Lace M. Riggs, PhD

Affiliations: 
2012-2016 Department of Psychology California State University, San Bernardino 
 2016-2021 Program in Neuroscience University of Maryland School of Medicine, Baltimore, MD, United States 
 2021- Department of Brain and Cognitive Sciences McGovern Institute for Brain Research at MIT 
Area:
Neuroscience, Physiology
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"Lace Riggs"
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Publications

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Riggs LM, Pereira EFR, Thompson SM, et al. (2023) cAMP-dependent protein kinase signaling is required for ()-hydroxynorketamine to potentiate hippocampal glutamatergic transmission. Journal of Neurophysiology
Riggs LM, Thompson SM, Gould TD. (2022) (2R,6R)-hydroxynorketamine rapidly potentiates optically-evoked Schaffer collateral synaptic activity. Neuropharmacology. 214: 109153
Hasin N, Riggs LM, Shekhtman T, et al. (2022) Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder. Molecular Psychiatry
Highland JN, Morris PJ, Konrath KM, et al. (2022) Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (26)- and (5)-Methyl-(26)-hydroxynorketamines. Acs Chemical Neuroscience. 13: 510-523
Hess EM, Riggs LM, Michaelides M, et al. (2021) Mechanisms of Ketamine and its Metabolites as Antidepressants. Biochemical Pharmacology. 114892
Riggs LM, An X, Pereira EFR, et al. (2021) (R,S)-ketamine and (2R,6R)-hydroxynorketamine differentially affect memory as a function of dosing frequency. Translational Psychiatry. 11: 583
Highland JN, Zanos P, Riggs LM, et al. (2021) Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications. Pharmacological Reviews. 73: 763-791
Riggs LM, Gould TD. (2021) Ketamine and the Future of Rapid-Acting Antidepressants. Annual Review of Clinical Psychology
Wang AQ, Konrath KM, Highland JN, et al. (2020) P199 - HILIC UPLC-MS/MS methods for the assessment of hydroxynorketamines pharmacokinetics in mouse plasma and brain Drug Metabolism and Pharmacokinetics. 35
Riggs LM, Aracava Y, Zanos P, et al. (2019) (2R,6R)-hydroxynorketamine acts through a synapse-specific presynaptic mechanism to rapidly potentiate hippocampal glutamatergic transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
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