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Joseph A. Burlison, MS, Ph.D.

Affiliations: 
2011- J. G. Brown Cancer Center University of Louisville, Louisville, KY, United States 
Area:
Medicinal Chemistry
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"Joseph Burlison"
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Parents

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David G. J. Young grad student 1999-2005 University of Tennessee
 (Studies directed toward the synthesis of acylated phloroglucinols.)
Brian Blagg post-doc 2005-2007 University of Kansas

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Publications

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McCready J, Wong DS, Burlison JA, et al. (2014) An Impermeant Ganetespib Analog Inhibits Extracellular Hsp90-Mediated Cancer Cell Migration that Involves Lysyl Oxidase 2-like Protein. Cancers. 6: 1031-46
Zhao G, Zhu Y, Eno CO, et al. (2014) Activation of the proapoptotic Bcl-2 protein bax by a small molecule induces tumor cell apoptosis Molecular and Cellular Biology. 34: 1198-1207
Donnelly AC, Mays JR, Burlison JA, et al. (2008) The design, synthesis, and evaluation of coumarin ring derivatives of the novobiocin scaffold that exhibit antiproliferative activity. The Journal of Organic Chemistry. 73: 8901-20
Burlison JA, Avila C, Vielhauer G, et al. (2008) Development of novobiocin analogues that manifest anti-proliferative activity against several cancer cell lines. The Journal of Organic Chemistry. 73: 2130-7
Bishop SC, Burlison JA, Blagg BS. (2007) Hsp90: a novel target for the disruption of multiple signaling cascades. Current Cancer Drug Targets. 7: 369-88
Ansar S, Burlison JA, Hadden MK, et al. (2007) A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity. Bioorganic & Medicinal Chemistry Letters. 17: 1984-90
Burlison JA, Neckers L, Smith AB, et al. (2006) Novobiocin: redesigning a DNA gyrase inhibitor for selective inhibition of hsp90. Journal of the American Chemical Society. 128: 15529-36
Burlison JA, Blagg BS. (2006) Synthesis and evaluation of coumermycin A1 analogues that inhibit the Hsp90 protein folding machinery. Organic Letters. 8: 4855-8
Young DG, Burlison JA, Peters U. (2003) A general approach to medium ring alkynes by using metathesis of cobalt hexacarbonyl containing dienes. The Journal of Organic Chemistry. 68: 3494-7
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