Jean-Pierre Jaffrezou

1992- Stanford University School of Medicine, Palo Alto, CA, United States 
"Jean-Pierre Jaffrezou"
Mean distance: 20.07 (cluster 32)
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Charruyer A, Jean C, Colomba A, et al. (2007) PKCzeta protects against UV-C-induced apoptosis by inhibiting acid sphingomyelinase-dependent ceramide production. The Biochemical Journal. 405: 77-83
Charruyer A, Grazide S, Bezombes C, et al. (2005) UV-C light induces raft-associated acid sphingomyelinase and JNK activation and translocation independently on a nuclear signal. The Journal of Biological Chemistry. 280: 19196-204
Jaffrezou JP, Laurent G. (2004) Ceramide : A New Target in Anticancer Research? Bulletin Du Cancer. 91: E133-61
Dumontet C, Jaffrezou JP, Tsuchiya E, et al. (2004) Resistance to microtubule-targeted cytotoxins in a K562 leukemia cell variant associated with altered tubulin expression and polymerization. Bulletin Du Cancer. 91: E81-112
Bezombes C, Grazide S, Garret C, et al. (2004) Rituximab antiproliferative effect in B-lymphoma cells is associated with acid-sphingomyelinase activation in raft microdomains. Blood. 104: 1166-73
Pongracz J, Parnell S, Anderson G, et al. (2003) Con A activates an Akt/PKB dependent survival mechanism to modulate TCR induced cell death in double positive thymocytes. Molecular Immunology. 39: 1013-23
Bezombes C, de Thonel A, Apostolou A, et al. (2002) Overexpression of protein kinase Czeta confers protection against antileukemic drugs by inhibiting the redox-dependent sphingomyelinase activation. Molecular Pharmacology. 62: 1446-55
Maddens S, Charruyer A, Plo I, et al. (2002) Kit signaling inhibits the sphingomyelin-ceramide pathway through PLC gamma 1: implication in stem cell factor radioprotective effect. Blood. 100: 1294-301
Bruno AP, Laurent G, Demur C, et al. (2001) Genotypical instability in undifferentiated cells: precursors for environmental adaptability? Cell Death and Differentiation. 8: 436-7
Laurent G, Jaffrézou JP. (2001) Signaling pathways activated by daunorubicin. Blood. 98: 913-24
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