Daniel Basilio, Ph.D.

Facultad de Ciencias Universidad de Chile, Santiago, Región Metropolitana, Chile 
Biophysics of Membrane Transport
"Daniel Basilio"

My main intellectual fascination is the phenomenon of electricity in living things. Towards a better understanding of this subject, I have been studying molecular mechanisms of membrane proteins involved in ionic transport in biological membranes.

Mean distance: 15.12 (cluster 16)
Cross-listing: Chemistry Tree


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Michael V. Bennett research assistant 2004-2005 Albert Einstein
Alan Finkelstein grad student 2005-2011 Yeshiva University
 (Molecular mechanisms of protein transport through the anthrax toxin channel.)
Alessio Accardi post-doc 2011-2014 Weill Cornell Medical College


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Francisco Bezanilla collaborator
Miguel Holmgren collaborator
BETA: Related publications


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Mathur C, Johnson KR, Tong BA, et al. (2018) Demonstration of ion channel synthesis by isolated squid giant axon provides functional evidence for localized axonal membrane protein translation. Scientific Reports. 8: 2207
Vien M, Basilio D, Leisle L, et al. (2017) Probing the conformation of a conserved glutamic acid within the Cl(-) pathway of a CLC H(+)/Cl(-) exchanger. The Journal of General Physiology
Castillo JP, Rui H, Basilio D, et al. (2015) Mechanism of potassium ion uptake by the Na(+)/K(+)-ATPase. Nature Communications. 6: 7622
Basilio D, Accardi A. (2015) A Proteoliposome-Based Efflux Assay to Determine Single-molecule Properties of Cl- Channels and Transporters. Journal of Visualized Experiments : Jove
Basilio D, Noack K, Picollo A, et al. (2014) Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter. Nature Structural & Molecular Biology. 21: 456-63
Eugenin EA, Basilio D, Sáez JC, et al. (2012) The role of gap junction channels during physiologic and pathologic conditions of the human central nervous system. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 499-518
Castillo JP, De Giorgis D, Basilio D, et al. (2011) Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the giant axon of the Humboldt squid. Proceedings of the National Academy of Sciences of the United States of America. 108: 20556-61
Basilio D, Kienker PK, Briggs SW, et al. (2011) A kinetic analysis of protein transport through the anthrax toxin channel. The Journal of General Physiology. 137: 521-31
Basilio D, Jennings-Antipov LD, Jakes KS, et al. (2011) Trapping a translocating protein within the anthrax toxin channel: implications for the secondary structure of permeating proteins. The Journal of General Physiology. 137: 343-56
Basilio D, Juris SJ, Collier RJ, et al. (2009) Evidence for a proton-protein symport mechanism in the anthrax toxin channel. The Journal of General Physiology. 133: 307-14
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