Nam H. Le, Ph.D.

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Axonal degeneration, peripheral neuropathy, Myelination, Schwann cell metabolism
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"Nam Le"
Mean distance: 18.17 (cluster 11)
 

Parents

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Jeffrey Milbrandt grad student 2005 Washington University
 (Cellular and molecular biology of Schwann cell differentiation.)
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Publications

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Singla R, Mishra A, Lin H, et al. (2022) Haploinsufficiency of a Circadian Clock Gene ( or ) Causes Brain-Wide mTOR Hyperactivation and Autism-like Behavioral Phenotypes in Mice. International Journal of Molecular Sciences. 23
Liu D, Nanclares C, Simbriger K, et al. (2022) Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition. Molecular Psychiatry
Baloh RH, Strickland A, Ryu E, et al. (2009) Congenital hypomyelinating neuropathy with lethal conduction failure in mice carrying the Egr2 I268N mutation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2312-21
Ryu EJ, Wang JY, Le N, et al. (2007) Misexpression of Pou3f1 results in peripheral nerve hypomyelination and axonal loss. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11552-9
Le N, Nagarajan R, Wang JY, et al. (2005) Nab proteins are essential for peripheral nervous system myelination. Nature Neuroscience. 8: 932-40
Le N, Nagarajan R, Wang JY, et al. (2005) Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination. Proceedings of the National Academy of Sciences of the United States of America. 102: 2596-601
Nagarajan R, Le N, Mahoney H, et al. (2002) Deciphering peripheral nerve myelination by using Schwann cell expression profiling. Proceedings of the National Academy of Sciences of the United States of America. 99: 8998-9003
Nagarajan R, Svaren J, Le N, et al. (2001) EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression. Neuron. 30: 355-68
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