Amy Tam, Ph.D.

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
s.cerevisiae, membrane biology, ABC transporters, protein degradation mechanisms
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"Amy Tam"
Mean distance: 21373.2 (cluster 53)
 

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Susan Michaelis grad student 2000 Johns Hopkins
 (Role of Ste24p in CaaX processing and N-terminal proteolysis of yeast a-factor.)
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Publications

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Tam A, Schmidt WK, Michaelis S. (2001) The multispanning membrane protein Ste24p catalyzes CAAX proteolysis and NH2-terminal processing of the yeast a-factor precursor. The Journal of Biological Chemistry. 276: 46798-806
Leung GK, Schmidt WK, Bergo MO, et al. (2001) Biochemical studies of Zmpste24-deficient mice. The Journal of Biological Chemistry. 276: 29051-8
Schmidt WK, Tam A, Michaelis S. (2000) Reconstitution of the Ste24p-dependent N-terminal proteolytic step in yeast a-factor biogenesis. The Journal of Biological Chemistry. 275: 6227-33
Loayza D, Tam A, Schmidt WK, et al. (1998) Ste6p mutants defective in exit from the endoplasmic reticulum (ER) reveal aspects of an ER quality control pathway in Saccharomyces cerevisiae. Molecular Biology of the Cell. 9: 2767-84
Schmidt WK, Tam A, Fujimura-Kamada K, et al. (1998) Endoplasmic reticulum membrane localization of Rce1p and Ste24p, yeast proteases involved in carboxyl-terminal CAAX protein processing and amino-terminal a-factor cleavage. Proceedings of the National Academy of Sciences of the United States of America. 95: 11175-80
Tam A, Nouvet FJ, Fujimura-Kamada K, et al. (1998) Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing. The Journal of Cell Biology. 142: 635-49
Geller D, Taglicht D, Edgar R, et al. (1996) Comparative topology studies in Saccharomyces cerevisiae and in Escherichia coli. The N-terminal half of the yeast ABC protein Ste6. The Journal of Biological Chemistry. 271: 13746-53
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