Brian C. Kraemer, Ph.D.
Affiliations: | University of Wisconsin, Madison, Madison, WI |
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"Brian Kraemer"Mean distance: 18.94 (cluster 32) | S | N | B | C | P |
Parents
Sign in to add mentor| Marvin Wickens | grad student | 2000 | UW Madison | |
| (Identification and characterization RNA -binding proteins involved in post-transcriptional control of Caenorhabditis elegans germline development.) | ||||
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Publications
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| Kow RL, Black AH, Henderson BP, et al. (2023) Sut-6/NIPP1 modulates tau toxicity. Human Molecular Genetics |
| McMillan PJ, Benbow SJ, Uhrich R, et al. (2023) Tau-RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change. Brain : a Journal of Neurology |
| Eck RJ, Kow RL, Black AH, et al. (2022) SPOP loss of function protects against tauopathy. Proceedings of the National Academy of Sciences of the United States of America. 120: e2207250120 |
| Kow RL, Black AH, Saxton AD, et al. (2022) Loss of aly/ALYREF suppresses toxicity in both tau and TDP-43 models of neurodegeneration. Geroscience |
| McMillan PJ, Strovas TJ, Baum M, et al. (2021) Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer's disease. Acta Neuropathologica Communications. 9: 117 |
| Kow RL, Strovas TJ, McMillan PJ, et al. (2020) Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes. Neurobiology of Disease. 147: 105148 |
| Baker JD, Uhrich RL, Strovas TJ, et al. (2020) AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting Therapeutic Discovery. Slas Discovery : Advancing Life Sciences R & D. 2472555220958387 |
| Baker JD, Uhrich RL, Strovas TJ, et al. (2020) Targeting pathological tau by small molecule inhibition of the poly(A):MSUT2 RNA-protein interaction. Acs Chemical Neuroscience |
| Lee EG, Tulloch J, Chen S, et al. (2020) Redefining transcriptional regulation of the APOE gene and its association with Alzheimer's disease. Plos One. 15: e0227667 |
| Baker JD, Kraemer BC. (2020) Inhibition of the MSUT2: RNA interaction for the treatment of tauopathies Alzheimer's & Dementia. 16 |