Vikram G. Shakkottai, Ph.D.
Affiliations: | University of California, Irvine, Irvine, CA |
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"Vikram Shakkottai"Mean distance: 19.36 (cluster 11)
Parents
Sign in to add mentor| George Chandy | grad student | 2004 | UC Irvine | |
| (The role of small -conductance calcium-activated potassium channels in the mammalian nervous system and neurological disease.) | ||||
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Publications
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| Huang H, Shakkottai VG. (2023) Targeting Ion Channels and Purkinje Neuron Intrinsic Membrane Excitability as a Therapeutic Strategy for Cerebellar Ataxia. Life (Basel, Switzerland). 13 |
| Bushart DD, Shakkottai VG. (2022) Vulnerability of Human Cerebellar Neurons to Degeneration in Ataxia-Causing Channelopathies. Frontiers in Systems Neuroscience. 16: 908569 |
| Srinivasan SR, Huang H, Chang WC, et al. (2022) Discovery of novel activators of large-conductance calcium-activated potassium channels for the treatment of cerebellar ataxia. Molecular Pharmacology |
| Chopra R, Bushart DD, Cooper JP, et al. (2020) Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1. Human Molecular Genetics |
| Bushart DD, Zalon AJ, Zhang H, et al. (2020) Antisense Oligonucleotide Therapy Targeted Against ATXN3 Improves Potassium Channel-Mediated Purkinje Neuron Dysfunction in Spinocerebellar Ataxia Type 3. Cerebellum (London, England) |
| Conway KS, Camelo-Piragua S, Fisher-Hubbard A, et al. (2020) Multiple system atrophy pathology is associated with primary Sjögren's syndrome. Jci Insight. 5 |
| Costa MDC, Radzwion M, McLoughlin HS, et al. (2020) In Vivo Molecular Signatures of Cerebellar Pathology in Spinocerebellar Ataxia Type 3. Movement Disorders : Official Journal of the Movement Disorder Society |
| Yang CY, Lai RY, Amokrane N, et al. (2020) Dysphagia in spinocerebellar ataxias type 1, 2, 3 and 6. Journal of the Neurological Sciences. 415: 116878 |
| Gan SR, Figueroa KP, Xu HL, et al. (2020) The impact of ethnicity on the clinical presentations of spinocerebellar ataxia type 3. Parkinsonism & Related Disorders. 72: 37-43 |
| Stoyas CA, Bushart DD, Switonski PM, et al. (2019) Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7. Neuron |