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Yongna Xing, Ph.D. - Publications

Affiliations: 
Oncology University of Wisconsin, Madison, Madison, WI 
Website:
http://mcardle.oncology.wisc.edu/xing/
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54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Konovalov KA, Wu CG, Qiu Y, Balakrishnan VK, Parihar PS, O'Connor MS, Xing Y, Huang X. Disease mutations and phosphorylation alter the allosteric pathways involved in autoinhibition of protein phosphatase 2A. The Journal of Chemical Physics. 158. PMID 37260014 DOI: 10.1063/5.0150272  0.313
2022 Li Y, Balakrishnan VK, Rowse M, Wu CG, Bravos AP, Yadav VK, Ivarsson Y, Strack S, Novikova IV, Xing Y. Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition. Elife. 11. PMID 35924897 DOI: 10.7554/eLife.79736  0.358
2021 Kim SH, Wu CG, Jia W, Xing Y, Tibbetts RS. Roles of constitutive and signal-dependent protein phosphatase 2A docking motifs in burst-attenuation of the cyclic AMP response element binding protein. The Journal of Biological Chemistry. 100908. PMID 34171357 DOI: 10.1016/j.jbc.2021.100908  0.32
2021 Kim SH, Wu CG, Jia W, Xing Y, Tibbetts RS. Roles of constitutive and signal-dependent protein phosphatase 2A docking motifs in burst-attenuation of the cyclic AMP response element binding protein. The Journal of Biological Chemistry. 100908. PMID 34171357 DOI: 10.1016/j.jbc.2021.100908  0.32
2021 Polubothu S, Zecchin D, Al-Olabi L, Lionarons DA, Harland M, Horswell S, Thomas AC, Hunt L, Wlodarchak N, Aguilera P, Brand S, Bryant D, Carrera C, Chen H, Elgar G, ... ... Xing Y, et al. Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 34145395 DOI: 10.1038/s41436-021-01204-y  0.73
2021 Polubothu S, Zecchin D, Al-Olabi L, Lionarons DA, Harland M, Horswell S, Thomas AC, Hunt L, Wlodarchak N, Aguilera P, Brand S, Bryant D, Carrera C, Chen H, Elgar G, ... ... Xing Y, et al. Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 34145395 DOI: 10.1038/s41436-021-01204-y  0.73
2019 De Palma RM, Parnham SR, Li Y, Oaks JJ, Peterson YK, Szulc ZM, Roth BM, Xing Y, Ogretmen B. The NMR-based characterization of the FTY720-SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET-PP2A interaction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802264R. PMID 30917007 DOI: 10.1096/Fj.201802264R  0.369
2018 Zhang L, Zhou H, Li X, Vartuli RL, Rowse M, Xing Y, Rudra P, Ghosh D, Zhao R, Ford HL. Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression. Nature Communications. 9: 1047. PMID 29535359 DOI: 10.1038/S41467-018-03327-4  0.397
2017 Seok SH, Ma ZX, Feltenberger JB, Chen H, Chen H, Scarlett C, Lin Z, Satyshur KA, Cortopassi M, Jefcoate CR, Ge Y, Tang W, Bradfield CA, Xing Y. Trace Derivatives of Kynurenine Potently Activate the Aryl Hydrocarbon Receptor (AHR). The Journal of Biological Chemistry. PMID 29279331 DOI: 10.1074/Jbc.Ra117.000631  0.369
2017 Wu CG, Zheng A, Jiang L, Rowse M, Stanevich V, Chen H, Li Y, Satyshur KA, Johnson B, Gu TJ, Liu Z, Xing Y. Methylation-regulated decommissioning of multimeric PP2A complexes. Nature Communications. 8: 2272. PMID 29273778 DOI: 10.1038/S41467-017-02405-3  0.803
2017 Wu CG, Zheng A, Jiang L, Rowse M, Stanevich V, Chen H, Li Y, Satyshur KA, Johnson B, Gu TJ, Liu Z, Xing Y. Methylation-regulated decommissioning of multimeric PP2A complexes. Nature Communications. 8: 2272. PMID 29273778 DOI: 10.1038/S41467-017-02405-3  0.803
2017 Guo F, Wlodarchak N, Menden P, Xing Y. Purification of Target Proteins from Native Tissues: CCT Complex from Bovine Testes and PP2Ac from Porcine Brains. Methods in Molecular Biology (Clifton, N.J.). PMID 29247302 DOI: 10.1007/7651_2017_89  0.762
2017 Guo F, Wlodarchak N, Menden P, Xing Y. Purification of Target Proteins from Native Tissues: CCT Complex from Bovine Testes and PP2Ac from Porcine Brains. Methods in Molecular Biology (Clifton, N.J.). PMID 29247302 DOI: 10.1007/7651_2017_89  0.762
2017 Wu CG, Chen H, Guo F, Yadav VK, Mcilwain SJ, Rowse M, Choudhary A, Lin Z, Li Y, Gu T, Zheng A, Xu Q, Lee W, Resch E, Johnson B, ... ... Xing Y, et al. PP2A-B' holoenzyme substrate recognition, regulation and role in cytokinesis. Cell Discovery. 3: 17027. PMID 28884018 DOI: 10.1038/Celldisc.2017.27  0.425
2017 Seok SH, Lee W, Jiang L, Molugu K, Zheng A, Li Y, Park S, Bradfield CA, Xing Y. Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396409 DOI: 10.1073/Pnas.1617035114  0.384
2016 Wlodarchak N, Xing Y. PP2A as a master regulator of the cell cycle. Critical Reviews in Biochemistry and Molecular Biology. 1-23. PMID 26906453 DOI: 10.3109/10409238.2016.1143913  0.773
2016 Zhang Z, Hu F, Liu Y, Ma B, Chen X, Zhu K, Shi Y, Wei T, Xing Y, Gao Y, Lu H, Liu Y, Kang Q. Activation of type 5 metabotropic glutamate receptor promotes the proliferation of rat retinal progenitor cell via activation of the PI-3-K and MAPK signaling pathways. Neuroscience. PMID 26902516 DOI: 10.1016/J.Neuroscience.2016.02.030  0.381
2014 Kim H, Guo F, Brahma S, Xing Y, Burkard ME. Centralspindlin assembly and 2 phosphorylations on MgcRacGAP by Polo-like kinase 1 initiate Ect2 binding in early cytokinesis. Cell Cycle (Georgetown, Tex.). 13: 2952-61. PMID 25486482 DOI: 10.4161/15384101.2014.947201  0.37
2014 Guo R, Zheng L, Park JW, Lv R, Chen H, Jiao F, Xu W, Mu S, Wen H, Qiu J, Wang Z, Yang P, Wu F, Hui J, Fu X, ... Xing Y, et al. BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing. Molecular Cell. 56: 298-310. PMID 25263594 DOI: 10.1016/J.Molcel.2014.08.022  0.368
2014 Wang K, Shi Y, Zhang H, Xing Y, Dong Q, Ma T. Selenium as a photoabsorber for inorganic-organic hybrid solar cells. Physical Chemistry Chemical Physics : Pccp. 16: 23316-9. PMID 25259378 DOI: 10.1039/c4cp02821j  0.305
2014 Guo F, Wan L, Zheng A, Stanevich V, Wei Y, Satyshur KA, Shen M, Lee W, Kang Y, Xing Y. Structural insights into the tumor-promoting function of the MTDH-SND1 complex. Cell Reports. 8: 1704-13. PMID 25242325 DOI: 10.1016/J.Celrep.2014.08.033  0.784
2014 Wan L, Lu X, Yuan S, Wei Y, Guo F, Shen M, Yuan M, Chakrabarti R, Hua Y, Smith HA, Blanco MA, Chekmareva M, Wu H, Bronson RT, Haffty BG, ... Xing Y, et al. MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors. Cancer Cell. 26: 92-105. PMID 24981741 DOI: 10.1016/J.Ccr.2014.04.027  0.309
2014 Lackford B, Yao C, Charles GM, Weng L, Zheng X, Choi EA, Xie X, Wan J, Xing Y, Freudenberg JM, Yang P, Jothi R, Hu G, Shi Y. Fip1 regulates mRNA alternative polyadenylation to promote stem cell self-renewal. The Embo Journal. 33: 878-89. PMID 24596251 DOI: 10.1002/Embj.201386537  0.366
2014 Stanevich V, Zheng A, Guo F, Jiang L, Wlodarchak N, Xing Y. Mechanisms of the scaffold subunit in facilitating protein phosphatase 2A methylation Plos One. 9. PMID 24466300 DOI: 10.1371/Journal.Pone.0086955  0.769
2014 Kotlo K, Xing Y, Lather S, Grillon JM, Johnson K, Skidgel RA, Solaro RJ, Danziger RS. PR65A phosphorylation regulates PP2A complex signaling. Plos One. 9: e85000. PMID 24465463 DOI: 10.1371/Journal.Pone.0085000  0.428
2014 Guo F, Stanevich V, Wlodarchak N, Sengupta R, Jiang L, Satyshur KA, Xing Y. Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone. Cell Research. 24: 190-203. PMID 24100351 DOI: 10.1038/Cr.2013.138  0.766
2014 Xing Y, Kotlo K, Solaro R, Danziger R. Pr65A Phosphorylaion Regulates PP2A Complexation and Signaling Biophysical Journal. 106: 54a. DOI: 10.1016/J.Bpj.2013.11.379  0.448
2013 Yao C, Choi EA, Weng L, Xie X, Wan J, Xing Y, Moresco JJ, Tu PG, Yates JR, Shi Y. Overlapping and distinct functions of CstF64 and CstF64Ï„ in mammalian mRNA 3' processing. Rna (New York, N.Y.). 19: 1781-90. PMID 24149845 DOI: 10.1261/Rna.042317.113  0.354
2013 Wlodarchak N, Guo F, Satyshur KA, Jiang L, Jeffrey PD, Sun T, Stanevich V, Mumby MC, Xing Y. Structure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation. Cell Research. 23: 931-46. PMID 23752926 DOI: 10.1038/Cr.2013.77  0.769
2013 Jiang L, Stanevich V, Satyshur KA, Kong M, Watkins GR, Wadzinski BE, Sengupta R, Xing Y. Structural basis of protein phosphatase 2A stable latency. Nature Communications. 4: 1699. PMID 23591866 DOI: 10.1038/Ncomms2663  0.807
2012 Yao C, Biesinger J, Wan J, Weng L, Xing Y, Xie X, Shi Y. Transcriptome-wide analyses of CstF64-RNA interactions in global regulation of mRNA alternative polyadenylation. Proceedings of the National Academy of Sciences of the United States of America. 109: 18773-8. PMID 23112178 DOI: 10.1073/Pnas.1211101109  0.355
2012 Mezrich JD, Nguyen LP, Kennedy G, Nukaya M, Fechner JH, Zhang X, Xing Y, Bradfield CA. SU5416, a VEGF receptor inhibitor and ligand of the AHR, represents a new alternative for immunomodulation. Plos One. 7: e44547. PMID 22970246 DOI: 10.1371/Journal.Pone.0044547  0.32
2012 Xing Y, Nukaya M, Satyshur KA, Jiang L, Stanevich V, Korkmaz EN, Burdette L, Kennedy GD, Cui Q, Bradfield CA. Identification of the Ah-receptor structural determinants for ligand preferences. Toxicological Sciences : An Official Journal of the Society of Toxicology. 129: 86-97. PMID 22659362 DOI: 10.1093/Toxsci/Kfs194  0.768
2011 Shi Y, Yang S, Troup S, Lu X, Callaghan S, Park DS, Xing Y, Yang X. Resveratrol induces apoptosis in breast cancer cells by E2F1-mediated up-regulation of ASPP1. Oncology Reports. 25: 1713-9. PMID 21479363 DOI: 10.3892/or.2011.1248  0.325
2011 Stanevich V, Jiang L, Satyshur KA, Li Y, Jeffrey PD, Li Z, Menden P, Semmelhack MF, Xing Y. The Structural Basis for Tight Control of PP2A Methylation and Function by LCMT-1 Molecular Cell. 41: 331-342. PMID 21292165 DOI: 10.1016/J.Molcel.2010.12.030  0.806
2009 Dickerson SJ, Xing Y, Robinson AR, Seaman WT, Gruffat H, Kenney SC. Methylation-dependent binding of the epstein-barr virus BZLF1 protein to viral promoters. Plos Pathogens. 5: e1000356. PMID 19325883 DOI: 10.1371/Journal.Ppat.1000356  0.351
2008 Du YF, Shi Y, Xing YF, Xing YF, Zeng FQ, Zeng FQ. Establishment of CXCR4-small interfering RNA retrovirus vector driven by human prostate-specific antigen promoter and its biological effects on prostate cancer in vitro and in vivo. Journal of Cancer Research and Clinical Oncology. 134: 1255-64. PMID 18431597 DOI: 10.1007/s00432-008-0394-2  0.304
2008 Xing Y, Li Z, Chen Y, Stock JB, Jeffrey PD, Shi Y. Structural mechanism of demethylation and inactivation of protein phosphatase 2A. Cell. 133: 154-63. PMID 18394995 DOI: 10.1016/J.Cell.2008.02.041  0.64
2007 Chen Y, Xu Y, Bao Q, Xing Y, Li Z, Lin Z, Stock JB, Jeffrey PD, Shi Y. Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Nature Structural & Molecular Biology. 14: 527-34. PMID 17529992 DOI: 10.1038/Nsmb1254  0.781
2007 Zhao X, Tang R, Gao B, Shi Y, Zhou J, Guo S, Zhang J, Wang Y, Tang W, Meng J, Li S, Wang H, Ma G, Lin C, Xiao Y, ... ... Xing Y, et al. Functional variants in the promoter region of Chitinase 3-like 1 (CHI3L1) and susceptibility to schizophrenia. American Journal of Human Genetics. 80: 12-8. PMID 17160890 DOI: 10.1086/510438  0.319
2006 Xu Y, Xing Y, Chen Y, Chao Y, Lin Z, Fan E, Yu JW, Strack S, Jeffrey PD, Shi Y. Structure of the protein phosphatase 2A holoenzyme. Cell. 127: 1239-51. PMID 17174897 DOI: 10.1016/J.Cell.2006.11.033  0.739
2006 Xing Y, Xu Y, Chen Y, Jeffrey PD, Chao Y, Lin Z, Li Z, Strack S, Stock JB, Shi Y. Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins. Cell. 127: 341-53. PMID 17055435 DOI: 10.1016/J.Cell.2006.09.025  0.744
2006 Chao Y, Xing Y, Chen Y, Xu Y, Lin Z, Li Z, Jeffrey PD, Stock JB, Shi Y. Structure and mechanism of the phosphotyrosyl phosphatase activator. Molecular Cell. 23: 535-46. PMID 16916641 DOI: 10.1016/J.Molcel.2006.07.027  0.752
2005 Bernard MP, Lin W, Myers R, Cao D, Xing Y, Moyle WR. Crosslinked bifunctional gonadotropin analogs with reduced efficacy. Molecular and Cellular Endocrinology. 233: 25-31. PMID 15767043 DOI: 10.1016/J.Mce.2005.01.008  0.302
2004 Bernard MP, Lin W, Cao D, Myers RV, Xing Y, Moyle WR. Only a portion of the small seatbelt loop in human choriogonadotropin appears capable of contacting the lutropin receptor. The Journal of Biological Chemistry. 279: 44438-41. PMID 15304512 DOI: 10.1074/Jbc.M406932200  0.373
2004 Moyle WR, Xing Y, Lin W, Cao D, Myers RV, Kerrigan JE, Bernard MP. Model of glycoprotein hormone receptor ligand binding and signaling. The Journal of Biological Chemistry. 279: 44442-59. PMID 15304493 DOI: 10.1074/Jbc.M406948200  0.315
2004 Xing Y, Lin W, Jiang M, Cao D, Myers RV, Bernard MP, Moyle WR. Use of protein knobs to characterize the position of conserved alpha-subunit regions in lutropin receptor complexes. The Journal of Biological Chemistry. 279: 44427-37. PMID 15304492 DOI: 10.1074/Jbc.M406931200  0.371
2004 Xing Y, Myers RV, Cao D, Lin W, Jiang M, Bernard MP, Moyle WR. Glycoprotein hormone assembly in the endoplasmic reticulum: IV. Probable mechanism of subunit docking and completion of assembly. The Journal of Biological Chemistry. 279: 35458-68. PMID 15166248 DOI: 10.1074/Jbc.M403055200  0.348
2004 Xing Y, Myers RV, Cao D, Lin W, Jiang M, Bernard MP, Moyle WR. Glycoprotein hormone assembly in the endoplasmic reticulum: I. The glycosylated end of human alpha-subunit loop 2 is threaded through a beta-subunit hole. The Journal of Biological Chemistry. 279: 35426-36. PMID 15161918 DOI: 10.1074/Jbc.M403052200  0.358
2004 Xing Y, Myers RV, Cao D, Lin W, Jiang M, Bernard MP, Moyle WR. Glycoprotein hormone assembly in the endoplasmic reticulum: III. The seatbelt and its latch site determine the assembly pathway. The Journal of Biological Chemistry. 279: 35449-57. PMID 15161904 DOI: 10.1074/Jbc.M403054200  0.319
2004 Xing Y, Myers RV, Cao D, Lin W, Jiang M, Bernard MP, Moyle WR. Glycoprotein hormone assembly in the endoplasmic reticulum: II. Multiple roles of a redox sensitive beta-subunit disulfide switch. The Journal of Biological Chemistry. 279: 35437-48. PMID 15161903 DOI: 10.1074/Jbc.M403053200  0.315
2003 Xing Y, Moyle WR. Efficient preparation of glycoprotein hormones lacking an alpha-subunit oligosaccharide. Biochemical and Biophysical Research Communications. 303: 201-5. PMID 12646187 DOI: 10.1016/S0006-291X(03)00322-X  0.303
2001 Xing Y, Lin W, Jiang M, Myers RV, Cao D, Bernard MP, Moyle WR. Alternatively folded choriogonadotropin analogs. Implications for hormone folding and biological activity. The Journal of Biological Chemistry. 276: 46953-60. PMID 11591722 DOI: 10.1074/Jbc.M108374200  0.36
2001 Xing Y, Williams C, Campbell RK, Cook S, Knoppers M, Addona T, Altarocca V, Moyle WR. Threading of a glycosylated protein loop through a protein hole: Implications for combination of human chorionic gonadotropin subunits Protein Science. 10: 226-235. PMID 11266609 DOI: 10.1110/Ps.25901  0.347
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