1981 — 1984 |
Tamarin, Robert Levy, Charles |
N/AActivity Code Description: No activity code was retrieved: click on the grant title for more information |
Determining Kinship in Voles (Microtus) With Radionuclides @ Trustees of Boston University |
1 |
1985 — 1989 |
Tamarin, Robert H |
S07Activity Code Description: To strengthen, balance, and stabilize Public Health Service supported biomedical and behavioral research programs at qualifying institutions through flexible funds, awarded on a formula basis, that permit grantee institutions to respond quickly and effectively to emerging needs and opportunities, to enhance creativity and innovation, to support pilot studies, and to improve research resources, both physical and human. |
Biomedical Research Support @ Boston University Medical Campus
health science research support; university;
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0.958 |
1985 — 1987 |
Tamarin, Robert H |
R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. |
Dispersal and Kinship in Vole Population Regulation @ Boston University Medical Campus
What are the causes of vole population cycles? What are the roles of dispersal, social behavior, and natural selection in controlling population processes in general? The research outlined in this proposal will seek to answer these questions by combining new techniques of study to test three major behavioral hypotheses of population regulation, specifically in voles, but applicable in animal populations in general. Since 1978 my students and I have developed a fence design that overcomes the "fence effect" by letting dispersers leave. We can use this design to trap a group of very highly motivated dispersers. In addition, this design will be used for future manipulations of vole populations. We have also developed a radionuclide-electrophoresis technique to determine relatedness of individual voles in the field. From this technique we can assess the social environment of individuals as well as the heritability of any measurable trait. Using these methods in meadow vole populations (Microtus pennsylvanicus) in eastern Massachusetts we can test three major behavioral hypotheses of population regulation: The polymorphic behavior hypothesis which predicts a high heritability of aggressive behavior in voles; The sociobiological hypothesis which predicts a change in the relatedness of neighboring individuals as density changes; and the outbreeding hypothesis which predicts that changes in density in vole populations will be accompanied by changes in heterozygosity which directly cause changes in aggression that lead to the vole cycle. The experimental design presented will provide the most comprehensive study of vole dispersal, heritability, and relatedness possible and will unambiguously and definitively test the above hypotheses. Understanding the causes of vole cycles will be important in controlling these and similar organisms when they are agricultural or public health pests.
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0.958 |
1986 |
Tamarin, Robert H |
R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. |
Dispersal and Kinship in Population Regulation @ Boston University Medical Campus |
0.958 |
1987 |
Tamarin, Robert H |
S15Activity Code Description: Undocumented code - click on the grant title for more information. |
Cryostat, Computer, &Scanning Spectrophotometer @ Boston University Medical Campus
biomedical equipment resource; spectrometry;
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0.958 |
1988 |
Tamarin, Robert H |
R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. |
Population Regulation, Dispersal and Kinship @ Boston University Medical Campus
What are the causes of vole population cycles? What are the roles of dispersal, social behavior, and natural selection in controlling population processes in general? The research outlined in this proposal will seek to answer these questions by combining new techniques of study to test three major behavioral hypotheses of population regulation, specifically in voles, but applicable in animal populations in general. Since 1978 my students and I have developed a fence design that overcomes the "fence effect" by letting dispersers leave. We can use this design to trap a group of very highly motivated dispersers. In addition, this design will be used for future manipulations of vole populations. We have also developed a radionuclide-electrophoresis technique to determine relatedness of individual voles in the field. From this technique we can assess the social environment of individuals as well as the heritability of any measurable trait. Using these methods in meadow vole populations (Microtus pennsylvanicus) in eastern Massachusetts we can test three major behavioral hypotheses of population regulation: The polymorphic behavior hypothesis which predicts a high heritability of aggressive behavior in voles; The sociobiological hypothesis which predicts a change in the relatedness of neighboring individuals as density changes; and the outbreeding hypothesis which predicts that changes in density in vole populations will be accompanied by changes in heterozygosity which directly cause changes in aggression that lead to the vole cycle. The experimental design presented will provide the most comprehensive study of vole dispersal, heritability, and relatedness possible and will unambiguously and definitively test the above hypotheses. Understanding the causes of vole cycles will be important in controlling these and similar organisms when they are agricultural or public health pests.
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0.958 |
1988 — 1989 |
Tamarin, Robert H |
S15Activity Code Description: Undocumented code - click on the grant title for more information. |
Small Instrumentation Program @ Boston University Medical Campus
biomedical equipment purchase;
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0.958 |
1990 — 1992 |
Tamarin, Robert Levy, Charles Tolan, Dean (co-PI) [⬀] |
N/AActivity Code Description: No activity code was retrieved: click on the grant title for more information |
Minisatellite Dna, Kinship, and Population Processes @ Trustees of Boston University
Voles are unique because of their central role in ecosystem food chains, the density cycles that many populations undergo, their potential to cause human health and agricultural problems, and their role as a general model of population regulation. Currently there is no explanation for the vole cycle of density but there is great interest in understanding this phenomenon from both the scientific and agricultural communities. In order to test possible mechanisms of population regulation, Dr. Tamarin and his colleagues have developed a technique to determine relatedness in field animals using radioactive isotopes and electrophoresis, a protein separation technique. Research in the past has resulted in estimates with confidence in maternity but reduced confidence in paternity because these estimates relied on electrophoresis that, due to limited marker genes, did not reveal sufficient variability. Recombinant DNA techniques, now available to overcome these problems, will be used to give near certain estimates of paternity.
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