Talene A. Yacoubian, Ph.D.

Affiliations: 
Duke University, Durham, NC 
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"Talene Yacoubian"
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Parents

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Donald C. Lo grad student 2000 Duke
 (Differential regulation of dendritic growth by the TrkB neurotrophin receptor isoforms.)
David G. Standaert post-doc 2005-2007 Harvard Medical School
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Publications

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Scholz K, Pattanayak R, Roschonporn E, et al. (2024) Rab27b promotes lysosomal function and alpha-synuclein clearance in neurons. Biorxiv : the Preprint Server For Biology
Yuan Y, Li H, Sreeram K, et al. (2024) Single molecule array measures of LRRK2 kinase activity in serum link Parkinson's disease severity to peripheral inflammation. Molecular Neurodegeneration. 19: 47
Yuan Y, Li H, Sreeram K, et al. (2024) Single molecule array measures of LRRK2 kinase activity in serum link Parkinson's disease severity to peripheral inflammation. Biorxiv : the Preprint Server For Biology
Yacoubian TA, Fang YD, Gerstenecker A, et al. (2023) Brain and Systemic Inflammation in De Novo Parkinson's Disease. Movement Disorders : Official Journal of the Movement Disorder Society
Fang YD, McConathy JE, Yacoubian TA, et al. (2022) Image Quantification for TSPO PET with a Novel Image-Derived Input Function Method. Diagnostics (Basel, Switzerland). 12
Kuo SH, Tasset I, Cheng MM, et al. (2022) Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy. Science Advances. 8: eabm6393
Xu E, Boddu R, Abdelmotilib HA, et al. (2022) Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain. Molecular Neurodegeneration. 17: 7
Carlisle SM, Qin H, Hendrickson RC, et al. (2021) Sex-based differences in the activation of peripheral blood monocytes in early Parkinson disease. Npj Parkinson's Disease. 7: 36
Underwood R, Gannon M, Pathak A, et al. (2021) 14-3-3 mitigates alpha-synuclein aggregation and toxicity in the in vivo preformed fibril model. Acta Neuropathologica Communications. 9: 13
Underwood R, Wang B, Carico C, et al. (2020) The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of alpha-synuclein. The Journal of Biological Chemistry
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