| Year |
Citation |
Score |
| 2024 |
Gern BH, Klas JM, Foster KA, Cohen SB, Plumlee CR, Duffy FJ, Neal ML, Halima M, Gustin AT, Diercks AH, Aderem A, Gale M, Aitchison JD, Gerner MY, Urdahl KB. CD4-mediated immunity shapes neutrophil-driven tuberculous pathology. Biorxiv : the Preprint Server For Biology. PMID 38659794 DOI: 10.1101/2024.04.12.589315 |
0.503 |
|
| 2024 |
Mai D, Jahn A, Murray T, Morikubo M, Lim PN, Cervantes MM, Pham LK, Nemeth J, Urdahl K, Diercks AH, Aderem A, Rothchild AC. Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection. Plos Pathogens. 20: e1011871. PMID 38236787 DOI: 10.1371/journal.ppat.1011871 |
0.517 |
|
| 2021 |
Olson GS, Murray TA, Jahn AN, Mai D, Diercks AH, Gold ES, Aderem A. Type I interferon decreases macrophage energy metabolism during mycobacterial infection. Cell Reports. 35: 109195. PMID 34077724 DOI: 10.1016/j.celrep.2021.109195 |
0.385 |
|
| 2021 |
Nazitto R, Amon LM, Mast FD, Aitchison JD, Aderem A, Johnson JS, Diercks AH. ILF3 Is a Negative Transcriptional Regulator of Innate Immune Responses and Myeloid Dendritic Cell Maturation. Journal of Immunology (Baltimore, Md. : 1950). PMID 34031149 DOI: 10.4049/jimmunol.2001235 |
0.381 |
|
| 2021 |
Duffy FJ, Olson GS, Gold ES, Jahn A, Aderem A, Aitchison J, Rothchild AC, Diercks AH, Nemeth J. A contained Mycobacterium tuberculosis mouse infection model predicts active disease and containment in humans. The Journal of Infectious Diseases. PMID 33693706 DOI: 10.1093/infdis/jiab130 |
0.689 |
|
| 2020 |
Su Y, Chen D, Yuan D, Lausted C, Choi J, Dai CL, Voillet V, Duvvuri VR, Scherler K, Troisch P, Baloni P, Qin G, Smith B, Kornilov SA, Rostomily C, ... ... Aderem A, et al. Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19. Cell. PMID 33171100 DOI: 10.1016/j.cell.2020.10.037 |
0.682 |
|
| 2020 |
Rothchild AC, Mai D, Aderem A, Diercks AH. Flow Cytometry Analysis and Fluorescence-activated Cell Sorting of Myeloid Cells from Lung and Bronchoalveolar Lavage Samples from -infected Mice. Bio-Protocol. 10. PMID 32995363 DOI: 10.21769/bioprotoc.3630 |
0.75 |
|
| 2020 |
Su Y, Chen D, Lausted C, Yuan D, Choi J, Dai C, Voillet V, Scherler K, Troisch P, Duvvuri VR, Baloni P, Qin G, Smith B, Kornilov S, Rostomily C, ... ... Aderem A, et al. Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories. Biorxiv : the Preprint Server For Biology. PMID 32766585 DOI: 10.1101/2020.07.27.224063 |
0.71 |
|
| 2020 |
Nemeth J, Olson GS, Rothchild AC, Jahn AN, Mai D, Duffy FJ, Delahaye JL, Srivatsan S, Plumlee CR, Urdahl KB, Gold ES, Aderem A, Diercks AH. Contained Mycobacterium tuberculosis infection induces concomitant and heterologous protection. Plos Pathogens. 16: e1008655. PMID 32673357 DOI: 10.1371/Journal.Ppat.1008655 |
0.779 |
|
| 2020 |
Tam VC, Suen R, Treuting PM, Armando A, Lucarelli R, Gorrochotegui-Escalante N, Diercks AH, Quehenberger O, Dennis EA, Aderem A, Gold ES. PPARα exacerbates necroptosis, leading to increased mortality in postinfluenza bacterial superinfection. Proceedings of the National Academy of Sciences of the United States of America. PMID 32581129 DOI: 10.1073/Pnas.2006343117 |
0.377 |
|
| 2020 |
Du Y, Thompson EG, Muller J, Valvo J, Braun J, Shankar S, van den Berg RA, Jongert E, Dover D, Sadoff J, Hendriks J, Gardner MJ, Ballou WR, Regules JA, van der Most R, ... Aderem A, et al. The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection. Frontiers in Immunology. 11: 669. PMID 32411130 DOI: 10.3389/Fimmu.2020.00669 |
0.349 |
|
| 2020 |
Johnson JS, De Veaux N, Rives AW, Lahaye X, Lucas SY, Perot BP, Luka M, Garcia-Paredes V, Amon LM, Watters A, Abdessalem G, Aderem A, Manel N, Littman DR, Bonneau R, et al. A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV. Cell Reports. 30: 914-931.e9. PMID 31968263 DOI: 10.1016/J.Celrep.2019.12.054 |
0.367 |
|
| 2019 |
Rothchild AC, Olson GS, Nemeth J, Amon LM, Mai D, Gold ES, Diercks AH, Aderem A. Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response in vivo. Science Immunology. 4. PMID 31350281 DOI: 10.1126/Sciimmunol.Aaw6693 |
0.767 |
|
| 2019 |
Baazim H, Schweiger M, Moschinger M, Xu H, Scherer T, Popa A, Gallage S, Ali A, Khamina K, Kosack L, Vilagos B, Smyth M, Lercher A, Friske J, Merkler D, ... Aderem A, et al. CD8 T cells induce cachexia during chronic viral infection. Nature Immunology. PMID 31110314 DOI: 10.1038/S41590-019-0397-Y |
0.335 |
|
| 2019 |
Peterson EJ, Bailo R, Rothchild AC, Arrieta-Ortiz ML, Kaur A, Pan M, Mai D, Abidi AA, Cooper C, Aderem A, Bhatt A, Baliga NS. Path-seq identifies an essential mycolate remodeling program for mycobacterial host adaptation. Molecular Systems Biology. 15: e8584. PMID 30833303 DOI: 10.15252/Msb.20188584 |
0.717 |
|
| 2018 |
Suliman S, Thompson E, Sutherland J, Weiner Rd J, Ota MOC, Shankar S, Penn-Nicholson A, Thiel B, Erasmus M, Maertzdorf J, Duffy FJ, Hill PC, Hughes EJ, Stanley K, Downing K, ... ... Aderem A, et al. Four-gene Pan-African Blood Signature Predicts Progression to Tuberculosis. American Journal of Respiratory and Critical Care Medicine. PMID 29624071 DOI: 10.1164/Rccm.201711-2340Oc |
0.327 |
|
| 2018 |
Johnson JS, Lucas SY, Amon LM, Skelton S, Nazitto R, Carbonetti S, Sather DN, Littman DR, Aderem A. Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection. Cell Host & Microbe. 23: 366-381.e9. PMID 29544097 DOI: 10.1016/J.Chom.2018.01.012 |
0.313 |
|
| 2018 |
Hansen SG, Zak DE, Xu G, Ford JC, Marshall EE, Malouli D, Gilbride RM, Hughes CM, Ventura AB, Ainslie E, Randall KT, Selseth AN, Rundstrom P, Herlache L, Lewis MS, ... ... Aderem A, et al. Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine. Nature Medicine. PMID 29334373 DOI: 10.1038/Nm.4473 |
0.387 |
|
| 2018 |
Thompson EG, Shankar S, Gideon HP, Braun J, Valvo J, Skinner J, Aderem A, Flynn JL, Lin PL, Zak DE. Blood RNA signatures prospectively discriminate controllers from progressors early after low-dose M. tuberculosis infection of cynomolgus macaques. The Journal of Infectious Diseases. PMID 29325117 DOI: 10.1093/Infdis/Jiy006 |
0.371 |
|
| 2017 |
Scriba TJ, Penn-Nicholson A, Shankar S, Hraha T, Thompson EG, Sterling D, Nemes E, Darboe F, Suliman S, Amon LM, Mahomed H, Erasmus M, Whatney W, Johnson JL, Boom WH, ... ... Aderem A, et al. Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease. Plos Pathogens. 13: e1006687. PMID 29145483 DOI: 10.1371/Journal.Ppat.1006687 |
0.384 |
|
| 2017 |
Askovich PS, Ramsey SA, Diercks AH, Kennedy KA, Knijnenburg TA, Aderem A. Identifying novel transcription factors involved in the inflammatory response by using binding site motif scanning in genomic regions defined by histone acetylation. Plos One. 12: e0184850. PMID 28922390 DOI: 10.1371/journal.pone.0184850 |
0.383 |
|
| 2017 |
Kazmin D, Nakaya HI, Lee EK, Johnson MJ, van der Most R, van den Berg RA, Ballou WR, Jongert E, Wille-Reece U, Ockenhouse C, Aderem A, Zak DE, Sadoff J, Hendriks J, Wrammert J, et al. Systems analysis of protective immune responses to RTS,S malaria vaccination in humans. Proceedings of the National Academy of Sciences of the United States of America. PMID 28193898 DOI: 10.1073/Pnas.1621489114 |
0.384 |
|
| 2016 |
Rothchild AC, Sissons JR, Shafiani S, Plaisier C, Min D, Mai D, Gilchrist M, Peschon J, Larson RP, Bergthaler A, Baliga NS, Urdahl KB, Aderem A. MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 27681624 DOI: 10.1073/Pnas.1608255113 |
0.698 |
|
| 2015 |
Zak DE, Aderem A. Systems integration of innate and adaptive immunity. Vaccine. 33: 5241-8. PMID 26102534 DOI: 10.1016/J.Vaccine.2015.05.098 |
0.334 |
|
| 2015 |
Cronk JC, Derecki NC, Ji E, Xu Y, Lampano AE, Smirnov I, Baker W, Norris GT, Marin I, Coddington N, Wolf Y, Turner SD, Aderem A, Klibanov AL, Harris TH, et al. Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli. Immunity. 42: 679-91. PMID 25902482 DOI: 10.1016/J.Immuni.2015.03.013 |
0.307 |
|
| 2015 |
Quinn KM, Zak DE, Costa A, Yamamoto A, Kastenmuller K, Hill BJ, Lynn GM, Darrah PA, Lindsay RW, Wang L, Cheng C, Nicosia A, Folgori A, Colloca S, Cortese R, ... ... Aderem A, et al. Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling. The Journal of Clinical Investigation. 125: 1129-46. PMID 25642773 DOI: 10.1172/Jci78280 |
0.349 |
|
| 2015 |
Schliehe C, Flynn EK, Vilagos B, Richson U, Swaminathan S, Bosnjak B, Bauer L, Kandasamy RK, Griesshammer IM, Kosack L, Schmitz F, Litvak V, Sissons J, Lercher A, Bhattacharya A, ... ... Aderem A, et al. The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. Nature Immunology. 16: 67-74. PMID 25419628 DOI: 10.1038/Ni.3046 |
0.326 |
|
| 2014 |
Aevermann BD, Pickett BE, Kumar S, Klem EB, Agnihothram S, Askovich PS, Bankhead A, Bolles M, Carter V, Chang J, Clauss TR, Dash P, Diercks AH, Eisfeld AJ, Ellis A, ... ... Aderem A, et al. A comprehensive collection of systems biology data characterizing the host response to viral infection. Scientific Data. 1: 140033. PMID 25977790 DOI: 10.1038/Sdata.2014.33 |
0.368 |
|
| 2014 |
Tam VC, Aderem A. Macrophage activation as an effector mechanism for cell-mediated immunity. Journal of Immunology (Baltimore, Md. : 1950). 193: 3183-4. PMID 25240016 DOI: 10.4049/Jimmunol.1402046 |
0.381 |
|
| 2014 |
Rosenberger CM, Podyminogin RL, Askovich PS, Navarro G, Kaiser SM, Sanders CJ, McClaren JL, Tam VC, Dash P, Noonan JG, Jones BG, Surman SL, Peschon JJ, Diercks AH, Hurwitz JL, ... ... Aderem A, et al. Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model. The Journal of General Virology. 95: 350-62. PMID 24243730 DOI: 10.1099/Vir.0.058438-0 |
0.354 |
|
| 2013 |
Askovich PS, Sanders CJ, Rosenberger CM, Diercks AH, Dash P, Navarro G, Vogel P, Doherty PC, Thomas PG, Aderem A. Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses. Plos One. 8: e74863. PMID 24073225 DOI: 10.1371/Journal.Pone.0074863 |
0.318 |
|
| 2013 |
Tam VC, Quehenberger O, Oshansky CM, Suen R, Armando AM, Treuting PM, Thomas PG, Dennis EA, Aderem A. Lipidomic profiling of influenza infection identifies mediators that induce and resolve inflammation. Cell. 154: 213-27. PMID 23827684 DOI: 10.1016/J.Cell.2013.05.052 |
0.365 |
|
| 2013 |
Diercks A, Aderem A. Systems approaches to dissecting immunity. Current Topics in Microbiology and Immunology. 363: 1-19. PMID 22886541 DOI: 10.1007/82_2012_246 |
0.318 |
|
| 2012 |
Nakayama M, Kurokawa K, Nakamura K, Lee BL, Sekimizu K, Kubagawa H, Hiramatsu K, Yagita H, Okumura K, Takai T, Underhill DM, Aderem A, Ogasawara K. Inhibitory receptor paired Ig-like receptor B is exploited by Staphylococcus aureus for virulence. Journal of Immunology (Baltimore, Md. : 1950). 189: 5903-11. PMID 23152562 DOI: 10.4049/Jimmunol.1201940 |
0.366 |
|
| 2012 |
Zak DE, Andersen-Nissen E, Peterson ER, Sato A, Hamilton MK, Borgerding J, Krishnamurty AT, Chang JT, Adams DJ, Hensley TR, Salter AI, Morgan CA, Duerr AC, De Rosa SC, Aderem A, et al. Merck Ad5/HIV induces broad innate immune activation that predicts CD8⁺ T-cell responses but is attenuated by preexisting Ad5 immunity. Proceedings of the National Academy of Sciences of the United States of America. 109: E3503-12. PMID 23151505 DOI: 10.1073/Pnas.1208972109 |
0.349 |
|
| 2012 |
Negishi H, Yanai H, Nakajima A, Koshiba R, Atarashi K, Matsuda A, Matsuki K, Miki S, Doi T, Aderem A, Nishio J, Smale ST, Honda K, Taniguchi T. Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses. Nature Immunology. 13: 659-66. PMID 22610141 DOI: 10.1038/Ni.2307 |
0.396 |
|
| 2011 |
Zak DE, Schmitz F, Gold ES, Diercks AH, Peschon JJ, Valvo JS, Niemistö A, Podolsky I, Fallen SG, Suen R, Stolyar T, Johnson CD, Kennedy KA, Hamilton MK, Siggs OM, ... ... Aderem A, et al. Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses. Proceedings of the National Academy of Sciences of the United States of America. 108: 11536-41. PMID 21709223 DOI: 10.1073/Pnas.1107577108 |
0.305 |
|
| 2009 |
Hertz AL, Bender AT, Smith KC, Gilchrist M, Amieux PS, Aderem A, Beavo JA. Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophages. Proceedings of the National Academy of Sciences of the United States of America. 106: 21978-83. PMID 19959669 DOI: 10.1073/Pnas.0911684106 |
0.317 |
|
| 2009 |
Zak DE, Aderem A. A systems view of host defense. Nature Biotechnology. 27: 999-1001. PMID 19898453 DOI: 10.1038/Nbt1109-999 |
0.333 |
|
| 2009 |
Litvak V, Ramsey SA, Rust AG, Zak DE, Kennedy KA, Lampano AE, Nykter M, Shmulevich I, Aderem A. Function of C/EBPdelta in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals. Nature Immunology. 10: 437-43. PMID 19270711 DOI: 10.1038/Ni.1721 |
0.349 |
|
| 2008 |
Thuong NT, Dunstan SJ, Chau TT, Thorsson V, Simmons CP, Quyen NT, Thwaites GE, Thi Ngoc Lan N, Hibberd M, Teo YY, Seielstad M, Aderem A, Farrar JJ, Hawn TR. Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles. Plos Pathogens. 4: e1000229. PMID 19057661 DOI: 10.1371/Journal.Ppat.1000229 |
0.309 |
|
| 2008 |
Gilchrist M, Henderson WR, Clark AE, Simmons RM, Ye X, Smith KD, Aderem A. Activating transcription factor 3 is a negative regulator of allergic pulmonary inflammation. The Journal of Experimental Medicine. 205: 2349-57. PMID 18794337 DOI: 10.1084/jem.20072254 |
0.346 |
|
| 2008 |
Charles JF, Humphrey MB, Zhao X, Quarles E, Nakamura MC, Aderem A, Seaman WE, Smith KD. The innate immune response to Salmonella enterica serovar Typhimurium by macrophages is dependent on TREM2-DAP12. Infection and Immunity. 76: 2439-47. PMID 18391000 DOI: 10.1128/Iai.00115-08 |
0.387 |
|
| 2008 |
Rosenberger CM, Clark AE, Treuting PM, Johnson CD, Aderem A. ATF3 regulates MCMV infection in mice by modulating IFN-gamma expression in natural killer cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 2544-9. PMID 18268321 DOI: 10.1073/Pnas.0712182105 |
0.361 |
|
| 2007 |
Hawn TR, Berrington WR, Smith IA, Uematsu S, Akira S, Aderem A, Smith KD, Skerrett SJ. Altered inflammatory responses in TLR5-deficient mice infected with Legionella pneumophila. Journal of Immunology (Baltimore, Md. : 1950). 179: 6981-7. PMID 17982089 |
0.415 |
|
| 2007 |
Miao EA, Andersen-Nissen E, Warren SE, Aderem A. TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system. Seminars in Immunopathology. 29: 275-88. PMID 17690885 DOI: 10.1007/s00281-007-0078-z |
0.418 |
|
| 2007 |
Hawn TR, Misch EA, Dunstan SJ, Thwaites GE, Lan NT, Quy HT, Chau TT, Rodrigues S, Nachman A, Janer M, Hien TT, Farrar JJ, Aderem A. A common human TLR1 polymorphism regulates the innate immune response to lipopeptides. European Journal of Immunology. 37: 2280-9. PMID 17595679 DOI: 10.1002/eji.200737034 |
0.377 |
|
| 2007 |
Andersen-Nissen E, Hawn TR, Smith KD, Nachman A, Lampano AE, Uematsu S, Akira S, Aderem A. Cutting edge: Tlr5-/- mice are more susceptible to Escherichia coli urinary tract infection. Journal of Immunology (Baltimore, Md. : 1950). 178: 4717-20. PMID 17404249 |
0.375 |
|
| 2006 |
Hawn TR, Smith KD, Aderem A, Skerrett SJ. Myeloid differentiation primary response gene (88)- and toll-like receptor 2-deficient mice are susceptible to infection with aerosolized Legionella pneumophila. The Journal of Infectious Diseases. 193: 1693-702. PMID 16703513 DOI: 10.1086/504525 |
0.413 |
|
| 2005 |
Bergman MA, Cummings LA, Barrett SL, Smith KD, Lara JC, Aderem A, Cookson BT. CD4+ T cells and toll-like receptors recognize Salmonella antigens expressed in bacterial surface organelles. Infection and Immunity. 73: 1350-6. PMID 15731032 DOI: 10.1128/Iai.73.3.1350-1356.2005 |
0.348 |
|
| 2004 |
Flo TH, Smith KD, Sato S, Rodriguez DJ, Holmes MA, Strong RK, Akira S, Aderem A. Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature. 432: 917-21. PMID 15531878 DOI: 10.1038/Nature03104 |
0.34 |
|
| 2004 |
Gold ES, Simmons RM, Petersen TW, Campbell LA, Kuo CC, Aderem A. Amphiphysin IIm is required for survival of Chlamydia pneumoniae in macrophages. The Journal of Experimental Medicine. 200: 581-6. PMID 15337791 DOI: 10.1084/Jem.20040546 |
0.317 |
|
| 2003 |
Hawn TR, Verbon A, Lettinga KD, Zhao LP, Li SS, Laws RJ, Skerrett SJ, Beutler B, Schroeder L, Nachman A, Ozinsky A, Smith KD, Aderem A. A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. The Journal of Experimental Medicine. 198: 1563-72. PMID 14623910 DOI: 10.1084/Jem.20031220 |
0.426 |
|
| 2003 |
Marr KA, Balajee SA, Hawn TR, Ozinsky A, Pham U, Akira S, Aderem A, Liles WC. Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens. Infection and Immunity. 71: 5280-6. PMID 12933875 DOI: 10.1128/IAI.71.9.5280-5286.2003 |
0.388 |
|
| 2003 |
Aderem A. Phagocytosis and the inflammatory response. The Journal of Infectious Diseases. S340-5. PMID 12792849 DOI: 10.1086/374747 |
0.338 |
|
| 2003 |
Means TK, Hayashi F, Smith KD, Aderem A, Luster AD. The Toll-like receptor 5 stimulus bacterial flagellin induces maturation and chemokine production in human dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 170: 5165-75. PMID 12734364 |
0.336 |
|
| 2003 |
Bochud PY, Hawn TR, Aderem A. Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling. Journal of Immunology (Baltimore, Md. : 1950). 170: 3451-4. PMID 12646604 DOI: 10.4049/jimmunol.170.7.3451 |
0.386 |
|
| 2002 |
Hamerman JA, Hayashi F, Schroeder LA, Gygi SP, Haas AL, Hampson L, Coughlin P, Aebersold R, Aderem A. Serpin 2a is induced in activated macrophages and conjugates to a ubiquitin homolog. Journal of Immunology (Baltimore, Md. : 1950). 168: 2415-23. PMID 11859133 DOI: 10.4049/Jimmunol.168.5.2415 |
0.376 |
|
| 2002 |
Ravasi T, Wells C, Forrest A, Underhill DM, Wainwright BJ, Aderem A, Grimmond S, Hume DA. Generation of diversity in the innate immune system: Macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes Journal of Immunology. 168: 44-50. PMID 11751944 DOI: 10.4049/jimmunol.168.1.44 |
0.3 |
|
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