Susanna Cotecchia - Publications

Affiliations: 
Duke University, Durham, NC 

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Vezzi V, Ambrosio C, Grò MC, Molinari P, Süral G, Costa T, Onaran HO, Cotecchia S. Vasopressin receptor 2 mutations in the nephrogenic syndrome of inappropriate antidiuresis show different mechanisms of constitutive activation for G protein coupled receptors. Scientific Reports. 10: 9111. PMID 32499611 DOI: 10.1038/s41598-020-65996-w  0.356
2012 Cotecchia S, Stanasila L, Diviani D. Protein-protein interactions at the adrenergic receptors. Current Drug Targets. 13: 15-27. PMID 21777184 DOI: 10.2174/138945012798868489  0.546
2010 Cotecchia S. Constitutive activity and inverse agonism at the α(₁a) and α(₁b) adrenergic receptor subtypes. Methods in Enzymology. 485: 123-38. PMID 21050914 DOI: 10.1016/B978-0-12-381296-4.00007-5  0.443
2010 Cotecchia S. The α1-adrenergic receptors: diversity of signaling networks and regulation. Journal of Receptor and Signal Transduction Research. 30: 410-9. PMID 20954794 DOI: 10.3109/10799893.2010.518152  0.413
2009 Sanbe A, Tanaka Y, Fujiwara Y, Miyauchi N, Mizutani R, Yamauchi J, Cotecchia S, Koike K, Tsujimoto G, Tanoue A. Enhanced vascular contractility in alpha1-adrenergic receptor-deficient mice. Life Sciences. 84: 713-8. PMID 19249315 DOI: 10.1016/J.Lfs.2009.02.020  0.419
2008 Stanasila L, Abuin L, Dey J, Cotecchia S. Different internalization properties of the alpha1a- and alpha1b-adrenergic receptor subtypes: the potential role of receptor interaction with beta-arrestins and AP50. Molecular Pharmacology. 74: 562-73. PMID 18523139 DOI: 10.1124/mol.107.043422  0.464
2007 Sanbe A, Tanaka Y, Fujiwara Y, Tsumura H, Yamauchi J, Cotecchia S, Koike K, Tsujimoto G, Tanoue A. α 1-Adrenoceptors are required for normal male sexual function British Journal of Pharmacology. 152: 332-340. PMID 17603545 DOI: 10.1038/Sj.Bjp.0707366  0.34
2007 Appert-Collin A, Cotecchia S, Nenniger-Tosato M, Pedrazzini T, Diviani D. The A-kinase anchoring protein (AKAP)-Lbc-signaling complex mediates alpha1 adrenergic receptor-induced cardiomyocyte hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 104: 10140-5. PMID 17537920 DOI: 10.1073/pnas.0701099104  0.38
2007 Cotecchia S. Constitutive activity and inverse agonism at the alpha1adrenoceptors. Biochemical Pharmacology. 73: 1076-83. PMID 17125741 DOI: 10.1016/j.bcp.2006.10.024  0.514
2006 Stanasila L, Abuin L, Diviani D, Cotecchia S. Ezrin directly interacts with the alpha1b-adrenergic receptor and plays a role in receptor recycling. The Journal of Biological Chemistry. 281: 4354-63. PMID 16352594 DOI: 10.1074/jbc.M511989200  0.498
2005 Costa T, Cotecchia S. Historical review: Negative efficacy and the constitutive activity of G-protein-coupled receptors. Trends in Pharmacological Sciences. 26: 618-24. PMID 16260046 DOI: 10.1016/j.tips.2005.10.009  0.43
2005 Hosoda C, Tanoue A, Shibano M, Tanaka Y, Hiroyama M, Koshimizu TA, Cotecchia S, Kitamura T, Tsujimoto G, Koike K. Correlation between vasoconstrictor roles and mRNA expression of alpha1-adrenoceptor subtypes in blood vessels of genetically engineered mice. British Journal of Pharmacology. 146: 456-66. PMID 16113694 DOI: 10.1038/Sj.Bjp.0706325  0.331
2005 Novi F, Stanasila L, Giorgi F, Corsini GU, Cotecchia S, Maggio R. Paired activation of two components within muscarinic M3 receptor dimers is required for recruitment of beta-arrestin-1 to the plasma membrane. The Journal of Biological Chemistry. 280: 19768-76. PMID 15769745 DOI: 10.1074/jbc.M411281200  0.424
2004 Auclair A, Drouin C, Cotecchia S, Glowinski J, Tassin JP. 5-HT2A and alpha1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants. The European Journal of Neuroscience. 20: 3073-84. PMID 15579162 DOI: 10.1111/j.1460-9568.2004.03805.x  0.327
2004 Townsend SA, Jung AS, Hoe YS, Lefkowitz RY, Khan SA, Lemmon CA, Harrison RW, Lee K, Barouch LA, Cotecchia S, Shoukas AA, Nyhan D, Hare JM, Berkowitz DE. Critical role for the alpha-1B adrenergic receptor at the sympathetic neuroeffector junction. Hypertension. 44: 776-82. PMID 15466664 DOI: 10.1161/01.HYP.0000145405.01113.0e  0.409
2004 Cotecchia S, Stanasila L, Diviani D, Björklöf K, Rossier O, Fanelli F. Structural determinants involved in the activation and regulation of G protein-coupled receptors: lessons from the alpha1-adrenegic receptor subtypes. Biology of the Cell. 96: 327-33. PMID 15207900 DOI: 10.1016/j.biolcel.2004.03.009  0.583
2003 Cotecchia S, Fanelli F, Costa T. Constitutively active G protein-coupled receptor mutants: implications on receptor function and drug action. Assay and Drug Development Technologies. 1: 311-6. PMID 15090196 DOI: 10.1089/15406580360545125  0.412
2003 Stanasila L, Perez JB, Vogel H, Cotecchia S. Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization. The Journal of Biological Chemistry. 278: 40239-51. PMID 12888550 DOI: 10.1074/Jbc.M306085200  0.515
2003 O'Connell TD, Ishizaka S, Nakamura A, Swigart PM, Rodrigo MC, Simpson GL, Cotecchia S, Rokosh DG, Grossman W, Foster E, Simpson PC. The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse. The Journal of Clinical Investigation. 111: 1783-91. PMID 12782680 DOI: 10.1172/Jci16100  0.325
2003 Diviani D, Lattion AL, Abuin L, Staub O, Cotecchia S. The adaptor complex 2 directly interacts with the alpha 1b-adrenergic receptor and plays a role in receptor endocytosis. The Journal of Biological Chemistry. 278: 19331-40. PMID 12644451 DOI: 10.1074/jbc.M302110200  0.564
2002 Cotecchia S, Björklöf K, Rossier O, Stanasila L, Greasley P, Fanelli F. The alpha1b-adrenergic receptor subtype: molecular properties and physiological implications. Journal of Receptor and Signal Transduction Research. 22: 1-16. PMID 12503605 DOI: 10.1081/RRS-120014585  0.549
2002 Stone EA, Cotecchia S, Lin Y, Quartermain D. Role of brain alpha 1B-adrenoceptors in modafinil-induced behavioral activity. Synapse (New York, N.Y.). 46: 269-70. PMID 12373742 DOI: 10.1002/syn.10127  0.366
2002 Greasley PJ, Fanelli F, Rossier O, Abuin L, Cotecchia S. Mutagenesis and modelling of the alpha(1b)-adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation. Molecular Pharmacology. 61: 1025-32. PMID 11961120  0.414
2002 Vecchione C, Fratta L, Rizzoni D, Notte A, Poulet R, Porteri E, Frati G, Guelfi D, Trimarco V, Mulvany MJ, Agabiti-Rosei E, Trimarco B, Cotecchia S, Lembo G. Cardiovascular influences of alpha1b-adrenergic receptor defect in mice. Circulation. 105: 1700-7. PMID 11940550 DOI: 10.1161/01.cir.0000012750.08480.55  0.511
2002 Del Carmine R, Ambrosio C, Sbraccia M, Cotecchia S, Ijzerman AP, Costa T. Mutations inducing divergent shifts of constitutive activity reveal different modes of binding among catecholamine analogues to the β 2-adrenergic receptor British Journal of Pharmacology. 135: 1715-1722. PMID 11934812 DOI: 10.1038/sj.bjp.0704622  0.375
2002 Björklöf K, Lundström K, Abuin L, Greasley PJ, Cotecchia S. Co- and posttranslational modification of the alpha(1B)-adrenergic receptor: effects on receptor expression and function. Biochemistry. 41: 4281-91. PMID 11914074  0.547
2002 Sugimoto Y, Fujisawa R, Tanimura R, Lattion AL, Cotecchia S, Tsujimoto G, Nagao T, Kurose H. Beta(1)-selective agonist (-)-1-(3,4-dimethoxyphenetylamino)-3-(3,4-dihydroxy)-2-propanol [(-)-RO363] differentially interacts with key amino acids responsible for beta(1)-selective binding in resting and active states. The Journal of Pharmacology and Experimental Therapeutics. 301: 51-8. PMID 11907156 DOI: 10.1124/JPET.301.1.51  0.568
2001 Greasley PJ, Fanelli F, Scheer A, Abuin L, Nenniger-Tosato M, DeBenedetti PG, Cotecchia S. Mutational and computational analysis of the alpha(1b)-adrenergic receptor. Involvement of basic and hydrophobic residues in receptor activation and G protein coupling. The Journal of Biological Chemistry. 276: 46485-94. PMID 11585821 DOI: 10.1074/jbc.M105791200  0.569
2001 Spreng M, Cotecchia S, Schenk F. A behavioral study of alpha-1b adrenergic receptor knockout mice: increased reaction to novelty and selectively reduced learning capacities. Neurobiology of Learning and Memory. 75: 214-229. PMID 11222061 DOI: 10.1006/Nlme.2000.3965  0.302
2001 Hein P, Goepel M, Cotecchia S, Michel MC. A quantitative analysis of antagonism and inverse agonism at wild-type and constitutively active hamster alpha1B-adrenoceptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 363: 34-9. PMID 11191834 DOI: 10.1007/s002100000329  0.349
2000 Cotecchia S, Rossier O, Fanelli F, Leonardi A, De Benedetti PG. The alpha 1a and alpha 1b-adrenergic receptor subtypes: molecular mechanisms of receptor activation and of drug action. Pharmaceutica Acta Helvetiae. 74: 173-9. PMID 10812955 DOI: 10.1016/S0031-6865(99)00031-X  0.584
1999 Fanelli F, Menziani C, Scheer A, Cotecchia S, De Benedetti PG. Theoretical study of the electrostatically driven step of receptor-G protein recognition. Proteins. 37: 145-56. PMID 10584061 DOI: 10.1002/(SICI)1097-0134(19991101)37:2<145::AID-PROT1>3.0.CO;2-R  0.471
1999 Rossier O, Abuin L, Fanelli F, Leonardi A, Cotecchia S. Inverse agonism and neutral antagonism at alpha(1a)- and alpha(1b)-adrenergic receptor subtypes. Molecular Pharmacology. 56: 858-66. PMID 10531388 DOI: 10.1124/MOL.56.5.858  0.402
1999 Pralong FP, Gomez F, Castillo E, Cotecchia S, Abuin L, Aubert ML, Portmann L, Gaillard RC. Complete hypogonadotropic hypogonadism associated with a novel inactivating mutation of the gonadotropin-releasing hormone receptor. The Journal of Clinical Endocrinology and Metabolism. 84: 3811-6. PMID 10523035 DOI: 10.1210/JCEM.84.10.6042  0.308
1999 Lattion A, Abuin L, Nenniger-Tosato M, Cotecchia S. Constitutively active mutants of the beta1-adrenergic receptor. Febs Letters. 457: 302-6. PMID 10471797 DOI: 10.1016/S0014-5793(99)01064-9  0.346
1999 Scheer A, Fanelli F, Diviani D, de Benedetti PG, Cotecchia S. Structure-function relationships of the alpha1b-adrenergic receptor. European Urology. 11-6. PMID 10393467 DOI: 10.1159/000052312  0.499
1999 Cotecchia S, Mhaouty-Kodja S. Regulatory mechanisms of alpha 1B-adrenergic receptor function. Biochemical Society Transactions. 27: 154-7. PMID 10093725 DOI: 10.1042/BST0270154  0.541
1999 Scheer A, Björklöf K, Cotecchia S, Lundstrom K. Expression of the α(1b)-adrenergic receptor and G protein subunits in mammalian cell lines using the Semliki Forest virus expression system Journal of Receptor and Signal Transduction Research. 19: 369-378. PMID 10071771 DOI: 10.3109/10799899909036658  0.428
1999 Mhaouty-Kodja S, Barak LS, Scheer A, Abuin L, Diviani D, Caron MG, Cotecchia S. Constitutively active alpha-1b adrenergic receptor mutants display different phosphorylation and internalization features. Molecular Pharmacology. 55: 339-47. PMID 9927627 DOI: 10.1124/MOL.55.2.339  0.613
1999 Debruyne FMJ, Poel HGvd, Groat WCd, Yoshiyama M, Ramage AG, Yamamoto T, Somogyi GT, Brading AF, McCoy R, Dass N, McGrath JC, Naghadeh MA, Pediani JD, Mackenzie JF, Daly CJ, ... ... Cotecchia S, et al. Abstracts, Poster Session European Urology. 36: 113-117. DOI: 10.1159/000052331  0.403
1999 Cotecchia S, Mhaouty-Kodja S, Diviani D, Scheer A. ACUTE AND CHRONIC REGULATION OF G PROTEIN-COUPLED RECEPTORS Biochemical Society Transactions. 27: A25-A25. DOI: 10.1042/bst027a025a  0.32
1999 Fanelli F, Menziani C, Scheer A, Cotecchia S, De Benedetti PG. Theoretical study on receptor-G protein recognition: New insights into the mechanism of the ?1b-adrenergic receptor activation International Journal of Quantum Chemistry. 73: 71-83. DOI: 10.1002/(SICI)1097-461X(1999)73:2<71::AID-QUA3>3.0.CO;2-3  0.499
1998 Cotecchia S, Scheer A, Diviani D, Fanelli F, De Benedetti PG. Molecular mechanisms involved in the activation and regulation of the alpha 1-adrenergic receptor subtypes. Farmaco (Societa Chimica Italiana : 1989). 53: 273-7. PMID 9658585 DOI: 10.1016/S0014-827X(98)00021-4  0.577
1998 Fanelli F, Menziani C, Scheer A, Cotecchia S, De Benedetti PG. Ab initio modeling and molecular dynamics simulation of the alpha 1b-adrenergic receptor activation. Methods (San Diego, Calif.). 14: 302-17. PMID 9571086 DOI: 10.1006/METH.1998.0586  0.387
1997 Diviani D, Lattion AL, Cotecchia S. Characterization of the phosphorylation sites involved in G protein-coupled receptor kinase- and protein kinase C-mediated desensitization of the alpha1B-adrenergic receptor. The Journal of Biological Chemistry. 272: 28712-9. PMID 9353340 DOI: 10.1074/jbc.272.45.28712  0.332
1997 Cavalli A, Lattion AL, Hummler E, Nenniger M, Pedrazzini T, Aubert JF, Michel MC, Yang M, Lembo G, Vecchione C, Mostardini M, Schmidt A, Beermann F, Cotecchia S. Decreased blood pressure response in mice deficient of the alpha1b-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 94: 11589-94. PMID 9326654 DOI: 10.1073/Pnas.94.21.11589  0.384
1997 Lee TW, Cotecchia S, Milligan G. Up-regulation of the levels of expression and function of a constitutively active mutant of the hamster alpha1B-adrenoceptor by ligands that act as inverse agonists. The Biochemical Journal. 733-9. PMID 9271095 DOI: 10.1042/BJ3250733  0.485
1997 Scheer A, Cotecchia S. Constitutively active G protein-coupled receptors: potential mechanisms of receptor activation. Journal of Receptor and Signal Transduction Research. 17: 57-73. PMID 9029481 DOI: 10.3109/10799899709036594  0.46
1997 Scheer A, Fanelli F, Costa T, De Benedetti PG, Cotecchia S. The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate. Proceedings of the National Academy of Sciences of the United States of America. 94: 808-13. PMID 9023338 DOI: 10.1073/PNAS.94.3.808  0.398
1997 Cavalli A, Fanelli F, Taddei C, De Benedetti PG, Cotecchia S. Amino acids of the alpha1B-adrenergic receptor involved in agonist binding: differences in docking catecholamines to receptor subtypes. Febs Letters. 399: 9-13. PMID 8980109 DOI: 10.1016/S0014-5793(96)01286-0  0.515
1997 Cotecchia S, Scheer A, Fanelli F, Costa T. Molecular mechanisms underlying the activation and regulation of the alpha 1B-adrenergic receptor. Biochemical Society Transactions. 24: 959-63. PMID 8968492 DOI: 10.1042/BST0240959  0.53
1997 Lee TW, Wise A, Cotecchia S, Milligan G. A constitutively active mutant of the alpha 1B-adrenergic receptor can cause greater agonist-dependent down-regulation of the G-proteins G9 alpha and G11 alpha than the wild-type receptor. The Biochemical Journal. 79-86. PMID 8947470 DOI: 10.1042/BJ3200079  0.606
1996 Beguin P, Beggah A, Cotecchia S, Geering K. Adrenergic, dopaminergic, and muscarinic receptor stimulation leads to PKA phosphorylation of Na-K-ATPase. The American Journal of Physiology. 270: C131-7. PMID 8772438 DOI: 10.1152/AJPCELL.1996.270.1.C131  0.429
1996 Diviani D, Lattion AL, Larbi N, Kunapuli P, Pronin A, Benovic JL, Cotecchia S. Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the alpha1B-adrenergic receptor. The Journal of Biological Chemistry. 271: 5049-58. PMID 8617782 DOI: 10.1074/Jbc.271.9.5049  0.667
1996 Scheer A, Fanelli F, Costa T, De Benedetti PG, Cotecchia S. Constitutively active mutants of the alpha 1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation. The Embo Journal. 15: 3566-3578. DOI: 10.1002/j.1460-2075.1996.tb00726.x  0.521
1995 Cotecchia S, Lattion AL, Diviani D, Cavalli A. Signalling and regulation of the alpha 1B-adrenergic receptor. Biochemical Society Transactions. 23: 121-5. PMID 7758682 DOI: 10.1042/BST0230121  0.507
1995 Diviani D, Lattion A, Cotecchia S. Effect of distinct G-protein-coupled receptor kinases on regulation of the α1B adrenergic receptor Pharmacological Research. 31: 211. DOI: 10.1016/1043-6618(95)87102-0  0.505
1995 CAVALLI A, MOSTARDINI M, COTECCHIA S. Cloning and tissue distribution of the mouse alpha1B-adrenergic receptor Pharmacological Research. 31: 192-192. DOI: 10.1016/1043-6618(95)87028-8  0.411
1995 Cotecchia S. The alpha1-adrenoceptors: Molecular mechanisms of activation and regulation Pharmacological Research. 31: 153. DOI: 10.1016/1043-6618(95)86873-9  0.341
1993 Munoz CM, Cotecchia S, Leeb-Lundberg LM. B2 kinin receptor-mediated internalization of bradykinin in DDT1 MF-2 smooth muscle cells is paralleled by sequestration of the occupied receptors. Archives of Biochemistry and Biophysics. 301: 336-44. PMID 8384832 DOI: 10.1006/ABBI.1993.1153  0.76
1993 Luttrell LM, Ostrowski J, Cotecchia S, Kendall H, Lefkowitz RJ. Antagonism of catecholamine receptor signaling by expression of cytoplasmic domains of the receptors. Science (New York, N.Y.). 259: 1453-7. PMID 8383880 DOI: 10.1126/SCIENCE.8383880  0.789
1993 Lefkowitz RJ, Cotecchia S, Samama P, Costa T. Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins. Trends in Pharmacological Sciences. 14: 303-7. PMID 8249148 DOI: 10.1016/0165-6147(93)90048-O  0.812
1993 Samama P, Cotecchia S, Costa T, Lefkowitz R. A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model. Journal of Biological Chemistry. 268: 4625-4636. DOI: 10.1016/s0021-9258(18)53442-6  0.776
1993 Blitzer R, Omri G, De Vivo M, Carty D, Premont R, Codina J, Birnbaumer L, Cotecchia S, Caron M, Lefkowitz R. Coupling of the expressed alpha 1B-adrenergic receptor to the phospholipase C pathway in Xenopus oocytes. The role of Go. Journal of Biological Chemistry. 268: 7532-7537. DOI: 10.1016/s0021-9258(18)53208-7  0.496
1992 Allen LF, Lefkowitz RJ, Caron MG, Cotecchia S. G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity. Proceedings of the National Academy of Sciences of the United States of America. 88: 11354-8. PMID 1662393 DOI: 10.1073/PNAS.88.24.11354  0.723
1992 Cotecchia S, Ostrowski J, Kjelsberg MA, Caron MG, Lefkowitz RJ. Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis. Journal of Biological Chemistry. 267: 1633-1639. DOI: 10.1016/s0021-9258(18)45992-3  0.484
1992 Kjelsberg MA, Cotecchia S, Ostrowski J, Caron MG, Lefkowitz RJ. Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation. Journal of Biological Chemistry. 267: 1430-1433. DOI: 10.1016/s0021-9258(18)45962-5  0.529
1991 Fargin A, Yamamoto K, Cotecchia S, Goldsmith PK, Spiegel AM, Lapetina EG, Caron MG, Lefkowitz RJ. Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein. Cellular Signalling. 3: 547-57. PMID 1786205 DOI: 10.1016/0898-6568(91)90031-O  0.678
1991 Lomasney JW, Cotecchia S, Lorenz W, Leung WY, Schwinn DA, Yang-Feng TL, Brownstein M, Lefkowitz RJ, Caron MG. Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. The Journal of Biological Chemistry. 266: 6365-9. PMID 1706716  0.824
1991 Lomasney JW, Cotecchia S, Lefkowitz RJ, Caron MG. Molecular biology of alpha-adrenergic receptors: implications for receptor classification and for structure-function relationships. Biochimica Et Biophysica Acta. 1095: 127-39. PMID 1657194 DOI: 10.1016/0167-4889(91)90075-9  0.825
1991 O'Malley MK, Cotecchia S, Hagen PO. Altered catecholamine receptor affinity in rabbit aortic intimal hyperplasia Journal of Surgical Research. 51: 148-153. PMID 1650865 DOI: 10.1016/0022-4804(91)90086-2  0.397
1991 Schwinn D, Page S, Cotecchia S, Caron M, Lefkowitz R. THE α1-ADRENERGIC RECEPTOR SUBTYPE COUPLES TO PHOSPHOLIPASE C Anesthesiology. 75: A629-A629. DOI: 10.1097/00000542-199109001-00628  0.734
1990 Cotecchia S, Exum S, Caron MG, Lefkowitz RJ. Regions of the alpha 1-adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function. Proceedings of the National Academy of Sciences of the United States of America. 87: 2896-900. PMID 2158097 DOI: 10.1073/PNAS.87.8.2896  0.765
1990 Yang-Feng TL, Xue F, Zhong W, Cotecchia S, Frielle T, Caron MG, Lefkowitz RJ, Francke U. Chromosomal organization of adrenergic receptor genes Proceedings of the National Academy of Sciences of the United States of America. 87: 1516-1520. PMID 2154750 DOI: 10.1073/Pnas.87.4.1516  0.792
1990 Schwinn DA, Lomasney JW, Lorenz W, Szklut PJ, Fremeau RT, Yang-Feng TL, Caron MG, Lefkowitz RJ, Cotecchia S. Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype. The Journal of Biological Chemistry. 265: 8183-9. PMID 1970822  0.834
1990 Schwinn DA, Cotecchia S, Lomasney J, Caron M, Lefkowitz RJ. MOLECULAR CLONING AND EXPRESSION OF A NEW ALPHA-1-ADRENERGIC RECEPTOR SUBTYPE Anesthesia & Analgesia. 70: S359. DOI: 10.1213/00000539-199002001-00359  0.827
1990 Cotecchia S, Kobilka BK, Daniel KW, Nolan RD, Lapetina EY, Caron MG, Lefkowitz RJ, Regan JW. Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells. Journal of Biological Chemistry. 265: 63-69. DOI: 10.1016/s0021-9258(19)40195-6  0.561
1990 COTECCHIA S, CARON M, LEFKOWITZ R. The molecular basis of adrenergic receptor function Cell Biology International Reports. 14: 34. DOI: 10.1016/0309-1651(90)90244-S  0.711
1989 Palacios JM, O'Dowd BF, Cotecchia S, Hnatowich M, Caron MG, Lefkowitz RJ. Adrenergic receptor homologies in vertebrate and invertebrate species examined by DNA hybridization. Life Sciences. 44: 2057-65. PMID 2545987 DOI: 10.1016/0024-3205(89)90352-4  0.783
1989 Fargin A, Raymond JR, Regan JW, Cotecchia S, Lefkowitz RJ, Caron MG. Effector Coupling Mechanisms of the Cloned 5-HT1A Receptor Journal of Biological Chemistry. 264: 14848-14852. DOI: 10.1016/s0021-9258(18)63778-0  0.473
1988 Lefkowitz RJ, Kobilka BK, Benovic JL, Bouvier M, Cotecchia S, Hausdorff WP, Dohlman HG, Regan JW, Caron MG. Molecular biology of adrenergic receptors. Cold Spring Harbor Symposia On Quantitative Biology. 53: 507-14. PMID 2855490 DOI: 10.1101/Sqb.1988.053.01.058  0.801
1988 Cotecchia S, Schwinn DA, Randall RR, Lefkowitz RJ, Caron MG, Kobilka BK. Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 85: 7159-63. PMID 2845398 DOI: 10.1073/Pnas.85.19.7159  0.822
1987 Leeb-Lundberg L, Cotecchia S, DeBlasi A, Caron M, Lefkowitz R. Regulation of adrenergic receptor function by phosphorylation. I. Agonist-promoted desensitization and phosphorylation of alpha 1-adrenergic receptors coupled to inositol phospholipid metabolism in DDT1 MF-2 smooth muscle cells. Journal of Biological Chemistry. 262: 3098-3105. DOI: 10.1016/s0021-9258(18)61474-7  0.544
1987 Benovic JL, Regan JW, Matsui H, Mayor F, Cotecchia S, Leeb-Lundberg LM, Caron MG, Lefkowitz RJ. Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase. Journal of Biological Chemistry. 262: 17251-17253. DOI: 10.1016/s0021-9258(18)45367-7  0.77
1986 Cruise JL, Cotecchia S, Michalopoulos G. Norepinephrine decreases EGF binding in primary rat hepatocyte cultures. Journal of Cellular Physiology. 127: 39-44. PMID 3007540 DOI: 10.1002/Jcp.1041270106  0.406
1986 Cotecchia S, Leeb-Lundberg LM, Hagen PO, Lefkowitz RJ, Caron MG. Phorbol ester effects on alpha 1-adrenoceptor binding and phosphatidylinositol metabolism in cultured vascular smooth muscle cells. Life Sciences. 37: 2389-98. PMID 3001461 DOI: 10.1016/0024-3205(85)90106-7  0.761
1986 Lomasney JW, Leeb-Lundberg LM, Cotecchia S, Regan JW, DeBernardis JF, Caron MG, Lefkowitz RJ. Mammalian alpha 1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit. Journal of Biological Chemistry. 261: 7710-7716. DOI: 10.1016/s0021-9258(19)57458-0  0.792
1985 Leeb-Lundberg LM, Cotecchia S, Lomasney JW, DeBernardis JF, Lefkowitz RJ, Caron MG. Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism. Proceedings of the National Academy of Sciences of the United States of America. 82: 5651-5. PMID 2994039 DOI: 10.1073/PNAS.82.17.5651  0.833
1983 De Blasi A, Cotecchia S, Mennini T. Selective changes of receptor binding in brain regions of aged rats. Life Sciences. 31: 335-40. PMID 6128662 DOI: 10.1016/0024-3205(82)90412-X  0.462
1982 Mennini T, Cotecchia S, Caccia S, Garattini S. Does ethyl-beta-carboline-3-carboxylate interact with mouse brain benzodiazepine receptors in vivo? The Journal of Pharmacy and Pharmacology. 34: 394-5. PMID 6124626 DOI: 10.1111/j.2042-7158.1982.tb04738.x  0.379
1982 Mennini T, Cotecchia S, Caccia S, Garattini S. Benzodiazepines: relationship between pharmacological activity in the rat and in vivo receptor binding. Pharmacology, Biochemistry, and Behavior. 16: 529-32. PMID 6122216 DOI: 10.1016/0091-3057(82)90409-9  0.365
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