2004 — 2007 |
Hays, Ronald Dale |
P01Activity Code Description: For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal. |
Mode and Language Evaluation of Generic Measures @ University of Wisconsin Madison
We propose to assess the impact of mode of administration (self-administered versus interviewer administered) and language of administration (English versus Spanish) on response to four leading generic health-related quality of life (HRQOL) measures (SF-36, EQ-5D, Quality of Well-Being scale, Health Utilities Index). The specific aims of this project are to: 1) evaluate the psychometric equivalence by mode and language of administration for the 4 generic HRQOL measures in terms of missing data, central tendency, variance, reliability, item difficulty, and item discrimination (slopes); 2) examine correlations between self and interviewer-administered responses to the same HRQOL measure, and between the same constructs measured by different measures; 3) predict self-administered HRQOL responses from interviewer-administered responses (and vice versa); 4) estimate the respondent burden of self-administration versus interviewer-administration for the different measures; and 5) estimate the English and Spanish language readability of the 4 generic HRQOL measures. This 48-month effort will involve two primary data collection activities. First, we propose to supplement the baseline data collection in the three centers (UCSD, UCLA, University of Wisconsin) of Project 2 (n =200 arthritis--hip replacement, n = 200 vision impairment--cataract extraction with lens replacement, n =200 heart failure--medication treatment) by conducting 600 telephone interviews. Second, we will collect data from 400 adult Hispanic patients (200 English-speaking and 200 Spanish-speaking) from two sites in Los Angeles: AltaMed Senior BuenaCare and Roybal Comprehensive Health Center. This project will provide essential information about the equivalence of SF-36, QWB, HUI, and EQ-5D data collected in different modes and language of administration. Results will enable researchers to decide whether it is appropriate to pool data by mode and language. In addition, the study will yield information that will allow estimates of responses in one mode of administration (e.g., self-administered) from the other (e.g., interviewer-administered). If the results show that the different modes of assessment are equivalent or at least predictable from one another, then this will allow greater flexibility in collecting data using different modes and mixed mode data collection. In addition, the study will provide important information about the readability of widely used generic HRQOL measures that can be useful in deciding the appropriateness of their use with lower-educated and less literate subgroups.
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0.945 |
2012 — 2016 |
Hays, Ronald Dale |
P30Activity Code Description: To support shared resources and facilities for categorical research by a number of investigators from different disciplines who provide a multidisciplinary approach to a joint research effort or from the same discipline who focus on a common research problem. The core grant is integrated with the center's component projects or program projects, though funded independently from them. This support, by providing more accessible resources, is expected to assure a greater productivity than from the separate projects and program projects. |
Analysis Core @ University of California Los Angeles
The primary mission of the UCLA/RCMAR/CHIME Analysis Core (AnC) is to provide comprehensive analytic support to CHIME pilot investigators. The CHIME AnC will advance measurement methodology and statistical as well as qualitative analyses for minority aging research, and promote the participation of minority elders in research. The specific aims of the Analysis Core are: Aim 1: To identify, catalogue and distribute culturally informed and scientifically valid epidemiological, behavioral, and social measurement tools and analysis methods and promote their use in aging research; Aim 2: To assist pilot investigators with use or modification of existing measures, and with the development of new epidemiological, behavioral, or social measurement tools for use in culturally diverse elderly populations; Aim 3: To provide comprehensive methodological and statistical support to CHIME pilot investigators including qualitative methods (e.g., focus groups and cognitive interviews), sampling, patient recruitment, power, and statistical analyses; Aim 4: To provide comprehensive support for secondary analyses of economic or genetic data that will lead to interventions addressing health disparities. The CHIME AnC has a diverse faculty of internationally-recognized experts drawn from UCLA, Charles R. Drew University of Medicine and Science, and RAND. Additional expertise will be available to pilot investigators through collaboration agreements with the UCLA Older American Independence Center (OAIC), the UCLA California Center for Population Research, the USC-UCLA Center of Biodemography and Population Health, the UCLA Clinical and Translational Science Institute (CTSI), the RAND Center for the Study of Aging, and the RAND Center for Population Health and Health Disparities.
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1 |
2018 — 2021 |
Hays, Ronald Dale |
P30Activity Code Description: To support shared resources and facilities for categorical research by a number of investigators from different disciplines who provide a multidisciplinary approach to a joint research effort or from the same discipline who focus on a common research problem. The core grant is integrated with the center's component projects or program projects, though funded independently from them. This support, by providing more accessible resources, is expected to assure a greater productivity than from the separate projects and program projects. |
Chime Analysis Core (Anc) @ University of California Los Angeles
Project Summary for the RCMAR CHIME Analysis Core The primary mission of the CHIME analysis core (AnC) is to provide data collection and analysis support to RCMAR Scientists and to promote new lines of investigation that will address our theme of ?Developing, Adapting and Evaluating Interventions to Improve the Health of Minority Elders?, which incorporates elements of two of the RFA areas of scientific focus: i) research aimed at understanding and modifying organizational or individual behaviors associated with positive and negative health outcomes in later life, including organizational and individual interventions in the health care system, and ii) research on factors that affect population aging, as well as the consequences of population aging.The three specific aims of the AnC are to: 1) Provide comprehensive methodological and statistical support to CHIME RCMAR Scientists including qualitative data methods (e.g., focus groups and cognitive interviews) and quantitative data methods for developing, implementing, analyzing, and disseminating organizational and individual behavioral interventions, 2) Provide exposure to state-of-the-science analytic methods and approaches for the analysis of secondary data to understand factors that affect population aging, particularly for minorities, 3) Assist RCMAR Scientists with use or modification of existing measures, or developing new behavioral or social measurement tools for use in mid- life or elderly populations, particularly those of low socio-economic status or other societal disadvantages. The AnC will connect RCMAR Scientists with the new Methods Centers at the RAND Pardee Graduate School, the online UCSF Implementation Science Curriculum, and a qualitative data analysis course led by AnC co- director Dr. Gery Ryan; each of which will support the development of research addressing both focus areas (i) and (ii). In addition, the AnC will provide support to all RCMAR Scientists in addressing identified measurement and methods issues, by matching Core and/or consulting faculty with RCMAR Scientists based on the specific methodologic expertise of the faculty and the needs of the pilot studies. The AnC will also provide assistance with data management and statistical and programming support as needed, in order to facilitate high-quality research adressing the Center theme.
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1 |