We are testing a new system for linking grants to scientists.
The funding information displayed below comes from the
NIH Research Portfolio Online Reporting Tools and the
NSF Award Database.
The grant data on this page is limited to grants awarded in the United States and is thus partial. It can nonetheless be used to understand how funding patterns influence mentorship networks and vice-versa, which has deep implications on how research is done.
You can help! If you notice any innacuracies, please
sign in and mark grants as correct or incorrect matches.
Sign in to see low-probability grants and correct any errors in linkage between grants and researchers.
High-probability grants
According to our matching algorithm, Eleanore B. Edson is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
2002 — 2004 |
Edson, Eleanore B |
F31Activity Code Description: To provide predoctoral individuals with supervised research training in specified health and health-related areas leading toward the research degree (e.g., Ph.D.). |
Role of Class I Mhc in Synaptic Refinement &Plasticity @ Harvard University (Medical School)
DESCRIPTION (provided by applicant): These experiments are intended to gain insight into the synaptic mechanisms by which class I MHC affects the refinement and plasticity of hippocampal synapses. Because members of the class I MHC gene family are expressed by neurons in many brain regions, the findings may help determine general principles governing activity-dependent events in other brain regions. The specific aims of the proposal seek to: first, determine the subcellular localization of class I MHC in hippocampal pyramidal cell synapses; second, to determine if class I MHC is necessary for development of hippocampal fine structure; third, determine if class I MHC is necessary for basal synaptic transmission in hippocampal pyramidal cells. Thus, the results from these experiments will directly address the hypothesis that short-term changes in synaptic strength lead to long-term changes in synaptic structure. Further, deducing MHC l's role in synaptic refinement and plasticity could provide crucial insight into a number of debilitating diseases for two reasons: first, neurodevelopmental and neurodegenerative diseases may wreck havoc on the brain via selective targeting of neurons with specific expression patterns of MHC I. Second, a genetic linkage exists between MHC I and a number of diseases with a neurological component, including: multiple sclerosis, ALS, epilepsy, spinocerrebellar ataxia, Huntington's disease, Parkinson's disease, and dyslexia.
|
1 |