Nathaniel D. Huebsch

Affiliations: 
2010 Harvard University, Cambridge, MA, United States 
Area:
Cellular biology; Biomedical engineering; Biophysics
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"Nathaniel Huebsch"
Bio:

Huebsch, Nathaniel D., Integrin-Adhesion Ligand Bonds as 3D Mechanosensors that Modulate Mesenchymal Stem Cell Fate, thesis Harvard University, 2010

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David J. Mooney grad student 2010 Harvard
 (Integrin-Adhesion Ligand Bonds as 3D Mechanosensors that Modulate Mesenchymal Stem Cell Fate.)
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Publications

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Huebsch N, Charrez B, Neiman G, et al. (2022) Metabolically driven maturation of human-induced-pluripotent-stem-cell-derived cardiac microtissues on microfluidic chips. Nature Biomedical Engineering. 6: 372-388
Huebsch N. (2019) Translational mechanobiology: Designing synthetic hydrogel matrices for improved in vitro models and cell-based therapies. Acta Biomaterialia. 94: 97-111
Loskill P, Huebsch N. (2019) Engineering Tissues from Induced Pluripotent Stem Cells. Tissue Engineering. Part A. 25: 707-710
Ma Z, Huebsch N, Koo S, et al. (2018) Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload. Nature Biomedical Engineering. 2: 955-967
Tveito A, Jæger KH, Huebsch N, et al. (2018) Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems. Scientific Reports. 8: 17626
Cipitria A, Boettcher K, Schoenhals S, et al. (2017) In-situ tissue regeneration through SDF-1α driven cell recruitment and stiffness-mediated bone regeneration in a critical-sized segmental femoral defect. Acta Biomaterialia
Huebsch N, Loskill P, Deveshwar N, et al. (2016) Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. Scientific Reports. 6: 24726
Mandegar MA, Huebsch N, Frolov EB, et al. (2016) CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell
Chaudhuri O, Gu L, Klumpers D, et al. (2015) Hydrogels with tunable stress relaxation regulate stem cell fate and activity. Nature Materials
Huebsch N, Lippens E, Lee K, et al. (2015) Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation. Nature Materials
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