Haley E Melikian, Ph.D.

Affiliations: 
1991-1995 Neuroscience Emory University, Atlanta, GA 
 1997-2000 Neurobiology Harvard Medical School, Boston, MA, United States 
 2001- Brudnick Neuropsychiatric Research Institute University of Massachussetts Medical School, Worcester, MA, United States 
 2017- Neurbiology University of Massachussetts Medical School, Worcester, MA, United States 
Area:
Dopamine Transporters, psychostimulant addiction
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"Haley Melikian"
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Publications

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Kearney P, Zhang Y, Tan Y, et al. (2023) Rit2 silencing in dopamine neurons drives a progressive Parkinsonian phenotype. Research Square
Kearney PJ, Zhang Y, Tan Y, et al. (2023) Rit2 silencing in dopamine neurons drives a progressive Parkinsonian phenotype. Biorxiv : the Preprint Server For Biology
Kearney PJ, Bolden NC, Kahuno E, et al. (2023) Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function. The Journal of Biological Chemistry. 102900
Fagan RR, Kearney PJ, Luethi D, et al. (2021) Dopaminergic Ric GTPase activity impacts amphetamine sensitivity and sleep quality in a dopamine transporter-dependent manner in Drosophila melanogaster. Molecular Psychiatry
Fagan RR, Kearney PJ, Melikian HE. (2020) In Situ Regulated Dopamine Transporter Trafficking: There's No Place Like Home. Neurochemical Research
Fagan RR, Kearney PJ, Sweeney CG, et al. (2020) Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact. The Journal of Biological Chemistry
Sweeney CG, Kearney PJ, Fagan RR, et al. (2019) Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Wu S, Fagan RR, Uttamapinant C, et al. (2017) The Dopamine Transporter Recycles Via A Retromer-Dependent Post-Endocytic Mechanism: Tracking Studies Using A Novel Fluorophore-Coupling Approach. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Sweeney CG, Tremblay BP, Stockner T, et al. (2016) Dopamine Transporter Amino- and Carboxy-Termini Synergistically Contribute to Substrate and Inhibitor Affinities. The Journal of Biological Chemistry
Wu S, Bellve KD, Fogarty KE, et al. (2015) Ack1 is a dopamine transporter endocytic brake that rescues a trafficking-dysregulated ADHD coding variant. Proceedings of the National Academy of Sciences of the United States of America
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