Lace M. Riggs, PhD

Affiliations: 
2012-2016 Department of Psychology California State University, San Bernardino 
 2016-2021 Program in Neuroscience University of Maryland School of Medicine, Baltimore, MD, United States 
 2021- Department of Brain and Cognitive Sciences McGovern Institute for Brain Research at MIT 
Area:
Neuroscience, Physiology
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"Lace Riggs"
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Publications

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Highland JN, Morris PJ, Konrath KM, et al. (2022) Hydroxynorketamine Pharmacokinetics and Antidepressant Behavioral Effects of (26)- and (5)-Methyl-(26)-hydroxynorketamines. Acs Chemical Neuroscience. 13: 510-523
Hess EM, Riggs LM, Michaelides M, et al. (2021) Mechanisms of Ketamine and its Metabolites as Antidepressants. Biochemical Pharmacology. 114892
Riggs LM, An X, Pereira EFR, et al. (2021) (R,S)-ketamine and (2R,6R)-hydroxynorketamine differentially affect memory as a function of dosing frequency. Translational Psychiatry. 11: 583
Highland JN, Zanos P, Riggs LM, et al. (2021) Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications. Pharmacological Reviews. 73: 763-791
Riggs LM, Gould TD. (2021) Ketamine and the Future of Rapid-Acting Antidepressants. Annual Review of Clinical Psychology
Wang AQ, Konrath KM, Highland JN, et al. (2020) P199 - HILIC UPLC-MS/MS methods for the assessment of hydroxynorketamines pharmacokinetics in mouse plasma and brain Drug Metabolism and Pharmacokinetics. 35
Riggs LM, Aracava Y, Zanos P, et al. (2019) (2R,6R)-hydroxynorketamine acts through a synapse-specific presynaptic mechanism to rapidly potentiate hippocampal glutamatergic transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Zanos P, Moaddel R, Morris PJ, et al. (2018) Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms. Pharmacological Reviews. 70: 621-660
Iñiguez SD, Flores-Ramirez FJ, Riggs LM, et al. (2017) Vicarious Social Defeat Stress Induces Depression-Related Outcomes in Female Mice. Biological Psychiatry
Iñiguez SD, Aubry A, Riggs LM, et al. (2016) Social defeat stress induces depression-like behavior and alters spine morphology in the hippocampus of adolescent male C57BL/6 mice. Neurobiology of Stress. 5: 54-64
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