Andrew J. Alt, Ph.D.
Affiliations: | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
behavioral pharmacologyGoogle:
"Andrew Alt"Mean distance: 16.18 (cluster 19) | S | N | B | C | P |
Parents
Sign in to add mentor| James H. Woods | grad student | 2000 | University of Michigan | |
| (Activation of guanine nucleotide binding proteins by opioid receptors.) | ||||
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Publications
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| Olson KM, Campbell A, Alt A, et al. (2022) Finding the Perfect Fit: Conformational Biosensors to Determine the Efficacy of GPCR Ligands. Acs Pharmacology & Translational Science. 5: 694-709 |
| Kandasamy R, Hillhouse TM, Livingston KE, et al. (2021) Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Scott CE, Tang Y, Alt A, et al. (2019) Identification and biochemical analyses of selective CB agonists. European Journal of Pharmacology |
| Livingston KE, Stanczyk MA, Burford N, et al. (2017) Pharmacological Evidence for a Putative Conserved Allosteric Site on Opioid Receptors. Molecular Pharmacology |
| Carpenter J, Wang Y, Wu G, et al. (2017) Utilization of an active site mutant receptor for the identification of potent and selective atypical 5-HT2C receptor agonists. Journal of Medicinal Chemistry |
| Winters BL, Gregoriou GC, Kissiwaa SA, et al. (2017) Endogenous opioids regulate moment-to-moment neuronal communication and excitability. Nature Communications. 8: 14611 |
| Alt A. (2016) Overview of Critical Parameters for the Design and Execution of a High-Throughput Screen for Allosteric Ligands. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. 74: 9.20.1-9.20.23 |
| Shang Y, Yeatman HR, Provasi D, et al. (2016) Proposed Mode of Binding and Action of Positive Allosteric Modulators at Opioid Receptors. Acs Chemical Biology |
| Alt A, Pendri A, Bertekap RL, et al. (2015) Evidence for classical cholinergic toxicity associated with selective activation of M1 muscarinic receptors. The Journal of Pharmacology and Experimental Therapeutics |
| Bisignano P, Burford NT, Shang Y, et al. (2015) Ligand-Based Discovery of a New Scaffold for Allosteric Modulation of the μ-Opioid Receptor. Journal of Chemical Information and Modeling |