Karen S. Wilcox

University of Utah, Salt Lake City, UT 
basic mechanisms of epilepsy, anticonvulsant drug development
"Karen Wilcox"
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West PJ, Thomson K, Billingsley P, et al. (2021) Spontaneous recurrent seizures in an intra-amygdala kainate microinjection model of temporal lobe epilepsy are differentially sensitive to antiseizure drugs. Experimental Neurology. 349: 113954
Barker-Haliski M, Knox K, Zierath D, et al. (2021) Development of an antiepileptogenesis drug screening platform: Effects of everolimus and phenobarbital. Epilepsia
Galanopoulou AS, Löscher W, Lubbers L, et al. (2021) Antiepileptogenesis and disease modification: Progress, challenges, and the path forward-Report of the Preclinical Working Group of the 2018 NINDS-sponsored antiepileptogenesis and disease modification workshop. Epilepsia Open
Pernici CD, Mensah JA, Dahle EJ, et al. (2021) Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program. Epilepsia
Thomson KE, West PJ, Metcalf CS, et al. (2021) Response: Usefulness of the post-kainate spontaneous recurrent seizure model for screening for antiseizure and for neuroprotective effects. Epilepsia
Fumeaux NF, Ebrahim S, Coughlin BF, et al. (2020) Accurate detection of spontaneous seizures using a generalized linear model with external validation. Epilepsia
Thomson KE, Metcalf CS, Newell TG, et al. (2020) Evaluation of subchronic administration of antiseizure drugs in spontaneously seizing rats. Epilepsia
Li X, Himes RA, Prosser LC, et al. (2020) Discovery of the first Vitamin K analog as a potential treatment of pharmacoresistant seizures. Journal of Medicinal Chemistry
Clarkson C, Smeal RM, Hasenoehrl MG, et al. (2020) Ultrastructural and functional changes at the tripartite synapse during epileptogenesis in a model of temporal lobe epilepsy. Experimental Neurology. 113196
Wilcox KS, West PJ, Metcalf CS. (2019) The Current Approach of the Epilepsy Therapy Screening Program Contract Site for Identifying Improved Therapies for the Treatment of Pharmacoresistant Seizures in Epilepsy. Neuropharmacology. 107811
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