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Timir Tripathi, Ph.D. - Publications

Affiliations: 
2004-2009 Biophysics All India Institute Of Medical Science, New Delhi 
 2005-2009 Molecular and Structural Biology Division CSIR - Central Drug Research Institute, Lucknow 
Area:
• Structure, dynamics, and interactions of proteins • Protein folding/misfolding/aggregation • Intrinsically disordered proteins/protein frustration/fuzzy complexes • Neurodegenerative diseases • Nuclear-cytoplasmic transport • Drug discovery for neglecte
Website:
http://ttripathi.webs.com/
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chetri PB, Shukla R, Tripathi T. Identification and characterization of cytosolic malate dehydrogenase from the liver fluke Fasciola gigantica. Scientific Reports. 10: 13372. PMID 32770017 DOI: 10.1038/S41598-020-70202-Y  0.444
2020 Kalita J, Shukla H, Tripathi T. Engineering glutathione S-transferase with a point mutation at conserved F136 residue increases the xenobiotic-metabolizing activity. International Journal of Biological Macromolecules. 163: 1117-1126. PMID 32663558 DOI: 10.1016/J.Ijbiomac.2020.07.073  0.38
2020 Shukla R, Shukla H, Tripathi T. Structure-based discovery of phenyl-diketo acids derivatives as malate synthase inhibitors. Journal of Biomolecular Structure & Dynamics. 1-14. PMID 32306850 DOI: 10.1080/07391102.2020.1758787  0.362
2020 Tripathi T, Chetri PB. Potent Inhibitors of Thioredoxin Glutathione Reductase: Grail of Anti-Schistosome Drug within Reach? Acs Infectious Diseases. 6: 893-895. PMID 32159329 DOI: 10.1021/Acsinfecdis.0C00072  0.302
2020 Das KC, Kalita P, Tripathi T. Genome-wide identification and characterization of eukaryotic protein kinases. Frontiers in Bioscience. 25: 1787-1827. DOI: 10.2741/4878  0.3
2019 Mputhia Z, Hone E, Tripathi T, Sargeant T, Martins R, Bharadwaj P. Autophagy Modulation as a Treatment of Amyloid Diseases. Molecules (Basel, Switzerland). 24. PMID 31527516 DOI: 10.3390/Molecules24183372  0.319
2019 Kalita P, Shukla H, Das KC, Tripathi T. Conserved Arg451 residue is critical for maintaining the stability and activity of thioredoxin glutathione reductase. Archives of Biochemistry and Biophysics. 108098. PMID 31494118 DOI: 10.1016/J.Abb.2019.108098  0.412
2019 Gupta S, Shukla H, Kumar A, Shukla R, Kumari R, Tripathi T, Singh RK, Anupurba S. Mycobacterium tuberculosis nucleoside diphosphate kinase shows interaction with putative ATP Binding Cassette (ABC) transporter, Rv1273c. Journal of Biomolecular Structure & Dynamics. 1-14. PMID 30898047 DOI: 10.1080/07391102.2019.1595150  0.41
2019 Chetri PB, Shukla R, Tripathi T. Identification and characterization of glyceraldehyde 3-phosphate dehydrogenase from Fasciola gigantica. Parasitology Research. PMID 30706165 DOI: 10.1007/S00436-019-06225-W  0.455
2019 Namdev P, Lyngdoh DL, Dar HY, Chaurasiya SK, Srivastava R, Tripathi T, Anupam R. Intrinsically Disordered HTLV-1 p30 protein: Experimental and Computational Evidence. Aids Research and Human Retroviruses. PMID 30618266 DOI: 10.1089/Aid.2018.0196  0.307
2018 Sonkar A, Shukla H, Shukla R, Kalita J, Tripathi T. Unfolding of Acinetobacter baumannii MurA proceeds through a metastable intermediate: A combined spectroscopic and computational investigation. International Journal of Biological Macromolecules. 126: 941-951. PMID 30562518 DOI: 10.1016/J.Ijbiomac.2018.12.124  0.374
2018 Suttiprapa S, Sotillo J, Smout M, Suyapoh W, Chaiyadet S, Tripathi T, Laha T, Loukas A. Opisthorchis viverrini proteome and host-parasite interactions Advances in Parasitology. 102: 45-72. PMID 30442310 DOI: 10.1016/Bs.Apar.2018.06.002  0.336
2018 Rajendran V, Shukla R, Shukla H, Tripathi T. Structure-function studies of the asparaginyl tRNA synthetase from Understanding the role of catalytic and non-catalytic domains. The Biochemical Journal. PMID 30287492 DOI: 10.1042/Bcj20180700  0.415
2018 Shukla R, Shukla H, Tripathi T. Structural and energetic understanding of novel natural inhibitors of Mycobacterium tuberculosis malate synthase. Journal of Cellular Biochemistry. PMID 30206985 DOI: 10.1002/Jcb.27538  0.37
2018 Kalita P, Shukla H, Gadhave K, Giri R, Tripathi T. Role of the glutaredoxin domain and FAD in the stabilization of thioredoxin glutathione reductase. Archives of Biochemistry and Biophysics. 656: 38-45. PMID 30205085 DOI: 10.1016/J.Abb.2018.09.002  0.393
2018 Kalita J, Shukla R, Tripathi T. Structural basis of urea-induced unfolding of Fasciola gigantica glutathione S-transferase. Journal of Cellular Physiology. PMID 30192010 DOI: 10.1002/Jcp.27253  0.458
2018 Dhasmana D, Singh A, Shukla R, Tripathi T, Garg N. Targeting Nucleotide Binding Domain of Multidrug Resistance-associated Protein-1 (MRP1) for the Reversal of Multi Drug Resistance in Cancer. Scientific Reports. 8: 11973. PMID 30097643 DOI: 10.1038/S41598-018-30420-X  0.361
2018 Shukla H, Khan SR, Shukla R, Krishnan MY, Akhtar MS, Tripathi T. Alternate pathway to ascorbate induced inhibition of Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 111: 161-169. PMID 30029903 DOI: 10.1016/J.Tube.2018.06.013  0.549
2018 Shav-Tal Y, Tripathi T. Yeast and Human Nuclear Pore Complexes: Not So Similar After All. Trends in Cell Biology. 28: 589-591. PMID 29941187 DOI: 10.1016/J.Tcb.2018.06.004  0.311
2018 Kalita P, Shukla H, Shukla R, Tripathi T. Biochemical and thermodynamic comparison of the selenocysteine containing and non-containing thioredoxin glutathione reductase of Fasciola gigantica. Biochimica Et Biophysica Acta. PMID 29526505 DOI: 10.1016/J.Bbagen.2018.03.007  0.474
2018 Shukla R, Shukla H, Tripathi T. Activity loss by H46A mutation in Mycobacterium tuberculosis isocitrate lyase is due to decrease in structural plasticity and collective motions of the active site. Tuberculosis (Edinburgh, Scotland). 108: 143-150. PMID 29523315 DOI: 10.1016/J.Tube.2017.11.013  0.395
2018 Rajendran V, Kalita P, Shukla H, Kumar A, Tripathi T. Aminoacyl-tRNA synthetases: Structure, function, and drug discovery. International Journal of Biological Macromolecules. PMID 29305884 DOI: 10.1016/J.Ijbiomac.2017.12.157  0.394
2017 Kalita J, Shukla R, Shukla H, Gadhave K, Giri R, Tripathi T. Comprehensive analysis of the catalytic and structural properties of a mu-class glutathione s-transferase from Fasciola gigantica. Scientific Reports. 7: 17547. PMID 29235505 DOI: 10.1038/S41598-017-17678-3  0.472
2017 Shukla R, Shukla H, Kalita P, Tripathi T. Structural insights into natural compounds as inhibitors of Fasciola gigantica thioredoxin glutathione reductase. Journal of Cellular Biochemistry. PMID 29052925 DOI: 10.1002/Jcb.26444  0.395
2017 Vijayakumar R, Tripathi T. Soluble expression and purification of a full-length asparaginyl tRNA synthetase from Fasciola gigantica. Protein Expression and Purification. 143: 9-13. PMID 29031680 DOI: 10.1016/J.Pep.2017.10.009  0.371
2017 Shukla R, Chetri PB, Sonkar A, Pakharukova MY, Mordvinov VA, Tripathi T. Identification of novel natural inhibitors of Opisthorchis felineus cytochrome P450 using structure-based screening and molecular dynamic simulation. Journal of Biomolecular Structure & Dynamics. 1-103. PMID 29029597 DOI: 10.1080/07391102.2017.1392897  0.368
2017 Shukla R, Shukla H, Kalita P, Sonkar A, Pandey T, Singh DB, Kumar A, Tripathi T. Identification of potential inhibitors of Fasciola gigantica thioredoxin1: Computational screening, molecular dynamics simulation and binding free energy studies. Journal of Biomolecular Structure & Dynamics. 1-68. PMID 28627969 DOI: 10.1080/07391102.2017.1344141  0.367
2017 Shukla H, Shukla R, Sonkar A, Tripathi T. Alterations in conformational topology and interaction dynamics caused by L418A mutation leads to activity loss of Mycobacterium tuberculosis isocitrate lyase. Biochemical and Biophysical Research Communications. 490: 276-282. PMID 28610921 DOI: 10.1016/J.Bbrc.2017.06.036  0.395
2017 Shukla R, Shukla H, Sonkar A, Pandey T, Tripathi T. Structure-Based Screening And Molecular Dynamics Simulations Offer Novel Natural Compounds As Potential Inhibitors Of Mycobacterium Tuberculosis Isocitrate Lyase. Journal of Biomolecular Structure & Dynamics. 1-106. PMID 28605994 DOI: 10.1080/07391102.2017.1341337  0.373
2017 Shukla H, Kumar R, Sonkar A, Mitra K, Akhtar MS, Tripathi T. Salt-regulated reversible fibrillation of Mycobacterium tuberculosis isocitrate lyase: Concurrent restoration of structure and activity. International Journal of Biological Macromolecules. PMID 28591590 DOI: 10.1016/J.Ijbiomac.2017.06.008  0.624
2017 Shukla H, Shukla R, Sonkar A, Pandey T, Tripathi T. Distant Phe345 mutation compromises the stability and activity of Mycobacterium tuberculosis isocitrate lyase by modulating its structural flexibility. Scientific Reports. 7: 1058. PMID 28432345 DOI: 10.1038/S41598-017-01235-Z  0.431
2017 Sonkar A, Shukla H, Shukla R, Kalita J, Pandey T, Tripathi T. UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) of Acinetobacter baumannii (AbMurA): Structural and functional properties. International Journal of Biological Macromolecules. PMID 28064057 DOI: 10.1016/J.Ijbiomac.2016.12.082  0.396
2017 Tripathi T, Suttiprapa S, Sripa B. Unusual thiol-based redox metabolism of parasitic flukes. Parasitology International. 66: 390-395. PMID 27238582 DOI: 10.1016/J.Parint.2016.05.013  0.339
2016 Pandey T, Shukla R, Shukla H, Sonkar A, Tripathi T, Singh AK. A combined biochemical and computational studies of the rho-class glutathione s-transferase sll1545 of Synechocystis PCC 6803. International Journal of Biological Macromolecules. PMID 27760379 DOI: 10.1016/J.Ijbiomac.2016.10.040  0.363
2016 Bharati AP, Singh N, Kumar V, Kashif M, Singh AK, Singh P, Singh SK, Siddiqi MI, Tripathi T, Akhtar MS. The mRNA capping enzyme of Saccharomyces cerevisiae has dual specificity to interact with CTD of RNA Polymerase II. Scientific Reports. 6: 31294. PMID 27503426 DOI: 10.1038/Srep31294  0.557
2016 Nisha CM, Kumar A, Nair P, Gupta N, Silakari C, Tripathi T, Kumar A. Molecular Docking and In Silico ADMET Study Reveals Acylguanidine 7a as a Potential Inhibitor of β-Secretase. Advances in Bioinformatics. 2016: 9258578. PMID 27190510 DOI: 10.1155/2016/9258578  0.332
2016 Gupta A, Sripa B, Tripathi T. Purification and characterization of two-domain glutaredoxin in the parasitic helminth Fasciola gigantica. Parasitology International. PMID 27189489 DOI: 10.1016/J.Parint.2016.05.005  0.407
2016 Gupta A, Kesherwani M, Velmurugan D, Tripathi T. Fasciola gigantica thioredoxin glutathione reductase: Biochemical properties and structural modeling. International Journal of Biological Macromolecules. PMID 27112978 DOI: 10.1016/J.Ijbiomac.2016.04.063  0.392
2015 Chhetri G, Kalita P, Tripathi T. An efficient protocol to enhance recombinant protein expression using ethanol in Escherichia coli. Methodsx. 2: 385-91. PMID 26629417 DOI: 10.1016/J.Mex.2015.09.005  0.306
2015 Gupta A, Pandey T, Kumar B, Tripathi T. Preferential regeneration of thioredoxin from parasitic flatworm Fasciola gigantica using glutathione system. International Journal of Biological Macromolecules. PMID 26408792 DOI: 10.1016/J.Ijbiomac.2015.09.035  0.322
2015 Pandey T, Singh SK, Chhetri G, Tripathi T, Singh AK. Characterization of a Highly pH Stable Chi-Class Glutathione S-Transferase from Synechocystis PCC 6803. Plos One. 10: e0126811. PMID 25965384 DOI: 10.1371/Journal.Pone.0126811  0.441
2015 Pandey T, Chhetri G, Chinta R, Kumar B, Singh DB, Tripathi T, Singh AK. Functional classification and biochemical characterization of a novel rho class glutathione S-transferase in Synechocystis PCC 6803. Febs Open Bio. 5: 1-7. PMID 25685659 DOI: 10.1016/J.Fob.2014.11.006  0.312
2015 Chhetri G, Ghosh A, Chinta R, Akhtar S, Tripathi T. Cloning, soluble expression, and purification of the RNA polymerase II subunit RPB5 from Saccharomyces cerevisiae. Bioengineered. 6: 62-6. PMID 25551420 DOI: 10.1080/21655979.2014.1002301  0.337
2015 Chhetri G, Pandey T, Kumar B, Akhtar MS, Tripathi T. Recombinant expression, purification and preliminary characterization of the mRNA export factor MEX67 of Saccharomyces cerevisiae. Protein Expression and Purification. 107: 56-61. PMID 25462802 DOI: 10.1016/J.Pep.2014.11.011  0.587
2014 Yogavel M, Tripathi T, Gupta A, Banday MM, Rahlfs S, Becker K, Belrhali H, Sharma A. Atomic resolution crystal structure of glutaredoxin 1 from Plasmodium falciparum and comparison with other glutaredoxins. Acta Crystallographica. Section D, Biological Crystallography. 70: 91-100. PMID 24419382 DOI: 10.1107/S1399004713025285  0.392
2010 Tripathi T, Röseler A, Rahlfs S, Becker K, Bhakuni V. Conformational stability and energetics of Plasmodium falciparum glutaredoxin. Biochimie. 92: 284-91. PMID 20006670 DOI: 10.1016/J.Biochi.2009.12.003  0.664
2009 Tripathi T, Na BK, Sohn WM, Becker K, Bhakuni V. Structural, functional and unfolding characteristics of glutathione S-transferase of Plasmodium vivax. Archives of Biochemistry and Biophysics. 487: 115-22. PMID 19467220 DOI: 10.1016/J.Abb.2009.05.011  0.69
2008 Tripathi T, Rahlfs S, Becker K, Bhakuni V. Structural and stability characteristics of a monothiol glutaredoxin: glutaredoxin-like protein 1 from Plasmodium falciparum. Biochimica Et Biophysica Acta. 1784: 946-52. PMID 18452722 DOI: 10.1016/J.Bbapap.2008.03.012  0.683
2007 Tripathi T, Rahlfs S, Becker K, Bhakuni V. Glutathione mediated regulation of oligomeric structure and functional activity of Plasmodium falciparum glutathione S-transferase. Bmc Structural Biology. 7: 67. PMID 17941979 DOI: 10.1186/1472-6807-7-67  0.676
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