Matthew A. Sills

Affiliations: 
1981-1984 Pharmacology University of Pennsylvania, Philadelphia, PA, United States 
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"Matthew Sills"
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Alan Frazer grad student 1981-1984 Penn
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Publications

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Cole AG, Bohnstedt AC, Paradkar V, et al. (2009) 2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 6788-92
Zhang JH, Wu X, Sills MA. (2005) Probing the primary screening efficiency by multiple replicate testing: a quantitative analysis of hit confirmation and false screening results of a biochemical assay. Journal of Biomolecular Screening. 10: 695-704
Wu X, Sills MA, Zhang JH. (2005) Further comparison of primary hit identification by different assay technologies and effects of assay measurement variability. Journal of Biomolecular Screening. 10: 581-9
Wu X, Glickman JF, Bowen BR, et al. (2003) Comparison of assay technologies for a nuclear receptor assay screen reveals differences in the sets of identified functional antagonists. Journal of Biomolecular Screening. 8: 381-92
Sills MA, Weiss D, Pham Q, et al. (2002) Comparison of assay technologies for a tyrosine kinase assay generates different results in high throughput screening. Journal of Biomolecular Screening. 7: 191-214
Glickman JF, Wu X, Mercuri R, et al. (2002) A comparison of ALPHAscreen, TR-FRET, and TRF as assay methods for FXR nuclear receptors Journal of Biomolecular Screening. 7: 3-10
Peppard JV, Loo P, Sills MA, et al. (2001) The discovery and characterization of an interleukin 6 cytokine family antagonist protein from a marine sponge, Callyspongia sp. Advances in Experimental Medicine and Biology. 484: 77-87
Killday KB, Yarwood D, Sills MA, et al. (2001) Microxine, a new cdc2 kinase inhibitor from the Australian marine sponge Microxina species. Journal of Natural Products. 64: 525-6
Bold G, Altmann KH, Frei J, et al. (2000) New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis Journal of Medicinal Chemistry. 43: 2310-2323
Wu JJ, Yarwood DR, Pham Q, et al. (2000) Identification of a high-affinity anti-phosphoserine antibody for the development of a homogeneous fluorescence polarization assay of protein kinase C. Journal of Biomolecular Screening. 5: 23-30
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