Jeffrey D. Rothstein

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Transporter, ALS
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Publications

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Shefner JM, Bedlack R, Andrews JA, et al. (2022) Amyotrophic Lateral Sclerosis Clinical Trials and Interpretation of Functional End Points and Fluid Biomarkers: A Review. Jama Neurology
Maragakis NJ, Rothstein JD. (2022) The Evolving Landscape of Motor Neuron Disease Therapeutics. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics
Baxi EG, Thompson T, Li J, et al. (2022) Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines. Nature Neuroscience. 25: 226-237
Li J, Lim RG, et al. (2021) An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients. Iscience. 24: 103221
Johnson JO, Chia R, Miller DE, et al. (2021) Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis. Jama Neurology
Coyne AN, Baskerville V, Zaepfel BL, et al. (2021) Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS. Science Translational Medicine. 13
Coyne AN, Zaepfel BL, Hayes L, et al. (2020) GC Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD. Neuron
Andrews JA, Berry JD, Baloh RH, et al. (2020) Amyotrophic Lateral Sclerosis Care and Research in the USA During the COVID-19 Pandemic: Challenges and Opportunities. Muscle & Nerve
Hayes LR, Duan L, Bowen K, et al. (2020) arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import. Elife. 9
Westergard T, Rothstein JD. (2020) Astrocyte Diversity: Current Insights and Future Directions. Neurochemical Research
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