Ponnal Nambi - Publications

Affiliations: 
Duke University, Durham, NC 

100 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Ullrich JW, Morris R, Bernotas RC, Travins JM, Jetter J, Unwalla R, Quinet E, Nambi P, Feingold I, Huselton C, Enroth C, Wilhelmsson A, Goos-Nilsson A, Wrobel J. Synthesis of 4-(3-biaryl)quinoline sulfones as potent liver X receptor agonists. Bioorganic & Medicinal Chemistry Letters. 20: 2903-7. PMID 20382019 DOI: 10.1016/J.Bmcl.2010.03.031  0.376
2010 Travins JM, Bernotas RC, Kaufman DH, Quinet E, Nambi P, Feingold I, Huselton C, Wilhelmsson A, Goos-Nilsson A, Wrobel J. 1-(3-Aryloxyaryl)benzimidazole sulfones are liver X receptor agonists. Bioorganic & Medicinal Chemistry Letters. 20: 526-30. PMID 20006495 DOI: 10.1016/J.Bmcl.2009.11.099  0.376
2010 Singhaus RR, Bernotas RC, Steffan R, Matelan E, Quinet E, Nambi P, Feingold I, Huselton C, Wilhelmsson A, Goos-Nilsson A, Wrobel J. 3-(3-Aryloxyaryl)imidazo[1,2-a]pyridine sulfones as liver X receptor agonists. Bioorganic & Medicinal Chemistry Letters. 20: 521-5. PMID 20005711 DOI: 10.1016/J.Bmcl.2009.11.098  0.396
2010 Hu B, Bernotas R, Unwalla R, Collini M, Quinet E, Feingold I, Goos-Nilsson A, Wilhelmsson A, Nambi P, Evans M, Wrobel J. Quinoline-3-carboxamide containing sulfones as liver X receptor (LXR) agonists with binding selectivity for LXRbeta and low blood-brain penetration. Bioorganic & Medicinal Chemistry Letters. 20: 689-93. PMID 19962892 DOI: 10.1016/J.Bmcl.2009.11.062  0.356
2010 Bernotas RC, Singhaus RR, Kaufman DH, Travins JM, Ullrich JW, Unwalla R, Quinet E, Evans M, Nambi P, Olland A, Kauppi B, Wilhelmsson A, Goos-Nilsson A, Wrobel J. 4-(3-Aryloxyaryl)quinoline sulfones are potent liver X receptor agonists Bioorganic and Medicinal Chemistry Letters. 20: 209-212. PMID 19932617 DOI: 10.1016/J.Bmcl.2009.10.132  0.382
2009 Bernotas RC, Kaufman DH, Singhaus RR, Ullrich J, Unwalla R, Quinet E, Nambi P, Wilhelmsson A, Goos-Nilsson A, Wrobel J. 4-(3-aryloxyaryl)quinoline alcohols are liver X receptor agonists. Bioorganic & Medicinal Chemistry. 17: 8086-92. PMID 19853462 DOI: 10.1016/J.Bmc.2009.10.001  0.325
2009 Hu B, Unwalla R, Collini M, Quinet E, Feingold I, Goos-Nilsson A, Wihelmsson A, Nambi P, Wrobel J. Discovery and SAR of cinnolines/quinolines as liver X receptor (LXR) agonists with binding selectivity for LXRbeta. Bioorganic & Medicinal Chemistry. 17: 3519-27. PMID 19394832 DOI: 10.1016/J.Bmc.2009.04.012  0.373
2009 Bernotas RC, Singhaus RR, Kaufman DH, Ullrich J, Fletcher H, Quinet E, Nambi P, Unwalla R, Wilhelmsson A, Goos-Nilsson A, Farnegardh M, Wrobel J. Biarylether amide quinolines as liver X receptor agonists. Bioorganic & Medicinal Chemistry. 17: 1663-70. PMID 19162487 DOI: 10.1016/J.Bmc.2008.12.048  0.396
2008 Wrobel J, Steffan R, Bowen SM, Magolda R, Matelan E, Unwalla R, Basso M, Clerin V, Gardell SJ, Nambi P, Quinet E, Reminick JI, Vlasuk GP, Wang S, Feingold I, et al. Indazole-based liver X receptor (LXR) modulators with maintained atherosclerotic lesion reduction activity but diminished stimulation of hepatic triglyceride synthesis. Journal of Medicinal Chemistry. 51: 7161-8. PMID 18973288 DOI: 10.1021/Jm800799Q  0.315
2008 DiBlasio-Smith EA, Arai M, Quinet EM, Evans MJ, Kornaga T, Basso MD, Chen L, Feingold I, Halpern AR, Liu QY, Nambi P, Savio D, Wang S, Mounts WM, Isler JA, et al. Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells. Journal of Translational Medicine. 6: 59. PMID 18925943 DOI: 10.1186/1479-5876-6-59  0.304
2008 Hu B, Quinet E, Unwalla R, Collini M, Jetter J, Dooley R, Andraka D, Nogle L, Savio D, Halpern A, Goos-Nilsson A, Wilhelmsson A, Nambi P, Wrobel J. Carboxylic acid based quinolines as liver X receptor modulators that have LXRbeta receptor binding selectivity. Bioorganic & Medicinal Chemistry Letters. 18: 54-9. PMID 18023179 DOI: 10.1016/J.Bmcl.2007.11.013  0.362
2007 Liu QY, Quinet E, Nambi P. Adipocyte fatty acid-binding protein (aP2), a newly identified LXR target gene, is induced by LXR agonists in human THP-1 cells. Molecular and Cellular Biochemistry. 302: 203-13. PMID 17396233 DOI: 10.1007/S11010-007-9442-5  0.363
2007 Hu B, Jetter J, Kaufman D, Singhaus R, Bernotas R, Unwalla R, Quinet E, Savio D, Halpern A, Basso M, Keith J, Clerin V, Chen L, Liu QY, Feingold I, ... ... Nambi P, et al. Further modification on phenyl acetic acid based quinolines as liver X receptor modulators. Bioorganic & Medicinal Chemistry. 15: 3321-33. PMID 17391964 DOI: 10.1016/J.Bmc.2007.03.013  0.338
2006 Hu B, Collini M, Unwalla R, Miller C, Singhaus R, Quinet E, Savio D, Halpern A, Basso M, Keith J, Clerin V, Chen L, Resmini C, Liu QY, Feingold I, ... ... Nambi P, et al. Discovery of phenyl acetic acid substituted quinolines as novel liver X receptor agonists for the treatment of atherosclerosis. Journal of Medicinal Chemistry. 49: 6151-4. PMID 17034119 DOI: 10.1021/Jm0609566  0.354
2006 Quinet EM, Savio DA, Halpern AR, Chen L, Schuster GU, Gustafsson JA, Basso MD, Nambi P. Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting. Molecular Pharmacology. 70: 1340-9. PMID 16825483 DOI: 10.1124/Mol.106.022608  0.349
2002 Aiyar N, Disa J, Ao Z, Xu D, Surya A, Pillarisetti K, Parameswaran N, Gupta SK, Douglas SA, Nambi P. Molecular cloning and pharmacological characterization of bovine calcitonin receptor-like receptor from bovine aortic endothelial cells. Biochemical Pharmacology. 63: 1949-59. PMID 12093471 DOI: 10.1016/S0006-2952(02)00990-5  0.485
2001 Aiyar N, Disa J, Pullen M, Nambi P. Receptor activity modifying proteins interaction with human and porcine calcitonin receptor-like receptor (CRLR) in HEK-293 cells. Molecular and Cellular Biochemistry. 224: 123-133. PMID 11693189 DOI: 10.1023/A:1011907328682  0.463
2000 Parameswaran N, Aiyar N, Wu H, Brooks DP, Nambi P, Spielman WS. Desensitization and resensitization of adrenomedullin-sensitive receptor in rat mesangial cells. European Journal of Pharmacology. 407: 205-10. PMID 11068015 DOI: 10.1016/S0014-2999(00)00656-7  0.457
2000 Disa J, Parameswaran N, Nambi P, Aiyar N. Involvement of cAMP-dependent protein kinase and pertussis toxin-sensitive G-proteins in CGRP mediated JNK activation in human neuroblastoma cell line Neuropeptides. 34: 229-233. PMID 11021985 DOI: 10.1054/Npep.2000.0810  0.448
2000 Aiyar N, Disa J, Dang K, Pronin AN, Benovic JL, Nambi P. Involvement of G protein-coupled receptor kinase-6 in desensitization of CGRP receptors. European Journal of Pharmacology. 403: 1-7. PMID 10969137 DOI: 10.1016/S0014-2999(00)00419-2  0.625
2000 Louden CS, Nambi P, Pullen MA, Thomas RA, Tierney LA, Solleveld HA, Schwartz LW. Endothelin receptor subtype distribution predisposes coronary arteries to damage American Journal of Pathology. 157: 123-134. PMID 10880383 DOI: 10.1016/S0002-9440(10)64524-5  0.347
2000 Brooks DP, Nambi P, Laping NJ, Olson BA, Pullen M, Wade CE. Renal vasopressin receptor expression and function in rats following spaceflight Journal of Applied Physiology. 88: 1316-1320. PMID 10749825 DOI: 10.1152/Jappl.2000.88.4.1316  0.419
2000 Parameswaran N, Disa J, Spielman WS, Brooks DP, Nambi P, Aiyar N. Activation of multiple mitogen-activated protein kinases by recombinant calcitonin gene-related peptide receptor. European Journal of Pharmacology. 389: 125-30. PMID 10688975 DOI: 10.1016/S0014-2999(99)00874-2  0.366
2000 Parameswaran N, Nambi P, Hall CS, Brooks DP, Spielman WS. Adrenomedullin decreases extracellular signal-regulated kinase activity through an increase in protein phosphatase-2A activity in mesangial cells. European Journal of Pharmacology. 388: 133-8. PMID 10666504 DOI: 10.1016/S0014-2999(99)00848-1  0.389
1999 Wu H, Albrightson C, Nambi P. Selective inhibition of rat mesangial cell proliferation by a synthetic peptide derived from the sequence of the C2 region of PKCβ Peptides. 20: 675-678. PMID 10477122 DOI: 10.1016/S0196-9781(99)00049-2  0.384
1999 Parameswaran N, Nambi P, Brooks DP, Spielman WS. Regulation of glomerular mesangial cell proliferation in culture by adrenomedullin. European Journal of Pharmacology. 372: 85-95. PMID 10374718 DOI: 10.1016/S0014-2999(99)00022-9  0.407
1999 Parameswaran N, Spielman WS, Brooks DP, Nambi P. SB203580 reverses adrenomedullin's effect on proliferation and apoptosis in cultured mesangial cells. European Journal of Pharmacology. 371: 75-82. PMID 10355597 DOI: 10.1016/S0014-2999(99)00146-6  0.356
1999 Parameswaran N, Spielman WS, Pullen M, Francis J, Brooks DP, Nambi P. Mechanism of adrenomedullin-stimulated hyaluronic acid release in rat mesangial cells. European Journal of Pharmacology. 370: 313-8. PMID 10334508 DOI: 10.1016/S0014-2999(99)00117-X  0.36
1998 Xiang J, Nambi P, Ohlstein EH, Elliott JD. An efficient approach to the synthesis of 1,3-diaryl-1,2,3,4-[4H]-tetrahydronaphthalene-2-carboxylic acids. Bioorganic & Medicinal Chemistry. 6: 695-700. PMID 9681135 DOI: 10.1016/S0968-0896(98)00022-4  0.301
1998 Wu H, Nambi P. Transforming growth factor-beta-mediated proliferation of renal tubular epithelial cells involves pertussis toxin-sensitive G protein-and protein kinase C-dependent pathways. Pharmacology. 57: 8-12. PMID 9670207 DOI: 10.1159/000028220  0.34
1998 Brooks DP, Depalma PD, Pullen M, Elliott JD, Ohlstein EH, Nambi P. SB 234551, a novel endothelin--A receptor antagonist, unmasks endothelin-induced renal vasodilatation in the dog. Journal of Cardiovascular Pharmacology. 31: 339-341. PMID 9595475 DOI: 10.1097/00005344-199800001-00094  0.319
1998 Douglas SA, Nambi P, Gellai M, Luengo JI, Xiang JN, Brooks DP, Ruffolo RR, Elliott JD, Ohlstein EH. Pharmacologic characterization of the novel, orally available endothelin-A - Selective antagonist SB 247083 Journal of Cardiovascular Pharmacology. 31. PMID 9595458 DOI: 10.1097/00005344-199800001-00077  0.397
1998 Laping NJ, Olson BA, Dewolf RE, Albrightson CR, Fredrickson T, King C, Chirivella M, Ziyadeh FN, Nambi P. Activation of glomerular mesangial cells by hepatocyte growth factor through tyrosine kinase and protein kinase C Biochemical Pharmacology. 55: 227-234. PMID 9448746 DOI: 10.1016/S0006-2952(97)00461-9  0.338
1997 Aiyar N, Disa J, Siemens IR, Nambi P. Differential effects of guanine nucleotides on [125I]-hCGRP(8–37) binding to porcine lung and human neuroblastoma cell membranes Neuropeptides. 31: 99-103. PMID 9574846 DOI: 10.1016/S0143-4179(97)90028-7  0.43
1997 Nambi P, Pullen M, Kincaid J, Nuthulaganti P, Aiyar N, Brooks DP, Gellai M, Kumar C. Identification and characterization of a novel endothelin receptor that binds both ETA- and ETB-selective ligands. Molecular Pharmacology. 52: 582-9. PMID 9380020 DOI: 10.1124/Mol.52.4.582  0.433
1997 Nambi P, Mattern MR, Wu HL, Pullen M, Nuthulaganti P, Hofmann GA, Kumar C. Absence of endothelin receptors and receptor mRNA in mammalian fibroblasts transformed with SV40 or ras oncogene Molecular and Cellular Biochemistry. 175: 29-35. PMID 9350030 DOI: 10.1023/A:1006827007251  0.423
1997 Pullen M, Brown G, Nambi P. Binding characteristics of [125I]TTA 386, ETA-selective antagonist. Neuropeptides. 31: 345-9. PMID 9308022 DOI: 10.1016/S0143-4179(97)90070-6  0.332
1996 Nambi P, Pullen M, Aiyar N. Correlation between guanine nucleotide effect and reversible binding property of endothelin analogs Neuropeptides. 30: 109-114. PMID 8868308 DOI: 10.1016/S0143-4179(96)90063-3  0.44
1996 Elshourbagy NA, Adamou JE, Gagnon AW, Wu H, Pullen M, Nambi P. Molecular Characterization of a Novel Human Endothelin Receptor Splice Variant Journal of Biological Chemistry. 271: 25300-25307. PMID 8810293 DOI: 10.1074/Jbc.271.41.25300  0.414
1996 Gellai M, Fletcher T, Pullen M, Nambi P. Evidence for the existence of endothelin-B receptor subtypes and their physiological roles in the rat. The American Journal of Physiology. 271: R254-61. PMID 8760228 DOI: 10.1152/AJPREGU.1996.271.1.R254  0.318
1995 Nambi P, Pullen M, Brooks DP, Gellai M. Identification of ETB Receptor Subtypes Using Linear and Truncated Analogs of ET Neuropeptides. 29: 331-336. PMID 8837960 DOI: 10.1016/0143-4179(95)90004-7  0.374
1995 Lysko PG, Elshourbagy NA, Pullen M, Nambi P. Developmental expression of endothelin receptors in cerebellar neurons differentiating in culture. Developmental Brain Research. 88: 96-101. PMID 7493411 DOI: 10.1016/0165-3806(95)00087-T  0.397
1994 Nambi P, Pullen M, Kumar C. Identification of a novel endothelin receptor in Xenopus laevis liver Neuropeptides. 26: 181-185. PMID 8208363 DOI: 10.1016/0143-4179(94)90128-7  0.399
1994 Aiyar N, Baker E, Pullen M, Nuthulaganti P, Bergsma DJ, Kumar C, Nambi P. Characterization of a functional angiotensin II receptor in Xenopus laevis heart. Pharmacology. 48: 242-9. PMID 8177910 DOI: 10.1159/000139186  0.355
1994 Nambi P, Pullen M, Slivjak MJ, Ohlstein EH, Storer B, Smith EF. Endotoxin-mediated changes in plasma endothelin concentrations, renal endothelin receptor and renal function. Pharmacology. 48: 147-56. PMID 8153142 DOI: 10.1159/000139174  0.323
1994 Gellai M, Jugus M, Fletcher T, DeWolf R, Nambi P. Reversal of postischemic acute renal failure with a selective endothelinA receptor antagonist in the rat. Journal of Clinical Investigation. 93: 900-906. PMID 8113422 DOI: 10.1172/Jci117046  0.343
1994 Aiyar N, Baker E, Nambi P, Feuerstein G, Willette R. Characterization of CGRP receptors in various regions of gerbil brain Neuropeptides. 26: 313-317. PMID 8065549 DOI: 10.1016/0143-4179(94)90116-3  0.331
1994 Ohlstein EH, Nambi P, Douglas SA, Edwards RM, Gellai M, Lago A, Leber JD, Cousins RD, Gao A, Frazee JS, Peishoff CE, Bean JW, Eggleston DS, Elshourbagy NA, Kumar C, et al. SB 209670, a rationally designed potent nonpeptide endothelin receptor antagonist Proceedings of the National Academy of Sciences of the United States of America. 91: 8052-8056. PMID 8058755 DOI: 10.1073/Pnas.91.17.8052  0.384
1994 Aiyar N, Baker E, Wu H, Nambi P, Edwards RM, Trill JJ, Ellis C, Bergsma DJ. Human AT1 receptor is a single copy gene: characterization in a stable cell line. Molecular and Cellular Biochemistry. 131: 75-86. PMID 8047068 DOI: 10.1007/Bf01075727  0.439
1994 Sung CP, Arleth AJ, Nambi P. Evidence for involvement of protein kinase c in expression of intracellular adhesion molecule-1 (ICAM-1) by human vascular endothelial cells Pharmacology. 48: 143-146. PMID 7908744 DOI: 10.1159/000139173  0.33
1994 Gellai M, DeWolf R, Pullen M, Nambi P. Distribution and functional role of renal ET receptor subtypes in normotensive and hypertensive rats Kidney International. 46: 1287-1294. PMID 7853786 DOI: 10.1038/Ki.1994.396  0.36
1993 Willette RN, Ohlstein EH, Pullen M, Sauermelch CF, Cohen A, Nambi P. Transient forebrain ischemia alters acutely endothelin receptor density and immunoreactivity in gerbil brain. Life Sciences. 52: 35-40. PMID 8417278 DOI: 10.1016/0024-3205(93)90286-C  0.337
1993 Lysko PG, Nambi P. 11 - Endothelin Receptors in Neural Systems Methods in Neurosciences. 11: 186-198. DOI: 10.1016/B978-0-12-185271-9.50016-2  0.356
1992 Yue TL, Nambi P, Wu HL, Feuerstein G. Endothelin receptor binding and cellular signal transduction in neurohybrid NG108-15 cells. Neuroscience. 44: 215-22. PMID 1663218 DOI: 10.1016/0306-4522(91)90262-M  0.355
1992 Nambi P, Pullen M, Wu H, Aiyar N, Ohlstein EH, Edwards RM. Identification of endothelin receptor subtypes in human renal cortex and medulla using subtype-selective ligands. Endocrinology. 131: 1081-1086. PMID 1324149 DOI: 10.1210/Endo.131.3.1324149  0.372
1992 Aiyar N, Griffin E, Albrightson-Winslow C, Feuerstein G, Nambi P. Homologous desensitization of calcitonin gene-related peptide response in rat glomerular mesangial cells in culture. Molecular and Cellular Biochemistry. 113: 17-23. PMID 1322492 DOI: 10.1007/Bf00230881  0.439
1991 Nambi P, Pullen M, Hsaio-Ling W, Brooks DP. Increase in renal phorbol ester receptors in rats with cyclosporine A-induced nephrotoxicity. European Journal of Pharmacology. 195: 167-169. PMID 2065710 DOI: 10.1016/0014-2999(91)90396-8  0.375
1991 DiLella AG, Ohistein E, Elshourbagy N, Bhatnagar PK, Nambi P, DeWolf WE, Caltabiano MM. Expression of human preproendothelin-1 cDNA in COS cells results in the production of mature vasoactive endothelin-1. Biochemical and Biophysical Research Communications. 175: 697-705. PMID 2018512 DOI: 10.1016/0006-291X(91)91622-J  0.36
1991 Lysko PG, Feuerstein G, Pullen M, Wu H-, Nambi P. Identification of endothelin receptors in cultured cerebellar neurons. Neuropeptides. 18: 83-86. PMID 1850120 DOI: 10.1016/0143-4179(91)90005-4  0.416
1991 Nambi P, Pullen M, Egan JW, Smith EF. Identification of cardiac endothelin binding sites in rats: downregulation of left atrial endothelin binding sites in response to myocardial infarction. Pharmacology. 43: 84-9. PMID 1663622 DOI: 10.1159/000138832  0.303
1991 Gleason MM, Wu HL, Yue TL, Feuerstein G, Nambi P. Comparison of endothelin binding and calcium mobilization in C6-BU-1 rat glioma and N18TG2 mouse neuroblastoma cells. Neuropeptides. 19: 197-204. PMID 1654531 DOI: 10.1016/0143-4179(91)90119-4  0.355
1991 Aiyar N, Nambi P, Griffin E, Bhatnagar P, Feuerstein G. Identification and Characterization of Calcitonin Gene-Related Peptide Receptors in Porcine Renal Medullary Membranes Endocrinology. 129: 965-969. PMID 1649752 DOI: 10.1210/Endo-129-2-965  0.433
1991 Brooks DP, Ohlstein EH, Contino LC, Storer B, Pullen M, Caltabiano M, Nambi P. Effect of nifedipine on cyclosporine A-induced nephrotoxicity, urinary endothelin excretion and renal endothelin receptor number European Journal of Pharmacology. 194: 115-117. PMID 1647960 DOI: 10.1016/0014-2999(91)90132-A  0.328
1991 Aiyar N, Nambi P, Crooke ST. Solubilization of Vasopressin Receptors Methods in Neurosciences. 5: 185-192. DOI: 10.1016/B978-0-12-185259-7.50016-8  0.489
1990 Nambi P, Pullen M, Feuerstein G. Identification of endothelin receptors in various regions of rat brain. Neuropeptides. 16: 195-199. PMID 2177164 DOI: 10.1016/0143-4179(90)90062-4  0.331
1990 Nambi P, Pullen M, Contino LC, Brooks DP. Upregulation of renal endothelin receptors in rats with cyclosporine A-induced nephrotoxicity European Journal of Pharmacology. 187: 113-116. PMID 2176978 DOI: 10.1016/0014-2999(90)90346-8  0.344
1990 Aiyar N, Nambi P, Crooke ST. Desensitization of vasopressin sensitive adenylate cyclase by vasopressin and phorbol esters. Cellular Signalling. 2: 153-60. PMID 2169286 DOI: 10.1016/0898-6568(90)90018-6  0.36
1990 Nambi P, Aiyar N, Wu H, Crooke ST. Possible involvement of protein kinase C and cyclic AMP-dependent protein kinase in the sodium fluoride-mediated inhibition of cyclic nucleotide accumulation in smooth muscle cells. Cellular Signalling. 2: 531-536. PMID 2081095 DOI: 10.1016/0898-6568(90)90075-L  0.401
1989 Nambi P, Mattern M, Bartus JO, Aiyar N, Crooke ST. Stimulation of intracellular topoisomerase I activity by vasopressin and thrombin. Differential regulation by pertussis toxin. The Biochemical Journal. 262: 485-9. PMID 2552999 DOI: 10.1042/BJ2620485  0.306
1989 Aiyar N, Bennett CF, Nambi P, Valinski W, Angioli M, Minnich M, Crooke ST. Solubilization of rat liver vasopressin receptors as a complex with a guanine-nucleotide-binding protein and phosphoinositide-specific phospholipase C Biochemical Journal. 261: 63-70. PMID 2549966 DOI: 10.1042/BJ2610063  0.337
1989 Nambi P, Watt R, Whitman M, Aiyar N, Moore JP, Evan GI, Crooke S. Induction of c-fos protein by activation of vasopressin receptors in smooth muscle cells. Febs Letters. 245: 61-4. PMID 2538365 DOI: 10.1016/0014-5793(89)80192-9  0.327
1989 Nambi P, Aiyar N, Whitman M, Grier CE, Crooke ST. Homologous and heterologous desensitization mediated by vasopressin in smooth muscle cells. Cellular Signalling. 1: 241-51. PMID 2534942 DOI: 10.1016/0898-6568(89)90041-7  0.378
1989 Aiyar N, Valinski W, Nambi P, Minnich M, Stassen FL, Crooke ST. Solubilization of a guanine nucleotide-sensitive form of vasopressin V2 receptors from porcine kidney. Archives of Biochemistry and Biophysics. 268: 698-706. PMID 2521556 DOI: 10.1016/0003-9861(89)90338-X  0.379
1988 Nambi P, Whitman M, Aiyar N, Crooke ST. Inhibition of formation of cyclic AMP and cyclic GMP by vasopressin in smooth-muscle cells is insensitive to pertussis toxin. Biochemical Journal. 254: 449-453. PMID 2845952 DOI: 10.1042/Bj2540449  0.347
1987 Nambi P, Whitman M, Aiyar N, Stassen F, Crooke ST. An activator of protein kinase C (phorbol dibutyrate) attenuates atrial-natriuretic-factor-stimulated cyclic GMP accumulation in smooth-muscle cells. The Biochemical Journal. 244: 481-4. PMID 2822009 DOI: 10.1042/BJ2440481  0.341
1986 Sibley DR, Jeffs RA, Daniel K, Nambi P, Lefkowitz RJ. Phorbol diester treatment promotes enhanced adenylate cyclase activity in frog erythrocytes. Archives of Biochemistry and Biophysics. 244: 373-81. PMID 3484932 DOI: 10.1016/0003-9861(86)90126-8  0.678
1986 Nambi P, Whitman MH, Schmidt DB, Heckman GD, Stassen FL, Crooke ST. Induction of functional beta-adrenergic receptors in rat aortic smooth muscle cells by sodium butyrate. Biochemical Pharmacology. 35: 3813-20. PMID 3022740 DOI: 10.1016/0006-2952(86)90669-6  0.434
1986 Stadel JM, Rebar R, Shorr RGL, Nambi P, Crooke ST. Biochemical characterization of phosphorylated beta-adrenergic receptors from catecholamine-desensitized turkey erythrocytes. Biochemistry. 25: 3719-3724. PMID 3013295 DOI: 10.1021/Bi00360A036  0.505
1986 Nambi P, Whitman M, Gessner G, Aiyar N, Crooke ST. Vasopressin-mediated inhibition of atrial natriuretic factor-stimulated cGMP accumulation in an established smooth muscle cell line Proceedings of the National Academy of Sciences of the United States of America. 83: 8492-8495. PMID 2430290 DOI: 10.1073/Pnas.83.22.8492  0.486
1986 NAMBI P, PETERS JR, SIBLEY DR, LEFKOWITZ RJ. Cell-free Desensitization of the ?-Adrenergic Receptor: Evidence that Multiple Protein Kinases Can Phosphorylate and Desensitize the Receptor Annals of the New York Academy of Sciences. 463: 122-124. DOI: 10.1111/j.1749-6632.1986.tb21519.x  0.65
1986 Nambi P, Peters JR, Sibley DR, Lefkowitz RJ. Cell-free desensitization of the β-adrenergic receptor: Evidence that multiple protein kinases can phosphorylate and desensitize the receptor Annals of the New York Academy of Sciences. 122-124. DOI: 10.1111/J.1749-6632.1986.Tb21519.X  0.667
1986 Nambi P, Whitman M, Aiyar N, Crooke ST. Vascular Vasopressin Receptors Mediate Inhibition of Atrial Natriuretic Factor (ANF)-Induced cGMP Accumulation Journal of Cardiovascular Pharmacology. 8: 1289. DOI: 10.1097/00005344-198611000-00037  0.378
1985 Nambi P, Sibley DR, Lefkowitz RJ. Sensitization of frog erythrocyte adenylate cyclase system by tumor-promoting phorbol diesters. Canadian Journal of Physiology and Pharmacology. 63: 983-6. PMID 3878225 DOI: 10.1139/Y85-162  0.64
1985 Peters J, Nambi P, Sibley D, Scanlon M. Beta Adrenergic Receptor Phosphorylation Associated with Desensitisation of Adenylate Cyclase in Avian Erythrocytes Clinical Science. 68: 24P-24P. DOI: 10.1042/CS068024PA  0.384
1985 Nambi P, Peters JR, Sibley DR, Lefkowitz RJ. Desensitization of the turkey erythrocyte beta-adrenergic receptor in a cell-free system. Evidence that multiple protein kinases can phosphorylate and desensitize the receptor. Journal of Biological Chemistry. 260: 2165-2171. DOI: 10.1016/s0021-9258(18)89532-1  0.425
1984 Sibley DR, Nambi P, Peters JR, Lefkowitz RJ. Phorbol diesters promote beta-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes. Biochemical and Biophysical Research Communications. 121: 973-9. PMID 6331437  0.686
1984 Sibley DR, Peters JR, Nambi P, Caron MG, Lefkowitz RJ. Photoaffinity labeling of turkey erythrocyte beta-adrenergic receptors: degradation of the Mr = 49,000 protein explains apparent heterogeneity. Biochemical and Biophysical Research Communications. 119: 458-64. PMID 6324763 DOI: 10.1016/S0006-291X(84)80271-5  0.698
1984 Peters JR, Nambi P, Sibley DR, Lefkowitz RJ. Enhanced adenylate cyclase activity of turkey erythrocytes following treatment with beta-adrenergic receptor antagonists. European Journal of Pharmacology. 107: 43-52. PMID 6151904 DOI: 10.1016/0014-2999(84)90089-X  0.703
1984 Nambi P, Sibley DR, Caron MG, Lefkowitz RJ. Photoaffinity labeling of beta-adrenergic receptors in mammalian tissues. Biochemical Pharmacology. 33: 3813-22. PMID 6095862 DOI: 10.1016/0006-2952(84)90045-5  0.679
1984 Shorr RGL, Kempner ES, Strohsacker MW, Nambi P, Lefkowitz RJ, Caron MG. Determination of the molecular size of frog and turkey erythrocyte .beta.-adrenergic receptors by radiation inactivation Biochemistry. 23: 747-753. DOI: 10.1021/Bi00299A025  0.621
1984 Nambi P, Sibley DR, Stadel JM, Michel T, Peters JR, Lefkowitz RJ. Cell-free desensitization of catecholamine-sensitive adenylate cyclase. Agonist- and cAMP-promoted alterations in turkey erythrocyte beta-adrenergic receptors. Journal of Biological Chemistry. 259: 4629-4633. DOI: 10.1016/s0021-9258(17)43093-6  0.626
1984 Sibley DR, Peters JR, Nambi P, Caron MG, Lefkowitz RJ. Desensitization of turkey erythrocyte adenylate cyclase. Beta-adrenergic receptor phosphorylation is correlated with attenuation of adenylate cyclase activity. Journal of Biological Chemistry. 259: 9742-9749. DOI: 10.1016/s0021-9258(17)42762-1  0.405
1984 HEALD SL, JEFFS PW, LAVIN TN, NAMBI P, LEFKOWITZ RJ, CARON MG. ChemInform Abstract: Synthesis of Iodine-125 Labeled (±)-15-(4-Azidobenzyl)carazolol: A Potent β-Adrenergic Photoaffinity Probe. Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198408322  0.482
1983 Stadel JM, Nambi P, Shorr RG, Sawyer DF, Caron MG, Lefkowitz RJ. Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 80: 3173-7. PMID 6304694 DOI: 10.1073/Pnas.80.11.3173  0.693
1983 Heald SL, Jeffs PW, Lavin TN, Nambi P, Lefkowitz RJ, Caron MG. Synthesis of iodine-125 labeled (+/-)-15-(4-azidobenzyl)carazolol: a potent beta-adrenergic photoaffinity probe. Journal of Medicinal Chemistry. 26: 832-8. PMID 6304313 DOI: 10.1021/Jm00360A009  0.646
1983 Stadel JM, Strulovici B, Nambi P, Lavin TN, Briggs MM, Caron MG, Lefkowitz RJ. Desensitization of the beta-adrenergic receptor of frog erythrocytes. Recovery and characterization of the down-regulated receptors in sequestered vesicles. Journal of Biological Chemistry. 258: 3032-3038. DOI: 10.1016/s0021-9258(18)32825-4  0.395
1982 Nambi P, Aiyar NV, Roberts AN, Sharma RK. Relationship of calcium and membrane guanylate cyclase in adrenocorticotropin-induced steroidogenesis Endocrinology. 111: 196-200. PMID 6123429 DOI: 10.1210/ENDO-111-1-196  0.328
1982 Stadel JM, Nambi P, Lavin TN, Heald SL, Caron MG, Lefkowitz RJ. Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase. Structural alterations in the beta-adrenergic receptor revealed by photoaffinity labeling. Journal of Biological Chemistry. 257: 9242-9245. DOI: 10.1016/s0021-9258(18)34055-9  0.375
1982 Lavin TN, Nambi P, Heald SL, Jeffs PW, Lefkowitz RJ, Caron MG. 125I-labeled p-azidobenzylcarazolol, a photoaffinity label for the beta-adrenergic receptor. Characterization of the ligand and photoaffinity labeling of beta 1- and beta 2-adrenergic receptors. Journal of Biological Chemistry. 257: 12332-12340. DOI: 10.1016/s0021-9258(18)33718-9  0.342
1979 Nambi P, Drummond GI. Catecholamine and guanine nucleotide activation of skeletal muscle adenylate cyclase. Biochimica Et Biophysica Acta. 583: 287-94. PMID 36171  0.325
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