Erin J. Whalen, Ph.D.

University of Iowa, Iowa City, IA 
mood, thirst, cardiovascular homeostasis
"Erin Whalen"
Mean distance: 16.7 (cluster 19)


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Alan K. Johnson grad student 2000 University of Iowa
 (Nitrosyl factors regulate G(S) protein-coupled receptor signal transduction in vivo.)
Robert J. Lefkowitz post-doc Duke
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Yamada K, Park HM, Rigel DF, et al. (2016) Small-molecule WNK inhibition regulates cardiovascular and renal function. Nature Chemical Biology
Whalen EJ, Johnson AK, Lewis SJ. (2014) Hemodynamic responses elicited by systemic injections of isotonic and hypertonic saline in hemorrhaged rats. Microvascular Research. 91: 22-9
Zennadi R, Whalen EJ, Soderblom EJ, et al. (2012) Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium. Blood. 119: 1217-27
Hara MR, Kovacs JJ, Whalen EJ, et al. (2011) A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature. 477: 349-53
Boerrigter G, Lark MW, Whalen EJ, et al. (2011) Cardiorenal actions of TRV120027, a novel ß-arrestin-biased ligand at the angiotensin II type I receptor, in healthy and heart failure canines: a novel therapeutic strategy for acute heart failure. Circulation. Heart Failure. 4: 770-8
Whalen EJ, Rajagopal S, Lefkowitz RJ. (2011) Therapeutic potential of β-arrestin- and G protein-biased agonists. Trends in Molecular Medicine. 17: 126-39
Violin JD, DeWire SM, Yamashita D, et al. (2010) Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance. The Journal of Pharmacology and Experimental Therapeutics. 335: 572-9
Xie L, Xiao K, Whalen EJ, et al. (2009) Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL. Science Signaling. 2: ra33
Zidar DA, Violin JD, Whalen EJ, et al. (2009) Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands. Proceedings of the National Academy of Sciences of the United States of America. 106: 9649-54
Walters RW, Shukla AK, Kovacs JJ, et al. (2009) beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice. The Journal of Clinical Investigation. 119: 1312-21
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