Shawn C. Burgess, Ph.D.

Affiliations: 
1995-2000 Chemistry University of Texas at Dallas, Richardson, TX, United States 
 2000- Center for Human Nutrition and Department of Pharmacology University of Texas Southwestern Medical Center at Dallas, Dallas, TX, United States 
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A. Dean Sherry grad student 2000 UT Dallas
 (Practicum Three, August 2000. Novel applications of carbon-13 indirect detection NMR to metabolic tracer studies in small tissue samples. Practicum Two, December 1998. Proton and platinum-195 NMR spectroscopic characterization of the products formed in re)
Craig R Malloy post-doc
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Publications

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Deja S, Fletcher JA, Kim CW, et al. (2024) Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability. Cell Metabolism
Yiew NKH, Deja S, Ferguson D, et al. (2023) Effects of hepatic mitochondrial pyruvate carrier deficiency on lipogenesis and gluconeogenesis in mice. Iscience. 26: 108196
Fu X, Fletcher JA, Deja S, et al. (2023) Persistent fasting lipogenesis links impaired ketogenesis with citrate synthesis in humans with non-alcoholic fatty liver. The Journal of Clinical Investigation
Yiew NKH, Ferguson D, Cho K, et al. (2023) Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and glycerol-mediated gluconeogenesis in mice. Biorxiv : the Preprint Server For Biology
Martino MR, Gutiérrez-Aguilar M, Yiew NKH, et al. (2022) Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids. Cell Reports. 39: 110733
Deja S, Duarte J, Fletcher JA, et al. (2020) 368-OR: Activation of Hepatic Gluconeogenesis Is Required to Suppress DNL and Stimulate Ketogenesis during Fasting Diabetes. 69
Deja S, Fletcher JA, Kucejova B, et al. (2020) 204-OR: Inhibition of Hepatic ACC on a High-Fat Diet Results in Hyperglycemia and Hepatomegaly Due to Excess Energy Generation Diabetes. 69
Inigo MMR, Deja S, Kucejova B, et al. (2020) 1809-P: Liver Pyruvate Carboxylase Knockout Mice Suggest Noncanonical Sources of Acetyl-CoA for Hepatic Lipid Synthesis Diabetes. 69
Kucejova B, Deja S, Duarte J, et al. (2020) 1721-P: In Vivo Effect of Perturbations in Hepatic Insulin Signaling on the Synthesis and Export of De Novo Synthesized Fatty Acids and Triglycerides Diabetes. 69
Deja S, Fu X, Fletcher JA, et al. (2019) Simultaneous tracers and a unified model of positional and mass isotopomers for quantification of metabolic flux in liver. Metabolic Engineering
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