James E. East, Ph.D.
Affiliations: | University of Virginia, Charlottesville, VA |
Area:
Bioorganic and Synthetic Organic ChemistryGoogle:
"James East"Mean distance: 8.25 | S | N | B | C | P |
Parents
Sign in to add mentor| Timothy L. Macdonald | grad student | 2011 | UVA | |
| (Small Molecule Modulation of the Lysophosphatidic Acid Pathway.) | ||||
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Publications
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| Murphy A, Solomons J, Risby P, et al. (2022) Germline variant testing in Serrated Polyposis Syndrome. Journal of Gastroenterology and Hepatology |
| Curtius K, Kabir M, Al Bakir I, et al. (2021) Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool. Gut |
| Tiper IV, East JE, Subrahmanyam PB, et al. (2016) Sphingosine 1-phosphate signaling impacts lymphocyte migration, inflammation, and infection. Pathogens and Disease |
| Sun W, Wang Y, East JE, et al. (2015) Invariant natural killer T cells generated from human adult hematopoietic stem-progenitor cells are poly-functional. Cytokine. 72: 48-57 |
| East JE, Kennedy AJ, Webb TJ. (2014) Raising the roof: the preferential pharmacological stimulation of Th1 and th2 responses mediated by NKT cells. Medicinal Research Reviews. 34: 45-76 |
| East JE, Macdonald TL. (2012) Cost-effective and Large-scale synthesis of 16:0 Lysophosphatidic Acid. Synthetic Communications. 42: 3614-3618 |
| East JE, MacDonald TL. (2012) Cost-effective and large-scale synthesis of 16:0 lysophosphatidic acid Synthetic Communications. 42: 3614-3619 |
| East JE, Carter KM, Kennedy PC, et al. (2011) Development of a phosphatase-resistant, L-tyrosine derived LPA1/LPA3 dual antagonist. Medchemcomm. 2: 325-330 |
| Kennedy AJ, Mathews TP, Kharel Y, et al. (2011) Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells. Journal of Medicinal Chemistry. 54: 3524-48 |
| East JE, Kennedy AJ, Tomsig JL, et al. (2010) Synthesis and structure-activity relationships of tyrosine-based inhibitors of autotaxin (ATX). Bioorganic & Medicinal Chemistry Letters. 20: 7132-6 |