Christine Marie Dieckhaus

Affiliations: 
2001 University of Virginia, Charlottesville, VA 
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Timothy L. Macdonald grad student 2001 UVA
 (The metabolism and idiosyncratic reactions of the anti-epileptic drug felbamate.)
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Deveau AM, Labroli MA, Dieckhaus CM, et al. (2010) ChemInform Abstract: Synthesis of Amino-Acid Functionalized β-Carbolines as Topoisomerase II Inhibitors. Cheminform. 32: no-no
Jain HD, Zhang C, Zhou S, et al. (2008) Synthesis and structure-activity relationship studies on tryprostatin A, an inhibitor of breast cancer resistance protein. Bioorganic & Medicinal Chemistry. 16: 4626-51
Kapetanovic IM, Torchin CD, Strong JM, et al. (2002) Reactivity of atropaldehyde, a felbamate metabolite in human liver tissue in vitro Chemico-Biological Interactions. 142: 119-134
Dieckhaus CM, Thompson CD, Roller SG, et al. (2002) Mechanisms of idiosyncratic drug reactions: The case of felbamate Chemico-Biological Interactions. 142: 99-117
Roller SG, Dieckhaus CM, Santos WL, et al. (2002) Interaction between human serum albumin and the felbamate metabolites 4-Hydroxy-5-phenyl-[1,3]oxazinan-2-one and 2-phenylpropenal. Chemical Research in Toxicology. 15: 815-24
Zhao S, Smith KS, Deveau AM, et al. (2002) Biological activity of the tryprostatins and their diastereomers on human carcinoma cell lines. Journal of Medicinal Chemistry. 45: 1559-62
Roller SG, Dieckhaus CM, Santos WL, et al. (2002) Interaction between human serum albumin and the felbamate metabolites 4-hydroxy-5-phenyl-[1,3]oxazinan-2-one and 2-phenylpropenal Chemical Research in Toxicology. 15: 815-824
Dieckhaus CM, Santos WL, Sofia RD, et al. (2001) The chemistry, toxicology, and identification in rat and human urine of 4-hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one: A reactive metabolite in felbamate bioactivation Chemical Research in Toxicology. 14: 958-964
Deveau AM, Labroli MA, Dieckhaus CM, et al. (2001) The synthesis of amino-acid functionalized beta-carbolines as topoisomerase II inhibitors. Bioorganic & Medicinal Chemistry Letters. 11: 1251-5
Dieckhaus CM, Roller SG, Santos WL, et al. (2001) Role of glutathione S-transferases A1-1, M1-1, and P1-1 in the detoxification of 2-phenylpropenal, a reactive felbamate metabolite Chemical Research in Toxicology. 14: 511-516
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