Ramee Lee, Ph.D.

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Hematology Oncology/Neurotrophins
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"Ramee Lee"
Mean distance: 17.43 (cluster 32)
 
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Parents

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Barbara L. Hempstead grad student 2003 Weill Cornell Medical College
 (Pro -NGF is a novel ligand that initiates apoptosis through a complex with p75 and sortilin.)
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Publications

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Teng HK, Teng KK, Lee R, et al. (2005) ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5455-63
Pedraza CE, Podlesniy P, Vidal N, et al. (2005) Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR. The American Journal of Pathology. 166: 533-43
Murray SS, Perez P, Lee R, et al. (2004) A novel p75 neurotrophin receptor-related protein, NRH2, regulates nerve growth factor binding to the TrkA receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2742-9
Harrington AW, Leiner B, Blechschmitt C, et al. (2004) Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury. Proceedings of the National Academy of Sciences of the United States of America. 101: 6226-30
Nykjaer A, Lee R, Teng KK, et al. (2004) Sortilin is essential for proNGF-induced neuronal cell death. Nature. 427: 843-8
Beattie MS, Harrington AW, Lee R, et al. (2002) ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury. Neuron. 36: 375-86
Lee R, Kermani P, Teng KK, et al. (2001) Regulation of cell survival by secreted proneurotrophins. Science (New York, N.Y.). 294: 1945-8
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