Louis Lefebvre - Publications

Affiliations: 
Medical Genetics University of British Columbia, Vancouver, Vancouver, BC, Canada 

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Fang S, Chang KW, Lefebvre L. Roles of endogenous retroviral elements in the establishment and maintenance of imprinted gene expression. Frontiers in Cell and Developmental Biology. 12: 1369751. PMID 38505259 DOI: 10.3389/fcell.2024.1369751  0.428
2022 Akbari V, Hanlon VCT, O'Neill K, Lefebvre L, Schrader KA, Lansdorp PM, Jones SJM. Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq. Cell Genomics. 3: 100233. PMID 36777186 DOI: 10.1016/j.xgen.2022.100233  0.304
2022 Ito T, Kubiura-Ichimaru M, Murakami Y, Bogutz AB, Lefebvre L, Suetake I, Tajima S, Tada M. DNMT1 regulates the timing of DNA methylation by DNMT3 in an enzymatic activity-dependent manner in mouse embryonic stem cells. Plos One. 17: e0262277. PMID 34986190 DOI: 10.1371/journal.pone.0262277  0.338
2019 Bogutz AB, Brind'Amour J, Kobayashi H, Jensen KN, Nakabayashi K, Imai H, Lorincz MC, Lefebvre L. Evolution of imprinting via lineage-specific insertion of retroviral promoters. Nature Communications. 10: 5674. PMID 31831741 DOI: 10.1038/S41467-019-13662-9  0.548
2019 Xu Q, Xiang Y, Wang Q, Wang L, Brind'Amour J, Bogutz AB, Zhang Y, Zhang B, Yu G, Xia W, Du Z, Huang C, Ma J, Zheng H, Li Y, ... ... Lefebvre L, et al. SETD2 regulates the maternal epigenome, genomic imprinting and embryonic development. Nature Genetics. PMID 31040401 DOI: 10.1038/S41588-019-0398-7  0.453
2018 Tunster SJ, Van de Pette M, Creeth HDJ, Lefebvre L, John RM. Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann Syndrome. Disease Models & Mechanisms. PMID 30158284 DOI: 10.1242/Dmm.035832  0.489
2018 Brind'Amour J, Kobayashi H, Richard Albert J, Shirane K, Sakashita A, Kamio A, Bogutz A, Koike T, Karimi MM, Lefebvre L, Kono T, Lorincz MC. LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation. Nature Communications. 9: 3331. PMID 30127397 DOI: 10.1038/S41467-018-05841-X  0.451
2018 Bogutz AB, Oh-McGinnis R, Jacob KJ, Ho-Lau R, Gu T, Gertsenstein M, Nagy A, Lefebvre L. Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage. Plos Genetics. 14: e1007587. PMID 30096149 DOI: 10.1371/Journal.Pgen.1007587  0.58
2016 Branco MR, King M, Perez-Garcia V, Bogutz AB, Caley M, Fineberg E, Lefebvre L, Cook SJ, Dean W, Hemberger M, Reik W. Maternal DNA Methylation Regulates Early Trophoblast Development. Developmental Cell. 36: 152-63. PMID 26812015 DOI: 10.1016/J.Devcel.2015.12.027  0.433
2015 Kelsey AD, Yang C, Leung D, Minks J, Dixon-McDougall T, Baldry SE, Bogutz AB, Lefebvre L, Brown CJ. Impact of flanking chromosomal sequences on localization and silencing by the human non-coding RNA XIST. Genome Biology. 16: 208. PMID 26429547 DOI: 10.1186/S13059-015-0774-2  0.369
2014 Liu S, Brind'Amour J, Karimi MM, Shirane K, Bogutz A, Lefebvre L, Sasaki H, Shinkai Y, Lorincz MC. Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells. Genes & Development. 28: 2041-55. PMID 25228647 DOI: 10.1101/Gad.244848.114  0.445
2013 Jacob KJ, Robinson WP, Lefebvre L. Beckwith-Wiedemann and Silver-Russell syndromes: opposite developmental imbalances in imprinted regulators of placental function and embryonic growth. Clinical Genetics. 84: 326-34. PMID 23495910 DOI: 10.1111/Cge.12143  0.412
2012 Lefebvre L. Engineering of large deletions and duplications in vivo. Methods in Molecular Biology (Clifton, N.J.). 925: 137-46. PMID 22907494 DOI: 10.1007/978-1-62703-011-3_8  0.446
2012 Lefebvre L. The placental imprintome and imprinted gene function in the trophoblast glycogen cell lineage. Reproductive Biomedicine Online. 25: 44-57. PMID 22560119 DOI: 10.1016/J.Rbmo.2012.03.019  0.523
2012 MacIsaac JL, Bogutz AB, Morrissy AS, Lefebvre L. Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2. Nucleic Acids Research. 40: 1523-35. PMID 22053079 DOI: 10.1093/Nar/Gkr871  0.511
2011 Jones MJ, Bogutz AB, Lefebvre L. An extended domain of Kcnq1ot1 silencing revealed by an imprinted fluorescent reporter. Molecular and Cellular Biology. 31: 2827-37. PMID 21576366 DOI: 10.1128/Mcb.01435-10  0.654
2011 John RM, Lefebvre L. Developmental regulation of somatic imprints. Differentiation; Research in Biological Diversity. 81: 270-80. PMID 21316143 DOI: 10.1016/J.Diff.2011.01.007  0.533
2011 Oh-McGinnis R, Bogutz AB, Lefebvre L. Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction. Developmental Biology. 351: 277-86. PMID 21238448 DOI: 10.1016/J.Ydbio.2011.01.008  0.468
2010 Oh-McGinnis R, Jones MJ, Lefebvre L. Applications of the site-specific recombinase Cre to the study of genomic imprinting. Briefings in Functional Genomics. 9: 281-93. PMID 20601421 DOI: 10.1093/Bfgp/Elq017  0.623
2010 Oh-McGinnis R, Bogutz AB, Lee KY, Higgins MJ, Lefebvre L. Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome. Bmc Developmental Biology. 10: 50. PMID 20459838 DOI: 10.1186/1471-213X-10-50  0.554
2009 Yuen RK, Avila L, Peñaherrera MS, von Dadelszen P, Lefebvre L, Kobor MS, Robinson WP. Human placental-specific epipolymorphism and its association with adverse pregnancy outcomes. Plos One. 4: e7389. PMID 19838307 DOI: 10.1371/Journal.Pone.0007389  0.607
2009 Jones MJ, Lefebvre L. An imprinted GFP insertion reveals long-range epigenetic regulation in embryonic lineages. Developmental Biology. 336: 42-52. PMID 19778534 DOI: 10.1016/J.Ydbio.2009.09.023  0.678
2009 Lefebvre L, Mar L, Bogutz A, Oh-McGinnis R, Mandegar MA, Paderova J, Gertsenstein M, Squire JA, Nagy A. The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region. Human Molecular Genetics. 18: 4255-67. PMID 19684026 DOI: 10.1093/Hmg/Ddp379  0.598
2008 Oh R, Ho R, Mar L, Gertsenstein M, Paderova J, Hsien J, Squire JA, Higgins MJ, Nagy A, Lefebvre L. Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7. Molecular and Cellular Biology. 28: 1092-103. PMID 18039841 DOI: 10.1128/Mcb.01019-07  0.6
2004 Shi W, Lefebvre L, Yu Y, Otto S, Krella A, Orth A, Fundele R. Loss-of-imprinting of Peg1 in mouse interspecies hybrids is correlated with altered growth. Genesis (New York, N.Y. : 2000). 39: 65-72. PMID 15124229 DOI: 10.1002/Gene.20027  0.452
2001 Lefebvre L, Dionne N, Karaskova J, Squire JA, Nagy A. Selection for transgene homozygosity in embryonic stem cells results in extensive loss of heterozygosity. Nature Genetics. 27: 257-8. PMID 11242104 DOI: 10.1038/85808  0.534
1998 Lefebvre L, Viville S, Barton SC, Ishino F, Keverne EB, Surani MA. Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest. Nature Genetics. 20: 163-9. PMID 9771709 DOI: 10.1038/2464  0.481
1997 Tada M, Tada T, Lefebvre L, Barton SC, Surani MA. Embryonic germ cells induce epigenetic reprogramming of somatic nucleus in hybrid cells. The Embo Journal. 16: 6510-20. PMID 9351832 DOI: 10.1093/Emboj/16.21.6510  0.504
1997 Lefebvre L, Viville S, Barton SC, Ishino F, Surani MA. Genomic structure and parent-of-origin-specific methylation of Peg1. Human Molecular Genetics. 6: 1907-15. PMID 9302270 DOI: 10.1093/Hmg/6.11.1907  0.541
1993 Lefebvre L, Smith M. Mutational and functional analysis of dominant SPT2 (SIN1) suppressor alleles in Saccharomyces cerevisiae. Molecular and Cellular Biology. 13: 5393-407. PMID 8395004 DOI: 10.1128/Mcb.13.9.5393  0.461
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