Victor Chi, Ph.D.
Affiliations: | Biomedical Sciences - Ph.D. | University of California, Irvine, Irvine, CA |
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"Victor Chi"Mean distance: 19.36 (cluster 11)
Parents
Sign in to add mentor| George Chandy | grad student | 2012 | UC Irvine | |
| (Characterization and development of a selective Kv1.3 channel blocker, ShK-186, for treatment of autoimmune disorders.) | ||||
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| Wang RE, Wang Y, Zhang Y, et al. (2016) Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant. Proceedings of the National Academy of Sciences of the United States of America. 113: 11501-11506 |
| Tarcha EJ, Chi V, Muñoz-ElÃas EJ, et al. (2012) Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease. The Journal of Pharmacology and Experimental Therapeutics. 342: 642-53 |
| Chi V, Pennington MW, Norton RS, et al. (2012) Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases. Toxicon : Official Journal of the International Society On Toxinology. 59: 529-46 |
| Rangaraju S, Khoo KK, Feng ZP, et al. (2010) Potassium channel modulation by a toxin domain in matrix metalloprotease 23. The Journal of Biological Chemistry. 285: 9124-36 |
| Rangaraju S, Chi V, Pennington MW, et al. (2009) Kv1.3 potassium channels as a therapeutic target in multiple sclerosis. Expert Opinion On Therapeutic Targets. 13: 909-24 |
| Pennington MW, Beeton C, Galea CA, et al. (2009) Engineering a stable and selective peptide blocker of the Kv1.3 channel in T lymphocytes. Molecular Pharmacology. 75: 762-73 |
| Matheu MP, Beeton C, Garcia A, et al. (2008) Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block. Immunity. 29: 602-14 |
| Beeton C, Smith BJ, Sabo JK, et al. (2008) The D-diastereomer of ShK toxin selectively blocks voltage-gated K+ channels and inhibits T lymphocyte proliferation. The Journal of Biological Chemistry. 283: 988-97 |