| Year |
Citation |
Score |
| 2023 |
Borgonetti V, Cruz B, Vozella V, Khom S, Steinman MQ, Bullard R, D'Ambrosio S, Oleata CS, Vlkolinsky R, Bajo M, Zorrilla EP, Kirson D, Roberto M. IL-18 Signaling in the Rat Central Amygdala Is Disrupted in a Comorbid Model of Post-Traumatic Stress and Alcohol Use Disorder. Cells. 12. PMID 37566022 DOI: 10.3390/cells12151943 |
0.786 |
|
| 2023 |
Khom S, Borgonetti V, Vozella V, Kirson D, Rodriguez L, Gandhi P, Bianchi PC, Snyder A, Vlkolinsky R, Bajo M, Oleata CS, Ciccocioppo R, Roberto M. Glucocorticoid receptors regulate central amygdala GABAergic synapses in Marchigian-Sardinian alcohol-preferring rats. Neurobiology of Stress. 25: 100547. PMID 37547774 DOI: 10.1016/j.ynstr.2023.100547 |
0.817 |
|
| 2023 |
Chuong V, Farokhnia M, Khom S, Pince CL, Elvig SK, Vlkolinsky R, Marchette RC, Koob GF, Roberto M, Vendruscolo LF, Leggio L. The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates central GABA neurotransmission. Jci Insight. PMID 37192005 DOI: 10.1172/jci.insight.170671 |
0.661 |
|
| 2022 |
Rodriguez L, Kirson D, Wolfe SA, Patel RR, Varodayan FP, Snyder AE, Gandhi PJ, Khom S, Vlkolinsky R, Bajo M, Roberto M. Alcohol Dependence Induces CRF Sensitivity in Female Central Amygdala GABA Synapses. International Journal of Molecular Sciences. 23. PMID 35887190 DOI: 10.3390/ijms23147842 |
0.792 |
|
| 2022 |
Varodayan FP, Patel RR, Matzeu A, Wolfe SA, Curley DE, Khom S, Gandhi PJ, Rodriguez L, Bajo M, D'Ambrosio S, Sun H, Kerr TM, Gonzales RA, Leggio L, Natividad LA, et al. The Amygdala Noradrenergic System Is Compromised With Alcohol Use Disorder. Biological Psychiatry. PMID 35430085 DOI: 10.1016/j.biopsych.2022.02.006 |
0.766 |
|
| 2021 |
Khom S, Nguyen JD, Vandewater SA, Grant Y, Roberto M, Taffe MA. Self-Administration of Entactogen Psychostimulants Dysregulates Gamma-Aminobutyric Acid (GABA) and Kappa Opioid Receptor Signaling in the Central Nucleus of the Amygdala of Female Wistar Rats. Frontiers in Behavioral Neuroscience. 15: 780500. PMID 34975428 DOI: 10.3389/fnbeh.2021.780500 |
0.547 |
|
| 2021 |
Kirson D, Khom S, Rodriguez L, Wolfe SA, Varodayan FP, Gandhi PJ, Patel RR, Vlkolinsky R, Bajo M, Roberto M. Sex Differences in Acute Alcohol Sensitivity of Naïve and Alcohol Dependent Central Amygdala GABA Synapses. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 33912894 DOI: 10.1093/alcalc/agab034 |
0.789 |
|
| 2020 |
Steinman MQ, Kirson D, Wolfe SA, Khom S, D'Ambrosio SR, Spierling Bagsic SR, Bajo M, Vlkolinský R, Hoang NK, Singhal A, Sureshchandra S, Oleata CS, Messaoudi I, Zorrilla EP, Roberto M. Importance of sex and trauma context on circulating cytokines and amygdalar GABAergic signaling in a comorbid model of posttraumatic stress and alcohol use disorders. Molecular Psychiatry. PMID 33087855 DOI: 10.1038/s41380-020-00920-2 |
0.772 |
|
| 2020 |
Demoret RM, Baker MA, Ohtawa M, Chen S, Lam CC, Khom S, Roberto M, Forli S, Houk KN, Shenvi RA. Synthetic, Mechanistic and Biological Interrogation of Ginkgo biloba Chemical Space en route to (-)-Bilobalide. Journal of the American Chemical Society. PMID 32991152 DOI: 10.1021/jacs.0c08231 |
0.401 |
|
| 2020 |
Khom S, Wolfe SA, Patel RR, Kirson D, Hedges DM, Varodayan FP, Bajo M, Roberto M. Alcohol Dependence and Withdrawal Impair Serotonergic Regulation of GABA Transmission in the Rat Central Nucleus of the Amygdala. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 40: 6842-6853. PMID 32769108 DOI: 10.1523/Jneurosci.0733-20.2020 |
0.799 |
|
| 2020 |
Warden AS, Wolfe SA, Khom S, Varodayan FP, Patel RR, Steinman MQ, Bajo M, Montgomery SE, Vlkolinsky R, Nadav T, Polis I, Roberts AJ, Mayfield RD, Harris RA, Roberto M. Microglia Control Escalation of Drinking in Alcohol-Dependent Mice: Genomic and Synaptic Drivers. Biological Psychiatry. PMID 32680583 DOI: 10.1016/J.Biopsych.2020.05.011 |
0.788 |
|
| 2020 |
Khom S, Steinkellner T, Hnasko TS, Roberto M. Alcohol dependence potentiates substance P/neurokinin-1 receptor signaling in the rat central nucleus of amygdala. Science Advances. 6: eaaz1050. PMID 32206720 DOI: 10.1126/Sciadv.Aaz1050 |
0.6 |
|
| 2020 |
Roberto M, Kirson D, Khom S. The Role of the Central Amygdala in Alcohol Dependence. Cold Spring Harbor Perspectives in Medicine. PMID 31988201 DOI: 10.1101/Cshperspect.A039339 |
0.673 |
|
| 2019 |
Roberts AJ, Khom S, Bajo M, Vlkolinsky R, Polis I, Cates-Gatto C, Roberto M, Gruol DL. Increased IL-6 expression in astrocytes is associated with emotionality, alterations in central amygdala GABAergic transmission, and excitability during alcohol withdrawal. Brain, Behavior, and Immunity. PMID 31437534 DOI: 10.1016/J.Bbi.2019.08.185 |
0.557 |
|
| 2019 |
Suárez J, Khom S, Alén F, Natividad LA, Varodayan FP, Patel RR, Kirson D, Arco R, Ballesta A, Bajo M, Rubio L, Martin-Fardon R, Rodríguez de Fonseca F, Roberto M. Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala. Addiction Biology. e12813. PMID 31339221 DOI: 10.1111/Adb.12813 |
0.812 |
|
| 2019 |
Tunstall BJ, Kirson D, Zallar LJ, McConnell SA, Vendruscolo JCM, Ho CP, Oleata CS, Khom S, Manning M, Lee MR, Leggio L, Koob GF, Roberto M, Vendruscolo LF. Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala. Plos Biology. 17: e2006421. PMID 30990816 DOI: 10.1371/Journal.Pbio.2006421 |
0.683 |
|
| 2019 |
Patel RR, Khom S, Steinman MQ, Varodayan FP, Kiosses WB, Hedges DM, Vlkolinsky R, Nadav T, Polis I, Bajo M, Roberts AJ, Roberto M. IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala. Brain, Behavior, and Immunity. 75: 208-219. PMID 30791967 DOI: 10.1016/J.Bbi.2018.10.009 |
0.748 |
|
| 2018 |
Stadler M, Monticelli S, Seidel T, Luger D, Salzer I, Boehm S, Holzer W, Schwarzer C, Urban E, Khom S, Langer T, Pace V, Hering S. Design, synthesis and pharmacological evaluation of novel β2/3 subunit-selective γ-Aminobutyric Acid Type A (GABAA) receptor modulators. Journal of Medicinal Chemistry. PMID 30289721 DOI: 10.1021/acs.jmedchem.8b00859 |
0.555 |
|
| 2018 |
Varodayan FP, Khom S, Patel RR, Steinman MQ, Hedges DM, Oleata CS, Homanics GE, Roberto M, Bajo M. Role of TLR4 in the Modulation of Central Amygdala GABA Transmission by CRF Following Restraint Stress. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 29309503 DOI: 10.1093/Alcalc/Agx114 |
0.741 |
|
| 2017 |
Varodayan FP, Correia D, Kirson D, Khom S, Oleata CS, Luu G, Schweitzer P, Roberto M. CRF modulates glutamate transmission in the central amygdala of naïve and ethanol-dependent rats. Neuropharmacology. PMID 28807676 DOI: 10.1016/J.Neuropharm.2017.08.009 |
0.607 |
|
| 2017 |
Nguyen JD, Kirson D, Grant Y, Varodayan FP, Khom S, Patel R, Hedges DM, Roberto M, Taffe MA. Kappa Opioid Receptor Signaling Contributes to Re‐escalation of Oxycodone Self‐administration Under Extended Access Conditions The Faseb Journal. 31. DOI: 10.1096/Fasebj.31.1_Supplement.985.1 |
0.422 |
|
| 2017 |
Khom S, Rice K, Roberto M. Alcohol dependence alters substance P/neurokinin 1 receptor signaling in the central nucleus of the amygdala Alcohol. 60: 228. DOI: 10.1016/J.Alcohol.2017.02.288 |
0.639 |
|
| 2017 |
Bajo M, Steinman MQ, Varodayan FP, Khom S, Patel RR, Hedges DM, Herman MA, Montgomery SE, Nadav T, Steiner N, Mandyam CD, Roberts AJ, Roberto M. Chronic ethanol-induced immune responses in the mouse central amygdala: Focus on glia and IL-1 system Alcohol. 60: 225. DOI: 10.1016/J.Alcohol.2017.02.278 |
0.754 |
|
| 2016 |
Khom S, Hintersteiner J, Luger D, Haider M, Pototschnig G, Mihovilovic MD, Schwarzer C, Hering S. Analysis of β-Subunit-dependent GABAA Receptor Modulation and Behavioral Effects of Valerenic Acid Derivatives. The Journal of Pharmacology and Experimental Therapeutics. 357: 580-90. PMID 27190170 DOI: 10.1124/jpet.116.232983 |
0.502 |
|
| 2015 |
Luger D, Poli G, Wieder M, Stadler M, Ke S, Ernst M, Hohaus A, Linder T, Seidel T, Langer T, Khom S, Hering S. Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis. British Journal of Pharmacology. PMID 26375408 DOI: 10.1111/bph.13329 |
0.507 |
|
| 2015 |
Wimmer L, Schönbauer D, Pakfeifer P, Schöffmann A, Khom S, Hering S, Mihovilovic MD. Developing piperine towards TRPV1 and GABAA receptor ligands--synthesis of piperine analogs via Heck-coupling of conjugated dienes. Organic & Biomolecular Chemistry. 13: 990-4. PMID 25438036 DOI: 10.1039/c4ob02242d |
0.51 |
|
| 2014 |
Strommer B, Khom S, Kastenberger I, Cicek SS, Stuppner H, Schwarzer C, Hering S. A cycloartane glycoside derived from Actaea racemosa L. modulates GABAA receptors and induces pronounced sedation in mice. The Journal of Pharmacology and Experimental Therapeutics. 351: 234-42. PMID 25161170 DOI: 10.1124/jpet.114.218024 |
0.564 |
|
| 2014 |
Schöffmann A, Wimmer L, Goldmann D, Khom S, Hintersteiner J, Baburin I, Schwarz T, Hintersteininger M, Pakfeifer P, Oufir M, Hamburger M, Erker T, Ecker GF, Mihovilovic MD, Hering S. Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives. Journal of Medicinal Chemistry. 57: 5602-19. PMID 24905252 DOI: 10.1021/Jm5002277 |
0.494 |
|
| 2014 |
Hintersteiner J, Haider M, Luger D, Schwarzer C, Reznicek G, Jäger W, Khom S, Mihovilovic MD, Hering S. Esters of valerenic acid as potential prodrugs. European Journal of Pharmacology. 735: 123-31. PMID 24680924 DOI: 10.1016/j.ejphar.2014.03.019 |
0.579 |
|
| 2013 |
Khom S, Strommer B, Schöffmann A, Hintersteiner J, Baburin I, Erker T, Schwarz T, Schwarzer C, Zaugg J, Hamburger M, Hering S. GABAA receptor modulation by piperine and a non-TRPV1 activating derivative. Biochemical Pharmacology. 85: 1827-36. PMID 23623790 DOI: 10.1016/J.Bcp.2013.04.017 |
0.584 |
|
| 2012 |
Singhuber J, Baburin I, Khom S, Zehl M, Urban E, Hering S, Kopp B. GABA(A) receptor modulators from the Chinese herbal drug Junci Medulla--the pith of Juncus effusus. Planta Medica. 78: 455-8. PMID 22271080 DOI: 10.1055/s-0031-1298174 |
0.58 |
|
| 2011 |
Zaugg J, Khom S, Eigenmann D, Baburin I, Hamburger M, Hering S. Identification and characterization of GABA(A) receptor modulatory diterpenes from Biota orientalis that decrease locomotor activity in mice. Journal of Natural Products. 74: 1764-72. PMID 21793559 DOI: 10.1021/np200317p |
0.544 |
|
| 2010 |
Cicek SS, Khom S, Taferner B, Hering S, Stuppner H. Bioactivity-guided isolation of GABA(A) receptor modulating constituents from the rhizomes of Actaea racemosa. Journal of Natural Products. 73: 2024-8. PMID 21082802 DOI: 10.1021/np100479w |
0.572 |
|
| 2010 |
Khom S, Strommer B, Ramharter J, Schwarz T, Schwarzer C, Erker T, Ecker GF, Mulzer J, Hering S. Valerenic acid derivatives as novel subunit-selective GABAA receptor ligands - in vitro and in vivo characterization. British Journal of Pharmacology. 161: 65-78. PMID 20718740 DOI: 10.1111/J.1476-5381.2010.00865.X |
0.578 |
|
| 2009 |
Baburin I, Khom S, Timin E, Hohaus A, Sieghart W, Hering S. Benzodiazepines modulate GABAA receptors by reducing a gamma-subunit-mediated inhibition of GABA sensitivity Bmc Pharmacology. 9: A23. DOI: 10.1186/1471-2210-9-S2-A23 |
0.567 |
|
| 2008 |
Baburin I, Khom S, Timin E, Hohaus A, Sieghart W, Hering S. Estimating the efficiency of benzodiazepines on GABA(A) receptors comprising gamma1 or gamma2 subunits. British Journal of Pharmacology. 155: 424-33. PMID 18604239 DOI: 10.1038/bjp.2008.271 |
0.569 |
|
| 2008 |
Kim HJ, Baburin I, Khom S, Hering S, Hamburger M. HPLC-based activity profiling approach for the discovery of GABAA receptor ligands using an automated two microelectrode voltage clamp assay on Xenopus oocytes. Planta Medica. 74: 521-6. PMID 18543148 DOI: 10.1055/s-2008-1074491 |
0.552 |
|
| 2008 |
Trauner G, Khom S, Baburin I, Benedek B, Hering S, Kopp B. Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid. Planta Medica. 74: 19-24. PMID 18095218 DOI: 10.1055/s-2007-993761 |
0.533 |
|
| 2007 |
Khom S, Baburin I, Timin E, Hohaus A, Trauner G, Kopp B, Hering S. Valerenic acid potentiates and inhibits GABA(A) receptors: molecular mechanism and subunit specificity. Neuropharmacology. 53: 178-87. PMID 17585957 DOI: 10.1016/j.neuropharm.2007.04.018 |
0.551 |
|
| 2007 |
Kim H, Khom S, Baburin I, Hering S, Hamburger M. HPLC-based activity profiling of plant and fungal extracts for GABAA receptor ligands using a functional assay with Xenopus oocytes Planta Medica. 73. DOI: 10.1055/s-2007-986720 |
0.487 |
|
| 2006 |
Khom S, Baburin I, Timin EN, Hohaus A, Sieghart W, Hering S. Pharmacological properties of GABAA receptors containing gamma1 subunits. Molecular Pharmacology. 69: 640-9. PMID 16272224 DOI: 10.1124/mol.105.017236 |
0.545 |
|
| 2006 |
Brattström A, Baburin I, Khom S, Hering S, Koetter U. Valerian extract modulates the GABAA-action on its receptors Planta Medica. 72. DOI: 10.1055/S-2006-950024 |
0.525 |
|
| 2006 |
Trauner G, Khom S, Benedek B, Hering S, Kopp B. Identification of GABAA-modulators obtained from Valeriana officinalis L Planta Medica. 72. DOI: 10.1055/S-2006-949848 |
0.457 |
|
| 0 |
Khom S. . PMID 32206720 |
0.38 |
|
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