 DOI: 10.1016/S0361-9230(01)00740-7 |
0.583 |
|
2002 |
Tribollet E, Bertrand D, Raggenbass M. Role of neuronal nicotinic receptors in the transmission and processing of information in neurons of the central nervous system. Pharmacology, Biochemistry, and Behavior. 70: 457-66. PMID 11796145 DOI: 10.1016/S0091-3057(01)00700-6 |
0.525 |
|
2002 |
Sgard F, Charpantier E, Bertrand S, Walker N, Caput D, Graham D, Bertrand D, Besnard F. A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit. Molecular Pharmacology. 61: 150-9. PMID 11752216 DOI: 10.1124/Mol.61.1.150 |
0.415 |
|
2002 |
Curtis L, Buisson B, Bertrand S, Bertrand D. Potentiation of human alpha4beta2 neuronal nicotinic acetylcholine receptor by estradiol. Molecular Pharmacology. 61: 127-35. PMID 11752213 DOI: 10.1124/Mol.61.1.127 |
0.546 |
|
2001 |
Moulard B, Picard F, le Hellard S, Agulhon C, Weiland S, Favre I, Bertrand S, Malafosse A, Bertrand D. Ion channel variation causes epilepsies. Brain Research. Brain Research Reviews. 36: 275-84. PMID 11690625 DOI: 10.1016/S0165-0173(01)00104-7 |
0.379 |
|
2001 |
Itier V, Bertrand D. Neuronal nicotinic receptors: from protein structure to function. Febs Letters. 504: 118-25. PMID 11532443 DOI: 10.1016/S0014-5793(01)02702-8 |
0.509 |
|
2001 |
Leonard S, Bertrand D. Neuronal nicotinic receptors: from structure to function. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 3: 203-23. PMID 11506765 DOI: 10.1080/14622200110050213 |
0.449 |
|
2001 |
Lukas RJ, Lucero L, Buisson B, Galzi JL, Puchacz E, Fryer JD, Changeux JP, Bertrand D. Neurotoxicity of channel mutations in heterologously expressed alpha7-nicotinic acetylcholine receptors. The European Journal of Neuroscience. 13: 1849-60. PMID 11403678 DOI: 10.1046/J.0953-816X.2001.01560.X |
0.497 |
|
2001 |
Chiodini F, Charpantier E, Muller D, Tassonyi E, Fuchs-Buder T, Bertrand D. Blockade and activation of the human neuronal nicotinic acetylcholine receptors by atracurium and laudanosine Anesthesiology. 94: 643-651. PMID 11379686 DOI: 10.1097/00000542-200104000-00019 |
0.524 |
|
2001 |
Bohler S, Gay S, Bertrand S, Corringer PJ, Edelstein SJ, Changeux JP, Bertrand D. Desensitization of neuronal nicotinic acetylcholine receptors conferred by N-terminal segments of the beta 2 subunit. Biochemistry. 40: 2066-74. PMID 11329274 DOI: 10.1021/Bi0020022 |
0.432 |
|
2001 |
Buisson B, Bertrand D. Chronic Exposure to Nicotine Upregulates the Human α4β2 Nicotinic Acetylcholine Receptor Function The Journal of Neuroscience. 21: 1819-1829. DOI: 10.1523/Jneurosci.21-06-01819.2001 |
0.519 |
|
2000 |
Phillips HA, Favre I, Kirkpatrick M, Zuberi SM, Goudie D, Heron SE, Scheffer IE, Sutherland GR, Berkovic SF, Bertrand D, Mulley JC. CHRNB2 is the second acetylcholine receptor subunit associated with autosomal dominant nocturnal frontal lobe epilepsy. American Journal of Human Genetics. 68: 225-31. PMID 11104662 DOI: 10.1086/316946 |
0.418 |
|
2000 |
Buisson B, Vallejo YF, Green WN, Bertrand D. The unusual nature of epibatidine responses at the alpha4beta2 nicotinic acetylcholine receptor. Neuropharmacology. 39: 2561-9. PMID 11044727 DOI: 10.1016/S0028-3908(00)00158-1 |
0.553 |
|
2000 |
Weiland S, Bertrand D, Leonard S. Neuronal nicotinic acetylcholine receptors: From the gene to the disease Behavioural Brain Research. 113: 43-56. PMID 10942031 DOI: 10.1016/S0166-4328(00)00199-6 |
0.533 |
|
2000 |
Spang JE, Bertrand S, Westera G, Patt JT, Schubiger PA, Bertrand D. Chemical modification of epibatidine causes a switch from agonist to antagonist and modifies its selectivity for neuronal nicotinic acetylcholine receptors. Chemistry & Biology. 7: 545-55. PMID 10903939 DOI: 10.1016/S1074-5521(00)00138-1 |
0.526 |
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2000 |
Schulz R, Bertrand S, Chamaon K, Smalla KH, Gundelfinger ED, Bertrand D. Neuronal nicotinic acetylcholine receptors from Drosophila: two different types of alpha subunits coassemble within the same receptor complex. Journal of Neurochemistry. 74: 2537-46. PMID 10820216 DOI: 10.1046/J.1471-4159.2000.0742537.X |
0.522 |
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2000 |
Curtis L, Chiodini F, Spang JE, Bertrand S, Patt JT, Westera G, Bertrand D. A new look at the neuronal nicotinic acetylcholine receptor pharmacophore. European Journal of Pharmacology. 393: 155-63. PMID 10771009 DOI: 10.1016/S0014-2999(00)00053-4 |
0.523 |
|
2000 |
Zaninetti M, Blanchet C, Tribollet E, Bertrand D, Raggenbass M. Magnocellular neurons of the rat supraoptic nucleus are endowed with functional nicotinic acetylcholine receptors. Neuroscience. 95: 319-23. PMID 10658610 DOI: 10.1016/S0306-4522(99)00477-7 |
0.559 |
|
1999 |
Gilles N, Blanchet C, Shichor I, Zaninetti M, Lotan I, Bertrand D, Gordon D. A scorpion alpha-like toxin that is active on insects and mammals reveals an unexpected specificity and distribution of sodium channel subtypes in rat brain neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8730-9. PMID 10516292 DOI: 10.1523/Jneurosci.19-20-08730.1999 |
0.385 |
|
1999 |
Picard F, Bertrand S, Steinlein OK, Bertrand D. Mutated nicotinic receptors responsible for autosomal dominant nocturnal frontal lobe epilepsy are more sensitive to carbamazepine. Epilepsia. 40: 1198-209. PMID 10487182 DOI: 10.1111/J.1528-1157.1999.Tb00848.X |
0.535 |
|
1999 |
Corringer PJ, Bertrand S, Galzi JL, Devillers-Thiéry A, Changeux JP, Bertrand D. Molecular basis of the charge selectivity of nicotinic acetylcholine receptor and related ligand-gated ion channels. Novartis Foundation Symposium. 225: 215-24; discussion 2. PMID 10472058 DOI: 10.1002/9780470515716.Ch14 |
0.517 |
|
1999 |
Zaninetti M, Tribollet E, Bertrand D, Raggenbass M. Presence of functional neuronal nicotinic acetylcholine receptors in brainstem motoneurons of the rat. The European Journal of Neuroscience. 11: 2737-48. PMID 10457170 DOI: 10.1046/J.1460-9568.1999.00689.X |
0.497 |
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1999 |
Williams BM, Temburni MK, Bertrand S, Bertrand D, Jacob MH. The long cytoplasmic loop of the alpha 3 subunit targets specific nAChR subtypes to synapses on neurons in vivo. Annals of the New York Academy of Sciences. 868: 640-4. PMID 10414348 DOI: 10.1111/J.1749-6632.1999.Tb11340.X |
0.41 |
|
1999 |
Chiodini FC, Tassonyi E, Hulo S, Bertrand D, Muller D. Modulation of synaptic transmission by nicotine and nicotinic antagonists in hippocampus Brain Research Bulletin. 48: 623-628. PMID 10386843 DOI: 10.1016/S0361-9230(99)00043-X |
0.516 |
|
1999 |
Bertrand S, Patt JT, Spang JE, Westera G, Schubiger PA, Bertrand D. Neuronal nAChR stereoselectivity to non-natural epibatidine derivatives. Febs Letters. 450: 273-9. PMID 10359088 DOI: 10.1016/S0014-5793(99)00473-1 |
0.458 |
|
1999 |
Corringer PJ, Bertrand S, Galzi JL, Devillers-Thiéry A, Changeux JP, Bertrand D. Mutational analysis of the charge selectivity filter of the alpha7 nicotinic acetylcholine receptor. Neuron. 22: 831-43. PMID 10230802 DOI: 10.1016/S0896-6273(00)80741-2 |
0.448 |
|
1999 |
Hefft S, Hulo S, Bertrand D, Muller D. Synaptic transmission at nicotinic acetylcholine receptors in rat hippocampal organotypic cultures and slices Journal of Physiology. 515: 769-776. PMID 10066903 DOI: 10.1111/J.1469-7793.1999.769Ab.X |
0.447 |
|
1999 |
Agulhon C, Charnay Y, Vallet P, Abitbol M, Kobetz A, Bertrand D, Malafosse A. Corrigendum to: distribution of mRNA for the alpha-subunit of the nicotinic acetylcholine receptor in the human fetal brain Brain Research. Molecular Brain Research. 63: 384. PMID 9878844 DOI: 10.1016/S0169-328X(98)00319-2 |
0.484 |
|
1998 |
Williams BM, Temburni MK, Levey MS, Bertrand S, Bertrand D, Jacob MH. The long internal loop of the alpha 3 subunit targets nAChRs to subdomains within individual synapses on neurons in vivo. Nature Neuroscience. 1: 557-62. PMID 10196562 DOI: 10.1038/2792 |
0.468 |
|
1998 |
Bertrand S, Weiland S, Berkovic SF, Steinlein OK, Bertrand D. Properties of neuronal nicotinic acetylcholine receptor mutants from humans suffering from autosomal dominant nocturnal frontal lobe epilepsy. British Journal of Pharmacology. 125: 751-60. PMID 9831911 DOI: 10.1038/Sj.Bjp.0702154 |
0.492 |
|
1998 |
Servent D, Thanh HL, Antil S, Bertrand D, Corringer PJ, Changeux JP, Ménez A. Functional determinants by which snake and cone snail toxins block the alpha 7 neuronal nicotinic acetylcholine receptors. Journal of Physiology, Paris. 92: 107-11. PMID 9782452 DOI: 10.1016/S0928-4257(98)80146-0 |
0.544 |
|
1998 |
Buisson B, Bertrand D. Allosteric modulation of neuronal nicotinic acetylcholine receptors. Journal of Physiology, Paris. 92: 89-100. PMID 9782450 DOI: 10.1016/S0928-4257(98)80144-7 |
0.533 |
|
1998 |
Agulhon C, Charnay Y, Vallet P, Abitbol M, Kobetz A, Bertrand D, Malafosse A. Distribution of mRNA for the alpha4 subunit of the nicotinic acetylcholine receptor in the human fetal brain. Brain Research. Molecular Brain Research. 58: 123-31. PMID 9685607 DOI: 10.1016/S0169-328X(98)00113-2 |
0.428 |
|
1998 |
Schulz R, Sawruk E, Mülhardt C, Bertrand S, Baumann A, Phannavong B, Betz H, Bertrand D, Gundelfinger ED, Schmitt B. D alpha3, a new functional alpha subunit of nicotinic acetylcholine receptors from Drosophila. Journal of Neurochemistry. 71: 853-62. PMID 9681478 DOI: 10.1046/J.1471-4159.1998.71020853.X |
0.462 |
|
1998 |
Chiodini FC, Tassonyi E, Fuchs-Buder T, Fathi M, Bertrand D, Muller D. Effects of neuromuscular blocking agents on excitatory transmission and γ-aminobutyric acid(A)-mediated inhibition in the rat hippocampal slice Anesthesiology. 88: 1003-1013. PMID 9579510 DOI: 10.1097/00000542-199804000-00021 |
0.317 |
|
1998 |
Buisson B, Bertrand D. Open-channel blockers at the human alpha4beta2 neuronal nicotinic acetylcholine receptor. Molecular Pharmacology. 53: 555-63. PMID 9495824 DOI: 10.1124/Mol.53.3.555 |
0.469 |
|
1998 |
Krause RM, Buisson B, Bertrand S, Corringer PJ, Galzi JL, Changeux JP, Bertrand D. Ivermectin: a positive allosteric effector of the alpha7 neuronal nicotinic acetylcholine receptor. Molecular Pharmacology. 53: 283-94. PMID 9463487 DOI: 10.1124/Mol.53.2.283 |
0.482 |
|
1998 |
Corringer PJ, Bertrand S, Bohler S, Edelstein SJ, Changeux JP, Bertrand D. Critical elements determining diversity in agonist binding and desensitization of neuronal nicotinic acetylcholine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 648-57. PMID 9425007 DOI: 10.1523/Jneurosci.18-02-00648.1998 |
0.524 |
|
1998 |
Ménez A, Mourier G, Kessler P, Ducancel F, Bertrand D, Corringer PJ, Changeux JP, Servent D. Artificial toxins to explore new receptors Journal of Physiology-Paris. 92: 468. DOI: 10.1016/S0928-4257(99)80084-9 |
0.403 |
|
1998 |
Corringer P, Bertrand S, Bohler S, Edelstein S, Bertrand D, Changeux J. 25 Critical elements determining diversity in agonist binding and desensitization of neuronal nAChR Journal of Physiology-Paris. 92: 424-425. DOI: 10.1016/S0928-4257(99)80037-0 |
0.384 |
|
1998 |
Chiodini F, Bertrand S, Tassonyi E, Muller D, Bertrand D. 21 Effects of atracurium, a neuromuscular blocking agent, on reconstituted human neuronal nicotinic acetylcholine receptors Journal of Physiology-Paris. 92: 420-421. DOI: 10.1016/S0928-4257(99)80033-3 |
0.497 |
|
1998 |
Buisson B, Bertrand S, Bertrand D. Human neuronal nicotinic acetylcholine receptors (nAChRs) may participate in the sexual dimorphism functionality of the brain Journal of Physiology-Paris. 92: 416-417. DOI: 10.1016/S0928-4257(99)80029-1 |
0.459 |
|
1998 |
Bohler S, Corringer P, Changeux J, Bertrand S, Bertrand D, Edelstein S. Regulation of desensitization by beta subunit in neuronal nAchR Journal of Physiology-Paris. 92: 414. DOI: 10.1016/S0928-4257(99)80026-6 |
0.356 |
|
1998 |
Servent D, Antil S, Bertrand D, Rochette S, Rivaille P, Jolivet M, Ménez A. Structure and function of nicotinic acetylcholine receptor ligands Toxicology Letters. 95: 10. DOI: 10.1016/S0378-4274(98)80039-8 |
0.506 |
|
1998 |
Bertrand D. Overview of Electrophysiology Current Protocols in Pharmacology. 3. DOI: 10.1002/0471141755.Ph1101S03 |
0.338 |
|
1997 |
Bertrand S, Devillers-Thiéry A, Palma E, Buisson B, Edelstein SJ, Corringer PJ, Changeux JP, Bertrand D. Paradoxical allosteric effects of competitive inhibitors on neuronal alpha7 nicotinic receptor mutants. Neuroreport. 8: 3591-6. PMID 9427332 DOI: 10.1097/00001756-199711100-00034 |
0.448 |
|
1997 |
Servent D, Winckler-Dietrich V, Hu HY, Kessler P, Drevet P, Bertrand D, Ménez A. Only snake curaremimetic toxins with a fifth disulfide bond have high affinity for the neuronal alpha7 nicotinic receptor. The Journal of Biological Chemistry. 272: 24279-86. PMID 9305882 DOI: 10.1074/Jbc.272.39.24279 |
0.393 |
|
1997 |
Steinlein OK, Magnusson A, Stoodt J, Bertrand S, Weiland S, Berkovic SF, Nakken KO, Propping P, Bertrand D. An insertion mutation of the CHRNA4 gene in a family with autosomal dominant nocturnal frontal lobe epilepsy. Human Molecular Genetics. 6: 943-7. PMID 9175743 DOI: 10.1093/Hmg/6.6.943 |
0.394 |
|
1997 |
Bertrand D, Buisson B, Krause RM, Hu HY, Bertrand S. Electrophysiology: a method to investigate the functional properties of ligand-gated channels. Journal of Receptor and Signal Transduction Research. 17: 227-42. PMID 9029493 DOI: 10.3109/10799899709036606 |
0.389 |
|
1996 |
Palma E, Bertrand S, Binzoni T, Bertrand D. Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine. The Journal of Physiology. 491: 151-61. PMID 9011607 DOI: 10.1113/Jphysiol.1996.Sp021203 |
0.531 |
|
1996 |
Edelstein SJ, Schaad O, Henry E, Bertrand D, Changeux JP. A kinetic mechanism for nicotinic acetylcholine receptors based on multiple allosteric transitions. Biological Cybernetics. 75: 361-79. PMID 8983160 DOI: 10.1007/S004220050302 |
0.401 |
|
1996 |
Ballivet M, Alliod C, Bertrand S, Bertrand D. Nicotinic acetylcholine receptors in the nematode Caenorhabditis elegans. Journal of Molecular Biology. 258: 261-9. PMID 8627624 DOI: 10.1006/Jmbi.1996.0248 |
0.522 |
|
1996 |
Buisson B, Gopalakrishnan M, Arneric SP, Sullivan JP, Bertrand D. Human α4β2 Neuronal Nicotinic Acetylcholine Receptor in HEK 293 Cells: A Patch-Clamp Study The Journal of Neuroscience. 16: 7880-7891. DOI: 10.1523/Jneurosci.16-24-07880.1996 |
0.508 |
|
1996 |
Galzi JL, Bertrand S, Corringer PJ, Changeux JP, Bertrand D. Identification of calcium binding sites that regulate potentiation of a neuronal nicotinic acetylcholine receptor. The Embo Journal. 15: 5824-5832. DOI: 10.1002/j.1460-2075.1996.tb00969.x |
0.372 |
|
1995 |
Forster I, Bertrand D. Inward rectification of neuronal nicotinic acetylcholine receptors investigated by using the homomeric alpha 7 receptor. Proceedings. Biological Sciences. 260: 139-48. PMID 7784432 DOI: 10.1098/rspb.1995.0071 |
0.482 |
|
1995 |
Corringer PJ, Galzi JL, Eiselé JL, Bertrand S, Changeux JP, Bertrand D. Identification of a new component of the agonist binding site of the nicotinic alpha 7 homooligomeric receptor. The Journal of Biological Chemistry. 270: 11749-52. PMID 7744821 DOI: 10.1074/Jbc.270.20.11749 |
0.504 |
|
1995 |
Gopalakrishnan M, Buisson B, Touma E, Giordano T, Campbell JE, Hu IC, Donnelly-Roberts D, Arneric SP, Bertrand D, Sullivan JP. Stable expression and pharmacological properties of the human alpha 7 nicotinic acetylcholine receptor. European Journal of Pharmacology. 290: 237-46. PMID 7589218 DOI: 10.1016/0922-4106(95)00083-6 |
0.501 |
|
1995 |
Bertrand D, Changeux JP. Nicotinic receptor: An allosteric protein specialized for intercellular communication Seminars in the Neurosciences. 7: 75-90. DOI: 10.1006/Smns.1995.0010 |
0.513 |
|
1994 |
Bertrand D, Ballivet M, Gomez M, Bertrand S, Phannavong B, Gundelfinger ED. Physiological properties of neuronal nicotinic receptors reconstituted from the vertebrate beta 2 subunit and Drosophila alpha subunits. The European Journal of Neuroscience. 6: 869-75. PMID 8075828 DOI: 10.1111/J.1460-9568.1994.Tb00997.X |
0.486 |
|
1994 |
Gotti C, Hanke W, Maury K, Moretti M, Ballivet M, Cementi F, Bertrand D. Pharmacology and biophysical properties of α7 and α7-α8 α-Bungarotoxin receptor subtypes immunopurified from the chick optic lobe European Journal of Neuroscience. 6: 1281-1291. PMID 7981870 DOI: 10.1111/J.1460-9568.1994.Tb00318.X |
0.418 |
|
1994 |
Puchacz E, Buisson B, Bertrand D, Lukas RJ. Functional expression of nicotinic acetylcholine receptors containing rat alpha 7 subunits in human SH-SY5Y neuroblastoma cells. Febs Letters. 354: 155-9. PMID 7957916 DOI: 10.1016/0014-5793(94)01108-7 |
0.466 |
|
1994 |
Hussy N, Ballivet M, Bertrand D. Agonist and antagonist effects of nicotine on chick neuronal nicotinic receptors are defined by α and β subunits Journal of Neurophysiology. 72: 1317-1326. PMID 7807214 DOI: 10.1152/jn.1994.72.3.1317 |
0.427 |
|
1993 |
Eiselé JL, Bertrand S, Galzi JL, Devillers-Thiéry A, Changeux JP, Bertrand D. Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities. Nature. 366: 479-83. PMID 8247158 DOI: 10.1038/366479A0 |
0.47 |
|
1993 |
Bertrand D, Galzi JL, Devillers-Thiéry A, Bertrand S, Changeux JP. Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 90: 6971-5. PMID 7688468 DOI: 10.1073/Pnas.90.15.6971 |
0.434 |
|
1993 |
Devillers-Thiéry A, Galzi JL, Eiselé JL, Bertrand S, Bertrand D, Changeux JP. Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels. The Journal of Membrane Biology. 136: 97-112. PMID 7508983 DOI: 10.1007/BF02505755 |
0.391 |
|
1993 |
Bertrand D, Galzi JL, Devillers-Thiéry A, Bertrand S, Changeux JP. Stratification of the channel domain in neurotransmitter receptors. Current Opinion in Cell Biology. 5: 688-93. PMID 7504932 DOI: 10.1016/0955-0674(93)90141-C |
0.341 |
|
1992 |
Drasdo A, Caulfield M, Bertrand D, Bertrand S, Wonnacott S. Methyl lycaconitine: A novel nicotinic antagonist. Molecular and Cellular Neurosciences. 3: 237-43. PMID 19912865 DOI: 10.1016/1044-7431(92)90043-2 |
0.528 |
|
1992 |
Bertrand D, Devillers-Thiéry A, Revah F, Galzi JL, Hussy N, Mulle C, Bertrand S, Ballivet M, Changeux JP. Unconventional pharmacology of a neuronal nicotinic receptor mutated in the channel domain. Proceedings of the National Academy of Sciences of the United States of America. 89: 1261-5. PMID 1741378 DOI: 10.1073/Pnas.89.4.1261 |
0.526 |
|
1992 |
Bertrand D, Bertrand S, Ballivet M. Pharmacological properties of the homomeric alpha 7 receptor. Neuroscience Letters. 146: 87-90. PMID 1475054 DOI: 10.1016/0304-3940(92)90179-B |
0.534 |
|
1992 |
Valera S, Ballivet M, Bertrand D. Progesterone modulates a neuronal nicotinic acetylcholine receptor Proceedings of the National Academy of Sciences of the United States of America. 89: 9949-9953. PMID 1409725 DOI: 10.1073/Pnas.89.20.9949 |
0.567 |
|
1992 |
Changeux JP, Devillers-Thiéry A, Galzi JL, Bertrand D. New mutants to explore nicotinic receptor functions. Trends in Pharmacological Sciences. 13: 299-301. PMID 1384213 DOI: 10.1016/0165-6147(92)90094-M |
0.492 |
|
1992 |
Galzi JL, Devillers-Thiéry A, Hussy N, Bertrand S, Changeux JP, Bertrand D. Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic. Nature. 359: 500-5. PMID 1383829 DOI: 10.1038/359500A0 |
0.481 |
|
1992 |
Eggerickx D, Raspe E, Bertrand D, Vassart G, Parmentier M. Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene. Biochemical and Biophysical Research Communications. 187: 1306-13. PMID 1329734 DOI: 10.1016/0006-291X(92)90445-Q |
0.308 |
|
1992 |
Changeux JP, Galzi JL, Devillers-Thiéry A, Bertrand D. The functional architecture of the acetylcholine nicotinic receptor explored by affinity labelling and site-directed mutagenesis. Quarterly Reviews of Biophysics. 25: 395-432. PMID 1293635 DOI: 10.1017/S0033583500004352 |
0.365 |
|
1992 |
Devillers-Thiéry A, Galzi JL, Bertrand S, Changeux JP, Bertrand D. Stratified organization of the nicotinic acetylcholine receptor channel. Neuroreport. 3: 1001-4. PMID 1282832 DOI: 10.1097/00001756-199211000-00014 |
0.364 |
|
1992 |
Drasdo A, Caulfield M, Bertrand D, Bertrand S, Wonnacott S. Methyl lycaconitine: A novel nicotinic antagonist Molecular and Cellular Neuroscience. 3: 237-243. DOI: 10.1016/1044-7431(92)90043-2 |
0.438 |
|
1992 |
Matter J, Matter-Sadzinski L, Cooper E, Bertrand D, Ballivet M. Cloned neuronal nicotinic receptors Neurochemistry International. 21: Q17. DOI: 10.1016/0197-0186(92)91848-Q |
0.509 |
|
1991 |
Gross A, Ballivet M, Rungger D, Bertrand D. Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes: role of the α subunit in agonist sensitivity and desensitization PflüGers Archiv European Journal of Physiology. 419: 545-551. PMID 1775381 DOI: 10.1007/Bf00370805 |
0.461 |
|
1991 |
Galzi JL, Bertrand D, Devillers-Thiéry A, Revah F, Bertrand S, Changeux JP. Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis. Febs Letters. 294: 198-202. PMID 1756861 DOI: 10.1016/0014-5793(91)80668-S |
0.572 |
|
1991 |
Revah F, Bertrand D, Galzi JL, Devillers-Thiéry A, Mulle C, Hussy N, Bertrand S, Ballivet M, Changeux JP. Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor. Nature. 353: 846-9. PMID 1719423 DOI: 10.1038/353846A0 |
0.491 |
|
1991 |
Bertrand D, Valera S, Bertrand S, Ballivet M, Rungger D. Steroids inhibit nicotinic acetylcholine receptors. Neuroreport. 2: 277-80. PMID 1717043 DOI: 10.1097/00001756-199105000-00016 |
0.49 |
|
1991 |
Bertrand D, Cooper E, Valera S, Rungger D, Ballivet M. Electrophysiology of Neuronal Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes following Nuclear Injection of Genes or cDNAs Methods in Neurosciences. 4: 174-193. DOI: 10.1016/B978-0-12-185257-3.50017-3 |
0.51 |
|
1990 |
Haimann C, Bernheim L, Bertrand D, Bader CR. Potassium current activated by intracellular sodium in quail trigeminal ganglion neurons. The Journal of General Physiology. 95: 961-79. PMID 2163435 DOI: 10.1085/Jgp.95.5.961 |
0.31 |
|
1990 |
Bertrand D, Ballivet M, Rungger D. Activation and blocking of neuronal nicotinic acetylcholine receptor reconstituted in Xenopus oocytes Proceedings of the National Academy of Sciences of the United States of America. 87: 1993-1997. PMID 1968642 DOI: 10.1073/Pnas.87.5.1993 |
0.502 |
|
1990 |
Couturier S, Bertrand D, Matter JM, Hernandez MC, Bertrand S, Millar N, Valera S, Barkas T, Ballivet M. A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX Neuron. 5: 847-856. PMID 1702646 DOI: 10.1016/0896-6273(90)90344-F |
0.469 |
|
1990 |
Couturier S, Erkman L, Valera S, Rungger D, Bertrand S, Boulter J, Ballivet M, Bertrand D. Alpha 5, alpha 3, and non-alpha 3. Three clustered avian genes encoding neuronal nicotinic acetylcholine receptor-related subunits. Journal of Biological Chemistry. 265: 17560-17567. DOI: 10.1016/S0021-9258(18)38201-2 |
0.351 |
|
1988 |
Ballivet M, Nef P, Couturier S, Rungger D, Bader CR, Bertrand D, Cooper E. Electrophysiology of a chick neuronal nicotinic acetylcholine receptor expressed in xenopus oocytes after cDNA injection Neuron. 1: 847-852. PMID 3272190 DOI: 10.1016/0896-6273(88)90132-8 |
0.553 |
|
1985 |
Bader CR, Bernheim L, Bertrand D. Sodium-activated potassium current in cultured avian neurones. Nature. 317: 540-2. PMID 2413369 DOI: 10.1038/317540A0 |
0.308 |
|
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