Fred J. Sigworth

Yale University, New Haven, CT 
Ion channels
"Fred Sigworth"
Mean distance: 12.73 (cluster 46)
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Mnatsakanyan N, Llaguno MC, Yang Y, et al. (2019) A mitochondrial megachannel resides in monomeric FF ATP synthase. Nature Communications. 10: 5823
Jensen KH, Brandt SS, Shigematsu H, et al. (2016) Statistical Modeling and Removal of Lipid Membrane Projections for Cryo-EM Structure Determination of Reconstituted Membrane Proteins. Journal of Structural Biology
Singh SK, Sigworth FJ. (2015) Cryo-EM: Spinning the Micelles Away. Structure (London, England : 1993). 23: 1561
Tagare HD, Kucukelbir A, Sigworth FJ, et al. (2015) Directly reconstructing principal components of heterogeneous particles from cryo-EM images. Journal of Structural Biology
Dvornek NC, Sigworth FJ, Tagare HD. (2015) SubspaceEM: A fast maximum-a-posteriori algorithm for cryo-EM single particle reconstruction. Journal of Structural Biology. 190: 200-14
Liu Y, Sigworth FJ. (2014) Automatic cryo-EM particle selection for membrane proteins in spherical liposomes. Journal of Structural Biology. 185: 295-302
Kucukelbir A, Sigworth FJ, Tagare HD. (2014) Quantifying the local resolution of cryo-EM density maps. Nature Methods. 11: 63-5
Dongsoo Kim, Goldstein B, Wei Tang, et al. (2013) Noise analysis and performance comparison of low current measurement systems for biomedical applications. Ieee Transactions On Biomedical Circuits and Systems. 7: 52-62
Shigematsu H, Sigworth FJ. (2013) Noise models and cryo-EM drift correction with a direct-electron camera. Ultramicroscopy. 131: 61-9
Miranda P, Contreras JE, Plested AJ, et al. (2013) State-dependent FRET reports calcium- and voltage-dependent gating-ring motions in BK channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 5217-22
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