Craig R. Stumpf, Ph.D.

Affiliations: 
University of Wisconsin, Madison, Madison, WI 
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"Craig Stumpf"
Mean distance: 18.94 (cluster 32)
 
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Marvin Wickens grad student 2008 UW Madison
 (Diverse PUFs with distinct PBEs: Characterization of PUF-RNA binding specificity.)
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Publications

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Shukla T, de la Peña JB, Perish JM, et al. (2020) A Highly Selective MNK Inhibitor Rescues Deficits Associated with Fragile X Syndrome in Mice. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics
Xu Y, Poggio M, Jin HY, et al. (2019) Translation control of the immune checkpoint in cancer and its therapeutic targeting. Nature Medicine
Young NP, Stumpf CR, Chen J, et al. (2019) Abstract 4343: A focused CRISPR screen to identify synthetic lethal interactions with the novel eIF4A inhibitor eFT226 in KRAS driven NSCLC Cancer Research. 79: 4343-4343
Stumpf CR, Goel VK, Sharma RK, et al. (2019) Abstract 4142: Physical and functional interactions between MNK and mTOR signaling regulate the activation and differentiation of T cells Cancer Research. 79: 4142-4142
Chiang GG, Parker GS, Hung IN, et al. (2019) Abstract 1302: Targeting hormone receptor-dependent cancers with potent, selective and orally-available small molecule inhibitors of eIF4E Cancer Research. 79: 1302-1302
Thompson PA, Young NP, Stumpf CR, et al. (2019) Abstract B133: eFT226, a first in class inhibitor of eIF4A1, targets FGFR1/2 and HER2 driven cancers Molecular Cancer Therapeutics. 18
Reich SH, Sprengeler PA, Chiang GG, et al. (2018) Structure-based Design of Pyridone-aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition. Journal of Medicinal Chemistry
Stumpf CR, Chen J, Goel VK, et al. (2018) Abstract 3855: Inhibition of MNK by eFT508 reprograms T-cell signaling to promote an antitumor immune response Cancer Research. 78: 3855-3855
Webster KR, Goel VK, Staunton J, et al. (2017) Abstract PR11: eFT508: An oral, potent and highly selective inhibitor of MNK1 and MNK2, promotes anti-tumor immunity as a monotherapy and in combination with immune checkpoint blockade Cancer Research. 77
Webster KR, Goel VK, Staunton J, et al. (2017) Abstract 596: eFT508, a potent and highly selective inhibitor of MNK1/2 regulates immune checkpoint and cytokine expression promoting anti-tumor immunity Cancer Research. 77: 596-596
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