Talene A. Yacoubian, Ph.D.

Affiliations: 
Duke University, Durham, NC 
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"Talene Yacoubian"
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Parents

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Donald C. Lo grad student 2000 Duke
 (Differential regulation of dendritic growth by the TrkB neurotrophin receptor isoforms.)
David G. Standaert post-doc 2005-2007 Harvard Medical School
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Publications

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Yacoubian TA, Fang YD, Gerstenecker A, et al. (2023) Brain and Systemic Inflammation in De Novo Parkinson's Disease. Movement Disorders : Official Journal of the Movement Disorder Society
Fang YD, McConathy JE, Yacoubian TA, et al. (2022) Image Quantification for TSPO PET with a Novel Image-Derived Input Function Method. Diagnostics (Basel, Switzerland). 12
Kuo SH, Tasset I, Cheng MM, et al. (2022) Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy. Science Advances. 8: eabm6393
Xu E, Boddu R, Abdelmotilib HA, et al. (2022) Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain. Molecular Neurodegeneration. 17: 7
Carlisle SM, Qin H, Hendrickson RC, et al. (2021) Sex-based differences in the activation of peripheral blood monocytes in early Parkinson disease. Npj Parkinson's Disease. 7: 36
Underwood R, Gannon M, Pathak A, et al. (2021) 14-3-3 mitigates alpha-synuclein aggregation and toxicity in the in vivo preformed fibril model. Acta Neuropathologica Communications. 9: 13
Underwood R, Wang B, Carico C, et al. (2020) The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of alpha-synuclein. The Journal of Biological Chemistry
Wang B, Underwood R, Kamath A, et al. (2018) 14-3-3 proteins reduce cell-to-cell transfer and propagation of pathogenic alpha-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
McFerrin MB, Chi X, Cutter G, et al. (2017) Dysregulation of 14-3-3 proteins in neurodegenerative diseases with Lewy body or Alzheimer pathology. Annals of Clinical and Translational Neurology. 4: 466-477
Apetauerova D, Scala SA, Hamill RW, et al. (2016) CoQ10 in progressive supranuclear palsy: A randomized, placebo-controlled, double-blind trial. Neurology® Neuroimmunology & Neuroinflammation. 3: e266
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