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High-probability grants
According to our matching algorithm, Alexxai V. Kravitz is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
2011 — 2012 |
Kravitz, Alexxai V |
F32Activity Code Description: To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in specified health-related areas. |
The Role of the Direct and Indirect Striatal Pathways in Movement and Learning @ J. David Gladstone Institutes
DESCRIPTION (provided by applicant): Many diseases, including Parkinson's disease, Huntington's disease, and drug addiction, have been linked to dysfunction in a brain system called the basal ganglia. Despite decades of research on this system, there are no long-term treatments or cures for these disorders. This proposal aims to use novel techniques to investigate the basal ganglia, and thereby identify novel strategies and insights for treating diseases of the basal ganglia. PUBLIC HEALTH RELEVANCE: Many diseases, including Parkinson's disease, Huntington's disease, and drug addiction, have been linked to dysfunction in a brain system called the basal ganglia. Despite decades of research on this system, there are no long-term treatments or cures for these disorders. This proposal aims to use novel techniques to investigate the basal ganglia, and thereby identify novel strategies and insights for treating diseases of the basal ganglia.
|
0.975 |
2013 — 2018 |
Kravitz, Alexxai V |
ZIAActivity Code Description: Undocumented code - click on the grant title for more information. |
Can Direct Pathway Stimulation Cause Addiction-Like Changes in Behavior? @ Diabetes, Digestive, Kidney Diseases
In this project, we will train mice to self-stimulate their direct pathway medium spiny neurons (dMSNs) using optogenetics. In prior work, we have found that mice find this behavior highly reinforcing. However, prior work gave mice at most 90 minutes of total training time. We plan to expand this by a factor of 100, giving the mice much more experience with this highly reinforcing behavior. We will examine behavioral changes in these mice, including assaying their motivation to receive stimulation, willingness to work for stimulation, and willingness to endure negative consequences to receive stimulation.
|
0.907 |