Kathryn A. Lindl, Ph.D.

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular mechanisms underlying neuronal loss in neurodegenerative disorders
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"Kathryn Lindl"
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Kelly L. Jordan-Sciutto grad student 2010 Penn
 (Activation of the integrated stress response in HIV-associated neurocognitive disorder.)
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Publications

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Ting JH, Marks DR, Schleidt SS, et al. (2014) Targeted gene mutation of E2F1 evokes age-dependent synaptic disruption and behavioral deficits. Journal of Neurochemistry. 129: 850-63
Akay C, Cooper M, Odeleye A, et al. (2014) Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system. Journal of Neurovirology. 20: 39-53
Wang Y, Zyskind JW, Colacurcio DJ, et al. (2012) Differential roles for caspase-mediated and calpain-mediated cell death in 1- and 3-week-old rat cortical cultures. Neuroreport. 23: 1052-8
Akay C, Lindl KA, Shyam N, et al. (2012) Activation status of integrated stress response pathways in neurones and astrocytes of HIV-associated neurocognitive disorders (HAND) cortex. Neuropathology and Applied Neurobiology. 38: 175-200
Akay C, Lindl KA, Wang Y, et al. (2011) Site-specific hyperphosphorylation of pRb in HIV-induced neurotoxicity. Molecular and Cellular Neurosciences. 47: 154-65
White MG, Wang Y, Akay C, et al. (2011) Parallel high throughput neuronal toxicity assays demonstrate uncoupling between loss of mitochondrial membrane potential and neuronal damage in a model of HIV-induced neurodegeneration. Neuroscience Research. 70: 220-9
Wang Y, Shyam N, Ting JH, et al. (2010) E2F1 localizes predominantly to neuronal cytoplasm and fails to induce expression of its transcriptional targets in human immunodeficiency virus-induced neuronal damage. Neuroscience Letters. 479: 97-101
Lindl KA, Marks DR, Kolson DL, et al. (2010) HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 5: 294-309
Lindl KA, Jordan-Sciutto KL. (2008) Examining the endogenous antioxidant response through immunofluorescent analysis of Nrf2 in tissue. Methods in Molecular Biology (Clifton, N.J.). 477: 229-43
Lindl KA, Akay C, Wang Y, et al. (2007) Expression of the endoplasmic reticulum stress response marker, BiP, in the central nervous system of HIV-positive individuals. Neuropathology and Applied Neurobiology. 33: 658-69
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