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Haley E Melikian, Ph.D.

Affiliations: 
1991-1995 Neuroscience Emory University, Atlanta, GA 
 1997-2000 Neurobiology Harvard Medical School, Boston, MA, United States 
 2001- Brudnick Neuropsychiatric Research Institute University of Massachussetts Medical School, Worcester, MA, United States 
 2017- Neurbiology University of Massachussetts Medical School, Worcester, MA, United States 
Area:
Dopamine Transporters, psychostimulant addiction
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Parents

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Randy D. Blakely grad student 1990-1995 University of Massachusetts Chan Medical School
Stephen T. Warren post-doc 1995-1997 Emory University School of Medicine
Kathleen M. Buckley post-doc 1997-2000 Harvard Medical School

Children

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Patrick J. Kearney grad student 2015- UMass Med School
NIcholas Bolden grad student 2018- UMass Med School
Ekaterina Boudanova grad student 2004-2008 UMass Med School
Luke Gabriel grad student 2008-2014 UMass Med School
Sijia Wu grad student 2011-2017 UMass Med School
Carolyn G Sweeney grad student 2012-2018 UMass Med School
Rita R Fagan grad student 2014-2020 UMass Med School
Lindsey A. Smith post-doc 2018- UMass Med School
Merewyn Loder post-doc 2001-2004 UMass Med School
Allyson Marshall post-doc 2014-2016 UMass Med School
Joanna Hawryluk post-doc 2016-2017 UMass Med School

Collaborators

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Andrew Tapper collaborator 2012- UMass Med School
Patrick Emery-Le collaborator 2014- UMass Med School
Gilles E. Martin collaborator 2017- UMass Med School
BETA: Related publications

Publications

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Bolden NC, Pavchinskiy RG, Melikian HE. (2024) Dopamine transporter endocytic trafficking: Neuronal mechanisms and potential impact on DA-dependent behaviors. Journal of Neurochemistry. 169: e16284
Kearney PJ, Zhang Y, Liang M, et al. (2024) Silencing Parkinson's risk allele Rit2 sex-specifically compromises motor function and dopamine neuron viability. Npj Parkinson's Disease. 10: 41
Kearney P, Zhang Y, Tan Y, et al. (2023) Rit2 silencing in dopamine neurons drives a progressive Parkinsonian phenotype. Research Square
Kearney PJ, Zhang Y, Tan Y, et al. (2023) Rit2 silencing in dopamine neurons drives a progressive Parkinsonian phenotype. Biorxiv : the Preprint Server For Biology
Kearney PJ, Bolden NC, Kahuno E, et al. (2023) Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function. The Journal of Biological Chemistry. 102900
Fagan RR, Kearney PJ, Luethi D, et al. (2021) Dopaminergic Ric GTPase activity impacts amphetamine sensitivity and sleep quality in a dopamine transporter-dependent manner in Drosophila melanogaster. Molecular Psychiatry
Fagan RR, Kearney PJ, Melikian HE. (2020) In Situ Regulated Dopamine Transporter Trafficking: There's No Place Like Home. Neurochemical Research
Fagan RR, Kearney PJ, Sweeney CG, et al. (2020) Dopamine transporter trafficking and Rit2 GTPase: Mechanism of action and in vivo impact. The Journal of Biological Chemistry
Sweeney CG, Kearney PJ, Fagan RR, et al. (2019) Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Wu S, Fagan RR, Uttamapinant C, et al. (2017) The Dopamine Transporter Recycles Via A Retromer-Dependent Post-Endocytic Mechanism: Tracking Studies Using A Novel Fluorophore-Coupling Approach. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
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