1990 — 2000 |
Haley, William E |
P01Activity Code Description: For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal. |
Caregiver Coping--Racial and Longitudinal Effects @ University of Alabama At Birmingham
Many patients with AD are cared for in the community by their family members, and these family caregivers are at risk for negative psychosocial and health consequences due to the chronic stress experienced. The long- term effects of caregiving stress after patients death, nursing home placement, or continual caregiving, are poorly understood, particularly among African-American caregivers. The present project will utilize a stress and coping model to study the psychosocial and health consequences of caregiving, with special emphasis on racial differences and the longitudinal course of caregiver adjustment. Specifically,a the project will conduct longitudinal follow-ups of samples of White caregivers (demographically matched with White noncaregiving controls) African=American caregivers (demographically matched with White noncaregiving controls) and African-American caregivers (demographically matched with African-American noncaregiving controls). Most of these subjects have already been recruited, but 80 additional subjects will be added to the sample during the first two years of the proposed project. Data from these individuals will be collected on an annual basis over athe course of the project with a battery of measures assessing caregiver psychological, social, and health adjustment, stressful life events, patient objective impairment and caregiver appraisal.,, and caregiver coping responses. Additional specialized assessments will be done in the event of patients death or institutionalization. Longitudinal follow-up procedures have already been successfully established and pilot data is available from the ongoing caregiver research study. This data will provide information relevant to: 1) the longitudinal effects of the stress of continued caregiving on caregiver psychosocial and health outcomes among African-American and White families, beyond those experienced by 2) ascertaining prospectively the long-term effects of nursing home placement and patient death on caregiver adjustment, and 3) exploring variables which predict individual differences in caregiver adjustment, and 3) exploring variables which predict individual differences in caregiver adjustment over time, including severity of patient impairment and stressful life events, appraisal, social support, and coping. The emphasis on assessing the special strengths and problems experienced by African-American families, and the long-term course of caregiving stress among African-American and White families, will be of particular importance.
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0.948 |
2002 |
Haley, William E |
R03Activity Code Description: To provide research support specifically limited in time and amount for studies in categorical program areas. Small grants provide flexibility for initiating studies which are generally for preliminary short-term projects and are non-renewable. |
Quality of Life in Older Breast Cancer Survivors @ University of South Florida
Increasing numbers of older women are surviving cancer after successful medical treatment, with the potential for both positive and negative long- term outcomes. Women surviving breast cancer face unique problems and concerns, including the physical and psychological sequelae of cancer treatments and fears concerning cancer recurrence. Psychosocial cancer research has primarily focused on younger women, despite the fact that older women are at the highest risk for cancer and often have multiple chronic illnesses and other factors putting them at risk for complications. The proposed project will be among the first studies to examine the long-term impact of surviving cancer among older adults, and will provide valuable information that can be used to design cancer intervention programs for older adults that target their special needs and concerns. It will be a collaborative effort between the Department of Gerontology at the University of South Florida and the Senior Adult Oncology Program (SAOP) at the Moffitt Cancer Center and Research Institute, one of the few programs nationally specializing in cancer care for older persons. The proposed project will study the impact of breast cancer on disability and quality of life in older women, with the overall goal of providing information of value to older women, their families, and health care professionals. Participants will be drawn from a database of 298 women with breast cancer seen by the SAOP from 1994-2001. Cancer survivors will be administered a battery of tests to assess disability, quality of life, and psychological growth, and will be compared to a non-cancer control group taken from over 250 older women in the Charlotte County Healthy Aging Study. Specific aims are to (1) develop a description of outcomes among older adult breast cancer survivors, including quality of life, functional impairment, and independence and how these vary over length of survival; (2) identify predictors of change in depression, functional impairment and independent living status from initial patient information; and (3) examine survivor perceptions of cancer-related services and their suitability for older adults.
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1 |