Roger Lefort, Ph.D.

Pathobiology and Molecular Medicine Columbia University, New York, NY 
Neural development, cytoskeleton
"Roger Lefort"
Mean distance: 16.44 (cluster 11)


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Michael L. Shelanski grad student 2011 Columbia
 (Investigating the Role of the Amyloid Precursor Protein in the Pathogenesis of Alzheimer's Disease.)


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Caghan Kizil collaborator
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Vardarajan BN, Tosto G, Lefort R, et al. (2017) Ultra-rare mutations in SRCAP segregate in Caribbean Hispanic families with Alzheimer disease. Neurology. Genetics. 3: e178
Aubry S, Shin W, Crary JF, et al. (2015) Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression. Plos One. 10: e0120352
Shelanski M, Lefort R. (2015) Stuck in the mire. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 1-2
Pianu B, Lefort R, Thuiliere L, et al. (2014) The Aβ₁₋₄₂ peptide regulates microtubule stability independently of tau. Journal of Cell Science. 127: 1117-27
Pozueta J, Lefort R, Ribe EM, et al. (2013) Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice. Nature Communications. 4: 1939
Pozueta J, Lefort R, Shelanski ML. (2013) Synaptic changes in Alzheimer's disease and its models. Neuroscience. 251: 51-65
Lefort R, Pozueta J, Shelanski M. (2012) Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10674-85
Vitolo O, Gong B, Cao Z, et al. (2009) Protection against beta-amyloid induced abnormal synaptic function and cell death by Ginkgolide J. Neurobiology of Aging. 30: 257-65
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