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Fred J. Sigworth

Affiliations: 
Yale University, New Haven, CT 
Area:
Ion channels
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"Fred Sigworth"
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Parents

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Charles F. Stevens grad student Yale
Erwin Neher post-doc Max-Planck-Institut für biophysikalische Chemie

Children

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Puey Ounjai grad student Yale
Nathan Schoppa grad student Yale
Jie Zheng grad student Yale
Leon D. Islas grad student 2000 Yale
Qiu-Xing Jiang grad student 2002 Yale
Theodore R. Cummins grad student 2002-2006 Indiana University School of Medicine
Pujitha A. Weerakoon grad student 2009 Yale
Andrew C. Barthel grad student 2012 Yale
Teresa Giraldez post-doc 2002-2005 Yale School of Medicine

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Publications

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Wu Y, Yan Y, Yang Y, et al. (2023) Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting. Biorxiv : the Preprint Server For Biology
Islas LD, Sigworth F. (2020) Decision letter: Top-down machine learning approach for high-throughput single-molecule analysis Elife
Mnatsakanyan N, Llaguno MC, Yang Y, et al. (2019) A mitochondrial megachannel resides in monomeric FF ATP synthase. Nature Communications. 10: 5823
Toombes G, Jiang Y, Sigworth F. (2019) Decision letter: Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology Elife
Sigworth F, Trimmer JS. (2019) Decision letter: The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier Elife
Shigematsu H, Yang Y, Yan Y, et al. (2019) Cryo-EM Imaging of Kv1.2 Channels with Membrane Potential Applied Biophysical Journal. 116
Bai JP, Moeini-Naghani I, Zhong S, et al. (2017) Current carried by the Slc26 family member prestin does not flow through the transporter pathway. Scientific Reports. 7: 46619
Shigematsu H, Yang Y, Yan Y, et al. (2017) Cryo-EM Structure of KV1.2 Channels in Liposomes Biophysical Journal. 112
Jensen KH, Brandt SS, Shigematsu H, et al. (2016) Statistical Modeling and Removal of Lipid Membrane Projections for Cryo-EM Structure Determination of Reconstituted Membrane Proteins. Journal of Structural Biology
Dvornek NC, Sigworth FJ, Tagare HD. (2015) SubspaceEM: A fast maximum-a-posteriori algorithm for cryo-EM single particle reconstruction. Journal of Structural Biology. 190: 200-14
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