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Peter N. R. Usherwood, Ph.D.

Affiliations: 
1986- Chemistry University of Nottingham, Nottingham, England, United Kingdom 
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"Peter Usherwood"
Mean distance: 39813
 
Cross-listing: Entomology Tree - Physiology Academic Tree

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Parents

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Charles Maurice Yonge research assistant (Marine Mammal Science)
Graham Hoyle grad student 1962 University of Glasgow (Neurotree)
 (Ph.D.: The nature of slow and fast contractions in the skeletal muscles of insects)

Children

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Robin C. Brace research assistant Nottingham (Evolution Tree)
Donald L. J. Quicke grad student 1981 Nottingham (Entomology Tree)

Collaborators

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Koji Nakanishi collaborator 1986-1988 Nottingham
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Publications

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Olsen CA, Mellor IR, Wellendorph P, et al. (2006) Tuning wasp toxin structure for nicotinic receptor antagonism: cyclohexylalanine-containing analogues as potent and voltage-dependent blockers. Chemmedchem. 1: 303-5
Olsen C, Mellor I, Wellendorph P, et al. (2006) Cover Picture: Tuning Wasp Toxin Structure for Nicotinic Receptor Antagonism: Cyclohexylalanine-Containing Analogues as Potent and Voltage-Dependent Blockers (ChemMedChem 3/2006) Chemmedchem. 1: 281-281
Bolshakov KV, Kim KH, Potapjeva NN, et al. (2005) Design of antagonists for NMDA and AMPA receptors. Neuropharmacology. 49: 144-55
Tikhonov DB, Mellor IR, Usherwood PN. (2004) Modeling noncompetitive antagonism of a nicotinic acetylcholine receptor. Biophysical Journal. 87: 159-70
Mellor IR, Usherwood PN. (2004) Targeting ionotropic receptors with polyamine-containing toxins. Toxicon : Official Journal of the International Society On Toxinology. 43: 493-508
Brier TJ, Mellor IR, Tikhonov DB, et al. (2003) Contrasting actions of philanthotoxin-343 and philanthotoxin-(12) on human muscle nicotinic acetylcholine receptors. Molecular Pharmacology. 64: 954-64
Mellor IR, Brier TJ, Pluteanu F, et al. (2003) Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors. Neuropharmacology. 44: 70-80
Tikhonov DB, Mellor JR, Usherwood PN, et al. (2002) Modeling of the pore domain of the GLUR1 channel: homology with K+ channel and binding of channel blockers. Biophysical Journal. 82: 1884-93
Strømgaard K, Brier TJ, Andersen K, et al. (2000) Solid-phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues. Journal of Medicinal Chemistry. 43: 4526-33
Usherwood PN. (2000) Natural and synthetic polyamines: modulators of signalling proteins. Farmaco (Società Chimica Italiana : 1989). 55: 202-5
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